Yair Lotan

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. doi request reprint Prospective evaluation of a molecular marker panel for prediction of recurrence and cancer-specific survival after radical cystectomy
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center Dallas, TX 75390, USA
    Eur Urol 64:465-71. 2013
  2. doi request reprint Comprehensive handbook for developing a bladder cancer cystectomy database
    Yair Lotan
    The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Urol Oncol 31:812-26. 2013
  3. doi request reprint Impact of fluid intake in the prevention of urinary system diseases: a brief review
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Curr Opin Nephrol Hypertens 22:S1-10. 2013
  4. doi request reprint Primary prevention of nephrolithiasis is cost-effective for a national healthcare system
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    BJU Int 110:E1060-7. 2012
  5. doi request reprint Increased water intake as a prevention strategy for recurrent urolithiasis: major impact of compliance on cost-effectiveness
    Y Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Urol 189:935-9. 2013
  6. doi request reprint Evaluation of vitamin E and selenium supplementation for the prevention of bladder cancer in SWOG coordinated SELECT
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 187:2005-10. 2012
  7. ncbi request reprint Prevention of bladder cancer recurrence by retinoic acid-ketoconazole: a promising strategy?
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Cancer Biol Ther 7:101-2. 2008
  8. doi request reprint Role of biomarkers to predict outcomes and response to therapy
    Yair Lotan
    Department of Urology, The University of Texas, Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Urol Oncol 28:97-101. 2010
  9. doi request reprint Economics of robotics in urology
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Curr Opin Urol 20:92-7. 2010
  10. doi request reprint Key concerns about the current state of bladder cancer: a position paper from the Bladder Cancer Think Tank, the Bladder Cancer Advocacy Network, and the Society of Urologic Oncology
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 115:4096-103. 2009

Collaborators

Detail Information

Publications121 found, 100 shown here

  1. doi request reprint Prospective evaluation of a molecular marker panel for prediction of recurrence and cancer-specific survival after radical cystectomy
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center Dallas, TX 75390, USA
    Eur Urol 64:465-71. 2013
    ..There are no prospective studies validating the clinical utility of markers in bladder cancer...
  2. doi request reprint Comprehensive handbook for developing a bladder cancer cystectomy database
    Yair Lotan
    The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Urol Oncol 31:812-26. 2013
    ..In an effort to standardize data collection for research regarding bladder cancer, the Bladder Cancer Working Group sought to provide a handbook that can be used as a guide for prospective or retrospective data collection...
  3. doi request reprint Impact of fluid intake in the prevention of urinary system diseases: a brief review
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Curr Opin Nephrol Hypertens 22:S1-10. 2013
    ....
  4. doi request reprint Primary prevention of nephrolithiasis is cost-effective for a national healthcare system
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    BJU Int 110:E1060-7. 2012
    ..Future studies will need to assess the feasibility and effectiveness of such an approach in a population...
  5. doi request reprint Increased water intake as a prevention strategy for recurrent urolithiasis: major impact of compliance on cost-effectiveness
    Y Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Urol 189:935-9. 2013
    ..We evaluated the economic impact of preventing recurrent stones using a strategy of increased water intake and determined the impact of compliance on cost-effectiveness for the French health care system...
  6. doi request reprint Evaluation of vitamin E and selenium supplementation for the prevention of bladder cancer in SWOG coordinated SELECT
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 187:2005-10. 2012
    ..Epidemiological and biological evidence suggests a preventive effect of selenium and vitamin E on bladder cancer. We assessed the effect of selenium and/or vitamin E on bladder cancer development...
  7. ncbi request reprint Prevention of bladder cancer recurrence by retinoic acid-ketoconazole: a promising strategy?
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Cancer Biol Ther 7:101-2. 2008
  8. doi request reprint Role of biomarkers to predict outcomes and response to therapy
    Yair Lotan
    Department of Urology, The University of Texas, Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Urol Oncol 28:97-101. 2010
    ..Furthermore, markers may guide targeted therapy. Prospective trials are needed to validate the clinical benefit of assessing expression patterns of molecular biomarkers...
  9. doi request reprint Economics of robotics in urology
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Curr Opin Urol 20:92-7. 2010
    ..This review will discuss general concepts of health economics and apply them to the application of robotics to urologic procedures...
