Daniel J Lodge

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi Amphetamine activation of hippocampal drive of mesolimbic dopamine neurons: a mechanism of behavioral sensitization
    Daniel J Lodge
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 28:7876-82. 2008
  2. ncbi Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia
    Daniel J Lodge
    Departments of Neuroscience, Psychiatry, and Psychology, University of Pittsburgh, A210 Langley Hall, Pittsburgh, PA 15260, USA
    Behav Brain Res 204:306-12. 2009
  3. ncbi A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia
    Daniel J Lodge
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 29:2344-54. 2009
  4. ncbi Aversive stimuli alter ventral tegmental area dopamine neuron activity via a common action in the ventral hippocampus
    Ornella Valenti
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 31:4280-9. 2011
  5. ncbi A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia
    Kathryn M Gill
    Departments of Neuroscience, Psychiatry, and Psychology, University of Pittsburgh, Pittsburgh, PA, USA
    Neuropsychopharmacology 36:1903-11. 2011
  6. ncbi Hippocampal dysfunction and disruption of dopamine system regulation in an animal model of schizophrenia
    Daniel J Lodge
    Department of Neuroscience, Psychiatry, and Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neurotox Res 14:97-104. 2008
  7. ncbi Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia
    Daniel J Lodge
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 27:11424-30. 2007
  8. ncbi Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
    Anthony A Grace
    Departments of Neuroscience, Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Trends Neurosci 30:220-7. 2007
  9. ncbi Aberrant striatal plasticity is specifically associated with dyskinesia following levodopa treatment
    Pauline Belujon
    Departments of Neuroscience, Psychiatry, and Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Mov Disord 25:1568-76. 2010
  10. ncbi The hippocampus modulates dopamine neuron responsivity by regulating the intensity of phasic neuron activation
    Daniel J Lodge
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neuropsychopharmacology 31:1356-61. 2006

Detail Information

Publications14

  1. ncbi Amphetamine activation of hippocampal drive of mesolimbic dopamine neurons: a mechanism of behavioral sensitization
    Daniel J Lodge
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 28:7876-82. 2008
    ....
  2. ncbi Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia
    Daniel J Lodge
    Departments of Neuroscience, Psychiatry, and Psychology, University of Pittsburgh, A210 Langley Hall, Pittsburgh, PA 15260, USA
    Behav Brain Res 204:306-12. 2009
    ..Thus gestational MAM administration has been demonstrated to induce a pathodevelopmental process leading to neuroanatomical and behavioral phenotypes consistent with that observed in schizophrenia in humans...
  3. ncbi A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia
    Daniel J Lodge
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 29:2344-54. 2009
    ..Such information is central to gaining a better understanding of the disease pathophysiology and alternate pharmacotherapeutic approaches...
  4. ncbi Aversive stimuli alter ventral tegmental area dopamine neuron activity via a common action in the ventral hippocampus
    Ornella Valenti
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 31:4280-9. 2011
    ..Furthermore, the vHPC represents a critical link between context-dependent DA sensitization, stress-induced potentiation of amphetamine responsivity, and the increase in DA associated with stressors...
  5. ncbi A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia
    Kathryn M Gill
    Departments of Neuroscience, Psychiatry, and Psychology, University of Pittsburgh, Pittsburgh, PA, USA
    Neuropsychopharmacology 36:1903-11. 2011
    ..This study supports a novel treatment of schizophrenia that targets abnormal HPC output, which in turn normalizes dopaminergic neuronal activity...
  6. ncbi Hippocampal dysfunction and disruption of dopamine system regulation in an animal model of schizophrenia
    Daniel J Lodge
    Department of Neuroscience, Psychiatry, and Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neurotox Res 14:97-104. 2008
    ..Moreover, this suggests an alternate pharmacotherapeutic approach based on the normalization of hippocampal activity in the treatment of schizophrenia in humans...
  7. ncbi Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia
    Daniel J Lodge
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    J Neurosci 27:11424-30. 2007
    ..These data provide a direct link between hippocampal dysfunction and the hyper-responsivity of the DA system that is believed to underlie the augmented response to amphetamine in animal models and psychosis in schizophrenia patients...
  8. ncbi Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
    Anthony A Grace
    Departments of Neuroscience, Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Trends Neurosci 30:220-7. 2007
    ....
  9. ncbi Aberrant striatal plasticity is specifically associated with dyskinesia following levodopa treatment
    Pauline Belujon
    Departments of Neuroscience, Psychiatry, and Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Mov Disord 25:1568-76. 2010
    ..Such information is critical for understanding the cellular mechanisms underlying one of the major caveats to L-dopa therapy...
  10. ncbi The hippocampus modulates dopamine neuron responsivity by regulating the intensity of phasic neuron activation
    Daniel J Lodge
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neuropsychopharmacology 31:1356-61. 2006
    ....
  11. ncbi Comparative analysis of hepatic ethanol metabolism in Fawn-Hooded and Wistar-Kyoto rats
    Daniel J Lodge
    Department of Pharmacology, Monash University, Box 13E, Clayton, Victoria 3800, Australia
    Alcohol 30:75-9. 2003
    ....
  12. ncbi Atypical behavioural responses to CCK-B receptor ligands in Fawn-Hooded rats
    Daniel J Lodge
    Department of Pharmacology, Monash University, Wellington Road, Box 13E, Clayton, Victoria 3800, Australia
    Life Sci 74:1-12. 2003
    ....
  13. ncbi The CRF1 receptor antagonist, antalarmin, reverses isolation-induced up-regulation of dopamine D2 receptors in the amygdala and nucleus accumbens of fawn-hooded rats
    Elvan Djouma
    Department of Pharmacology, Monash University, Clayton, Victoria 3800, Australia
    Eur J Neurosci 23:3319-27. 2006
    ..Collectively, these findings demonstrate that multiple signalling systems are susceptible to modulation by social isolation and that antalarmin can reverse some, but not all, isolation-induced alterations in brain chemistry...
  14. ncbi The effect of isolation rearing on volitional ethanol consumption and central CCK/dopamine systems in Fawn-Hooded rats
    Daniel J Lodge
    Department of Pharmacology, Monash University, P O Box 13E, Clayton, VIC 3800, Australia
    Behav Brain Res 141:113-22. 2003
    ..In addition, isolation rearing induced a number of changes in central CCK/dopamine systems...