Catherine Lomen-Hoerth

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease
    Sruti Rayaprolu
    Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
    Mol Neurodegener 8:19. 2013
  2. doi request reprint Amyotrophic lateral sclerosis from bench to bedside
    Catherine Lomen-Hoerth
    Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, Suite 500, San Francisco, CA 94117, USA
    Semin Neurol 28:205-11. 2008
  3. doi request reprint Clinical phenomenology and neuroimaging correlates in ALS-FTD
    Catherine Lomen-Hoerth
    Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, Suite 500, San Francisco, CA 94117, USA
    J Mol Neurosci 45:656-62. 2011
  4. pmc Cognitive and behavioral challenges in caring for patients with frontotemporal dementia and amyotrophic lateral sclerosis
    Jennifer Merrilees
    University of California, San Francisco, USA
    Amyotroph Lateral Scler 11:298-302. 2010
  5. pmc Deciphering amyotrophic lateral sclerosis: what phenotype, neuropathology and genetics are telling us about pathogenesis
    John Ravits
    Department of Neurosciences, University of California, San Diego, La Jolla, California 92093, USA
    Amyotroph Lateral Scler Frontotemporal Degener 14:5-18. 2013
  6. pmc Behaviour, physiology and experience of pathological laughing and crying in amyotrophic lateral sclerosis
    Nicholas T Olney
    UCSF School of Medicine, San Francisco, CA 94143 1207, USA
    Brain 134:3458-69. 2011
  7. ncbi request reprint 17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions
    Kirk C Wilhelmsen
    Ernest Gallo Clinic and Research Center, Emeryville, CA, USA
    Arch Neurol 61:398-406. 2004
  8. ncbi request reprint Characterization of amyotrophic lateral sclerosis and frontotemporal dementia
    Catherine Lomen-Hoerth
    University of California, San Francisco, Calif, USA
    Dement Geriatr Cogn Disord 17:337-41. 2004
  9. ncbi request reprint Establishing subtypes of the continuum of frontal lobe impairment in amyotrophic lateral sclerosis
    Jennifer Murphy
    ALS Center, University of California at San Francisco, 350 Parnassus Ave, Suite 500, San Francisco, CA 94117, USA
    Arch Neurol 64:330-4. 2007
  10. ncbi request reprint Continuum of frontal lobe impairment in amyotrophic lateral sclerosis
    Jennifer M Murphy
    Department of Neurology, ALS Center, University of California, San Francisco, CA 94117, USA
    Arch Neurol 64:530-4. 2007

