Sandra Loo

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Executive functioning among Finnish adolescents with attention-deficit/hyperactivity disorder
    Sandra K Loo
    University of California, Los Angeles, CA 90095, USA
    J Am Acad Child Adolesc Psychiatry 46:1594-604. 2007
  2. doi request reprint Characterization of the theta to beta ratio in ADHD: identifying potential sources of heterogeneity
    Sandra K Loo
    University of California Los Angeles, USA
    J Atten Disord 17:384-92. 2013
  3. pmc Clinical utility of EEG in attention-deficit/hyperactivity disorder: a research update
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA 90095, USA
    Neurotherapeutics 9:569-87. 2012
  4. doi request reprint Genome-wide association study of intelligence: additive effects of novel brain expressed genes
    Sandra K Loo
    University of California Los Angeles, 760 Westwood Plaza, Los Angeles, CA 90024, USA
    J Am Acad Child Adolesc Psychiatry 51:432-440.e2. 2012
  5. pmc Familial clustering and DRD4 effects on electroencephalogram measures in multiplex families with attention deficit/hyperactivity disorder
    Sandra K Loo
    Semel Institute for Neuroscience and Human Behavior and David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA
    J Am Acad Child Adolesc Psychiatry 49:368-77. 2010
  6. pmc Cortical activity patterns in ADHD during arousal, activation and sustained attention
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90024, United States
    Neuropsychologia 47:2114-9. 2009
  7. doi request reprint Cognitive functioning in affected sibling pairs with ADHD: familial clustering and dopamine genes
    Sandra K Loo
    UCLA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA, USA
    J Child Psychol Psychiatry 49:950-7. 2008
  8. ncbi request reprint Functional effects of the DAT1 polymorphism on EEG measures in ADHD
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, UCLA NPI, Los Angeles, USA
    J Am Acad Child Adolesc Psychiatry 42:986-93. 2003
  9. ncbi request reprint Preliminary report of familial clustering of EEG measures in ADHD
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, Semel Institute of Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
    Am J Med Genet B Neuropsychiatr Genet 147:107-9. 2008
  10. ncbi request reprint EEG correlates of methylphenidate response in ADHD: association with cognitive and behavioral measures
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, UCLA Neuropsychiatric Institute, Los Angeles, CA 90024, USA
    J Clin Neurophysiol 21:457-64. 2004

Research Grants

  1. Genetic Underpinnings of EEG Patterns in ADHD
    Sandra Loo; Fiscal Year: 2006
  2. Genetics of EEG Patterns in ADHD
    Sandra Loo; Fiscal Year: 2007
  3. Genetics of EEG Patterns in ADHD
    Sandra Loo; Fiscal Year: 2009
  4. Genetics of EEG Patterns in ADHD
    Sandra K Loo; Fiscal Year: 2010