  10. doi request reprint Key concerns about the current state of bladder cancer: a position paper from the Bladder Cancer Think Tank, the Bladder Cancer Advocacy Network, and the Society of Urologic Oncology
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 115:4096-103. 2009
    ....
  11. doi request reprint Bladder cancer screening in a high risk asymptomatic population using a point of care urine based protein tumor marker
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 182:52-7; discussion 58. 2009
    ..We evaluated whether screening high risk asymptomatic individuals with a bladder tumor marker can lead to earlier detection and resultant down staging of bladder cancer...
  12. ncbi request reprint Despite PSA screening and the control by radical prostatectomy, patients treatment fails and have a PSA recurrence
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75309 9110, USA
    Eur Urol 52:453-4. 2007
  13. doi request reprint Economics and cost of care of stone disease
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Adv Chronic Kidney Dis 16:5-10. 2009
    ..These efforts include improving dietary recommendations, identifying barriers to evaluations and treatment of recurrent stone formers, improving patient compliance with recommendations, and development of new medications...
  14. doi request reprint Are urologists fairly reimbursed for complex procedures: failure of 22 modifier?
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 72:494-7. 2008
    ..The 22 modifier was designed to provide surgeons with additional reimbursement for performing complex procedures. We evaluated whether urologists at a tertiary referral center are reimbursed when using the 22 modifier...
  15. doi request reprint Prospective evaluation of the clinical usefulness of reflex fluorescence in situ hybridization assay in patients with atypical cytology for the detection of urothelial carcinoma of the bladder
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 179:2164-9. 2008
    ..We prospectively evaluated the clinical usefulness of fluorescence in situ hybridization assay for treating patients with atypical cytology who are at risk for bladder cancer...
  16. doi request reprint Impact of risk factors on the performance of the nuclear matrix protein 22 point-of-care test for bladder cancer detection
    Yair Lotan
    Department of Urology, University of Texas, Southwestern Medical Center, Dallas, TX 75390, USA
    BJU Int 101:1362-7. 2008
    ..Newton, MA, USA) for the detection of bladder cancer, as this is a point-of-care assay that measures NMPs in voided urine...
  17. ncbi request reprint Screening for bladder cancer: a perspective
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9110, USA
    World J Urol 26:13-8. 2008
    ..In this article, we will review the pros and cons of bladder cancer screening with a focus on cost-effectiveness and who should be screened...
  18. ncbi request reprint Economics of stone management
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, J8 112, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Urol Clin North Am 34:443-53. 2007
    ..For single and recurrent stone formers, medical prophylactic strategies involving drug therapy are more costly than conservative therapy involving dietary measures alone. However, drug strategies yield fewer stone recurrences...
  19. ncbi request reprint Cost-effectiveness of bladder cancer screening
    Yair Lotan
    Assistant Professor of Urology, Department of Urology, The University of Texas, Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9110, USA
    Expert Rev Pharmacoecon Outcomes Res 7:627-32. 2007
    ..Studies need to be performed to evaluate the feasibility and cost-effectiveness of screening high-risk populations such as smokers...
  20. doi request reprint Considerations on implementing diagnostic markers into clinical decision making in bladder cancer
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Urol Oncol 28:441-8. 2010
    ..Moreover, we attempt to outline criteria for the clinical utility of new bladder cancer diagnostic markers...
  21. ncbi request reprint The value of your time: evaluation of effects of changes in medicare reimbursement rates on the practice of urology
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Urol 172:1958-62. 2004
    ..We studied the effect of these changes on hourly reimbursement rates for various services provided by urologists...
  22. ncbi request reprint The percent of biopsy cores positive for cancer is a predictor of advanced pathological stage and poor clinical outcomes in patients treated with radical prostatectomy
    Yair Lotan
    Departments of Urology and Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 171:2209-14. 2004
    ..We examined if the percent of positive biopsies is associated with features of biologically aggressive prostate cancer, biochemical progression and development of distant metastases in patients undergoing radical prostatectomy (RP)...
  23. doi request reprint Cost-effectiveness of primary prevention strategies for nephrolithiasis
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Urol 186:550-5. 2011
    ..Stone disease is a highly prevalent condition associated with substantial cost and morbidity. We evaluated the cost-effectiveness of a primary prevention strategy...
