Research Topics
| C P LocherSummaryAffiliation: University of California Country: USA Publications
|
Detail Information
Publications
Suppression of human immunodeficiency virus type 1 replication by a soluble factor produced by CD8+ lymphocytes from HIV-2-infected baboonsC P Locher
Department of Medicine, University of California, San Francisco 94143 1270, USA
Immunol Lett 66:151-7. 1999..Therefore, the soluble suppressing activity of CD8+ cells in HIV-2-infected baboons may be analogous to the CD8+ cell antiviral factor described in human HIV-infected asymptomatic people...
Baboons as an animal model for human immunodeficiency virus pathogenesis and vaccine developmentC P Locher
Department of Medicine, Division of Hematology and Oncology, University of California, San Francisco, CA 94143 1270, USA
Immunol Rev 183:127-40. 2001..The results demonstrate the value of using baboons as an animal model of AIDS pathogenesis and vaccine development...
The nuclear factor kappa B and Spl binding sites do not appear to be involved in virus suppression by CD8 T lymphocytesC P Locher
Department of Medicine, Division of Hematology and Oncology, University of California, San Francisco, CA 94143-1270, USA
AIDS 15:2455-7. 2001..The results strongly suggest that the NF-B and Spl binding sites are not involved in virus suppression by CD8 T lymphocytes...
Immune responses in baboons vaccinated with HIV-2 genetic expression librariesC P Locher
Department of Medicine, Division of Hematology and Oncology, University of California, San Francisco, CA 94143 1270, USA
J Med Primatol 31:323-9. 2002..We conclude that although immunization using HIV-2 expression libraries induces immune responses, this approach does not provide protection in baboons against intravenous challenge with HIV-2...