Detail Information

Publications31

  1. ncbi request reprint Executive functioning among Finnish adolescents with attention-deficit/hyperactivity disorder
    Sandra K Loo
    University of California, Los Angeles, CA 90095, USA
    J Am Acad Child Adolesc Psychiatry 46:1594-604. 2007
    ..The present study examined cognitive functioning in a population sample of adolescents with and without attention-deficit/hyperactivity disorder (ADHD) from the Northern Finland Birth Cohort 1986...
  2. doi request reprint Characterization of the theta to beta ratio in ADHD: identifying potential sources of heterogeneity
    Sandra K Loo
    University of California Los Angeles, USA
    J Atten Disord 17:384-92. 2013
    ....
  3. pmc Clinical utility of EEG in attention-deficit/hyperactivity disorder: a research update
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA 90095, USA
    Neurotherapeutics 9:569-87. 2012
    ....
  4. doi request reprint Genome-wide association study of intelligence: additive effects of novel brain expressed genes
    Sandra K Loo
    University of California Los Angeles, 760 Westwood Plaza, Los Angeles, CA 90024, USA
    J Am Acad Child Adolesc Psychiatry 51:432-440.e2. 2012
    ..The purpose of the present study was to identify common genetic variants that are associated with human intelligence or general cognitive ability...
  5. pmc Familial clustering and DRD4 effects on electroencephalogram measures in multiplex families with attention deficit/hyperactivity disorder
    Sandra K Loo
    Semel Institute for Neuroscience and Human Behavior and David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA
    J Am Acad Child Adolesc Psychiatry 49:368-77. 2010
    ....
  6. pmc Cortical activity patterns in ADHD during arousal, activation and sustained attention
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90024, United States
    Neuropsychologia 47:2114-9. 2009
    ..The goal of the present study is to test whether there are Attention-Deficit Hyperactivity Disorder (ADHD)-related differences in brain electrical activity patterns across arousal, activation and vigilance states...
  7. doi request reprint Cognitive functioning in affected sibling pairs with ADHD: familial clustering and dopamine genes
    Sandra K Loo
    UCLA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA, USA
    J Child Psychol Psychiatry 49:950-7. 2008
    ..This paper examines familiality and candidate gene associations of cognitive measures as potential endophenotypes in attention-deficit/hyperactivity disorder (ADHD)...
  8. ncbi request reprint Functional effects of the DAT1 polymorphism on EEG measures in ADHD
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, UCLA NPI, Los Angeles, USA
    J Am Acad Child Adolesc Psychiatry 42:986-93. 2003
    ..This paper examines whether dopamine transporter gene (DAT1) allele status mediates medication-related change in cognitive and neurophysiological measures among children with attention-deficiency/hyperactivity disorder (ADHD)...
  9. ncbi request reprint Preliminary report of familial clustering of EEG measures in ADHD
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, Semel Institute of Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
    Am J Med Genet B Neuropsychiatr Genet 147:107-9. 2008
    ..Cognitive task performance did not exhibit familial clustering in our sample. EEG measures (i.e., alpha power) recorded during cognitive activation is a strongly familial trait in ADHD and may be a putative endophenotype for ADHD...
  10. ncbi request reprint EEG correlates of methylphenidate response in ADHD: association with cognitive and behavioral measures
    Sandra K Loo
    Department of Psychiatry and Biobehavioral Sciences, UCLA Neuropsychiatric Institute, Los Angeles, CA 90024, USA
    J Clin Neurophysiol 21:457-64. 2004
    ..Increased cortical arousal and activation in the frontal cortex is strongly associated with sustained attention and response inhibition and with parent-rated attention and hyperactivity/impulsivity...
  11. ncbi request reprint Clinical utility of EEG in attention deficit hyperactivity disorder
    Sandra K Loo
    UCLA Neuropsychiatric Institute, Los Angeles, California 90024, USA
    Appl Neuropsychol 12:64-76. 2005
    ....
  12. ncbi request reprint Genome-wide scan of reading ability in affected sibling pairs with attention-deficit/hyperactivity disorder: unique and shared genetic effects
    S K Loo
    Center for Neurobehavioral Genetics, University of California, Los Angeles, USA
    Mol Psychiatry 9:485-93. 2004
    ..The eventual identification of genes underlying these unique and shared linkages may increase our understanding of ADHD, RD and the relationship between the two...
