Research Topics
Species | Russell LocalioSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Relative risks and confidence intervals were easily computed indirectly from multivariable logistic regressionA Russell Localio
Division of Biostatistics, Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Clin Epidemiol 60:874-82. 2007..To assess alternative statistical methods for estimating relative risks and their confidence intervals from multivariable binary regression when outcomes are common...
Novel variants in the PRDX6 Gene and the risk of Acute Lung Injury following major traumaMelanie Rushefski
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, USA
BMC Med Genet 12:77. 2011..Little is known about genetic variation within the PRDX6 gene and its association with acute lung injury (ALI). In this study we sequenced the PRDX6 gene to uncover common variants, and tested association with ALI following major trauma...- Prevalence and risk factors for significant liver fibrosis among HIV-monoinfected patientsMichelle DallaPiazza
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
BMC Infect Dis 10:116. 2010..Since HIV-monoinfected patients do not routinely undergo liver biopsy, we evaluated the prevalence and risk factors of significant hepatic fibrosis in this group using the aspartate aminotransferase (AST)-to-platelet ratio index (APRI)... - Can we predict daily adherence to warfarin?: Results from the International Normalized Ratio Adherence and Genetics (IN-RANGE) StudyAlec B Platt
MSCE, University of Pennsylvania School of Medicine, 707 Blockley Hall, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
Chest 137:883-9. 2010..Currently, no comprehensive screening tool exists to help providers assess the risk of nonadherence at the time of initiation of warfarin therapy... 
Increased risk of digoxin toxicity following hospitalizationKevin Haynes
Program for the Reduction in Medication Errors, Department of Biostatistics and Epidemiology and School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Pharmacoepidemiol Drug Saf 18:28-35. 2009..The objective of the study was to identify health care system factors that affect the risk of digoxin toxicity for older adults on digoxin...- Incidence of transaminitis among HIV-infected patients with occult hepatitis BVincent Lo Re
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Clin Virol 43:32-6. 2008..This information is needed to determine the importance of detecting and treating occult HBV in this population... - Impact of electronic health record-based alerts on influenza vaccination for children with asthmaAlexander G Fiks
Pediatric Generalist Research Group, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Pediatrics 124:159-69. 2009..The goal was to assess the impact of influenza vaccine clinical alerts on missed opportunities for vaccination and on overall influenza immunization rates for children and adolescents with asthma... - Moderate and high affinity serotonin reuptake inhibitors increase the risk of upper gastrointestinal toxicityJames D Lewis
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Pharmacoepidemiol Drug Saf 17:328-35. 2008..This study examined the effect of medications that inhibit serotonin uptake on upper gastrointestinal toxicity... - One-year results of the Think Health! study of weight management in primary care practicesShiriki K Kumanyika
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
Obesity (Silver Spring) 20:1249-57. 2012..We conclude that the Basic Plus approach of moderate-intensity counseling by PCPs and their staff can facilitate modest weight loss, with clinically significant weight loss in high program attenders... - Impact of pulmonary artery pressure on exercise function in severe COPDMichael W Sims
Department of Pulmonary, Allergy, and Critical Care, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Chest 136:412-9. 2009..Although pulmonary hypertension commonly complicates COPD, the functional consequences of increased pulmonary artery pressures in patients with this condition remain poorly defined... - Risk factors for lymphedema after breast cancer treatmentSandra A Norman
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Cancer Epidemiol Biomarkers Prev 19:2734-46. 2010..As cancer treatments evolve, it is important to reevaluate their effect on lymphedema risk in breast cancer survivors... - Relationship between adherence to hepatitis C virus therapy and virologic outcomes: a cohort studyVincent Lo Re
University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Ann Intern Med 155:353-60. 2011..Adherence to therapy with pegylated interferon and ribavirin for hepatitis C virus (HCV) infection has been incompletely examined... - Hormone therapy and fatal breast cancerSandra A Norman
Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Pharmacoepidemiol Drug Saf 19:440-7. 2010..Using a population-based case-control design, we estimated incidence rate ratios of fatal breast cancer in postmenopausal hormone therapy (HT) users compared to non-users by type, duration, and recency of HT use... - Self-reported hepatitis B and C virus infections had low sensitivity among HIV-infected patientsVincent Lo Re
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Clin Epidemiol 60:294-9. 2007..To determine the validity of self-reported hepatitis B virus (HBV) and hepatitis C virus (HCV) in HIV-infected injection drug users (IDUs) vs. nonIDUs... - Benefit of screening mammography in reducing the rate of late-stage breast cancer diagnoses (United States)Sandra A Norman
Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania, 801 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
Cancer Causes Control 17:921-9. 2006..We studied the benefit of modern mammography screening in community settings, evaluating age-related differences in rates of late-stage breast cancer detection... - Patient reported receipt of medication instructions for warfarin is associated with reduced risk of serious bleeding eventsJoshua P Metlay
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Gen Intern Med 23:1589-94. 2008..Adverse drug events are an important cause of preventable hospitalizations... - Diagnostic E-codes for commonly used, narrow therapeutic index medications poorly predict adverse drug eventsCharles E Leonard
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Clin Epidemiol 61:561-71. 2008..We sought to examine the validity of specific hospital discharge codes in identifying drug toxicity precipitating hospitalization, among elderly users of high-risk medications... - Corticosteroids may improve clinical outcomes during hospitalization for Henoch-Schönlein purpuraPamela F Weiss
Division of Rheumatology, Children s Hospital of Philadelphia, and Department of Pediatrics, Center for Clinical Epidemiology and Biostatistics, Leonard Davis Institute of Health Economics, University of Pennsylvania School of Medicine, Room 1539, North Campus, 3535 Market St, Philadelphia, PA 19104, USA
Pediatrics 126:674-81. 2010..To characterize the effect of corticosteroid exposure on clinical outcomes in children hospitalized with new-onset Henoch-Schönlein purpura (HSP)... - Risk of serious upper gastrointestinal toxicity with over-the-counter nonaspirin nonsteroidal anti-inflammatory drugsJames D Lewis
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Gastroenterology 129:1865-74. 2005..Less is known about over-the-counter (OTC) NANSAIDs, which are typically used at lower doses and for shorter durations. This study assessed the risk of toxicity with OTC NANSAIDs... - Plasma leptin levels are associated with coronary atherosclerosis in type 2 diabetesMuredach P Reilly
Cardiovascular Division, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, USA
J Clin Endocrinol Metab 89:3872-8. 2004..Whether leptin signaling promotes atherosclerosis directly or represents a therapeutic target for the prevention of atherosclerotic cardiovascular disease remains to be explored... - The impact of emergency department crowding measures on time to antibiotics for patients with community-acquired pneumoniaJesse M Pines
Department of Emergency Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Ann Emerg Med 50:510-6. 2007..We seek to determine the impact of emergency department (ED) crowding on delays in antibiotic administration for patients with community-acquired pneumonia... - Coronary artery calcification and cardiovascular risk factors: impact of the analytic approachMuredach P Reilly
Cardiovascular Division, Department of Medicine, Center for Experimental Therapeutics, University of Pennsylvania School of Medicine, 909 BRB 2 3, 421 Curie Blvd, Philadelphia, PA 19004 6160, USA
Atherosclerosis 173:69-78. 2004..We present analytic approaches that are likely to provide consistent results and recommend the use of at least two distinct multivariable methods... - Risk factors for nonadherence to warfarin: results from the IN-RANGE studyAlec B Platt
Department of Medicine, University of Pennsylvania School of Medicine, PA, USA
Pharmacoepidemiol Drug Saf 17:853-60. 2008..Warfarin is widely used to prevent stroke and venous thromboembolism despite its narrow therapeutic window. Warfarin nonadherence is a substantial problem, but risk factors have not been well elucidated... - Epidemiologic features of the presentation of critical congenital heart disease: implications for screeningAmy H Schultz
Department of, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Pediatrics 121:751-7. 2008..These descriptive parameters must be defined to evaluate the impact and feasibility of any proposed screening strategy... - Construct validity of the definition of primary graft dysfunction after lung transplantationJason D Christie
