Research Topics
Species | Catherine Lomen-HoerthSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Amyotrophic lateral sclerosis from bench to bedsideCatherine Lomen-Hoerth
Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, Suite 500, San Francisco, CA 94117, USA
Semin Neurol 28:205-11. 2008..Overlap with dementia may provide new clues to the etiology and treatment. There have been many advances in symptomatic treatments and improvements in the quality of life for ALS patients due to technological advancements...
Clinical phenomenology and neuroimaging correlates in ALS-FTDCatherine Lomen-Hoerth
Department of Neurology, University of California, San Francisco, 350 Parnassus Avenue, Suite 500, San Francisco, CA 94117, USA
J Mol Neurosci 45:656-62. 2011..Identification of the overlap syndrome also provides a unique opportunity to study very early signs of FTD and conversely, very early signs of ALS, to gain greater insight into both disorders...
Cognitive and behavioral challenges in caring for patients with frontotemporal dementia and amyotrophic lateral sclerosisJennifer Merrilees
University of California, San Francisco, USA
Amyotroph Lateral Scler 11:298-302. 2010..This paper provides a guide for healthcare providers caring for patients with FTD-ALS exhibiting behavioral, cognitive, and emotional symptoms. Strategies are suggested to help minimize the impact of negative symptoms...
Behaviour, physiology and experience of pathological laughing and crying in amyotrophic lateral sclerosisNicholas T Olney
UCSF School of Medicine, San Francisco, CA 94143 1207, USA
Brain 134:3458-69. 2011....
17q-linked frontotemporal dementia-amyotrophic lateral sclerosis without tau mutations with tau and alpha-synuclein inclusionsKirk C Wilhelmsen
Ernest Gallo Clinic and Research Center, Emeryville, CA, USA
Arch Neurol 61:398-406. 2004..The most common familial form of this condition is caused by mutations in the microtubule-associated protein tau gene (MAP tau) and is associated with neuronal or glial tau inclusions...
Characterization of amyotrophic lateral sclerosis and frontotemporal dementiaCatherine Lomen-Hoerth
University of California, San Francisco, Calif, USA
Dement Geriatr Cogn Disord 17:337-41. 2004..We report the features of cognitive impairment and pattern of motor involvement in these ALS-FTD patients, and the degree of overlap in both populations...
Establishing subtypes of the continuum of frontal lobe impairment in amyotrophic lateral sclerosisJennifer Murphy
ALS Center, University of California at San Francisco, 350 Parnassus Ave, Suite 500, San Francisco, CA 94117, USA
Arch Neurol 64:330-4. 2007..As more investigations use standardized tools measuring behavior and cognition, distinct subtypes may be diagnosed...
Continuum of frontal lobe impairment in amyotrophic lateral sclerosisJennifer M Murphy
Department of Neurology, ALS Center, University of California, San Francisco, CA 94117, USA
Arch Neurol 64:530-4. 2007..To identify the nature and prevalence of cognitive and behavioral abnormalities in patients with amyotrophic lateral sclerosis (ALS)...
Dysphagia in patients with frontotemporal lobar dementiaSusan E Langmore
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, 94115, USA
Arch Neurol 64:58-62. 2007..Hyperorality, compulsive eating and aspiration because of food gorging, has been described in patients with frontotemporal lobar dementia (FTLD), but swallowing function in this population has not been reported...
Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusionsEric J Huang
Department of Pathology, University of California, San Francisco, CA, USA
Brain Pathol 20:1069-76. 2010..Furthermore, our study represents the first detailed characterizations of neuropathological findings in rapidly progressive juvenile ALS patients with a mutation in the FUS/TLS gene...
Frontotemporal dementia in a Brazilian kindred with the c9orf72 mutationLeonel T Takada
Memory and AgingCenter, University of California, San Francisco, 350 Parnassus Ave, Ste 905, San Francisco, CA 94143 1207, USA
Arch Neurol 69:1149-53. 2012....
Organ donation after cardiac death in amyotrophic lateral sclerosisShahed Toossi
Department of Neurology, University of California at San Francisco, USA
Ann Neurol 71:154-6. 2012..To our knowledge, this is the first report of organ donation in a patient with rapidly progressive ventilator-dependent ALS...
The overlap of amyotrophic lateral sclerosis and frontotemporal dementiaCatherine Lomen-Hoerth
University of California, San Francisco, 94143, USA
Neurology 59:1077-9. 2002..One of the patients with fasciculations and a normal EMG study progressed to definite ALS over the course of 1 year...
Statistical motor unit number estimation: from theory to practiceCatherine Lomen-Hoerth
Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, Room M348, San Francisco, California 94143, USA
Muscle Nerve 28:263-72. 2003....
Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase IIIPetra Kaufmann
Department of Neurology, Clinical Coordinating Center, Columbia University, New York, NY 10032, USA
Ann Neurol 66:235-44. 2009..Our aims were to choose between two high doses of CoQ10 for ALS, and to determine if it merits testing in a Phase III clinical trial...
Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affectErik P Pioro
Section of ALS and Related Disorders, Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Ann Neurol 68:693-702. 2010..To evaluate dextromethorphan combined with ultra low-dose quinidine (DMq) for treating pseudobulbar affect (PBA) in patients with amyotrophic lateral sclerosis (ALS) or multiple sclerosis (MS)...
Exit strategies in ALS: an influence of depression or despair?Richard K Olney
Neurology 65:9-10. 2005
Cognitive impairment, frontotemporal dementia, and the motor neuron diseasesMichael J Strong
Department of Clinical Neurological Sciences and the Robarts Research Institute, London, Ontario, Canada
Ann Neurol 54:S20-3. 2003
Amyotrophic lateral sclerosis: an emerging era of collaborative gene discoveryKatrina Gwinn
National Institute for Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 2:e1254. 2007..This resource should facilitate genetic discoveries which we anticipate will ultimately provide a better understanding of the biological mechanisms of neurodegeneration in ALS...
ALS treatment strikes out while trying for a homer: the topiramate trialPetra Kaufmann
Neurology 61:434-5. 2003
Whole-genome analysis of sporadic amyotrophic lateral sclerosisTravis Dunckley
Translational Genomics Research Inst, Phoenix, AZ 85004, USA
N Engl J Med 357:775-88. 2007..Approximately 90% of persons with amyotrophic lateral sclerosis (ALS) have the sporadic form, which may be caused by the interaction of multiple environmental factors and previously unknown genes...
