C Lorenzo

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. pmc A1C between 5.7 and 6.4% as a marker for identifying pre-diabetes, insulin sensitivity and secretion, and cardiovascular risk factors: the Insulin Resistance Atherosclerosis Study (IRAS)
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, San Antonio, Texas, USA
    Diabetes Care 33:2104-9. 2010
  2. pmc Impaired fasting glucose and impaired glucose tolerance have distinct lipoprotein and apolipoprotein changes: the insulin resistance atherosclerosis study
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, Texas 78229
    J Clin Endocrinol Metab 98:1622-30. 2013
  3. pmc The association of alanine aminotransferase within the normal and mildly elevated range with lipoproteins and apolipoproteins: the Insulin Resistance Atherosclerosis Study
    C Lorenzo
    Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Diabetologia 56:746-57. 2013
  4. pmc Relationship of insulin sensitivity, insulin secretion, and adiposity with insulin clearance in a multiethnic population: the insulin Resistance Atherosclerosis study
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, San Antonio, TX, USA
    Diabetes Care 36:101-3. 2013
  5. pmc Insulin secretion based on the late oral glucose tolerance test period and incident diabetes: the San Antonio Heart Study
    C Lorenzo
    Division of Clinical Epidemiology, University of Texas Health Science Center KenAnCo Biostatistics San Antonio, Texas 78229, USA
    Diabet Med 29:e151-8. 2012
  6. pmc Impaired glucose tolerance and obesity as effect modifiers of ethnic disparities of the progression to diabetes: the San Antonio Heart Study
    Carlos Lorenzo
    Division of Clinical Epidemiology, UT Health Science Center, San Antonio, Texas, USA
    Diabetes Care 35:2548-52. 2012
  7. pmc Insulin resistance and excess risk of diabetes in Mexican-Americans: the San Antonio Heart Study
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, 7703 Floyd Curl Drive, Room 5 594U, San Antonio, Texas 78229, USA
    J Clin Endocrinol Metab 97:793-9. 2012
  8. pmc Height, ethnicity, and the incidence of diabetes: the San Antonio Heart Study
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78284 7873, USA
    Metabolism 58:1530-5. 2009
  9. doi request reprint Pulse pressure, prehypertension, and mortality: the San Antonio heart study
    Carlos Lorenzo
    Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center, San Antonio, Texas, USA
    Am J Hypertens 22:1219-26. 2009
  10. pmc Insulin resistance, beta-cell dysfunction, and conversion to type 2 diabetes in a multiethnic population: the Insulin Resistance Atherosclerosis Study
    Carlos Lorenzo
    Division of Clinical Epidemiology, University of TexasHealth Science Center, San Antonio, Texas, USA
    Diabetes Care 33:67-72. 2010

Detail Information

Publications32

  1. pmc A1C between 5.7 and 6.4% as a marker for identifying pre-diabetes, insulin sensitivity and secretion, and cardiovascular risk factors: the Insulin Resistance Atherosclerosis Study (IRAS)
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, San Antonio, Texas, USA
    Diabetes Care 33:2104-9. 2010
    ..A1C is an optional method for diagnosing diabetes and also for detecting individuals at increased risk of the disease. However, how A1C compares with fasting (FPG) and 2-h plasma glucose for detecting at-risk individuals is not well known...
  2. pmc Impaired fasting glucose and impaired glucose tolerance have distinct lipoprotein and apolipoprotein changes: the insulin resistance atherosclerosis study
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, Texas 78229
    J Clin Endocrinol Metab 98:1622-30. 2013
    ..These results may help to explain differences in cardiovascular disease risk in the prediabetic state...
  3. pmc The association of alanine aminotransferase within the normal and mildly elevated range with lipoproteins and apolipoproteins: the Insulin Resistance Atherosclerosis Study
    C Lorenzo
    Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Diabetologia 56:746-57. 2013
    ..We examined the extent to which this association was explained by insulin resistance, adiposity, glucose tolerance and chronic inflammation...