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
J Heart Lung Transplant 29:1231-9. 2010..This study tested the discriminant validity of International Society for Heart and Lung Transplantation (ISHLT) primary graft dysfunction (PGD) grades with lung injury biomarker profiles and survival... - Risk factors and predictors for candidemia in pediatric intensive care unit patients: implications for preventionTheoklis E Zaoutis
Division of Infectious Diseases, Center for Pediatric Clinical Effectiveness, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Clin Infect Dis 51:e38-45. 2010..Few data exist on risk factors for candidemia in pediatric intensive care unit (PICU) patients... - Shared decision-making in pediatrics: a national perspectiveAlexander G Fiks
ediatric Research Consortium, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatrics 126:306-14. 2010.... - Neither panacea nor black box: responding to three Journal of Biomedical Informatics papers on computerized physician order entry systemsRoss Koppel
Department of Sociology and Center for Clinical Epidemiology and Biostatistics of the School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
J Biomed Inform 38:267-9. 2005 - Intercellular adhesion molecule 1 (ICAM-1) gene variant is associated with coronary artery calcification independent of soluble ICAM-1 levelsMuredach P Reilly
Cardiovascular Division, Department of Medicine, The Center for Experimental Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Investig Med 52:515-22. 2004.... - Adherence to hepatitis C virus therapy and early virologic outcomesVincent Lo Re
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
Clin Infect Dis 48:186-93. 2009..We examined the relationship between adherence to pegylated interferon and ribavirin therapy, measured by pharmacy refill, and HCV suppression during the initial 12 weeks of therapy... - Risk factors for renal failure in pediatric patients with acute myeloid leukemia: a retrospective cohort studyBrian T Fisher
Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Pediatr Blood Cancer 55:655-61. 2010..This study aims to evaluate the rate of ARF in AML patients and to delineate the impact of age, race, various co-morbid conditions and antimicrobial agents on the development of ARF... - Bias correction with a single null marker for population stratification in candidate gene association studiesYiting Wang
Department of Biostatistics, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6021, USA
Hum Hered 59:165-75. 2005..Our results suggested that marker choice and the specific treatment of that marker in analysis greatly influenced bias correction... - Evaluating bias due to population stratification in epidemiologic studies of gene-gene or gene-environment interactionsYiting Wang
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, 904 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104-6021, USA
Cancer Epidemiol Biomarkers Prev 15:124-32. 2006..However, when linkage disequilibrium among genes or correlations among genes and environments were small, biases to main effects or interaction odds ratios were small to nonexistent... - Variation in inpatient therapy and diagnostic evaluation of children with Henoch Schönlein purpuraPamela F Weiss
Division of Rheumatology, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
J Pediatr 155:812-818.e1. 2009..To describe variation regarding inpatient therapy and evaluation of children with Henoch Schönlein purpura (HSP) admitted to children's hospitals across the United States... - Variation in pregnancy outcomes following statewide implementation of a prenatal home visitation programDavid M Rubin
Division of General Pediatrics, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104 4399, USA
Arch Pediatr Adolesc Med 165:198-204. 2011..To examine, following statewide dissemination, the influence of an evidence-based home visitation program for first-time mothers on reductions of subsequent pregnancies across time and different locations... - Outcomes attributable to neonatal candidiasisTheoklis E Zaoutis
Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Clin Infect Dis 44:1187-93. 2007..The incidence of candidiasis has increased in neonatal intensive care units, and invasive candidiasis is associated with significant morbidity and mortality. However, few data exist on outcomes directly attributable to neonatal candidiasis... - Oseltamivir shortens hospital stays of critically ill children hospitalized with seasonal influenza: a retrospective cohort studySusan E Coffin
