Research Topics
| Catherine LordSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Regression and word loss in autistic spectrum disordersCatherine Lord
University of Michigan, Ann Arbor 48109 2054, USA
J Child Psychol Psychiatry 45:936-55. 2004....- Effects of self-esteem on age-related changes in cognition and the regulation of the hypothalamic-pituitary-adrenal axisJens C Pruessner
Douglas Hospital Research Center, FBC 1137, 6875 Boulevard LaSalle, Montreal QC H4H 1R3, Canada
Ann N Y Acad Sci 1032:186-90. 2004..It further suggests an effect on age-related endocrine changes in humans. These results are discussed with regard to potential mechanisms by which the reported association between self-esteem and aging could be mediated... - Early regression in social communication in autism spectrum disorders: a CPEA StudyRhiannon Luyster
Autism and Communication Disorders Center, University of Michigan, Ann Arbor 48109-2054, USA
Dev Neuropsychol 27:311-36. 2005..A significant minority of children with autism without word loss showed a very similar pattern of loss of social-communication skills, a pattern not observed in the children with developmental delays or typical development... - Challenges in evaluating psychosocial interventions for Autistic Spectrum DisordersCatherine Lord
University of Michigan, Austim and Communication Disorders Center 1111, Ann Arbor 48109, USA
J Autism Dev Disord 35:695-708; discussion 709-11. 2005.... - Autism from 2 to 9 years of ageCatherine Lord
University of Michigan Autism and Communication Disorders Center, Ann Arbor 48109, USA
Arch Gen Psychiatry 63:694-701. 2006..Autism represents an unusual pattern of development beginning in the infant and toddler years... 
The Autism Diagnostic Observation Schedule-toddler module: a new module of a standardized diagnostic measure for autism spectrum disordersRhiannon Luyster
University of Michigan Autism and Communication Disorders Center, Ann Arbor, MI, USA
J Autism Dev Disord 39:1305-20. 2009..The traditional algorithm "cutoffs" approach yielded high sensitivity and specificity, and a new range of concern approach was proposed...- Neural activation to emotional faces in adolescents with autism spectrum disordersShih Jen Weng
Department of Psychology, University of Michigan, USA Neuroscience Program, University of Michigan, USA
J Child Psychol Psychiatry 52:296-305. 2011.... - Patterns of growth in verbal abilities among children with autism spectrum disorderDeborah K Anderson
Autism and Communication Disorders Center, University of Michigan, Ann Arbor, MI 48109 2054, USA
J Consult Clin Psychol 75:594-604. 2007..Children with autism most at risk for more serious language impairments later in life can be identified with considerable accuracy at a very young age, while improvement can range from minimal to dramatic... - Is there a 'regressive phenotype' of Autism Spectrum Disorder associated with the measles-mumps-rubella vaccine? A CPEA StudyJennifer Richler
University of Michigan, Ann Arbor, 48109 2054, USA
J Autism Dev Disord 36:299-316. 2006..There was no evidence that onset of autistic symptoms or of regression was related to measles-mumps-rubella vaccination. The implications of these findings for the existence of a 'regressive phenotype' of ASD are discussed... - Alterations of resting state functional connectivity in the default network in adolescents with autism spectrum disordersShih Jen Weng
Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
Brain Res 1313:202-14. 2010..The findings also show that weaker connectivity within the default network is associated with specific impairments in ASD... - Neural circuitry of emotional face processing in autism spectrum disordersChristopher S Monk
Department of Psychology, University of Michigan, Ann Arbor, Mich 48109, USA
J Psychiatry Neurosci 35:105-14. 2010..Specifically, the cognitive domain of attention influences group differences in brain activation. We investigated brain function abnormalities in participants with ASD using a task that monitored attention bias to emotional faces... - The Autism Diagnostic Observation Schedule: revised algorithms for improved diagnostic validityKatherine Gotham
University of Michigan Autism and Communication Disorders Center, Ann Arbor, MI, 48109 2054, USA
J Autism Dev Disord 37:613-27. 2007.... - A replication of the Autism Diagnostic Observation Schedule (ADOS) revised algorithmsKatherine Gotham
University of Michigan Autism and Communication Disorders Center, 1111 East Catherine Street, Ann Arbor, MI 48109 2054, USA