  24. ncbi request reprint International comparison of cost effectiveness of medical management strategies for nephrolithiasis
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Urol Res 33:223-30. 2005
    ..The differential resource allocation to different components of a healthcare system (i.e. subsidized medication versus surgical treatment) in different countries determines the cost effectiveness of various treatment strategies...
  25. ncbi request reprint The new economics of radical prostatectomy: cost comparison of open, laparoscopic and robot assisted techniques
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 172:1431-5. 2004
    ..We evaluated the costs components of laparoscopic (LRP) and robot assisted prostatectomy (RAP), and compared their costs to those of open radical retropubic prostatectomy (RRP)...
  26. ncbi request reprint A cost comparison of nephron-sparing surgical techniques for renal tumour
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 95:1039-42. 2005
    ..To compare costs associated with open partial nephrectomy (OPN), laparoscopic PN (LPN) and percutaneous radiofrequency ablation (PRF) in consecutive patients undergoing nephron-sparing surgery...
  27. doi request reprint The effect of the approach to radical prostatectomy on the profitability of hospitals and surgeons
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 105:1531-5. 2010
    ....
  28. ncbi request reprint Lymphovascular invasion is independently associated with overall survival, cause-specific survival, and local and distant recurrence in patients with negative lymph nodes at radical cystectomy
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9110, USA
    J Clin Oncol 23:6533-9. 2005
    ..We hypothesized that bladder cancer patients with associated lymphovascular invasion (LVI) are at increased risk of occult metastases...
  29. ncbi request reprint Implications of the prostate cancer prevention trial: a decision analysis model of survival outcomes
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9110, USA
    J Clin Oncol 23:1911-20. 2005
    ..To assess the estimated effect of finasteride prevention of prostate cancer on overall survival...
  30. doi request reprint Is robotic surgery cost-effective: no
    Yair Lotan
    Department of Urology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
    Curr Opin Urol 22:66-9. 2012
    ..This review will evaluate the cost-effectiveness of using robotics in urologic surgery...
  31. doi request reprint Predictive value of combined immunohistochemical markers in patients with pT1 urothelial carcinoma at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 182:78-84; discussion 84. 2009
    ..We tested whether the combination of immunohistochemical markers could risk stratify cases of pT1 urothelial carcinoma of the bladder at radical cystectomy...
  32. doi request reprint Predictive value of the differential expression of the urokinase plasminogen activation axis in radical prostatectomy patients
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 55:1124-33. 2009
    ..This axis is involved in cell proliferation, angiogenesis, extracellular matrix degradation, invasion, and metastases...
  33. doi request reprint Predicting clinical outcomes after radical nephroureterectomy for upper tract urothelial carcinoma
    Eugene K Cha
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 61:818-25. 2012
    ..Novel prognostic factors for patients after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) have recently been described...
  34. doi request reprint Oncological outcomes after radical nephroureterectomy for upper tract urothelial carcinoma: comparison over the three decades
    Mehrad Adibi
    Department of Urology, UT Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Int J Urol 19:1060-6. 2012
    ..To evaluate temporal trends in clinicopathological features and oncological outcomes after radical nephroureterectomy for upper tract urothelial carcinoma...
  35. ncbi request reprint Outcomes of radical cystectomy for transitional cell carcinoma of the bladder: a contemporary series from the Bladder Cancer Research Consortium
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:2414-22; discussion 2422. 2006
    ..We present the characteristics and outcomes of a large, contemporary, consecutive series of patients treated with radical cystectomy and pelvic lymphadenectomy for transitional cell carcinoma of the bladder...
  36. doi request reprint Impact of smoking and smoking cessation on outcomes in bladder cancer patients treated with radical cystectomy
    Michael Rink
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 64:456-64. 2013
    ..Cigarette smoking is the best-established risk factor for urothelial carcinoma development...
  37. doi request reprint Survivin as a prognostic marker for urothelial carcinoma of the bladder: a multicenter external validation study
    Shahrokh F Shariat
    Departments of Urology and Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Clin Cancer Res 15:7012-9. 2009
    ..Specimens showing at least 10% reactivity were considered altered. Predictive accuracy was quantified using the concordance index and 200-bootstrap resamples were used to reduce overfit bias...