  13. ncbi request reprint Psychiatric comorbidity in adult attention deficit hyperactivity disorder: findings from multiplex families
    James J McGough
    Center for Neurobehavioral Genetics, David Geffen School of Medicine, Suite 1414, 300 UCLA Medical Plaza, Los Angeles, CA 90095, USA
    Am J Psychiatry 162:1621-7. 2005
    ..Patterns of psychiatric comorbidity were assessed in adults with and without attention deficit hyperactivity disorder (ADHD) identified through a genetic study of families containing multiple children with ADHD...
  14. pmc Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder
    Ake T Lu
    Department of Human Genetics, University of California, Los Angeles, California, USA
    Am J Med Genet B Neuropsychiatr Genet 147:1488-94. 2008
    ..01 for C-G). These observations require replication, however, they suggest that the CNR1 gene may be a risk factor for ADHD and possibly PTSD, and that this gene warrants further investigation for a role in neuropsychiatric disorders...
  15. pmc Atypical alpha asymmetry in adults with ADHD
    T Sigi Hale
    Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience and Human Behavior, United States
    Neuropsychologia 47:2082-8. 2009
    ..The current study explores whether increased rightward alpha asymmetry is also evident in adults with ADHD...
  16. pmc ADHD familial loading and abnormal EEG alpha asymmetry in children with ADHD
    T Sigi Hale
    Division of Child and Adolescent Psychiatry and Center for Neurobehavioral Genetics at the UCLA Semel Institute, 760 Westwood Plaza, Room 47 448, Los Angeles, CA 90095, United States
    J Psychiatr Res 44:605-15. 2010
    ..Previous studies have shown increased rightward alpha asymmetry in ADHD. We tested whether this was more pronounced in ADHD children with increased ADHD family loading...
  17. pmc A candidate gene analysis of methylphenidate response in attention-deficit/hyperactivity disorder
    James J McGough
    Semel Institute for Neuroscience and Human Behavior and David Geffen School of Medicine, University of California, Los Angeles, USA
    J Am Acad Child Adolesc Psychiatry 48:1155-64. 2009
    ..This study examines the potential role of candidate genes in moderating treatment effects of methylphenidate (MPH) in attention-deficit/hyperactivity disorder (ADHD)...
  18. pmc CBCL pediatric bipolar disorder profile and ADHD: comorbidity and quantitative trait loci analysis
    James J McGough
    Division of Child and Adolescent Psychiatry, UCLA Semel Institute for Neuroscience and Human Behavior and David Geffen School of Medicine
    J Am Acad Child Adolesc Psychiatry 47:1151-7. 2008
    ..We used CBCL-PBD profiles to distinguish patterns of comorbidity and to search for quantitative trait loci in a genomewide scan in a sample of multiple affected ADHD sibling pairs...
  19. ncbi request reprint Toward localizing genes underlying cerebral asymmetry and mental health
    Susan L Smalley
    Center for Neurobehavioral Genetics, UCLA Neuropsychiatric Institute, David Geffen School of Medicine at UCLA, Los Angeles, California 90024, USA
    Am J Med Genet B Neuropsychiatr Genet 135:79-84. 2005
    ..Because ACA is associated with certain aspects of creativity, such risk genes may also be enhancer genes for creativity...
  20. pmc Rethinking a right hemisphere deficit in ADHD
    T Sigi Hale
    UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90024, USA
    J Atten Disord 13:3-17. 2009
    ..If true, RH pathology in ADHD should reflect interhemispherically networked and overactivated functioning. The authors evaluated these assertions...
  21. pmc Atypical EEG beta asymmetry in adults with ADHD
    T Sigi Hale
    Department of Psychiatry and Biobehavioral Sciences, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90024, USA
    Neuropsychologia 48:3532-9. 2010
    ..The current study investigates whether this ABL characteristic occurs in adults with ADHD absent comorbid language impairment...
  22. ncbi request reprint Prevalence and psychiatric comorbidity of attention-deficit/hyperactivity disorder in an adolescent Finnish population
    Susan L Smalley
    Semel Institute, University of California, Los Angeles, CA 90095, USA
    J Am Acad Child Adolesc Psychiatry 46:1575-83. 2007
    ..The purpose of the study was to estimate the prevalence of attention-deficit/hyperactivity disorder (ADHD) and its clinical characteristics in the Northern Finland Birth Cohort 1986...
  23. ncbi request reprint Familial association and frequency of learning disabilities in ADHD sibling pair families
    Melissa Del'Homme
    Department of Psychiatry and Biobehavioral Sciences, Semel Institute of Neuroscience and Human Behavior, University of California, 300 UCLA Medical Plaza, Suite 1416, Los Angeles, CA 90095 6967, USA