Division of Infectious Diseases, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatr Infect Dis J 30:962-6. 2011..The effect of oseltamivir on outcomes of hospitalized children is unknown. The primary objective of this study was to determine whether oseltamivir improves outcomes of critically ill children hospitalized with influenza... - Identifying and quantifying medication errors: evaluation of rapidly discontinued medication orders submitted to a computerized physician order entry systemRoss Koppel
Department of Sociology, University of Pennsylvania, Philadelphia, PA, USA
J Am Med Inform Assoc 15:461-5. 2008..This measure offers a rapid, constant, inexpensive, and objective method to identify medication orders with a high probability of error. It may also serve as a screening and teaching mechanism for physicians-in-training... - Validity of The Health Improvement Network (THIN) for epidemiologic studies of hepatitis C virus infectionVincent Lo Re
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, PA 19104 6021, USA
Pharmacoepidemiol Drug Saf 18:807-14. 2009..We determined the accuracy of HCV diagnostic codes within The Health Improvement Network (THIN), an electronic database containing medical record data from general medical practices in the United Kingdom... - Electronic medical record use in pediatric primary careAlexander G Fiks
The Pediatric Research Consortium PeRC, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
J Am Med Inform Assoc 18:38-44. 2011..To characterize patterns of electronic medical record (EMR) use at pediatric primary care acute visits... - The effect of cardiac troponin testing on clinical care in a veterans population: a randomized controlled trialMichael Berkwits
Philadelphia VA Medical Center and the Division of General Internal Medicine, University of Pennsylvania Health System, Philadelphia, PA, USA
J Gen Intern Med 20:584-92. 2005..Cardiac troponin is more accurate than creatine kinase (CK) testing for detecting myocardial injury in patients with acute coronary syndromes (ACS), but its effects on clinical care compared with CK testing alone is open to question... - The association between emergency department crowding and hospital performance on antibiotic timing for pneumonia and percutaneous intervention for myocardial infarctionJesse M Pines
Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
Acad Emerg Med 13:873-8. 2006..Antibiotics within four hours of arrival for patients with pneumonia and percutaneous intervention (PCI) within two hours for patients with acute myocardial infarction (AMI) are standard measures of emergency department (ED) quality... - Characterization of interpersonal violence events involving young adolescent girls vs events involving young adolescent boysCynthia J Mollen
Department of Pediatrics, Division of Emergency Medicine, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Arch Pediatr Adolesc Med 158:545-50. 2004..Multiple studies have demonstrated that girls are engaging in interpersonal violence. However, little is known about the potentially unique aspects of violent events involving girls... - Extrinsic risk factors for pressure ulcers early in the hospital stay: a nested case-control studyMona Baumgarten
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, USA
J Gerontol A Biol Sci Med Sci 63:408-13. 2008.... - Impact of clinical alerts within an electronic health record on routine childhood immunization in an urban pediatric populationAlexander G Fiks
Pediatric Research Consortium, Children s Hospital of Philadelphia, 3535 Market St, Room 1546, Philadelphia, PA 19104, USA
Pediatrics 120:707-14. 2007.... - Lymphedema in breast cancer survivors: incidence, degree, time course, treatment, and symptomsSandra A Norman
Department of Medicine, Division of Hematology Oncology, Center for Clinical Epidemiologyand Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Clin Oncol 27:390-7. 2009..To examine the incidence, degree, time course, treatment, and symptoms of lymphedema in breast cancer survivors... - Longitudinal and repeated cross-sectional cluster-randomization designs using mixed effects regression for binary outcomes: bias and coverage of frequentist and Bayesian methodsA Russell Localio
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Stat Med 25:2720-36. 2006..The performance of common statistical tools for the analysis of cluster randomization designs depends heavily on the precise design, the number of clusters, and the variability of baseline outcomes and treatment effects across centres... - Predictors of recall of over-the-counter and prescription non-steroidal anti-inflammatory drug exposureJames D Lewis
Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Pharmacoepidemiol Drug Saf 15:39-45. 2006..Because of the difficulty in establishing a gold standard, data on accuracy of recall of over-the-counter (OTC) medication use are sparse... - Women of child-bearing age have better inhospital cardiac arrest survival outcomes than do equal-aged menAlexis A Topjian
