James D Lord

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Refractory colitis following anti-CTLA4 antibody therapy: analysis of mucosal FOXP3+ T cells
    James D Lord
    Department of Medicine, University of Washington, Seattle, WA, USA
    Dig Dis Sci 55:1396-405. 2010
  2. pmc Blood and gastric FOXP3+ T cells are not decreased in human gastric graft-versus-host disease
    James D Lord
    Department of Medicine, University of Washington School of Medicine, Seattle, WA 98101, USA
    Biol Blood Marrow Transplant 17:486-96. 2011
  3. ncbi request reprint A case of fatal idiopathic enteritis and multiple opportunistic infections associated with dendritic cell deficiencies
    James D Lord
    Translational Research Program Benaroya Research Institute, Seattle, WA 98101 2795, USA
    J Gastrointestin Liver Dis 22:87-91. 2013
  4. pmc Paradoxically increased FOXP3+ T cells in IBD do not preferentially express the isoform of FOXP3 lacking exon 2
    James D Lord
    Translational Research Program, Benaroya Research Institute, Mailstop IN RC, 1201 Ninth Ave, Seattle, WA 98101 2795, USA
    Dig Dis Sci 57:2846-55. 2012

Detail Information

Publications4

  1. pmc Refractory colitis following anti-CTLA4 antibody therapy: analysis of mucosal FOXP3+ T cells
    James D Lord
    Department of Medicine, University of Washington, Seattle, WA, USA
    Dig Dis Sci 55:1396-405. 2010
    ..However, we found no evidence of FOXP3(+) T cell depletion in any of the nine patients who developed colitis...
  2. pmc Blood and gastric FOXP3+ T cells are not decreased in human gastric graft-versus-host disease
    James D Lord
    Department of Medicine, University of Washington School of Medicine, Seattle, WA 98101, USA
    Biol Blood Marrow Transplant 17:486-96. 2011
    ..There was no correlation of Treg frequency with the histologic or clinical severity of gastrointestinal GVHD. We conclude that Treg depletion is not a central feature in the pathogenesis of gastric GVHD in humans...
  3. ncbi request reprint A case of fatal idiopathic enteritis and multiple opportunistic infections associated with dendritic cell deficiencies
    James D Lord
    Translational Research Program Benaroya Research Institute, Seattle, WA 98101 2795, USA
    J Gastrointestin Liver Dis 22:87-91. 2013
    ..While the cause of her lack of DCs is unknown, this data suggests a key role for these cells in both regulating mucosal immunity and promoting effective cell-mediated immunity against pathogens in humans...
  4. pmc Paradoxically increased FOXP3+ T cells in IBD do not preferentially express the isoform of FOXP3 lacking exon 2
    James D Lord
    Translational Research Program, Benaroya Research Institute, Mailstop IN RC, 1201 Ninth Ave, Seattle, WA 98101 2795, USA
    Dig Dis Sci 57:2846-55. 2012
    ..FOXP3 inhibits IL-17A production, but a naturally occurring splice variant of FOXP3 lacking exon 2 (Δexon2) cannot...