Sarah E London

Summary

Affiliation: University of Illinois
Country: USA

Publications

  1. pmc Functional identification of sensory mechanisms required for developmental song learning
    Sarah E London
    Institute for Genomic Biology, University of Illinois, Urbana Champaign, 2500N IGB, MC 195, 1206 West Gregory Drive, Urbana, Illinois 61801, USA
    Nat Neurosci 11:579-86. 2008
  2. pmc Developmental shifts in gene expression in the auditory forebrain during the sensitive period for song learning
    Sarah E London
    Institute for Genomic Biology, University of Illinois, Urbana Champaign Urbana, IL 61801, USA
    Dev Neurobiol 69:437-50. 2009
  3. pmc Widespread capacity for steroid synthesis in the avian brain and song system
    Sarah E London
    University of California, Los Angeles, 621 Charles Young Drive South, P O Box 951606, Los Angeles, California 90095 1606, USA
    Endocrinology 147:5975-87. 2006
  4. ncbi request reprint Steroidogenic enzymes along the ventricular proliferative zone in the developing songbird brain
    Sarah E London
    Interdepartmental Program in Neuroscience, Department of Physiological Science, Laboratory of Neuroendocrinology, University of California, Los Angeles, California 90095 1606, USA
    J Comp Neurol 502:507-21. 2007
  5. pmc Genomic and neural analysis of the estradiol-synthetic pathway in the zebra finch
    Sarah E London
    Institute for Genomic Biology, University of Illinois at Urbana Champaign, Urbana, IL, USA
    BMC Neurosci 11:46. 2010
  6. pmc Neural expression and post-transcriptional dosage compensation of the steroid metabolic enzyme 17beta-HSD type 4
    Sarah E London
    Interdepartmental Program in Neuroscience, University of California at Los Angeles, Los Angeles, CA, USA
    BMC Neurosci 11:47. 2010
  7. ncbi request reprint Cloning of the zebra finch androgen synthetic enzyme CYP17: a study of its neural expression throughout posthatch development
    Sarah E London
    Interdepartmental Graduate Program in Neuroscience, University of California Los Angeles, Los Angeles, California 90095, USA
    J Comp Neurol 467:496-508. 2003
  8. ncbi request reprint Neurosteroids and the songbird model system
    Barney A Schlinger
    Department of Physiological Science and Laboratory of Neuroendocrinology, Brain Research Institute, UCLA, Los Angeles, California 90095 1606, USA
    J Exp Zool A Comp Exp Biol 305:743-8. 2006
  9. pmc Birdsong and the neural production of steroids
    Luke Remage-Healey
    Department of Physiological Science and Ecology and Evolutionary Biology, Brain Research Institute, University of California, Los Angeles, CA 90095, United States
    J Chem Neuroanat 39:72-81. 2010
  10. ncbi request reprint Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction
    Ikuko Teramitsu
    Interdepartmental Programs in Molecular, Cellular, and Integrative Physiology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
    J Neurosci 24:3152-63. 2004