  38. doi request reprint Combination of multiple molecular markers can improve prognostication in patients with locally advanced and lymph node positive bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 10065, USA
    J Urol 183:68-75. 2010
    ..We also assessed whether the combination of molecular markers is superior to any individual biomarker...
  39. ncbi request reprint Concomitant carcinoma in situ is a feature of aggressive disease in patients with organ-confined TCC at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Eur Urol 51:152-60. 2007
    ..The aim of this study was to assess whether presence of concomitant CIS has a detrimental effect on cancer control after radical cystectomy...
  40. doi request reprint Association of angiogenesis related markers with bladder cancer outcomes and other molecular markers
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 183:1744-50. 2010
    ....
  41. doi request reprint p53 expression in patients with advanced urothelial cancer of the urinary bladder
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    BJU Int 105:489-95. 2010
    ..To test whether assessing p53 expression could improve the ability to predict disease recurrence and disease-specific survival in a multi-institutional cohort of patients with advanced urothelial carcinoma of the urinary bladder (UCB)...
  42. doi request reprint Prognostic risk stratification of pathological stage T2N0 bladder cancer after radical cystectomy
    Guru Sonpavde
    Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, USA
    BJU Int 108:687-92. 2011
    ..To stratify risk of pathological (p) T2N0 urothelial carcinoma of the bladder after radical cystectomy (RC) based on pathological factors to facilitate the development of adjuvant therapy trials for high-risk patients...
  43. doi request reprint Multi-institutional validation of the predictive value of Ki-67 labeling index in patients with urinary bladder cancer
    Vitaly Margulis
    Department of Urologic Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA
    J Natl Cancer Inst 101:114-9. 2009
    ....
  44. ncbi request reprint Prostate cancer disease-free survival after radical retropubic prostatectomy in patients older than 70 years compared to younger cohorts
    Bahaa S Malaeb
    Department of Urology, University of Minnesota, Minneapolis, MN 55455, USA
    Urol Oncol 25:291-7. 2007
    ..To evaluate the feasibility of radical retropubic prostatectomy (RRP) as an option for treating men older than 70 years with organ confined prostate cancer and to compare biochemical progression-free survival with younger cohorts...
  45. ncbi request reprint Use of combined apoptosis biomarkers for prediction of bladder cancer recurrence and mortality after radical cystectomy
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Lancet Oncol 8:128-36. 2007
    ....
  46. doi request reprint Impact of renal function on eligibility for chemotherapy and survival in patients who have undergone radical nephro-ureterectomy
    Evanguelos Xylinas
    Department of Urology, Division of Medical Oncology SFS, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    BJU Int 112:453-61. 2013
    ..73 m(2) , respectively. Taken together with the rest of the literature, the findings of the study support the use of cisplatin-based chemotherapy, when indicated, in the neoadjuvant rather than adjuvant setting...
  47. doi request reprint Disease-free survival at 2 or 3 years correlates with 5-year overall survival of patients undergoing radical cystectomy for muscle invasive bladder cancer
    Guru Sonpavde
    Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
    J Urol 185:456-61. 2011
    ..We identified an association between disease-free survival at 2 to 3 years and 5-year overall survival...
  48. doi request reprint Primary adenocarcinoma of the urinary bladder: value of cell cycle biomarkers
    Payal Kapur
    Dept of Pathology, University of Texas Southwestern, 5323 Harry Hines Blvd, Dallas, TX 75390 9110, USA
    Am J Clin Pathol 135:822-30. 2011
    ..04). Stage, lymph node involvement, combined alterations of p27 and Ki-67, and combined alterations of all 5 biomarkers were associated with increased probability of disease recurrence and cancer-specific mortality (P < .05)...
  49. doi request reprint Upper urinary tract urothelial carcinoma with loco-regional nodal metastases: insights from the Upper Tract Urothelial Carcinoma Collaboration
    Ramy F Youssef
    UT Southwestern Medical Center, Dallas, TX, USA
    BJU Int 108:1286-91. 2011
    ..To describe a multicentre experience with preoperative platinum-based chemotherapy before radical nephroureterectomy (RNU) in patients with upper tract urothelial carcinoma (UTUC) with loco-regional nodal metastases...