J Am Acad Child Adolesc Psychiatry 47:642-51. 2008..To replicate the factor structure and predictive validity of revised Autism Diagnostic Observation Schedule algorithms in an independent dataset (N = 1,282)... - Using the autism diagnostic interview--revised to increase phenotypic homogeneity in genetic studies of autismVanessa Hus
University of Michigan Autism and Communication Disorders Center, Ann Arbor, Michigan, USA
Biol Psychiatry 61:438-48. 2007..Group differences in age, gender, IQ, and measures of autism severity are examined as related to Autism Diagnostic Interview-Revised (ADI-R) domains previously used for subsetting or Quantitative Trait Analysis (QTL)... - Word learning in children with autism spectrum disordersRhiannon Luyster
University of Michigan Autism and Communication Disorders Center, USA
Dev Psychol 45:1774-86. 2009..This result has important implications for understanding of how children with ASD learn language... - Restricted and repetitive behaviors in young children with autism spectrum disordersJennifer Richler
University of Michigan Autism and Communication Disorders Center, 1014 Church Street, Apt C4, Ann Arbor, MI, 48109, USA
J Autism Dev Disord 37:73-85. 2007..On average, children with ASD had more RSM behaviors. Behaviors that loaded on the IS factor were relatively uncommon and did not differ in prevalence or severity across groups... - Association between restricted and repetitive behaviors and nonverbal IQ in children with autism spectrum disordersSomer L Bishop
University of Michigan Autism and Communication Disorders Center, UMACC, 111 East Catherine Street, Ann Arbor, 48109, USA
Child Neuropsychol 12:247-67. 2006..For the severity of different RRBs, there were several significant effects for age and NVIQ, but few interactions... - Characterizing communicative development in children referred for autism spectrum disorders using the MacArthur-Bates Communicative Development Inventory (CDI)Rhiannon Luyster
University of Michigan Autism and Communication Disorders Center, Ann Arbor, MI 48109, USA
J Child Lang 34:623-54. 2007..However, when compared to published norms, children with ASD may show less of a discrepancy between their receptive and expressive vocabulary... - Patterns of growth in adaptive social abilities among children with autism spectrum disordersDeborah K Anderson
University of Michigan Autism and Communication Disorders Center, Ann Arbor, MI, 48109 2054, USA
J Abnorm Child Psychol 37:1019-34. 2009..Children with autism most at risk for problems with social adaptive abilities later in life can be identified with considerable accuracy at a very young age so they can be targeted for appropriate early intervention services... - Telescoping of caregiver report on the Autism Diagnostic Interview--RevisedVanessa Hus
University of Michigan Autism and Communication Disorders Center, USA
J Child Psychol Psychiatry 52:753-60. 2011..The current study examines the extent to which this phenomenon, referred to as 'telescoping,' impacts retrospective reports provided by caregivers of children with ASD... - Using a self-organizing map algorithm to detect age-related changes in functional connectivity during rest in autism spectrum disordersJillian Lee Wiggins
Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
Brain Res 1380:187-97. 2011..These findings indicate that SOM is a complementary method for calculating connectivity in a clinical population. Additionally, adolescents with ASD have a different developmental trajectory of the default network compared to controls... - Re-examining the core features of autism: a comparison of autism spectrum disorder and fetal alcohol spectrum disorderSomer Bishop
University of Michigan Autism and Communication Disorders Center, Ann Arbor 48109, USA
J Child Psychol Psychiatry 48:1111-21. 2007..Autism spectrum disorder (ASD) and fetal alcohol spectrum disorder (FASD) are both characterized by social difficulties, but overall clinical descriptions of the two disorders are different... - Standardizing ADOS scores for a measure of severity in autism spectrum disordersKatherine Gotham
University of Michigan Autism and Communication Disorders Center, Ann Arbor, MI 48109 2054, USA
J Autism Dev Disord 39:693-705. 2009..This metric should be useful in comparing assessments across modules and time, and identifying trajectories of autism severity for clinical, genetic, and neurobiological research... 
