E M Lord

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Tumor immunotherapy: cytokines and antigen presentation
    E M Lord
    Department of Microbiology and Immunology, University of Rochester Medical Center, NY 14642, USA
    Cancer Immunol Immunother 46:75-81. 1998
  2. ncbi T-cell antigen discovery (T-CAD) assay: a novel technique for identifying T cell epitopes
    M J Turner
    Department of Microbiology and Immunology and the Cancer Center, University of Rochester Medical Center, Box 704, Rochester, NY 14642, USA
    J Immunol Methods 256:107-19. 2001
  3. ncbi Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy
    C Wei
    Department of Microbiology and Immunology and the Cancer Center, University of Rochester Medical Center, Rochester, NY 14642, USA
    Proc Natl Acad Sci U S A 94:6369-74. 1997
  4. ncbi Tumours can act as adjuvants for humoral immunity
    D M Brown
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Immunology 102:486-97. 2001
  5. ncbi Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice
    R A Willis
    Department of Microbiology and Immunology, University of Rochester, Rochester, NY 14642, USA
    Hum Gene Ther 12:1867-79. 2001
  6. ncbi Alteration of tumour response to radiation by interleukin-2 gene transfer
    J Lee
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Br J Cancer 82:937-44. 2000
  7. ncbi Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts
    S A Gerber
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Br J Cancer 88:1453-61. 2003

Collaborators

  • H J Federoff
  • J Lee
  • J G Frelinger
  • R A Willis
  • M J Turner
  • T L Fisher
  • S A Gerber
  • C Wei
  • D M Brown
  • C S Abdul-Alim
  • J P Moran
  • J A Frelinger
  • B M Fenton
  • W J Bowers
  • D F Howard
  • B R Tilton
  • R J Looney
  • R K Barth

Detail Information

Publications7

  1. ncbi Tumor immunotherapy: cytokines and antigen presentation
    E M Lord
    Department of Microbiology and Immunology, University of Rochester Medical Center, NY 14642, USA
    Cancer Immunol Immunother 46:75-81. 1998
    ..Despite recent advances, there is still much to be learned before the specificity of the immune system is safely harnessed to halt malignant cell growth effectively...
  2. ncbi T-cell antigen discovery (T-CAD) assay: a novel technique for identifying T cell epitopes
    M J Turner
    Department of Microbiology and Immunology and the Cancer Center, University of Rochester Medical Center, Box 704, Rochester, NY 14642, USA
    J Immunol Methods 256:107-19. 2001
    ..Additional characterization has shown that these peptides contribute significantly to the overall PSA specific response in vivo, and may represent the dominant epitopes of PSA...
  3. ncbi Tissue-specific expression of the human prostate-specific antigen gene in transgenic mice: implications for tolerance and immunotherapy
    C Wei
    Department of Microbiology and Immunology and the Cancer Center, University of Rochester Medical Center, Rochester, NY 14642, USA
    Proc Natl Acad Sci U S A 94:6369-74. 1997
    ....
  4. ncbi Tumours can act as adjuvants for humoral immunity
    D M Brown
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Immunology 102:486-97. 2001
    ..Furthermore, co-injection of both B16/OVA and line 1 tumours resulted in production of anti-OVA antibody, indicating that B16 tumours were not immunosuppressive, but instead line 1 tumours appear to exert an adjuvant effect...
  5. ncbi Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice
    R A Willis
    Department of Microbiology and Immunology, University of Rochester, Rochester, NY 14642, USA
    Hum Gene Ther 12:1867-79. 2001
    ..These results indicate that DCs transduced with HSV-1 amplicon vectors may provide a tool for investigation of the biology of CTL activation by DCs and a new modality for immunotherapy of cancer...
  6. ncbi Alteration of tumour response to radiation by interleukin-2 gene transfer
    J Lee
    Department of Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Br J Cancer 82:937-44. 2000
    ..These results indicate the potential therapeutic benefit of combining radiation and immunotherapy in the treatment of tumours...
  7. ncbi Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts
    S A Gerber
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Br J Cancer 88:1453-61. 2003
    ..The combination of the whole mount technique and the GFP transgenic mice provides a powerful method for visualising tumour vasculature and characterising the effects of agents such as cytokines...