  50. doi request reprint The impact of previous ureteroscopic tumor ablation on oncologic outcomes after radical nephrouretectomy for upper urinary tract urothelial carcinoma
    Cenk Gurbuz
    University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Endourol 25:775-9. 2011
    ..Our data support the continued role of ureteroscopic ablation of UTUC in appropriately selected patients...
  51. ncbi request reprint Nomograms provide improved accuracy for predicting survival after radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, and The Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, MD, USA
    Clin Cancer Res 12:6663-76. 2006
    ....
  52. ncbi request reprint Caveolin-1 overexpression is associated with aggressive prostate cancer recurrence
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Prostate 67:614-22. 2007
    ....
  53. doi request reprint Urothelial carcinoma at the uretero-enteric junction: multi-center evaluation of oncologic outcomes after radical nephroureterectomy
    Ramy F Youssef
    University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Urol Oncol 31:676-81. 2013
    ..Therefore, we evaluated oncologic outcomes of patients treated for urothelial carcinoma at the UEJ...
  54. doi request reprint Obesity is associated with worse outcomes in patients with T1 high grade urothelial carcinoma of the bladder
    Luis A Kluth
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
    J Urol 190:480-6. 2013
    ..We hypothesized that higher body mass index is associated with worse outcomes in patients with clinical primary T1 high grade urothelial carcinoma of the bladder...
  55. doi request reprint Impact of smoking on oncologic outcomes of upper tract urothelial carcinoma after radical nephroureterectomy
    Michael Rink
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 63:1082-90. 2013
    ..Cigarette smoking is a common risk factor for developing upper tract urothelial carcinoma (UTUC)...
  56. ncbi request reprint Decreased DOC-2/DAB2 expression in urothelial carcinoma of the bladder
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
    Clin Cancer Res 13:4400-6. 2007
    ..Little is known about the expression of this gene in urothelial carcinoma of the bladder (UCB). We profiled DOC-2/DAB2 expression in mouse and human normal and neoplastic urothelia...
  57. doi request reprint Advanced patient age is associated with inferior cancer-specific survival after radical nephroureterectomy
    Shahrokh F Shariat
    University of Texas Southwestern, Dallas, TX, USA
    BJU Int 105:1672-7. 2010
    ..To assess the impact of patient age on outcomes after radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC)...
  58. doi request reprint Prognostic value of extranodal extension and other lymph node parameters in patients with upper tract urothelial carcinoma
    Harun Fajkovic
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10065, USA
    J Urol 187:845-51. 2012
    ..We assessed the prognostic value of extranodal extension and other lymph node parameters in a large multicenter cohort of patients with lymph node metastasis after radical nephroureterectomy...
  59. ncbi request reprint Laparoscopic interstitial laser coagulation of renal tissue with and without hilar occlusion in the porcine model
    Matthew T Gettman
    Department of Pathology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Endourol 16:565-70. 2002
    ..To evaluate the safety and efficacy of interstitial laser coagulation (ILC), applied via a laparoscopic approach, with and without hilar occlusion in the porcine model...
  60. ncbi request reprint Ki-67 is an independent predictor of bladder cancer outcome in patients treated with radical cystectomy for organ-confined disease
    Vitaly Margulis
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 12:7369-73. 2006
    ..We also assessed malignant lymph nodes from 50 of the 226 cystectomy patients...
  61. ncbi request reprint Intermediate comparison of partial nephrectomy and radiofrequency ablation for clinical T1a renal tumours
    Joshua M Stern
    Department of Urology, University of Texas, Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 100:287-90. 2007
    ....
  62. doi request reprint Disease-free survival as a surrogate for overall survival in upper tract urothelial carcinoma
    Harun Fajkovic
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, 525 East 68th St, Starr 900, New York, NY 10065, USA
    World J Urol 31:5-11. 2013
    ..We hypothesized that disease-free survival (DFS) could be a surrogate endpoint for OS in upper tract urothelial carcinoma (UTUC) patients treated with radical nephroureterectomy (RNU)...
