J C Lo

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint "Buffalo hump" in men with HIV-1 infection
    J C Lo
    Division of Endocrinology, San Francisco General Hospital, CA 94110, USA
    Lancet 351:867-70. 1998
  2. pmc The effects of low-dose growth hormone in HIV-infected men with fat accumulation: a pilot study
    Joan C Lo
    Div of Endocrinology, General Clinical Research Center at San Francisco General Hospital, San Francisco, California 94110, USA
    Clin Infect Dis 39:732-5. 2004
  3. ncbi request reprint Normal female infants born of mothers with classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency
    J C Lo
    Department of Medicine, University of California, San Francisco 94143, USA
    J Clin Endocrinol Metab 84:930-6. 1999
  4. ncbi request reprint Increased prevalence of subclinical and clinical hypothyroidism in persons with chronic kidney disease
    Joan C Lo
    Divisions of Endocrinology and Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Kidney Int 67:1047-52. 2005
  5. ncbi request reprint The effects of recombinant human growth hormone on body composition and glucose metabolism in HIV-infected patients with fat accumulation
    J C Lo
    Division of Endocrinology, Department of Medicine, University of California San Francisco, San Francisco, California 94143, USA
    J Clin Endocrinol Metab 86:3480-7. 2001
  6. ncbi request reprint Altered fat distribution in HIV-positive men on nucleoside analog reverse transcriptase inhibitor therapy
    K Mulligan
    Department of Medicine, University of California San Francisco, 94110, USA
    J Acquir Immune Defic Syndr 26:443-8. 2001
  7. ncbi request reprint Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection
    K Mulligan
    Department of Medicine, University of California, San Francisco General Hospital, 94110, USA
    J Acquir Immune Defic Syndr 23:35-43. 2000
  8. pmc Metabolic effects of indinavir in healthy HIV-seronegative men
    M A Noor
    Department of Medicine, University of California at San Francisco, California, USA
    AIDS 15:F11-8. 2001
  9. ncbi request reprint Pregnancy outcomes in women with congenital virilizing adrenal hyperplasia
    J C Lo
    Department of Medicine, University of California, San Francisco, USA
    Endocrinol Metab Clin North Am 30:207-29. 2001
  10. pmc Single-dose lopinavir-ritonavir acutely inhibits insulin-mediated glucose disposal in healthy volunteers
    Grace A Lee
    Department of Medicine, University of California, San Francisco, California, USA
    Clin Infect Dis 43:658-60. 2006

Detail Information

Publications29

  1. ncbi request reprint "Buffalo hump" in men with HIV-1 infection
    J C Lo
    Division of Endocrinology, San Francisco General Hospital, CA 94110, USA
    Lancet 351:867-70. 1998
    ..Enlargement of the dorsocervical fat pad ("buffalo hump") has been reported in numerous HIV-1-infected patients. Some investigators have speculated that this finding is associated with protease-inhibitor treatment...
  2. pmc The effects of low-dose growth hormone in HIV-infected men with fat accumulation: a pilot study
    Joan C Lo
    Div of Endocrinology, General Clinical Research Center at San Francisco General Hospital, San Francisco, California 94110, USA
    Clin Infect Dis 39:732-5. 2004
    ..Visceral adipose tissue (VAT) levels did not change significantly for the group as a whole, although a reduction in the VAT level was seen in patients with a greater VAT level at baseline...
  3. ncbi request reprint Normal female infants born of mothers with classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency
    J C Lo
    Department of Medicine, University of California, San Francisco 94143, USA
    J Clin Endocrinol Metab 84:930-6. 1999
    ..Recommendations for the management of pregnancy and delivery in these patients are discussed...
  4. ncbi request reprint Increased prevalence of subclinical and clinical hypothyroidism in persons with chronic kidney disease
    Joan C Lo
    Divisions of Endocrinology and Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Kidney Int 67:1047-52. 2005
    ..Previous studies have suggested a higher prevalence of thyroid abnormalities in persons with end-stage renal disease. However, little is known regarding the epidemiology of thyroid disorders in persons with less severe kidney dysfunction...
  5. ncbi request reprint The effects of recombinant human growth hormone on body composition and glucose metabolism in HIV-infected patients with fat accumulation
    J C Lo
    Division of Endocrinology, Department of Medicine, University of California San Francisco, San Francisco, California 94143, USA
    J Clin Endocrinol Metab 86:3480-7. 2001
    ..We also recommend a screening oral glucose tolerance test be performed to exclude subjects at risk for GH-induced hyperglycemia...