  4. pmc Relationship of insulin sensitivity, insulin secretion, and adiposity with insulin clearance in a multiethnic population: the insulin Resistance Atherosclerosis study
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, San Antonio, TX, USA
    Diabetes Care 36:101-3. 2013
    ..We aimed to examine insulin clearance, a compensatory mechanism to changes in insulin sensitivity, across sex, race/ethnicity populations, and varying states of glucose tolerance...
  5. pmc Insulin secretion based on the late oral glucose tolerance test period and incident diabetes: the San Antonio Heart Study
    C Lorenzo
    Division of Clinical Epidemiology, University of Texas Health Science Center KenAnCo Biostatistics San Antonio, Texas 78229, USA
    Diabet Med 29:e151-8. 2012
    ..We therefore investigated the association of the ratio of the area under the insulin curve to the area under the glucose curve from 60 to 120 min (I/G(AUC 60-120) ) with incident diabetes...
  6. pmc Impaired glucose tolerance and obesity as effect modifiers of ethnic disparities of the progression to diabetes: the San Antonio Heart Study
    Carlos Lorenzo
    Division of Clinical Epidemiology, UT Health Science Center, San Antonio, Texas, USA
    Diabetes Care 35:2548-52. 2012
    ..Because impaired fasting glucose (IFG) and obesity were also very prevalent in the DPP, we examined IGT, IFG, and obesity as effect modifiers of ethnic disparities in the San Antonio Heart Study...
  7. pmc Insulin resistance and excess risk of diabetes in Mexican-Americans: the San Antonio Heart Study
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, 7703 Floyd Curl Drive, Room 5 594U, San Antonio, Texas 78229, USA
    J Clin Endocrinol Metab 97:793-9. 2012
    ..Mexican-Americans have more diabetes than non-Hispanic whites, but the extent to which insulin resistance and insulin secretion explain the ethnic difference is unknown...
  8. pmc Height, ethnicity, and the incidence of diabetes: the San Antonio Heart Study
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78284 7873, USA
    Metabolism 58:1530-5. 2009
    ....
  9. doi request reprint Pulse pressure, prehypertension, and mortality: the San Antonio heart study
    Carlos Lorenzo
    Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center, San Antonio, Texas, USA
    Am J Hypertens 22:1219-26. 2009
    ..Nevertheless, the impact of pulse pressure on the relationship between prehypertension and mortality is not known in individuals who are free of diabetes and cardiovascular disease...
  10. pmc Insulin resistance, beta-cell dysfunction, and conversion to type 2 diabetes in a multiethnic population: the Insulin Resistance Atherosclerosis Study
    Carlos Lorenzo
    Division of Clinical Epidemiology, University of TexasHealth Science Center, San Antonio, Texas, USA
    Diabetes Care 33:67-72. 2010
    ..Furthermore, the strength of these associations has not been tested in different ethnic groups and various states of glucose tolerance, family history of diabetes, and obesity...
  11. pmc Performance characteristics of the new definition of diabetes: the insulin resistance atherosclerosis study
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, San Antonio, Texas, USA
    Diabetes Care 33:335-7. 2010
    ..A1C > or =6.5% has been recently proposed as the defining criterion for diabetes. However, performance characteristics of this definition have not been described...
  12. doi request reprint Relation of direct and surrogate measures of insulin resistance to cardiovascular risk factors in nondiabetic finnish offspring of type 2 diabetic individuals
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, Room 5 594U, San Antonio, Texas 78229, USA
    J Clin Endocrinol Metab 95:5082-90. 2010
    ..Methods to directly measure insulin resistance are invasive, complex, and costly. Surrogate indexes derived from the oral glucose tolerance test (OGTT) have been developed, but few studies have systematically analyzed these indexes...