Detail Information

Publications23

  1. pmc TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease
    Sruti Rayaprolu
    Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
    Mol Neurodegener 8:19. 2013
    ..With this in mind we set out to assess the genetic association of the Alzheimer's disease-related risk variant in TREM2 (rs75932628, p.R47H) with other related neurodegenerative disorders...
  2. doi request reprint Amyotrophic lateral sclerosis from bench to bedside
    Catherine Lomen-Hoerth
    Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, Suite 500, San Francisco, CA 94117, USA
    Semin Neurol 28:205-11. 2008
    ..Overlap with dementia may provide new clues to the etiology and treatment. There have been many advances in symptomatic treatments and improvements in the quality of life for ALS patients due to technological advancements...
  3. doi request reprint Clinical phenomenology and neuroimaging correlates in ALS-FTD
    Catherine Lomen-Hoerth
    Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, Suite 500, San Francisco, CA 94117, USA
    J Mol Neurosci 45:656-62. 2011
    ..Identification of the overlap syndrome also provides a unique opportunity to study very early signs of FTD and conversely, very early signs of ALS, to gain greater insight into both disorders...
  4. pmc Cognitive and behavioral challenges in caring for patients with frontotemporal dementia and amyotrophic lateral sclerosis
    Jennifer Merrilees
    University of California, San Francisco, USA
    Amyotroph Lateral Scler 11:298-302. 2010
    ..This paper provides a guide for healthcare providers caring for patients with FTD-ALS exhibiting behavioral, cognitive, and emotional symptoms. Strategies are suggested to help minimize the impact of negative symptoms...
  5. pmc Deciphering amyotrophic lateral sclerosis: what phenotype, neuropathology and genetics are telling us about pathogenesis
    John Ravits
    Department of Neurosciences, University of California, San Diego, La Jolla, California 92093, USA
    Amyotroph Lateral Scler Frontotemporal Degener 14:5-18. 2013
    ..If fundamental mechanisms could be identified and understood, ALS therapy could rationally target progression and stop the disease - a goal that seems increasingly achievable...
  6. pmc Behaviour, physiology and experience of pathological laughing and crying in amyotrophic lateral sclerosis
    Nicholas T Olney
    UCSF School of Medicine, San Francisco, CA 94143 1207, USA
    Brain 134:3458-69. 2011
    ....
  7. ncbi request reprint 17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusions
    Kirk C Wilhelmsen
    Ernest Gallo Clinic and Research Center, Emeryville, CA, USA
    Arch Neurol 61:398-406. 2004
    ..The most common familial form of this condition is caused by mutations in the microtubule-associated protein tau gene (MAP tau) and is associated with neuronal or glial tau inclusions...
  8. ncbi request reprint Characterization of amyotrophic lateral sclerosis and frontotemporal dementia
    Catherine Lomen-Hoerth
    University of California, San Francisco, Calif, USA
    Dement Geriatr Cogn Disord 17:337-41. 2004
    ..We report the features of cognitive impairment and pattern of motor involvement in these ALS-FTD patients, and the degree of overlap in both populations...
  9. ncbi request reprint Establishing subtypes of the continuum of frontal lobe impairment in amyotrophic lateral sclerosis
    Jennifer Murphy
    ALS Center, University of California at San Francisco, 350 Parnassus Ave, Suite 500, San Francisco, CA 94117, USA
    Arch Neurol 64:330-4. 2007
    ..As more investigations use standardized tools measuring behavior and cognition, distinct subtypes may be diagnosed...
  10. ncbi request reprint Continuum of frontal lobe impairment in amyotrophic lateral sclerosis
    Jennifer M Murphy
    Department of Neurology, ALS Center, University of California, San Francisco, CA 94117, USA
    Arch Neurol 64:530-4. 2007
    ..To identify the nature and prevalence of cognitive and behavioral abnormalities in patients with amyotrophic lateral sclerosis (ALS)...
  11. ncbi request reprint Dysphagia in patients with frontotemporal lobar dementia
    Susan E Langmore
    Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, 94115, USA
    Arch Neurol 64:58-62. 2007
    ..Hyperorality, compulsive eating and aspiration because of food gorging, has been described in patients with frontotemporal lobar dementia (FTLD), but swallowing function in this population has not been reported...
  12. pmc Frontotemporal dementia in a Brazilian kindred with the c9orf72 mutation
    Leonel T Takada
    Memory and AgingCenter, University of California, San Francisco, 350 Parnassus Ave, Ste 905, San Francisco, CA 94143 1207, USA
    Arch Neurol 69:1149-53. 2012
    ....
  13. pmc Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions
    Eric J Huang
    Department of Pathology, University of California, San Francisco, CA, USA
    Brain Pathol 20:1069-76. 2010
    ..Furthermore, our study represents the first detailed characterizations of neuropathological findings in rapidly progressive juvenile ALS patients with a mutation in the FUS/TLS gene...
  14. doi request reprint Organ donation after cardiac death in amyotrophic lateral sclerosis
    Shahed Toossi
    Department of Neurology, University of California at San Francisco, USA
    Ann Neurol 71:154-6. 2012
    ..To our knowledge, this is the first report of organ donation in a patient with rapidly progressive ventilator-dependent ALS...
  15. ncbi request reprint The overlap of amyotrophic lateral sclerosis and frontotemporal dementia
    Catherine Lomen-Hoerth
    University of California, San Francisco, 94143, USA
    Neurology 59:1077-9. 2002
    ..One of the patients with fasciculations and a normal EMG study progressed to definite ALS over the course of 1 year...
  16. ncbi request reprint Statistical motor unit number estimation: from theory to practice
    Catherine Lomen-Hoerth
    Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, Room M348, San Francisco, California 94143, USA
    Muscle Nerve 28:263-72. 2003
    ....
  17. pmc Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III
    Petra Kaufmann
    Department of Neurology, Clinical Coordinating Center, Columbia University, New York, NY 10032, USA
    Ann Neurol 66:235-44. 2009
    ..Our aims were to choose between two high doses of CoQ10 for ALS, and to determine if it merits testing in a Phase III clinical trial...
  18. doi request reprint Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affect
    Erik P Pioro
    Section of ALS and Related Disorders, Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Ann Neurol 68:693-702. 2010
    ..To evaluate dextromethorphan combined with ultra low-dose quinidine (DMq) for treating pseudobulbar affect (PBA) in patients with amyotrophic lateral sclerosis (ALS) or multiple sclerosis (MS)...
  19. ncbi request reprint Exit strategies in ALS: an influence of depression or despair?
    Richard K Olney
    Neurology 65:9-10. 2005
  20. ncbi request reprint Cognitive impairment, frontotemporal dementia, and the motor neuron diseases
    Michael J Strong
    Department of Clinical Neurological Sciences and the Robarts Research Institute, London, Ontario, Canada
    Ann Neurol 54:S20-3. 2003
  21. ncbi request reprint Whole-genome analysis of sporadic amyotrophic lateral sclerosis
    Travis Dunckley
    Translational Genomics Research Inst, Phoenix, AZ 85004, USA
    N Engl J Med 357:775-88. 2007
    ..Approximately 90% of persons with amyotrophic lateral sclerosis (ALS) have the sporadic form, which may be caused by the interaction of multiple environmental factors and previously unknown genes...
  22. ncbi request reprint ALS treatment strikes out while trying for a homer: the topiramate trial
    Petra Kaufmann
    Neurology 61:434-5. 2003
  23. pmc Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery
    Katrina Gwinn
    National Institute for Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 2:e1254. 2007
    ..This resource should facilitate genetic discoveries which we anticipate will ultimately provide a better understanding of the biological mechanisms of neurodegeneration in ALS...