  63. doi request reprint The impact of tumor multifocality on outcomes in patients treated with radical nephroureterectomy
    Thomas F Chromecki
    Department of Urology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10065, USA
    Eur Urol 61:245-53. 2012
    ..The prognostic impact of multifocal upper-tract urothelial carcinoma (UTUC) is poorly understood...
  64. ncbi request reprint Cooperative effect of cell-cycle regulators expression on bladder cancer development and biologic aggressiveness
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Mod Pathol 20:445-59. 2007
    ..In contrast to the use of single biological markers, evaluation of their combined status may improve prognostic models and help identify patients who might benefit from adjuvant therapies and in decision-making...
  65. doi request reprint Preoperative multivariable prognostic model for prediction of nonorgan confined urothelial carcinoma of the upper urinary tract
    Vitaly Margulis
    Department of Urology, UT Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 184:453-8. 2010
    ..We created a prognostic tool for the accurate preoperative prediction of nonorgan confined upper tract urothelial carcinoma...
  66. ncbi request reprint Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder
    Jose A Karam
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Urology 70:482-6. 2007
    ..Our objectives were to evaluate the association of survivin expression with the presence of urothelial cell carcinoma of the bladder and clinical outcomes in patients with non-muscle-invasive urothelial cell carcinoma of the bladder...
  67. ncbi request reprint Prognostic value of syndecan-1 expression in patients treated with radical prostatectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    BJU Int 101:232-7. 2008
    ....
  68. doi request reprint The influence of body mass index on the cost of radical prostatectomy for prostate cancer
    Christian Bolenz
    Departments of Urology, University of Texas Southwestern Medical Center at Dallas, TX, USA
    BJU Int 106:1188-93. 2010
    ..to evaluate the impact of obesity on the costs of robotic-assisted (RALP), laparoscopic (LRP) and open retropubic radical prostatectomy (RRP)...
  69. ncbi request reprint Multiple biomarkers improve prediction of bladder cancer recurrence and mortality in patients undergoing cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 112:315-25. 2008
    ....
  70. ncbi request reprint Predictive value of primary Gleason pattern 4 in patients with Gleason score 7 tumours treated with radical prostatectomy
    Seyed M Khoddami
    Department of Urology, The University of Texas South Western Medical Center, Dallas, USA
    BJU Int 94:42-6. 2004
    ..To examine whether Gleason score (GS) 3 + 4 and 4 + 3 cancers at radical prostatectomy behave differently and whether this behaviour is independently associated with prostate cancer outcome...
  71. ncbi request reprint The cost of prostate cancer chemoprevention: a decision analysis model
    Robert S Svatek
    The University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Cancer Epidemiol Biomarkers Prev 15:1485-9. 2006
    ..The public health cost of wide-scale chemoprevention is unclear. We developed a model to help clarify the cost effectiveness of public use of prostate cancer-preventive agents...
  72. doi request reprint Predictive value of plasma hepatocyte growth factor/scatter factor levels in patients with clinically localized prostate cancer
    Amit Gupta
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 14:7385-90. 2008
    ..We assessed whether preoperative plasma levels of HGF can enhance the accuracy of standard models for predicting pathologic features and clinical outcomes...
  73. ncbi request reprint The influence of clinical and pathological stage discrepancy on cancer specific survival in patients treated for renal cell carcinoma
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 176:1321-5; discussion 125. 2006
    ....
  74. ncbi request reprint Discrepancy between clinical and pathologic stage: impact on prognosis after radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 51:137-49; discussion 149-51. 2007
    ..We compared clinical and pathologic staging in a large, contemporary, consecutive series of patients who were treated with radical cystectomy and pelvic lymphadenectomy, and determined the effect of stage discrepancy on outcomes...
  75. pmc Laparoscopic partial nephrectomy using holmium laser in a porcine model
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, 75390 9110, USA
    JSLS 8:51-5. 2004
    ..To evaluate the utility of the holmium laser for partial nephrectomy in a porcine model...
  76. ncbi request reprint Preoperative plasma HER2 and epidermal growth factor receptor for staging and prognostication in patients with clinically localized prostate cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    Clin Cancer Res 13:5377-84. 2007
    ..We tested the hypothesis that plasma levels of HER2 and/or EGFR are associated with prostate cancer stage and prognosis in patients with clinically localized disease...