  13. pmc Disposition index, glucose effectiveness, and conversion to type 2 diabetes: the Insulin Resistance Atherosclerosis Study (IRAS)
    Carlos Lorenzo
    Division of Clinical Epidemiology, University of Texas Health Science Center, San Antonio, Texas, USA
    Diabetes Care 33:2098-103. 2010
    ..Disposition index (DI) and glucose effectiveness (S(G)) are risk factors for diabetes. However, the effect of DI and S(G) on future diabetes has not been examined in large epidemiological studies using direct measures...
  14. pmc Cross-sectional and longitudinal changes of glucose effectiveness in relation to glucose tolerance: the insulin resistance atherosclerosis study
    Carlos Lorenzo
    Division of Clinical Epidemiology, University of Texas Health Science Center, San Antonio, TX, USA
    Diabetes Care 34:1959-64. 2011
    ....
  15. doi request reprint Risk of type 2 diabetes among individuals with high and low glomerular filtration rates
    C Lorenzo
    Department of Medicine, Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284 7873, USA
    Diabetologia 52:1290-7. 2009
    ..Metabolic abnormalities frequently develop prior to the diagnosis of type 2 diabetes and chronic kidney disease. However, it is not known whether GFR predicts the onset of type 2 diabetes...
  16. ncbi request reprint Was the historic contribution of Spain to the Mexican gene pool partially responsible for the higher prevalence of type 2 diabetes in mexican-origin populations? The Spanish Insulin Resistance Study Group, the San Antonio Heart Study, and the Mexico City
    C Lorenzo
    Department of Medicine, Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 78284 7873, USA
    Diabetes Care 24:2059-64. 2001
    ..However, the higher prevalence of type 2 diabetes in Mexican-origin populations might be related, in part, not to Native American genetic admixture but to Spanish genetic admixture...
  17. ncbi request reprint Prevalence of hypertension in Hispanic and non-Hispanic white populations
    Carlos Lorenzo
    Department of Medicine, Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 78284 7873, USA
    Hypertension 39:203-8. 2002
    ..Although we cannot conclude definitively that these differences are genetically driven, our results suggest no relationship between Spanish genetic admixture and the deficit in hypertension prevalence in Mexican-origin populations...
  18. ncbi request reprint Central adiposity determines prevalence differences of the metabolic syndrome
    Carlos Lorenzo
    Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78284 7873, USA
    Obes Res 11:1480-7. 2003
    ..To compare the expression of the metabolic syndrome in Spain and San Antonio, TX, two populations with major differences regarding their cardiovascular risk profile...
  19. ncbi request reprint Lower hypertension risk in Mexico City than in San Antonio
    Carlos Lorenzo
    Department of Medicine, The University of Texas Health Science Center, 7703 Floyd Curl Dr, San Antonio, TX 78220, USA
    Am J Hypertens 18:385-91. 2005
    ..We examined the effects of blood pressure (BP), weight, and weight gain on hypertension risk in two similar ethnic origin populations, subjects in Mexico City and Mexican Americans in San Antonio...
  20. ncbi request reprint The prevalence of the metabolic syndrome did not increase in Mexico City between 1990-1992 and 1997-1999 despite more central obesity
    Carlos Lorenzo
    Department of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, Texas 78284 7873, USA
    Diabetes Care 28:2480-5. 2005
    ..We examined this hypothesis in the Mexico City Diabetes Study (MCDS), a study that showed rising trends in obesity, and the effect of the metabolic syndrome on the risk of coronary heart disease (CHD)...
  21. ncbi request reprint Trend in the prevalence of the metabolic syndrome and its impact on cardiovascular disease incidence: the San Antonio Heart Study
    Carlos Lorenzo
    Department of Medicine, Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284 7873, USA
    Diabetes Care 29:625-30. 2006
    ..Therefore, in the San Antonio Heart Study, a population-based study with worsening obesity, we examined the metabolic syndrome and its effect on incident cardiovascular disease (CVD)...