Department of Anesthesia and Critical Care Medicine, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Crit Care Med 38:1254-60. 2010..Our objective was to determine whether women of child-bearing age are more likely than men to survive to hospital discharge after in-hospital cardiac arrest... - Validation of self-reported screening mammography histories among women with and without breast cancerSandra A Norman
Center for Clinical Epidemiology and Biostatistics and Department of Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia 19104 6021, USA
Am J Epidemiol 158:264-71. 2003..Therefore, odds ratios will likely be biased toward the null, underestimating screening efficacy... - Home visitation program effectiveness and the influence of community behavioral norms: a propensity score matched analysis of prenatal smoking cessationMeredith Matone
PolicyLab, The Children s Hospital of Philadelphia, Philadelphia, PA, USA
BMC Public Health 12:1016. 2012.... - The relationship between mental health diagnosis and treatment with second-generation antipsychotics over time: a national study of U.S. Medicaid-enrolled childrenMeredith Matone
PolicyLab, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Health Serv Res 47:1836-60. 2012..To describe the relationship between mental health diagnosis and treatment with antipsychotics among U.S. Medicaid-enrolled children over time... - Incidence, complications, and risk factors for prolonged stay in children hospitalized with community-acquired influenzaSusan E Coffin
Division of General Pediatrics, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Pediatrics 119:740-8. 2007.... - Multimodality screening of high-risk women: a prospective cohort studySusan P Weinstein
University of Pennsylvania Health System, Radiology, 1 Silverstein Bldg, 3400 Spruce St, Philadelphia, PA, USA
J Clin Oncol 27:6124-8. 2009.... - Modifiable risk factors for breast cancer recurrence: what can we tell survivors?Sandra A Norman
Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6021, USA
J Womens Health (Larchmt) 16:177-90. 2007.... - Prolonged intravenous therapy versus early transition to oral antimicrobial therapy for acute osteomyelitis in childrenTheoklis Zaoutis
Division of Infectious Diseases, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, CHOP North, Suite 1527, Philadelphia, PA 19104, USA
Pediatrics 123:636-42. 2009..We sought to compare the effectiveness of early transition from intravenous to oral antimicrobial therapy versus prolonged intravenous antimicrobial therapy for the treatment of children with acute osteomyelitis... - Impact of immunization at sick visits on well-child careAlexander G Fiks
Pediatric Research Consortium, Children s Hospital of Philadelphia, 3535 Market St, Philadelphia, PA 19104, USA
Pediatrics 121:898-905. 2008..We assessed the impact of immunization at sick visits on subsequent and overall well-child care... - The association of early transfusion with acute lung injury in patients with severe injuryDaniel N Holena
Division of Traumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
J Trauma Acute Care Surg 73:825-31. 2012..We hypothesized that the relationship between PRBC delivery and ALI risk varies through time after injury... - Local macroeconomic trends and hospital admissions for child abuse, 2000-2009Joanne N Wood
PolicyLab and General Pediatrics, The Children s Hospital of Philadelphia 3535 Market St, Room 1517, Philadelphia, PA 19104, USA
Pediatrics 130:e358-64. 2012..To examine the relationship between local macroeconomic indicators and physical abuse admission rates to pediatric hospitals over time... - Survival associated with treatment vs observation of localized prostate cancer in elderly menYu Ning Wong
Division of Population Science, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
JAMA 296:2683-93. 2006..Prostate-specific antigen screening has led to an increase in the diagnosis and treatment of localized prostate cancer. However, the role of active treatment of low- and intermediate-risk disease in elderly men is controversial... - State variation in psychotropic medication use by foster care children with autism spectrum disorderDavid M Rubin
Division of General Pediatrics, Children s Hospital of Philadelphia, PolicyLab, Center to Bridge Research, Practice, and Policy, Safe Place, Philadelphia, Pennsylvania 19104, USA
Pediatrics 124:e305-12. 2009.... - Cefepime and mortality in pediatric acute myelogenous leukemia: a retrospective cohort studyBrian T Fisher
Division of Infectious Diseases, The Children s Hospital of Philadelphia, and Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Pediatr Infect Dis J 28:971-5. 2009..We evaluated the association of cefepime and other beta-lactam antibiotic exposures with all cause in-hospital mortality in pediatric AML patients... - The impact of placement stability on behavioral well-being for children in foster careDavid M Rubin