  77. ncbi request reprint Expression of cyclooxygenase-2 in normal urothelium, and superficial and advanced transitional cell carcinoma of bladder
    Vitaly Margulis
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    J Urol 177:1163-8. 2007
    ....
  78. ncbi request reprint Variability in the performance of nuclear matrix protein 22 for the detection of bladder cancer
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 176:919-26; discussion 926. 2006
    ..We assessed variability in the diagnostic performance of NMP22 for detecting recurrence and progression in patients with Ta, T1, and/or CIS transitional cell carcinoma of the bladder in a large international cohort...
  79. doi request reprint Risk stratification of organ confined bladder cancer after radical cystectomy using cell cycle related biomarkers
    Shahrokh F Shariat
    Department of Urology, Weill Cornell Medical Center, New York, NY, USA
    J Urol 187:457-62. 2012
    ..We tested whether assessing the expression of cell cycle related proteins (p53, pRB, p21 and p27) could predict clinical outcomes after radical cystectomy in patients with organ confined urothelial carcinoma of the bladder...
  80. ncbi request reprint Survivin expression is associated with bladder cancer presence, stage, progression, and mortality
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9110, USA
    Cancer 109:1106-13. 2007
    ....
  81. pmc High-risk patients with hematuria are not evaluated according to guideline recommendations
    Keren Elias
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, TX, USA
    Cancer 116:2954-9. 2010
    ..To determine whether high-risk patients with hematuria receive evaluation according to guideline recommendations...
  82. doi request reprint Cost comparison of robotic, laparoscopic, and open radical prostatectomy for prostate cancer
    Christian Bolenz
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Eur Urol 57:453-8. 2010
    ..Demand and utilization of minimally invasive approaches to radical prostatectomy have increased in recent years, but comparative studies on cost are lacking...
  83. doi request reprint General anesthesia and contrast-enhanced computed tomography to optimize renal percutaneous radiofrequency ablation: multi-institutional intermediate-term results
    Amit Gupta
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Endourol 23:1099-105. 2009
    ..We evaluated intermediate-term outcomes of patients undergoing percutaneous contrast-enhanced computed tomography (CT)-guided radiofrequency ablation (RFA) under general anesthesia (GA) at two high-volume centers...
  84. ncbi request reprint Efficacy of ablative high-dose-per-fraction radiation for implanted human renal cell cancer in a nude mouse model
    Lance Walsh
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 50:795-800; discussion 800. 2006
    ..We investigated the use of ablative hypofractionation in treating human renal cell carcinoma using a nude mouse model...
  85. ncbi request reprint Soluble Fas--a promising novel urinary marker for the detection of recurrent superficial bladder cancer
    Robert S Svatek
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Cancer 106:1701-7. 2006
    ....
  86. doi request reprint Outcomes of patients with clinical T1 grade 3 urothelial cell bladder carcinoma treated with radical cystectomy
    Amit Gupta
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 71:302-7. 2008
    ..The aim of the present study was to assess the pathologic features and clinical outcomes of patients with clinical T1 grade 3 urothelial cell bladder carcinoma (UCBC) treated with radical cystectomy...
  87. ncbi request reprint Cost-effectiveness of a modified care protocol substituting bladder tumor markers for cystoscopy for the followup of patients with transitional cell carcinoma of the bladder: a decision analytical approach
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
    J Urol 167:75-9. 2002
    ....
  88. ncbi request reprint Laparoscopic versus open retroperitoneal lymph node dissection: a cost analysis
    Kenneth Ogan
    Clinical Center for Minimally Invasive Urologic Cancer Treatment, Dallas, Texas, USA
    J Urol 168:1945-9; discussion 1949. 2002
    ....
  89. ncbi request reprint Evaluation of costs and morbidity associated with laparoscopic radiofrequency ablation and laparoscopic partial nephrectomy for treating small renal tumours
    Karim Bensalah
    Department of Urology, University of Texas South western Medical Center at Dallas, Dallas, Texas 75390 9110, USA
    BJU Int 101:467-71. 2008
    ..To compare the costs and morbidity of laparoscopic radiofrequency ablation (LRFA) and laparoscopic partial nephrectomy (LPN) for treating small localized renal tumours...