  22. ncbi request reprint Geographic variations of the International Diabetes Federation and the National Cholesterol Education Program-Adult Treatment Panel III definitions of the metabolic syndrome in nondiabetic subjects
    Carlos Lorenzo
    Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284 7873, USA
    Diabetes Care 29:685-91. 2006
    ..This analysis could help to discern the applicability of these definitions across populations...
  23. ncbi request reprint Is waist circumference an essential component of the metabolic syndrome?
    Carlos Lorenzo
    Department of Medicine, Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78284 7873, USA
    Diabetes Care 30:2141-2. 2007
  24. ncbi request reprint The National Cholesterol Education Program - Adult Treatment Panel III, International Diabetes Federation, and World Health Organization definitions of the metabolic syndrome as predictors of incident cardiovascular disease and diabetes
    Carlos Lorenzo
    Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78284 7873, USA
    Diabetes Care 30:8-13. 2007
    ....
  25. ncbi request reprint Which obesity index best explains prevalence differences in type 2 diabetes mellitus?
    Carlos Lorenzo
    Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284 7873, USA
    Obesity (Silver Spring) 15:1294-301. 2007
    ..Obesity drives the diabetes epidemic. However, it is not known which obesity index best explains variations in type 2 diabetes mellitus prevalence across populations...
  26. pmc Relation of low glomerular filtration rate to metabolic disorders in individuals without diabetes and with normoalbuminuria
    Carlos Lorenzo
    Department of Medicine, Division of Clinical Epidemiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78284 7873, USA
    Clin J Am Soc Nephrol 3:783-9. 2008
    ..Low glomerular filtration rate is also associated with increased cardiovascular risk, but the relation of low glomerular filtration rate to metabolic disorders is not well understood...
  27. ncbi request reprint The metabolic syndrome as predictor of type 2 diabetes: the San Antonio heart study
    Carlos Lorenzo
    Division of Clinical Epidemiology, University of Texas Health Science Center, San Antonio, Texas 78284 7873, USA
    Diabetes Care 26:3153-9. 2003
    ....
  28. ncbi request reprint NMR identifies atherogenic lipoprotein abnormalities in early diabetic nephropathy that are unrecognized by conventional analysis
    H Z Al-Shahrouri
    Division of Clinical Nephrology Department of Medicine, University of Texas Health Science Center, San Antonio, TX, USA
    Clin Nephrol 73:180-9. 2010
    ..The aim of this study was to investigate the relationship between lipoproteins and early manifestations of CKD in the 517 Type 2 diabetes mellitus (T2DM) patients who participated in the Insulin Resistance Atherosclerosis Study (IRAS)...
  29. pmc Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program
    Allan F Moore
    Center for Human Genetic Research, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
    Diabetes 57:2503-10. 2008
    ....
  30. pmc Is prehypertension a risk factor for the development of type 2 diabetes?
    David R Mullican
    Department of Medicine, Division of Clinical Epidemiology, University of Texas Health Science Center San Antonio, San Antonio, Texas
    Diabetes Care 32:1870-2. 2009
    ..However, whether subjects with prehypertension have more diabetes risk is not known. We examine whether prehypertension is a risk factor for developing type 2 diabetes...
  31. ncbi request reprint Early Pleistocene "hominid remains" from southern Spain and the taxonomic assignment of the Cueva Victoria phalanx
    Bienvenido Martinez-Navarro
    J Hum Evol 48:517-23. 2005
  32. ncbi request reprint Ethological study of manual laterality in naturalistic housed chimpanzees (Pan troglodytes) from the Mona Foundation Sanctuary (Girona, Spain)
    Marina Mosquera
    Grup d Autoecologia Humana, Area de Prehistoria, Facultat de Lletres, Universitat Rovira i Virgili, Tarragona, Spain
    Laterality 12:19-30. 2007
    ..So, laterality may not be influenced by humanisation. However, this conclusion must be taken as preliminary because very few individuals were studied...