Vedang A Londhe

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Retinoic acid rescues alveolar hypoplasia in the calorie-restricted developing rat lung
    Vedang A Londhe
    Neonatal Research Center, Division of Neonatology and Developmental Biology, Department of Pediatrics, David Geffen School of Medicine, University of California at Los Angeles, 10833 Le Conte Ave, Mailcode 175217, B2 375 MDCC, Los Angeles, CA 90095 1752, USA
    Am J Respir Cell Mol Biol 48:179-87. 2013
  2. pmc Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis
    Vedang A Londhe
    Department of Pediatrics, Division of Neonatology and Developmental Biology, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Mailcode 175217, Los Angeles, CA, USA
    Respir Res 12:134. 2011
  3. pmc Hyperoxia impairs alveolar formation and induces senescence through decreased histone deacetylase activity and up-regulation of p21 in neonatal mouse lung
    Vedang A Londhe
    Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Pediatr Res 69:371-7. 2011
  4. pmc A subset of epithelial cells with CCSP promoter activity participates in alveolar development
    Vedang A Londhe
    Department of Pediatrics, Division of Neonatology and Developmental Biology, Neonatal Research Center, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California 90095 1752, USA
    Am J Respir Cell Mol Biol 44:804-12. 2011
  5. ncbi request reprint NF-kB induces lung maturation during mouse lung morphogenesis
    Vedang A Londhe
    Department of Pediatrics, Division of Neonatology and Developmental Biology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 1752, USA
    Dev Dyn 237:328-38. 2008
  6. pmc TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells
    Nian Ling Zhu
    University of Southern California, Keck School of Medicine, Department of Pediatrics, Division of Neonatal Medicine, Los Angeles, CA 90033, United States
    Gene 393:70-80. 2007
  7. ncbi request reprint Developmental pathways and specification of intrapulmonary stem cells
    Zea Borok
    Department of Medicine, Will Rogers Institute Pulmonary Research Center, University of Southern California, Los Angeles, 90033, USA
    Pediatr Res 59:84R-93R. 2006
  8. pmc Vitamin A supplementation in extremely low-birth-weight infants: subgroup analysis in small-for-gestational-age infants
    Vedang A Londhe
    Division of Neonatology and Developmental Biology, Department of Pediatrics, Neonatal Research Center, David Geffen School of Medicine at UCLA, Los Angeles, California
    Am J Perinatol 30:771-80. 2013
  9. pmc Caffeine induces alveolar apoptosis in the hyperoxia-exposed developing mouse lung
    Sara Dayanim
    Department of Pediatrics, Division of Neonatology and Developmental Biology, David Geffen School of Medicine, Neonatal Research Center, University of California, Los Angeles, California
    Pediatr Res 75:395-402. 2014

Research Grants

Collaborators

Detail Information

Publications10

  1. pmc Retinoic acid rescues alveolar hypoplasia in the calorie-restricted developing rat lung
    Vedang A Londhe
    Neonatal Research Center, Division of Neonatology and Developmental Biology, Department of Pediatrics, David Geffen School of Medicine, University of California at Los Angeles, 10833 Le Conte Ave, Mailcode 175217, B2 375 MDCC, Los Angeles, CA 90095 1752, USA
    Am J Respir Cell Mol Biol 48:179-87. 2013
    ....
  2. pmc Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis
    Vedang A Londhe
    Department of Pediatrics, Division of Neonatology and Developmental Biology, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Mailcode 175217, Los Angeles, CA, USA
    Respir Res 12:134. 2011
    ..The purpose of this study was to test our hypothesis that targeted deletion of NF-κB signaling in lung epithelium would impair alveolar formation...
  3. pmc Hyperoxia impairs alveolar formation and induces senescence through decreased histone deacetylase activity and up-regulation of p21 in neonatal mouse lung
    Vedang A Londhe
    Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Pediatr Res 69:371-7. 2011
    ..These findings suggest that alveolar hypoplasia caused by hyperoxia is mediated by epigenetic changes affecting cell cycle regulation/senescence during lung development...
  4. pmc A subset of epithelial cells with CCSP promoter activity participates in alveolar development
    Vedang A Londhe
    Department of Pediatrics, Division of Neonatology and Developmental Biology, Neonatal Research Center, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California 90095 1752, USA
    Am J Respir Cell Mol Biol 44:804-12. 2011
    ..These findings are consistent with a model in which a unique population of cells with CCSP promoter activity that expresses vascular endothelial growth factor participates in alveolar development...
  5. ncbi request reprint NF-kB induces lung maturation during mouse lung morphogenesis
    Vedang A Londhe
    Department of Pediatrics, Division of Neonatology and Developmental Biology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 1752, USA
    Dev Dyn 237:328-38. 2008
    ..These findings are consistent with a model whereby NF-kB may induce maturation of lung development through decreased apoptosis of epithelial cells...
  6. pmc TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells
    Nian Ling Zhu
    University of Southern California, Keck School of Medicine, Department of Pediatrics, Division of Neonatal Medicine, Los Angeles, CA 90033, United States
    Gene 393:70-80. 2007
    ..These findings provide a mechanistic paradigm for interactions between mediators of inflammation and morphogenesis with relevant implications for normal lung development and pathogenesis of disease...
  7. ncbi request reprint Developmental pathways and specification of intrapulmonary stem cells
    Zea Borok
    Department of Medicine, Will Rogers Institute Pulmonary Research Center, University of Southern California, Los Angeles, 90033, USA
    Pediatr Res 59:84R-93R. 2006
    ....
  8. pmc Vitamin A supplementation in extremely low-birth-weight infants: subgroup analysis in small-for-gestational-age infants
    Vedang A Londhe
    Division of Neonatology and Developmental Biology, Department of Pediatrics, Neonatal Research Center, David Geffen School of Medicine at UCLA, Los Angeles, California
    Am J Perinatol 30:771-80. 2013
    ....
  9. pmc Caffeine induces alveolar apoptosis in the hyperoxia-exposed developing mouse lung
    Sara Dayanim
    Department of Pediatrics, Division of Neonatology and Developmental Biology, David Geffen School of Medicine, Neonatal Research Center, University of California, Los Angeles, California
    Pediatr Res 75:395-402. 2014
    ..Utilizing a well-characterized newborn mouse model of alveolar hypoplasia, we hypothesized that hyperoxia-induced alveolar inflammation and hypoplasia is associated with alterations in the adenosine signaling pathway...

Research Grants2

  1. Inflammatory and Chemotactic Cytokines in Bronchopulmonary Dysplasia
    Vedang Londhe; Fiscal Year: 2007
    ..End of Abstract) ..