Pediatric Generalist Research Group, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Pediatrics 119:336-44. 2007..This study sought to disentangle this cascading relationship in order to identify the independent impact of placement stability on behavioral outcomes downstream... - Role of computerized physician order entry systems in facilitating medication errorsRoss Koppel
Department of Sociology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 USA
JAMA 293:1197-203. 2005..Published studies report that CPOE reduces medication errors up to 81%. Few researchers, however, have focused on the existence or types of medication errors facilitated by CPOE... - Statistical characteristics of area under the receiver operating characteristic curve for a simple prognostic model using traditional and bootstrapped approachesDavid J Margolis
Department of Dermatology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19004, USA
J Clin Epidemiol 55:518-24. 2002..We further show that for our simple prognostic model a bootstrap z-statistic approach is preferred over the trapezoidal method when comparing the AROCs of two related models... - Decreased post-transplant survival among heart transplant recipients with pre-transplant hepatitis C virus positivityIngi Lee
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
J Heart Lung Transplant 30:1266-74. 2011..However, there have been few studies examining whether HCV infection reduces survival after heart transplantation... - Design, recruitment and start up of a primary care weight loss trial targeting African American and Hispanic adultsShiriki Kumanyika
Center for Clinical Epidemiology and Biostatistics, 8th Floor Blockley Hall, 423 Guardian Drive, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
Contemp Clin Trials 32:215-24. 2011..The study will have particular relevance to African Americans and women... - Evaluating bias due to population stratification in case-control association studies of admixed populationsYiting Wang
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104-6021, USA
Genet Epidemiol 27:14-20. 2004..Therefore, bias due to PS alone may be small when baseline risk differences are small within major categories of admixed ethnicity, such as African Americans... - Clinicians required very high sensitivity of a bacteremia prediction ruleEbbing Lautenbach
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
J Clin Epidemiol 57:1104-6. 2004..However, no such models have been accepted into general clinical use. The goal of this study was to determine physicians' criteria for acceptability of a bacteremia clinical prediction rule... - Gliomatosis cerebri: 20 years of experience at the Children's Hospital of PhiladelphiaGregory T Armstrong
Division of Oncology, The Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Cancer 107:1597-606. 2006..In this report, the authors describe the largest cohort of children to date with GC and explore relations between potential prognostic factors, treatment, and survival... - An alternative method of acute lung injury classification for use in observational studiesChirag V Shah
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Blockley Hall, 423 Guardian Dr, Philadelphia, PA, USA
Chest 138:1054-61. 2010..We assessed the impact of excluding patients with difficult-to-classify or equivocal ALI diagnosis on clinical and genetic risk factor associations for ALI after trauma... - C-reactive protein and coronary artery calcification: The Study of Inherited Risk of Coronary Atherosclerosis (SIRCA)Muredach P Reilly
Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, USA
Arterioscler Thromb Vasc Biol 23:1851-6. 2003..In the largest study to date, we examined the association of plasma CRP with coronary artery calcification (CAC) in 914 asymptomatic subjects in the Study of Inherited Risk of Coronary Atherosclerosis (SIRCA)... - Validation of a Pediatric Primary Care Network in a US Metropolitan Region as a Community-Based Infectious Disease Surveillance SystemKristen A Feemster
Division of Infectious Diseases, Department of Pediatrics, The Children s Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Interdiscip Perspect Infect Dis 2011:219859. 2011..Observed population rates of an infectious disease did not significantly differ suggesting that the network can potentially provide valid disease estimates for the community population... - Hepatitis C virus seropositivity in organ donors and survival in heart transplant recipientsLeanne B Gasink
Division of Infectious Diseases of the Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