  6. ncbi request reprint Altered fat distribution in HIV-positive men on nucleoside analog reverse transcriptase inhibitor therapy
    K Mulligan
    Department of Medicine, University of California San Francisco, 94110, USA
    J Acquir Immune Defic Syndr 26:443-8. 2001
    ..Our results, which have been obtained retrospectively, are intended to provide the impetus for prospective, controlled studies of the interactions among drug and host factors in the development of fat distribution abnormalities...
  7. ncbi request reprint Hyperlipidemia and insulin resistance are induced by protease inhibitors independent of changes in body composition in patients with HIV infection
    K Mulligan
    Department of Medicine, University of California, San Francisco General Hospital, 94110, USA
    J Acquir Immune Defic Syndr 23:35-43. 2000
    ..However, at the moment, the risks associated with these metabolic effects do not appear to outweigh improvements in survival seen with PI therapy...
  8. pmc Metabolic effects of indinavir in healthy HIV-seronegative men
    M A Noor
    Department of Medicine, University of California at San Francisco, California, USA
    AIDS 15:F11-8. 2001
    ..CONCLUSIONS: In the absence of HIV infection, treatment with indinavir for 4 weeks causes insulin resistance independent of increases in visceral adipose tissue or lipid and lipoprotein levels...
  9. ncbi request reprint Pregnancy outcomes in women with congenital virilizing adrenal hyperplasia
    J C Lo
    Department of Medicine, University of California, San Francisco, USA
    Endocrinol Metab Clin North Am 30:207-29. 2001
    ..In most cases, successful gestational management requires the close coordination of care between the obstetrician and endocrinologist...
  10. pmc Single-dose lopinavir-ritonavir acutely inhibits insulin-mediated glucose disposal in healthy volunteers
    Grace A Lee
    Department of Medicine, University of California, San Francisco, California, USA
    Clin Infect Dis 43:658-60. 2006
    ..Insulin resistance from protease inhibitors may decrease with prolonged use; an increase in adiponectin levels may mediate this effect...
  11. pmc Effects of ritonavir and amprenavir on insulin sensitivity in healthy volunteers
    Grace A Lee
    Department of Medicine, University of California, San Francisco, California, USA
    AIDS 21:2183-90. 2007
    ..Some HIV protease inhibitors (PIs) have been shown to induce insulin resistance in vitro but the degree to which specific PIs affect insulin sensitivity in humans is less well understood...
  12. ncbi request reprint Indinavir increases glucose production in healthy HIV-negative men
    Jean Marc Schwarz
    Department of Medicine, University of California, San Francisco, CA, USA
    AIDS 18:1852-4. 2004
    ..During the euglycemic hyperinsulinemic clamp, indinavir blunted the ability of insulin to suppress glucose production. Therefore, indinavir worsens hepatic insulin sensitivity, increasing endogenous glucose production...
  13. pmc The metabolic effects of lopinavir/ritonavir in HIV-negative men
    Grace A Lee
    Metabolism Section 111F, San Francisco Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    AIDS 18:641-9. 2004
    ..Therefore, we tested the effects of the PI combination lopinavir and ritonavir on glucose and lipid metabolism in HIV-negative subjects...
  14. pmc Chronic kidney disease and cognitive function in older adults: findings from the chronic renal insufficiency cohort cognitive study
    Kristine Yaffe
    Department of Psychiatry, School of Medicine, University of California at San Francisco, San Francisco, California, USA
    J Am Geriatr Soc 58:338-45. 2010
    ....
  15. pmc Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study
    Mustafa A Noor
    Department of Medicine, University of California, Berkeley, California, USA
    AIDS 16:F1-8. 2002
    ..We hypothesized that a single dose of the PI indinavir resulting in therapeutic plasma concentrations would acutely decrease insulin-stimulated glucose disposal in healthy human volunteers...
  16. ncbi request reprint Occult virilizing ovarian tumours in postmenopausal women: problems in evaluation with reference to a case
    K C Loh
    Department of Pathology, University of California, San Francisco, USA
    Ann Acad Med Singapore 27:712-6. 1998
    ..This approach avoids unnecessary investigations and delays in definitive management...
  17. ncbi request reprint The metabolic syndrome and chronic kidney disease
    Carmen A Peralta
    Department of Medicine, University of California San Francisco, CA 94118, USA
    Curr Opin Nephrol Hypertens 15:361-5. 2006
    ..Over the past decade, the metabolic syndrome has emerged as a critically important risk factor for cardiovascular disease...
  18. ncbi request reprint The relationship between nucleoside analogue treatment duration, insulin resistance, and fasting arterialized lactate level in patients with HIV infection
    Joan C Lo
    Department of Medicine, University of California San Francisco, CA, USA
    Clin Infect Dis 41:1335-40. 2005
    ..We examined the association of NRTI treatment duration and lactate level in human immunodeficiency virus (HIV)-infected patients and assessed the relationship of treatment duration and lactate level with insulin resistance...