New autism diagnostic interview-revised algorithms for toddlers and young preschoolers from 12 to 47 months of ageSo Hyun Kim
University of Michigan Autism and Communication Disorders Center, 1111 Catherine St, Ann Arbor, MI 48109 2054, USA
J Autism Dev Disord 42:82-93. 2012..Using the new algorithms for toddlers and preschool children, we were able to improve sensitivity and specificity compared to the previously developed algorithm...- The autism spectrum: definitions, assessment and diagnosesCatherine Lord
University of Michigan Autism and Communication Disorders Center, Ann Arbor, Michigan 48109, USA
Br J Hosp Med (Lond) 70:132-5. 2009..This article summarizes current research related to autism spectrum disorders. Current epidemiological trends, theories about aetiology, and relevant issues in assessment and diagnosis of autism spectrum disorders are discussed... - Combining information from multiple sources in the diagnosis of autism spectrum disordersSusan Risi
University of Michigan Autism and Communication Disorders Center, Ann Arbor 48109 2054, USA
J Am Acad Child Adolesc Psychiatry 45:1094-103. 2006..Standard case criteria are proposed for combined use of the Autism Diagnostic Interview-Revised and Autism Diagnostic Observation Schedule to diagnose autism and to define the broader category of autism spectrum disorders... - Predicting outcomes of children referred for autism using the MacArthur-Bates Communicative Development InventoryRhiannon Luyster
University of Michigan Autism and Communication Disorders Center, 1111 East Catherine Street, Ann Arbor, MI 48109, USA
J Speech Lang Hear Res 50:667-81. 2007..This investigation explored whether scores on the MacArthur-Bates Communicative Development Inventory (CDI) at ages 2 and 3 years predict outcome at age 9 years in children with ASD and developmental delay (DD)... - Predictors of perceived negative impact in mothers of children with autism spectrum disorderSomer L Bishop
University of Michigan, Autism and Communication Disorders Center, Ann Arbor 48109, USA
Am J Ment Retard 112:450-61. 2007..Identifying predictors of perceived negative impact is an important first step in designing interventions to support families and target parents who may be at risk for experiencing higher levels of stress... - Changes in maladaptive behaviors from midchildhood to young adulthood in autism spectrum disorderDeborah K Anderson
University of Michigan, Ann Arbor, MI, USA
Am J Intellect Dev Disabil 116:381-97. 2011..Compared with youths without autism spectrum disorder, children with the disorder showed greater heterogeneity in trajectories for maladaptive behaviors... - Restricted and repetitive behaviors in toddlers and preschoolers with autism spectrum disorders based on the Autism Diagnostic Observation Schedule (ADOS)So Hyun Kim
University of Michigan Autism and Communication Disorders Center UMACC, Ann Arbor, Michigan 48109 2054, USA
Autism Res 3:162-73. 2010..These findings are discussed in terms of their implications for the etiology and treatment of RRBs as well as for the framework of ASD diagnostic criteria in future diagnostic systems... - Abnormalities of intrinsic functional connectivity in autism spectrum disordersChristopher S Monk
Department of Psychology, University of Michigan, 530 Church St, Ann Arbor MI 48109, USA
Neuroimage 47:764-72. 2009..These findings indicate that ASD subjects show altered intrinsic connectivity within the default network, and connectivity between these structures is associated with specific ASD symptoms... - Between a ROC and a hard place: decision making and making decisions about using the SCQChristina Corsello
University of California, San Diego, USA
J Child Psychol Psychiatry 48:932-40. 2007.... - Socio-communicative deficits in young children with Williams syndrome: performance on the Autism Diagnostic Observation ScheduleBonita P Klein-Tasman
Department of Psychology, University of Wisconsin Milwaukee, WI 53201, USA
Child Neuropsychol 13:444-67. 2007..Implications for our understanding of the socio-communicative abilities of young children with Williams syndrome and diagnostic practices regarding dual diagnosis are discussed... - Pre-linguistic Autism Diagnostic Observation Schedule adapted for older individuals with severe to profound mental retardation: a pilot studySibel Kazak Berument