JAMA 296:1843-50. 2006..Little is known about the effect of donor HCV positivity on survival in cardiac transplantation... - Prevalence, risk factors, and outcomes for occult hepatitis B virus infection among HIV-infected patientsVincent Lo Re
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
J Acquir Immune Defic Syndr 44:315-20. 2007..The prevalence of occult HBV in HIV-infected patients remains controversial, and the risk factors and clinical significance are unknown... - Measuring screening intensity in case-control studies of the efficacy of mammographyA Russell Localio
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, 19104 6021, USA
Am J Epidemiol 164:272-81. 2006..Assessing the effect of screening intensity in case-control studies of mammography is possible if principles and methods for misclassification and measurement error guide the analysis... - Placement changes and emergency department visits in the first year of foster careDavid M Rubin
Division of General Pediatrics, Pediatric Generalist Research Group, Safe Place Center for Child Protection and Health, Philadelphia, PA, USA
Pediatrics 114:e354-60. 2004..The secondary aim was to compare ED visit rates with rates of visits to other ambulatory care settings among children in foster care and other Medicaid-eligible children not in foster care... - Relationship between coronary angioplasty laboratory volume and outcomes after hospital dischargeStephen E Kimmel
Center for Clinical Epidemiology and Biostatistics and the Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
Am Heart J 143:833-40. 2002.... - Initial evaluation of rectal bleeding in young persons: a cost-effectiveness analysisJames D Lewis
Center for Clinical Epidemiology and Biostatistics, Blockley Hall, 9th Floor, 423 Guardian Drive, Philadelphia, PA 19104-6021, USA
Ann Intern Med 136:99-110. 2002..CONCLUSIONS: Evaluation of the colon of persons 25 to 45 years of age with otherwise asymptomatic rectal bleeding increases the life expectancy at a cost comparable to that of colon cancer screening... - Molecular analysis of nondisjunction in mice heterozygous for a Robertsonian translocationLara A Underkoffler
Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA
Genetics 161:1219-24. 2002..These results show that molecular genotyping provides a valuable tool for understanding factors influencing meiotic nondisjunction in mammals... - Placement stability and mental health costs for children in foster careDavid M Rubin
Pediatric Generalist Research Group, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
Pediatrics 113:1336-41. 2004..The secondary aim is to test the hypothesis that foster care children are also more likely to generate high costs for mental health services if they generate higher costs for non-mental health claims... - Trends in operative management of pediatric splenic injury in a regional trauma systemDaniela H Davis
Naval Medical Center Portsmouth, Portsmouth, Virginia, USA
Pediatrics 115:89-94. 2005.... - Pressure ulcers among elderly patients early in the hospital stayMona Baumgarten
Department of Epidemiology and Preventive Medicine, Division of Gerontology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
J Gerontol A Biol Sci Med Sci 61:749-54. 2006..The goals of this study were to estimate the incidence of hospital-acquired pressure ulcers in the first 2 days of the hospital stay and to identify patient characteristics associated with higher incidence... - Rosiglitazone: a thunderstorm from scarce and fragile dataCynthia D Mulrow
Ann Intern Med 147:585-7. 2007 - Association between primary care practice characteristics and emergency department use in a medicaid managed care organizationRobert A Lowe
Center for Policy and Research in Emergency Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA
Med Care 43:792-800. 2005..Many patients use emergency departments (EDs) for primary care. Previous studies have found that patient characteristics affect ED utilization. However, such studies have led to few policy changes... - Health care use of children whose female caregivers have intimate partner violence historiesMegan H Bair-Merritt
Division of General Pediatrics and Adolescent Medicine, Johns Hopkins School of Medicine, 200 N Wolfe St, Office 2021, Baltimore, MD 21287, USA
Arch Pediatr Adolesc Med 162:134-9. 2008..To determine whether prior exposure to intimate partner violence (IPV) is associated with children's subsequent emergency department (ED) visits and hospitalizations... - Attitudes and beliefs concerning prostate cancer genetic screeningDavid J Doukas
Department of Family and Geriatric Medicine, Institute of Bioethics, Public Policy and Law, University of Louisville, KY 40202, USA
Clin Genet 66:445-51. 2004..The relationship of men to others, family and society, require further investigation in this and other aspects of genetic testing...