  19. ncbi request reprint Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection
    Priscilla Y Hsue
    Division of Cardiology, San Francisco General Hospital, and the Department of Medicine, University of California, San Francisco, CA 94110, USA
    Circulation 109:1603-8. 2004
    ..HIV-infected patients may be at increased risk for coronary events. The purpose of this study was to identify predictors of carotid intima-media thickness (IMT) in HIV patients at baseline and to measure IMT progression over 1 year...
  20. ncbi request reprint Metabolic syndrome and the risk for chronic kidney disease among nondiabetic adults
    Manjula Kurella
    University of California San Francisco, Department of Nephrology, Laurel Heights, 3333 California Street, Suite 430, San Francisco, CA 94118 1211, USA
    J Am Soc Nephrol 16:2134-40. 2005
    ..24 (95% CI, 1.01 to 1.51). The metabolic syndrome is independently associated with an increased risk for incident CKD in nondiabetic adults...
  21. ncbi request reprint Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone
    Laura A Napolitano
    Gladstone Institute of Virology and Immunology, University of California at San Francisco, San Francisco, CA 94141, USA
    AIDS 16:1103-11. 2002
    ..To determine whether treatment with growth hormone (GH) enhances thymopoiesis in individuals infected with HIV-1...
  22. ncbi request reprint Value of the sagittal abdominal diameter in coronary heart disease risk assessment: cohort study in a large, multiethnic population
    Carlos Iribarren
    Division of Research, Kaiser Permanente of Northern California, Oakland 94612, and Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco General Hospital, CA, USA
    Am J Epidemiol 164:1150-9. 2006
    ..In conclusion, standing sagittal abdominal diameter was a strong predictor of CHD independently of BMI and added incremental CHD risk prediction at each level of BMI...
  23. ncbi request reprint The association of genetic polymorphisms in sex hormone biosynthesis and action with insulin sensitivity and diabetes mellitus in women at midlife
    Joan C Lo
    Division of Research, Kaiser Permanente Northern California, Oakland, California, USA
    Am J Med 119:S69-78. 2006
    ..The strong association of 17HSD and diabetes in Caucasian women has not been previously reported and should be further investigated...
  24. ncbi request reprint Effects of recombinant human growth hormone on hepatic lipid and carbohydrate metabolism in HIV-infected patients with fat accumulation
    Jean Marc Schwarz
    Department of Nutritional Sciences and Toxicology, University of California Berkeley, Berkeley, California 94720 3104, USA
    J Clin Endocrinol Metab 87:942. 2002
    ..The combined implications of these positive and negative metabolic effects for cardiovascular disease risk remain unknown...
  25. ncbi request reprint HIV protease inhibitors increase adiponectin levels in HIV-negative men
    Grace A Lee
    J Acquir Immune Defic Syndr 36:645-7. 2004
  26. ncbi request reprint Epidemiology of non-dialysis-requiring chronic kidney disease and cardiovascular disease
    Alan S Go
    Division of Research, Kaiser Permanente of Northern California, Oakland, CA 94612 2304, USA
    Curr Opin Nephrol Hypertens 15:296-302. 2006
    ..To review recent literature about the relationship between non-dialysis-requiring chronic kidney disease and cardiovascular disease as well as possible explanatory factors...
  27. ncbi request reprint GFR, body mass index, and low high-density lipoprotein concentration in adults with and without CKD
    Joan C Lo
    Division of Research, Kaiser Permanente Northern California, Oakland, CA 94612, USA
    Am J Kidney Dis 50:552-8. 2007
    ..Low high-density lipoprotein (HDL) cholesterol level is common in patients with chronic kidney disease, but associations between severity of chronic kidney disease, obesity, and HDL level have not been well defined...
  28. ncbi request reprint Epidemiology and adverse cardiovascular risk profile of diagnosed polycystic ovary syndrome
    Joan C Lo
    Division of Research, Kaiser Permanente of Northern California, 2000 Broadway Street, 2nd Floor, Oakland, CA 94612 2304, USA
    J Clin Endocrinol Metab 91:1357-63. 2006
    ..Polycystic ovary syndrome (PCOS) is associated with menstrual and reproductive abnormalities, insulin resistance, and obesity...
  29. pmc Duration of lactation is associated with lower prevalence of the metabolic syndrome in midlife--SWAN, the study of women's health across the nation
    Kavitha T Ram
    Department of Obstetrics and Gynecology, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Am J Obstet Gynecol 198:268.e1-6. 2008
    ..The objective of the study was to evaluate whether lactation duration is associated with lower prevalence of metabolic syndrome (MetSyn) in midlife, parous women...