M W Logue

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Calculation of multipoint likelihoods using flanking marker data: a simulation study
    Andrew W George
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    BMC Genet 6:S44. 2005
  2. ncbi request reprint Bayesian analysis of a previously published genome screen for panic disorder reveals new and compelling evidence for linkage to chromosome 7
    Mark W Logue
    Division of Statistical Genetics, Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    Am J Med Genet B Neuropsychiatr Genet 121:95-9. 2003
  3. pmc A model-integrated multipoint Bayesian analysis of hypertension in the Framingham Heart Study data finds little evidence of linkage
    Mark W Logue
    Division of Statistical Genetics, Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    BMC Genet 4:S75. 2003
  4. ncbi request reprint A posterior probability of linkage-based re-analysis of schizophrenia data yields evidence of linkage to chromosomes 1 and 17
    M W Logue
    Program for Public Health Genetics, Center for Statistical Genetics Research, Iowa City, IA 52242, USA
    Hum Hered 62:47-54. 2006
  5. ncbi request reprint A new method for computing the multipoint posterior probability of linkage
    Mark W Logue
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Hum Hered 57:90-9. 2004
  6. ncbi request reprint The incorporation of prior genomic information does not necessarily improve the performance of Bayesian linkage methods: an example involving sex-specific recombination and the two-point PPL
    Mark W Logue
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    Hum Hered 60:196-205. 2005
  7. pmc Performance comparison of two-point linkage methods using microsatellite markers flanking known disease locations
    Mark W Logue
    Center for Statistical Genetics Research, College of Public Health, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    BMC Genet 6:S141. 2005
  8. pmc A major susceptibility locus for specific language impairment is located on 13q21
    Christopher W Bartlett
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Piscataway, NJ 08854 8095, USA
    Am J Hum Genet 71:45-55. 2002
  9. ncbi request reprint The posterior probability of linkage allowing for linkage disequilibrium and a new estimate of disequilibrium between a trait and a marker
    Xinqun Yang
    Center for Statistical Genetics Research, The University of Iowa, Iowa City, Iowa 52242, USA
    Hum Hered 59:210-9. 2005
  10. pmc Examination of potential overlap in autism and language loci on chromosomes 2, 7, and 13 in two independent samples ascertained for specific language impairment
    Christopher W Bartlett
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ, USA
    Hum Hered 57:10-20. 2004

Detail Information

Publications11

  1. pmc Calculation of multipoint likelihoods using flanking marker data: a simulation study
    Andrew W George
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    BMC Genet 6:S44. 2005
    ..The flanking marker procedure performs well, even when missing data and genotyping errors are introduced...
  2. ncbi request reprint Bayesian analysis of a previously published genome screen for panic disorder reveals new and compelling evidence for linkage to chromosome 7
    Mark W Logue
    Division of Statistical Genetics, Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    Am J Med Genet B Neuropsychiatr Genet 121:95-9. 2003
    ..The results for the remainder of the genome are consistently low. The two loci identified here are also supported by independent evidence from other studies...
  3. pmc A model-integrated multipoint Bayesian analysis of hypertension in the Framingham Heart Study data finds little evidence of linkage
    Mark W Logue
    Division of Statistical Genetics, Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    BMC Genet 4:S75. 2003
    ..While the PPL analysis of this data remains inconclusive, Bayesian methodology gives us a clear mechanism for using the information gained here in further studies...
  4. ncbi request reprint A posterior probability of linkage-based re-analysis of schizophrenia data yields evidence of linkage to chromosomes 1 and 17
    M W Logue
    Program for Public Health Genetics, Center for Statistical Genetics Research, Iowa City, IA 52242, USA
    Hum Hered 62:47-54. 2006
    ..8 [Brzustowicz et al. 2000]. In the current study, we revisited this data set using a Bayesian linkage analysis technique, namely the posterior probability of linkage (PPL)...
  5. ncbi request reprint A new method for computing the multipoint posterior probability of linkage
    Mark W Logue
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Hum Hered 57:90-9. 2004
    ..This version, which we call the imputed PPL, is shown to be superior to previously developed versions...
  6. ncbi request reprint The incorporation of prior genomic information does not necessarily improve the performance of Bayesian linkage methods: an example involving sex-specific recombination and the two-point PPL
    Mark W Logue
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    Hum Hered 60:196-205. 2005
    ..We present a two-point PPL allowing for unequal male and female recombination fractions, thetaM and thetaF, and consider alternative priors on thetaM, thetaF...
  7. pmc Performance comparison of two-point linkage methods using microsatellite markers flanking known disease locations
    Mark W Logue
    Center for Statistical Genetics Research, College of Public Health, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA, USA
    BMC Genet 6:S141. 2005
    ..The pooling of the four datasets in each replicate (n = 350 pedigrees) greatly improved the chance of detecting the major genes using all five methods, but failed to increase the chance to detect D5 and D6...
  8. pmc A major susceptibility locus for specific language impairment is located on 13q21
    Christopher W Bartlett
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Piscataway, NJ 08854 8095, USA
    Am J Hum Genet 71:45-55. 2002
    ..86, genomic P value <.06 under the recessive language impairment model). Our findings underscore the utility of traditional LOD-score-based methods in finding genes for complex diseases, specifically, SLI...
  9. ncbi request reprint The posterior probability of linkage allowing for linkage disequilibrium and a new estimate of disequilibrium between a trait and a marker
    Xinqun Yang
    Center for Statistical Genetics Research, The University of Iowa, Iowa City, Iowa 52242, USA
    Hum Hered 59:210-9. 2005
    ..The estimate of D' also behaves well even in relatively small, heterogeneous samples...
  10. pmc Examination of potential overlap in autism and language loci on chromosomes 2, 7, and 13 in two independent samples ascertained for specific language impairment
    Christopher W Bartlett
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ, USA
    Hum Hered 57:10-20. 2004
    ..2003). Our results indicate that using samples selected for components of the autism phenotype may be a useful adjunct to autism genetics...
  11. ncbi request reprint Model selection and Bayesian methods in statistical genetics: summary of group 11 contributions to Genetic Analysis Workshop 15
    Michael D Swartz
    Department of Epidemiology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Genet Epidemiol 31:S96-102. 2007
    ..These group contributions exhibit the value of framing genetic problems in terms of model selection, and highlight the impact of variable selection for gene mapping...