E M Lord

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi request reprint Tumor immunotherapy: cytokines and antigen presentation
    E M Lord
    Department of Microbiology and Immunology, University of Rochester Medical Center, NY 14642, USA
    Cancer Immunol Immunother 46:75-81. 1998
  2. ncbi request reprint T-cell antigen discovery (T-CAD) assay: a novel technique for identifying T cell epitopes
    M J Turner
    Department of Microbiology and Immunology and the Cancer Center, University of Rochester Medical Center, Box 704, Rochester, NY 14642, USA
    J Immunol Methods 256:107-19. 2001
  3. pmc Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy
    C Wei
    Department of Microbiology and Immunology and the Cancer Center, University of Rochester Medical Center, Rochester, NY 14642, USA
    Proc Natl Acad Sci U S A 94:6369-74. 1997
  4. pmc Tumours can act as adjuvants for humoral immunity
    D M Brown
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Immunology 102:486-97. 2001
  5. ncbi request reprint Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice
    R A Willis
    Department of Microbiology and Immunology, University of Rochester, Rochester, NY 14642, USA
    Hum Gene Ther 12:1867-79. 2001
  6. pmc Alteration of tumour response to radiation by interleukin-2 gene transfer
    J Lee
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Br J Cancer 82:937-44. 2000
  7. pmc Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts
    S A Gerber
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Br J Cancer 88:1453-61. 2003

Collaborators

  • H J Federoff
  • J Lee
  • J G Frelinger
  • R A Willis
  • M J Turner
  • T L Fisher
  • S A Gerber
  • C Wei
  • C S Abdul-Alim
  • D M Brown
  • J P Moran
  • J A Frelinger
  • B M Fenton
  • D F Howard
  • W J Bowers
  • B R Tilton
  • R K Barth
  • R J Looney

Detail Information

Publications7

  1. ncbi request reprint Tumor immunotherapy: cytokines and antigen presentation
    E M Lord
    Department of Microbiology and Immunology, University of Rochester Medical Center, NY 14642, USA
    Cancer Immunol Immunother 46:75-81. 1998
    ..Despite recent advances, there is still much to be learned before the specificity of the immune system is safely harnessed to halt malignant cell growth effectively...
  2. ncbi request reprint T-cell antigen discovery (T-CAD) assay: a novel technique for identifying T cell epitopes
    M J Turner
    Department of Microbiology and Immunology and the Cancer Center, University of Rochester Medical Center, Box 704, Rochester, NY 14642, USA
    J Immunol Methods 256:107-19. 2001
    ..Additional characterization has shown that these peptides contribute significantly to the overall PSA specific response in vivo, and may represent the dominant epitopes of PSA...
  3. pmc Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy
    C Wei
    Department of Microbiology and Immunology and the Cancer Center, University of Rochester Medical Center, Rochester, NY 14642, USA
    Proc Natl Acad Sci U S A 94:6369-74. 1997
    ....
  4. pmc Tumours can act as adjuvants for humoral immunity
    D M Brown
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Immunology 102:486-97. 2001
    ..Furthermore, co-injection of both B16/OVA and line 1 tumours resulted in production of anti-OVA antibody, indicating that B16 tumours were not immunosuppressive, but instead line 1 tumours appear to exert an adjuvant effect...
  5. ncbi request reprint Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice
    R A Willis
    Department of Microbiology and Immunology, University of Rochester, Rochester, NY 14642, USA
    Hum Gene Ther 12:1867-79. 2001
    ..These results indicate that DCs transduced with HSV-1 amplicon vectors may provide a tool for investigation of the biology of CTL activation by DCs and a new modality for immunotherapy of cancer...
  6. pmc Alteration of tumour response to radiation by interleukin-2 gene transfer
    J Lee
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Br J Cancer 82:937-44. 2000
    ..These results indicate the potential therapeutic benefit of combining radiation and immunotherapy in the treatment of tumours...
  7. pmc Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts
    S A Gerber
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Br J Cancer 88:1453-61. 2003
    ..The combination of the whole mount technique and the GFP transgenic mice provides a powerful method for visualising tumour vasculature and characterising the effects of agents such as cytokines...