Department of Psychology, Middle East Technical University, Ankara, Turkey
J Autism Dev Disord 35:821-9. 2005..Furthermore, the combination of codings into an overall algorithm score on social/communicative behavior resulted in a sensitivity of .82 and a specificity of .85 when using a cut-off score of 15... - Change in autism symptoms and maladaptive behaviors in adolescents and adults with an autism spectrum disorderPaul T Shattuck
University of Wisconsin, 533 Waisman Ctr, 1500 Highland Ave, Madison, WI 53705, USA
J Autism Dev Disord 37:1735-47. 2007..Compared to adolescents, older sample members (31 and older) had fewer maladaptive behaviors and experienced more improvement in these behaviors over time... - Reliability of the ADI-R: multiple examiners evaluate a single caseDomenic V Cicchetti
Child Study Center, Yale University School of Medicine, New Haven, CT, USA
J Autism Dev Disord 38:764-70. 2008..62 and 0.68); and in fair agreement on 3% (82 - 84%, with K(w) between .40 and .47). For the remaining 10% of ADI-R items, examiners showed poor agreement (50-81% with K(w )between -.67 and .37)... - Early indicators of autism spectrum disorders in the second year of lifeAmy M Wetherby
Department of Communication Disorders, Florida State University, Tallahassee, Florida, 32306 7814, USA
J Autism Dev Disord 34:473-93. 2004..These 13 red flags were found to discriminate the three groups with a correct classification rate of 94.4%... - The symptoms of autism spectrum disorders in adolescence and adulthoodMarsha Mailick Seltzer
Waisman Center, University of Wisconsin Madison, Madison, Wisconsin 53705 2280, USA
J Autism Dev Disord 33:565-81. 2003..Findings were interpreted in the context of life course development, reformulations of diagnostic criteria, and changing service contexts for individuals with autism spectrum disorders... - Early medical history of children with autism spectrum disordersRebecca Niehus
University of Michigan Autism and Communication Disorders Center University of Michigan, Ann Arbor, Michigan 48109, USA
J Dev Behav Pediatr 27:S120-7. 2006..Finally, pediatricians noted symptoms of onset of possible autism, including language delay, for 44 of the 75 children with ASD and 2 of the 24 typical children. Results are discussed in terms of needs for future research... - Social and communication abilities and disabilities in higher functioning individuals with autism spectrum disorders: the Vineland and the ADOSAmi Klin
Yale Child Study Center, Yale University School of Medicine, New Haven, CT 06520 7900, USA
J Autism Dev Disord 37:748-59. 2007..Positive relationships were found between IQ and Vineland Communication. Results stress the need for longitudinal studies on ability and disability in ASD and emphasize the importance of adaptive skills intervention... - 5-HTTLPR Genotype-Specific Phenotype in Children and Adolescents With AutismCamille W Brune
Institute for Juvenile Research, Department of Psychiatry M C 747, University of Illinois at Chicago, 1747 West Roosevelt Rd, Rm 155, Chicago, IL 60608, USA
Am J Psychiatry 163:2148-56. 2006..The heterogeneity in these reports may be due to clinical heterogeneity. The authors hypothesized that 5-HTTLPR genotypes would be related to variation in specific symptoms in children with autism... - Self-esteem, locus of control, hippocampal volume, and cortisol regulation in young and old adulthoodJens C Pruessner
McConnell Brain Imaging Center, Montreal Neurological Institute, Montreal, Quebec, Canada
Neuroimage 28:815-26. 2005.... - Genetics of childhood disorders: XLII. Autism, part 1: Diagnosis and assessment in autistic spectrum disordersCatherine Lord
University of Michigan Austism and Communication Disorders Center, Ann Arbor, USA
J Am Acad Child Adolesc Psychiatry 41:1134-6. 2002 - Cognitive profiles and social-communicative functioning in children with autism spectrum disorderRobert M Joseph
Department of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA
J Child Psychol Psychiatry 43:807-21. 2002.... - Social interaction behaviors discriminate young children with autism and Williams syndromeAlan J Lincoln
Alliant International University, 6160 Cornerstone Court E, San Diego, CA 92121, USA