    J Abnorm Child Psychol 35:55-62. 2007
    ..Despite the high comorbidity of ADHD and LD among parents, the presence of ADHD in the parents did not predict child LD supporting independent familial factors underlying ADHD and LD...
  24. pmc Mindfulness and attention deficit hyperactivity disorder
    Susan L Smalley
    Mindful Awareness Research Center, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA 90095, USA
    J Clin Psychol 65:1087-98. 2009
    ..It further suggests that interventions that increase mindfulness might improve symptoms of ADHD and increase self-directedness and/or self-transcendence...
  25. pmc Social functioning difficulties in ADHD: association with PDD risk
    Erika Carpenter Rich
    Center for Neurobehavioral Genetics, University of California, Los Angeles, USA
    Clin Child Psychol Psychiatry 14:329-44. 2009
    ..51) than Peer Rejection (beta = .29) factors. Social Immaturity was also associated with a greater number of hyperactive symptoms while high Peer Rejection was associated with increased aggression and lower IQ in the ADHD children...
  26. ncbi request reprint Relationship of family environment and parental psychiatric diagnosis to impairment in ADHD
    Leah J Pressman
    Department of Psychiatry, UCLA Semel Institute, Los Angeles, CA 90095 1759, USA
    J Am Acad Child Adolesc Psychiatry 45:346-54. 2006
    ..The purpose of the present study was to examine the links among family environment, parental psychiatric diagnosis, and child impairment within a sample of ADHD-affected sibling pairs (ASPs) ages 5 to 18 years...
  27. ncbi request reprint Temperament and character profiles and the dopamine D4 receptor gene in ADHD
    Deborah E Lynn
    UCLA Department of Child and Adolescent Psychiatry, 10850 Wilshire Blvd, Suite 200, Los Angeles, CA 90024, USA
    Am J Psychiatry 162:906-13. 2005
    ..This study was designed to investigate the link among attention deficit hyperactivity disorder (ADHD) in adults, novelty-seeking temperament, and the 48-base pair (bp) dopamine D4 receptor (DRD4) gene variant...
  28. pmc Attention deficit hyperactivity disorder: fine mapping supports linkage to 5p13, 6q12, 16p13, and 17p11
    Matthew N Ogdie
    Human Genetics, University of California Los Angeles, Los Angeles, CA, USA
    Am J Hum Genet 75:661-8. 2004
    ..The refinement of linkage within each of these regions lays the foundation for subsequent investigations using association methods to detect risk genes of moderate effect size...
  29. ncbi request reprint ADHD symptoms and subtypes: relationship between childhood and adolescent symptoms
    Tuula Hurtig
    University of Oulu, Finland
    J Am Acad Child Adolesc Psychiatry 46:1605-13. 2007
    ..To study attention-deficit/hyperactivity disorder (ADHD) symptoms and DSM-IV subtypes in childhood and adolescence...
  30. ncbi request reprint Subtypes versus severity differences in attention-deficit/hyperactivity disorder in the Northern Finnish Birth Cohort
    Gitta H Lubke
    University of Notre Dame, Notre Dame, IN, USA
    J Am Acad Child Adolesc Psychiatry 46:1584-93. 2007
    ....
  31. ncbi request reprint ADHD candidate gene study in a population-based birth cohort: association with DBH and DRD2
    Emma S Nyman
    National Public Health Institute, Helsinki, Finland
    J Am Acad Child Adolesc Psychiatry 46:1614-21. 2007
    ..This study tests a series of allelic variants within such candidate genes to determine their potential influence on ADHD susceptibility...

Research Grants6

  1. Genetic Underpinnings of EEG Patterns in ADHD
    Sandra Loo; Fiscal Year: 2006
    ..Given the applicant's prior training, proposed mentorship, and outstanding resources, a K23 Award will enable her to become an independent and productive researcher in the genetics and developmental neuropsychology of ADHD. ..
  2. Genetics of EEG Patterns in ADHD
    Sandra Loo; Fiscal Year: 2007
    ..We are thus able to collect EEG data at a very low cost in a well characterized sample of ADHD ASPs upon which linkage studies (and candidate gene association work) are readily available. ..
  3. Genetics of EEG Patterns in ADHD
    Sandra Loo; Fiscal Year: 2009
    ..We are thus able to collect EEG data at a very low cost in a well characterized sample of ADHD ASPs upon which linkage studies (and candidate gene association work) are readily available. ..
  4. Genetics of EEG Patterns in ADHD
    Sandra K Loo; Fiscal Year: 2010
    ..We are thus able to collect EEG data at a very low cost in a well characterized sample of ADHD ASPs upon which linkage studies (and candidate gene association work) are readily available. ..