Research Grants

Collaborators

Detail Information

Publications14

  1. pmc Functional identification of sensory mechanisms required for developmental song learning
    Sarah E London
    Institute for Genomic Biology, University of Illinois, Urbana Champaign, 2500N IGB, MC 195, 1206 West Gregory Drive, Urbana, Illinois 61801, USA
    Nat Neurosci 11:579-86. 2008
    ..Thus the foundation of normal song learning, the formation of a sensory memory of tutor song, requires a conserved molecular pathway in a brain area that is distinct from the circuit for song motor control...
  2. pmc Developmental shifts in gene expression in the auditory forebrain during the sensitive period for song learning
    Sarah E London
    Institute for Genomic Biology, University of Illinois, Urbana Champaign Urbana, IL 61801, USA
    Dev Neurobiol 69:437-50. 2009
    ..Developmental gene expression changes may contribute to fine-tuning of cellular and molecular properties necessary for song learning...
  3. pmc Widespread capacity for steroid synthesis in the avian brain and song system
    Sarah E London
    University of California, Los Angeles, 621 Charles Young Drive South, P O Box 951606, Los Angeles, California 90095 1606, USA
    Endocrinology 147:5975-87. 2006
    ....
  4. ncbi request reprint Steroidogenic enzymes along the ventricular proliferative zone in the developing songbird brain
    Sarah E London
    Interdepartmental Program in Neuroscience, Department of Physiological Science, Laboratory of Neuroendocrinology, University of California, Los Angeles, California 90095 1606, USA
    J Comp Neurol 502:507-21. 2007
    ....
  5. pmc Genomic and neural analysis of the estradiol-synthetic pathway in the zebra finch
    Sarah E London
    Institute for Genomic Biology, University of Illinois at Urbana Champaign, Urbana, IL, USA
    BMC Neurosci 11:46. 2010
    ..Based on these analyses, we also investigated neural expression of a cholesterol transport protein gene in the context of song neurobiology...
  6. pmc Neural expression and post-transcriptional dosage compensation of the steroid metabolic enzyme 17beta-HSD type 4
    Sarah E London
    Interdepartmental Program in Neuroscience, University of California at Los Angeles, Los Angeles, CA, USA
    BMC Neurosci 11:47. 2010
    ..If a higher abundance of HSD17B4 mRNA in males than females was translated into functional enzyme in the brain, then contrary to expectation, males could produce less E2 in their brains than females...
  7. ncbi request reprint Cloning of the zebra finch androgen synthetic enzyme CYP17: a study of its neural expression throughout posthatch development
    Sarah E London
    Interdepartmental Graduate Program in Neuroscience, University of California Los Angeles, Los Angeles, California 90095, USA
    J Comp Neurol 467:496-508. 2003
    ..Our results support the hypothesis that neurosteroids may act to influence brain organization and function in the zebra finch...
  8. ncbi request reprint Neurosteroids and the songbird model system
    Barney A Schlinger
    Department of Physiological Science and Laboratory of Neuroendocrinology, Brain Research Institute, UCLA, Los Angeles, California 90095 1606, USA
    J Exp Zool A Comp Exp Biol 305:743-8. 2006
    ..We review the evidence published so far for songbird neurosteroidogenesis and discuss why we believe songbird species are excellent models for the study of brain steroid synthesis and action...
  9. pmc Birdsong and the neural production of steroids
    Luke Remage-Healey
    Department of Physiological Science and Ecology and Evolutionary Biology, Brain Research Institute, University of California, Los Angeles, CA 90095, United States
    J Chem Neuroanat 39:72-81. 2010
    ..Songbirds have therefore emerged as a rich and powerful model system to explore the neural and neurochemical regulation of social behavior...
  10. ncbi request reprint Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction
    Ikuko Teramitsu
    Interdepartmental Programs in Molecular, Cellular, and Integrative Physiology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
    J Neurosci 24:3152-63. 2004
    ..The specific colocalization of FoxP1 and FoxP2 found in several structures in the bird and human brain predicts that mutations in FOXP1 could also be related to speech disorders...
  11. pmc Integrating genomes, brain and behavior in the study of songbirds
    David F Clayton
    Institute for Genomic Biology, 1206 W Gregory Ave, University of Illinois, Urbana, IL 61801, USA
    Curr Biol 19:R865-73. 2009
    ..Access to the zebra finch genome sequence will, therefore, prompt new questions and provide the ability to answer those questions...
  12. pmc Impact of experience-dependent and -independent factors on gene expression in songbird brain
    Jenny Drnevich
    Carver Biotechnology Center and High Performance Biological Computing Group, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Proc Natl Acad Sci U S A 109:17245-52. 2012
    ..These results underscore the complexity of influences on neural gene expression and provide a resource for studying how these influences are integrated during natural experience...
  13. pmc Neurosteroid production in the songbird brain: a re-evaluation of core principles
    Sarah E London
    Institute for Genomic Biology, University of Illinois, Urbana Champaign, Urbana, IL 61801, USA
    Front Neuroendocrinol 30:302-14. 2009
    ..We hope this inspires further research and thought into neurosteroid signaling in songbirds and other animals...
  14. pmc RNA-seq transcriptome analysis of male and female zebra finch cell lines
    Christopher N Balakrishnan
    Department of Biology, East Carolina University, Greenville, NC 27858, USA
    Genomics 100:363-9. 2012
    ..These cell lines recapitulate fundamental songbird biology and will be useful for future studies of songbird gene regulation and function...

Research Grants2

  1. Developmental Differences in Brain Androgen Synthesis
    Sarah London; Fiscal Year: 2004
    ..They will also indicate potential regulatory mechanisms for androgen synthesis in other species, including humans. ..
  2. The molecular basis for developmental sensory learning
    Sarah London; Fiscal Year: 2008
    ..Thus, the study of sensory learning of tutor song in songbirds provides important insights into auditory mechanisms underlying human language acquisition. ..