  90. doi request reprint Cost-effectiveness of prostate cancer chemoprevention: a quality of life-years analysis
    Robert S Svatek
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Cancer 112:1058-65. 2008
    ..8% (risk reduction) but questions remain regarding the cost-effectiveness of widespread utilization. The purpose of the current analysis was to evaluate the cost-effectiveness of chemoprevention utilizing a quality-of-life adjustment...
  91. ncbi request reprint Cost comparison of hand assisted laparoscopic nephrectomy and open nephrectomy: analysis of individual parameters
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 170:752-5. 2003
    ..In response to budgetary pressure at our large county hospital we reviewed the published experience and identified the cost components of HAL that could be targeted to decrease procedure cost...
  92. ncbi request reprint Cost-effective treatment for ureteropelvic junction obstruction: a decision tree analysis
    Matthew T Gettman
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Urol 169:228-32. 2003
    ..We determined the optimal treatment for primary ureteropelvic junction obstruction based on cost using a decision tree model...
  93. ncbi request reprint Contemporary laparoscopic and open radical retropubic prostatectomy: pathologic outcomes and Kattan postoperative nomograms are equivalent
    Sangtae Park
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Urology 69:118-22. 2007
    ....
  94. doi request reprint p53 predictive value for pT1-2 N0 disease at radical cystectomy
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, USA
    J Urol 182:907-13. 2009
    ..We determined whether p53 expression would improve the prediction of disease progression after radical cystectomy for pT1-2N0M0 UCB...
  95. ncbi request reprint Survivin: a promising biomarker for detection and prognosis of bladder cancer
    Vitaly Margulis
    Department of Urology, The University of Texas M D Anderson Cancer Center, Houston, TX, USA
    World J Urol 26:59-65. 2008
    ..These preliminary findings should now be confirmed in large prospective trials. Furthermore, simplified, quantitative and reproducible assays need to be developed and validated for the detection of Survivin and its different isoforms...
  96. doi request reprint Cost utility of prostate cancer chemoprevention with dutasteride in men with an elevated prostate specific antigen
    Robert S Svatek
    Department of Urology, The University of Texas San Antonio, TX, USA
    Cancer Prev Res (Phila) 4:277-83. 2011
    ..8%, but questions remain regarding the cost-effectiveness of widespread utilization. We evaluated the cost utility of chemoprevention using dutasteride in men at elevated risk for CaP...
  97. ncbi request reprint Urinary levels of tumor-associated trypsin inhibitor (TATI) in the detection of transitional cell carcinoma of the urinary bladder
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, 75390 9110, USA
    Eur Urol 48:424-31. 2005
    ....
  98. doi request reprint Mesh kits for anterior vaginal prolapse are not cost effective
    Sunshine Murray
    Department of Urology, University of Texas Southwestern, 5323 Harry Hines Blvd, Dallas, TX 75390 9110, USA
    Int Urogynecol J 22:447-52. 2011
    ..To analyze the cost-effectiveness of traditional anterior colporrhaphy (AC), hand-cut mesh, and mesh kit anterior vaginal prolapse (AVP) repair...
  99. ncbi request reprint Correlation of cyclin D1 and E1 expression with bladder cancer presence, invasion, progression, and metastasis
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center at Dallas, TX 75390 9110, USA
    Hum Pathol 37:1568-76. 2006
    ..Cyclin E1 expression stratifies patients with bladder transitional cell carcinoma into those with more "indolent" behavior and those with features of biologically and clinically aggressive disease...
  100. doi request reprint Nomograms for bladder cancer
    Shahrokh F Shariat
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9110, USA
    Eur Urol 54:41-53. 2008
    ..Physicians need tools to accurately estimate the risk of recurrence and cancer-specific mortality to recommend individualized therapy and to design appropriate clinical trials...
  101. ncbi request reprint Expression of survivin and apoptotic biomarkers in benign prostatic hyperplasia
    Shahrokh F Shariat
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 174:2046-50. 2005
    ..We assessed the differential expression of survivin and other apoptotic markers in stromal and epithelial compartments of benign prostatic hyperplasia (BPH) and normal prostate tissue...