Sarah E London
Affiliation: University of Illinois
- Functional identification of sensory mechanisms required for developmental song learningSarah E London
Institute for Genomic Biology, University of Illinois, Urbana Champaign, 2500N IGB, MC 195, 1206 West Gregory Drive, Urbana, Illinois 61801, USA
Nat Neurosci 11:579-86. 2008..Thus the foundation of normal song learning, the formation of a sensory memory of tutor song, requires a conserved molecular pathway in a brain area that is distinct from the circuit for song motor control...
- Developmental shifts in gene expression in the auditory forebrain during the sensitive period for song learningSarah E London
Institute for Genomic Biology, University of Illinois, Urbana Champaign Urbana, IL 61801, USA
Dev Neurobiol 69:437-50. 2009..Developmental gene expression changes may contribute to fine-tuning of cellular and molecular properties necessary for song learning...
- Widespread capacity for steroid synthesis in the avian brain and song systemSarah E London
University of California, Los Angeles, 621 Charles Young Drive South, P O Box 951606, Los Angeles, California 90095 1606, USA
Endocrinology 147:5975-87. 2006....
- Steroidogenic enzymes along the ventricular proliferative zone in the developing songbird brainSarah E London
Interdepartmental Program in Neuroscience, Department of Physiological Science, Laboratory of Neuroendocrinology, University of California, Los Angeles, California 90095 1606, USA
J Comp Neurol 502:507-21. 2007....
- Genomic and neural analysis of the estradiol-synthetic pathway in the zebra finchSarah E London
Institute for Genomic Biology, University of Illinois at Urbana Champaign, Urbana, IL, USA
BMC Neurosci 11:46. 2010..Based on these analyses, we also investigated neural expression of a cholesterol transport protein gene in the context of song neurobiology...
- Neural expression and post-transcriptional dosage compensation of the steroid metabolic enzyme 17beta-HSD type 4Sarah E London
Interdepartmental Program in Neuroscience, University of California at Los Angeles, Los Angeles, CA, USA
BMC Neurosci 11:47. 2010..If a higher abundance of HSD17B4 mRNA in males than females was translated into functional enzyme in the brain, then contrary to expectation, males could produce less E2 in their brains than females...
- Cloning of the zebra finch androgen synthetic enzyme CYP17: a study of its neural expression throughout posthatch developmentSarah E London
Interdepartmental Graduate Program in Neuroscience, University of California Los Angeles, Los Angeles, California 90095, USA
J Comp Neurol 467:496-508. 2003..Our results support the hypothesis that neurosteroids may act to influence brain organization and function in the zebra finch...
- Neurosteroids and the songbird model systemBarney A Schlinger
Department of Physiological Science and Laboratory of Neuroendocrinology, Brain Research Institute, UCLA, Los Angeles, California 90095 1606, USA
J Exp Zool A Comp Exp Biol 305:743-8. 2006..We review the evidence published so far for songbird neurosteroidogenesis and discuss why we believe songbird species are excellent models for the study of brain steroid synthesis and action...
- Birdsong and the neural production of steroidsLuke Remage-Healey
Department of Physiological Science and Ecology and Evolutionary Biology, Brain Research Institute, University of California, Los Angeles, CA 90095, United States
J Chem Neuroanat 39:72-81. 2010..Songbirds have therefore emerged as a rich and powerful model system to explore the neural and neurochemical regulation of social behavior...
- Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interactionIkuko Teramitsu
Interdepartmental Programs in Molecular, Cellular, and Integrative Physiology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
J Neurosci 24:3152-63. 2004..The specific colocalization of FoxP1 and FoxP2 found in several structures in the bird and human brain predicts that mutations in FOXP1 could also be related to speech disorders...
- Integrating genomes, brain and behavior in the study of songbirdsDavid F Clayton
Institute for Genomic Biology, 1206 W Gregory Ave, University of Illinois, Urbana, IL 61801, USA
Curr Biol 19:R865-73. 2009..Access to the zebra finch genome sequence will, therefore, prompt new questions and provide the ability to answer those questions...
- Impact of experience-dependent and -independent factors on gene expression in songbird brainJenny Drnevich
Carver Biotechnology Center and High Performance Biological Computing Group, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Proc Natl Acad Sci U S A 109:17245-52. 2012..These results underscore the complexity of influences on neural gene expression and provide a resource for studying how these influences are integrated during natural experience...
- Neurosteroid production in the songbird brain: a re-evaluation of core principlesSarah E London
Institute for Genomic Biology, University of Illinois, Urbana Champaign, Urbana, IL 61801, USA
Front Neuroendocrinol 30:302-14. 2009..We hope this inspires further research and thought into neurosteroid signaling in songbirds and other animals...
- RNA-seq transcriptome analysis of male and female zebra finch cell linesChristopher N Balakrishnan
Department of Biology, East Carolina University, Greenville, NC 27858, USA
Genomics 100:363-9. 2012..These cell lines recapitulate fundamental songbird biology and will be useful for future studies of songbird gene regulation and function...
- Developmental Differences in Brain Androgen SynthesisSarah London; Fiscal Year: 2004..They will also indicate potential regulatory mechanisms for androgen synthesis in other species, including humans. ..
- The molecular basis for developmental sensory learningSarah London; Fiscal Year: 2008..Thus, the study of sensory learning of tutor song in songbirds provides important insights into auditory mechanisms underlying human language acquisition. ..