J Am Acad Child Adolesc Psychiatry 46:323-31. 2007..We quantified the extent to which autism spectrum disorder (ASD) behaviors were present in children with WS... - Transmission disequilibrium studies of the serotonin 5-HT2A receptor gene (HTR2A) in autismJeremy Veenstra-Vanderweele
Laboratory of Developmental Neuroscience, Child and Adolescent Psychiatry, Department of Psychiatry, University of Chicago, Chicago, Illinois 60637, USA
Am J Med Genet 114:277-83. 2002..No evidence was found for unequal transmission of haplotypes; however, power analysis reveals low power to detect a parent-of-origin effect in this sample size... - Volumetry of temporopolar, perirhinal, entorhinal and parahippocampal cortex from high-resolution MR images: considering the variability of the collateral sulcusJens C Pruessner
McConnell Brain Imaging Center, Montreal Neurological Institute, Douglas Hospital Research Center, McGill University, Montreal, Quebec, Canada
Cereb Cortex 12:1342-53. 2002..Intra- and interrater coefficients are presented, together with mean values for the volumes of all PHG structures, correlations with age and sex, and tests for hemispheric differences... - Subject selection and characterization in clinical trials in children with autismLawrence Scahill
Department of Nursing, Child Study Center, Yale University at New Haven, CT 06520, USA
CNS Spectr 9:22-32. 2004.... - Autism and pervasive developmental disordersFred R Volkmar
Child Study Center, Yale University, New Haven, CT 06520, USA
J Child Psychol Psychiatry 45:135-70. 2004..Significant challenges lie ahead in evaluating the growing number of treatments for autism and in integrating the results of research into treatment and educational settings... - Outcome classification of preschool children with autism spectrum disorders using MRI brain measuresNatacha Akshoomoff
Children s Hospital Research Center, La Jolla, CA 92037, USA
J Am Acad Child Adolesc Psychiatry 43:349-57. 2004.... - Stress hormones and human memory function across the lifespanSonia J Lupien
Laboratory of Human Stress Research, Department of Psychiatry, Douglas Hospital Research Center, McGill University, 6875 Boudevard, LaSalle, Verdun, Que, Canada H4H 1R3
Psychoneuroendocrinology 30:225-42. 2005..Altogether, the results of these studies show that both bottom-up (effects of glucocorticoids on cognitive function), and top-down (effects of cognitive processing on glucocorticoid secretion) effects exist in the human population... - Hippocampal volumes are larger in postmenopausal women using estrogen therapy compared to past users, never users and men: a possible window of opportunity effectCatherine Lord
Center for Studies on Human Stress, Douglas Hospital Research Center, McGill University, 6875 Boul LaSalle, Verdun, Que H4H 1R3, Canada
Neurobiol Aging 29:95-101. 2008..The observed effects were region-specific since no significant differences could be observed for the AG. In summary, these findings support a treatment duration dependent neuroprotective role of estrogen on HC volume in aging... - Predictors of language acquisition in preschool children with autism spectrum disordersAudrey Thurm
Pediatric and Developmental Neuropsychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1255, USA
J Autism Dev Disord 37:1721-34. 2007.... - Designing research studies on psychosocial interventions in autismTristram Smith
Department of Pediatrics, Strong Center for Developmental Disabilities, University of Rochester Medical Center, 601 Elmwood, Box 671, Rochester, NY 14642, USA
J Autism Dev Disord 37:354-66. 2007.... - The developmental neurobiology of autism spectrum disorderEmanuel DiCicco-Bloom
Department of Neuroscience, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
J Neurosci 26:6897-906. 2006 - Mapping autism risk loci using genetic linkage and chromosomal rearrangementsPeter Szatmari
Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
Nat Genet 39:319-28. 2007..Neurexins team with previously implicated neuroligins for glutamatergic synaptogenesis, highlighting glutamate-related genes as promising candidates for contributing to ASDs... - Maternal care modulates the relationship between prenatal risk and hippocampal volume in women but not in menClaudia Buss
University of Trier, Department for Theoretical and Clinical Psychobiology, 54290 Trier, Germany
J Neurosci 27:2592-5. 2007..The results suggest that the postnatal environment modulates the neurodevelopmental consequences of prenatal risk and that this effect is sex-specific... - Association of the oxytocin receptor gene (OXTR) in Caucasian children and adolescents with autismSuma Jacob
Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, 1747 West Roosevelt Road, Chicago, IL 60608, USA
Neurosci Lett 417:6-9. 2007..Overtransmission of different alleles in different populations may be due to a different pattern of linkage disequilibrium between the marker rs2254298 and an as yet undetermined susceptibility variant in OXTR... - A unified genetic theory for sporadic and inherited autismXiaoyue Zhao
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA
Proc Natl Acad Sci U S A 104:12831-6. 2007.... - Familial autoimmune thyroid disease as a risk factor for regression in children with Autism Spectrum Disorder: a CPEA StudyCynthia A Molloy
Center for Epidemiology and Biostatistics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Ohio 45229 3039, USA
J Autism Dev Disord 36:317-24. 2006..89; 95% CI: 1.17, 3.10). The only specific autoimmune disorder found to be associated with regression was autoimmune thyroid disease (adjusted OR=2.09; 95% CI: 1.28, 3.41)... - Effects of manipulating the amount of social-evaluative threat on the cortisol stress response in young healthy menJulie Andrews
Centre for Studies on Human Stress, Douglas Mental Health Institute, McGill University, Montreal, PQ, Canada
Behav Neurosci 121:871-6. 2007..Future studies should include women and try to define the possible threshold to activate the HPA axis... - Mutation screening and transmission disequilibrium study of ATP10C in autismSoo-Jeong Kim
Laboratory of Developmental Neuroscience, Child and Adolescent Psychiatry, Department of Psychiatry MC3077, University of Chicago, Chicago, Illinois 60637, USA
Am J Med Genet 114:137-43. 2002.... - Depression during menopausal transition: a review of treatment strategies and pathophysiological correlatesBenicio N Frey
Women s Health Concerns Clinic WHCC, Department of Psychiatry and Behavioural Neurosciences, McMaster University, James Street South, FB 638, Hamilton, ON L8P 3B6, Canada
Menopause Int 14:123-8. 2008..The identification of individuals whom might be at a higher risk for depression during menopausal transition could guide preventive strategies for this population...
Research Grants
- 2/2-Effects of Parent-Implemented Intervention for Toddlers with Autism SpectrumCatherine Lord; Fiscal Year: 2009..Amy Wetherby at FSU and Dr. Catherine Lord at UM...
- 1/2 Development of a Screening Interview for Research Studies of ASDCatherine Lord; Fiscal Year: 2009....
- Longitudinal Studies of Autism Spectrum Disorders: 2 to 23Catherine Lord; Fiscal Year: 2010..This project will provide information that will be useful in developing new ways to improve quality of life for individuals with ASD and their families. ..
- 2/2-Effects of Parent-Implemented Intervention for Toddlers with Autism SpectrumCatherine Lord; Fiscal Year: 2010..Amy Wetherby at FSU and Dr. Catherine Lord at UM...
- 2/2-Effects of Parent-Implemented Intervention for Toddlers with Autism SpectrumCatherine Lord; Fiscal Year: 2009..Amy Wetherby at FSU and Dr. Catherine Lord at UM...
- Assessment Tool for Children's Impairments in Spontaneo*Catherine Lord; Fiscal Year: 2007..The tool will provide ways of measuring the severity of children's difficulties in language use that can be employed in studies of the relationship between various neurobiological factors. ..
- Validity of Diagnostic Measures for Autistic SpectrumCatherine Lord; Fiscal Year: 2006..In addition, the usefulness of a simpler, two domain plus language level approach to conceptualization of the autistic spectrum will be tested. ..
- Training/Research Diagnosis/Autistic Spectrum DisordersCatherine Lord; Fiscal Year: 2006..The addition of training specifically to train other trainers will enable more professionals to train research groups that are requesting training for newly funded or ongoing research projects. ..
- 1/2 Development of a Screening Interview for Research Studies of ASDCatherine Lord; Fiscal Year: 2010....