Research Topics
| Bernard LoSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Clinical decision-making: physicians' preferences and experiencesElizabeth Murray
Department of Primary Care and Population Sciences, Royal Free and University College Medical School at University College London, Archway Campus, Highgate Hill, London N19 5LW, UK
BMC Fam Pract 8:10. 2007..In addition we sought to determine physician perceptions of the availability of time in visits, and their role in encouraging patients to look for health information...
Uses and abuses of prescription drug information in pharmacy benefits management programsB Lo
Center for AIDS Prevention Studies, and the Division of General Internal Medicine, University of California, San Francisco, USA
JAMA 283:801-6. 2000....- Responding to requests regarding prayer and religious ceremonies by patients near the end of life and their familiesBernard Lo
Program in Medical Ethics, Division of General Internal Medicine, University of California, San Francisco, USA
J Palliat Med 6:409-15. 2003..Physicians can respond to requests and respect patients' spiritual needs in ways that may deepen the therapeutic doctor-patient relationship, without compromising their own religious and spiritual beliefs or professional roles... 
Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloningBernard Lo
Program in Medical Ethics, Department of Medicine, The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA
Cell Stem Cell 6:16-20. 2010..Professional standards and laws that ban human reproductive cloning by somatic cell nuclear transfer should be revised to also forbid it by other methods, such as iPSCs via tetraploid complementation...- Professionalism in the age of computerised medical recordsB Lo
Program in Medical Ethics, Division of General Internal Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA 94143 0903, USA
Singapore Med J 47:1018-22. 2006..In the interim, society will need to rely on physicians' professionalism to minimise the risks of electronic medical records and to ensure that the benefits outweigh the risks... - Research with vulnerable participantsBernard Lo
Program in Medical Ethics, University of California, San Francisco, USA
J Clin Ethics 15:55-60. 2004 - Resuscitating advance directivesBernard Lo
Program in Medical Ethics and the Division of General Internal Medicine, The University of California, San Francisco, USA
Arch Intern Med 164:1501-6. 2004..These reforms will encourage discussions between patients and physicians about advance directives and may lead to more informed decisions near the end of life... - Informed consent in human oocyte, embryo, and embryonic stem cell researchBernard Lo
Program in Medical Ethics and the Division of General Internal Medicine, Department of Medicine, University of California at San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0903, USA
Fertil Steril 82:559-63. 2004..Treating assisted reproduction technology physicians can help with the consent process, provided that they are not involved in the research... - A new era in the ethics of human embryonic stem cell researchBernard Lo
Program in Medical Ethics and Division of General Internal Medicine, University of California San Francisco, San Francisco, California, USA
Stem Cells 23:1454-9. 2005..Lack of attention to the special ethical concerns raised by clinical trials of hESC transplantation and their implications for the derivation of new hESC lines may undermine or delay progress toward stem cell therapies... - Advance care planningBernard Lo
the Program in Medical Ethics, The Division of General Internal Medicine, Department of Medicine at the University of California, San Francisco, USA
Am J Geriatr Cardiol 13:316-20. 2004..Physicians can improve discussions about advance directives by asking the patient who should serve as proxy and by ascertaining the patient's values and general preferences before discussing specific clinical situations... - Palliative sedation in dying patients: "we turn to it when everything else hasn't worked"Bernard Lo
Program in Medical Ethics and the Division of General Internal Medicine in the Department of Medicine at the University of California San Francisco, USA
JAMA 294:1810-6. 2005..Because cases involving palliative sedation are emotionally stressful, the patient, family, and health care workers can all benefit from talking about the complex medical, ethical, and emotional issues they raise... - HIPAA and patient care: the role for professional judgmentBernard Lo
Program in Medical Ethics and Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA 94143 0903, USA
JAMA 293:1766-71. 2005..Physicians should work with risk managers and practice administrators to develop policies that promote good communication in patient care, while taking appropriate steps to protect patient privacy... - Clinical decision making during public health emergencies: ethical considerationsBernard Lo
Division of General Internal Medicine, University of California, San Francisco, CA 94143 0903, USA
Ann Intern Med 143:493-8. 2005..Before an emergency occurs, physicians should think through how they will respond to foreseeable dilemmas arising when patients disagree with public health recommendations... 
Establishing ethical trials for treatment and prevention of AIDS in developing countriesBernard Lo
Program in Medical Ethics, University of California, 521 Parnassus Avenue, San Francisco CA 94143-0903, USA
BMJ 327:337-9. 2003- Discussing religious and spiritual issues at the end of life: a practical guide for physiciansBernard Lo
JAMA 287:749-54. 2002..By responding to patients' spiritual and religious concerns and needs, physicians may help them find comfort and closure near the end of life... - Commentary: Conflict of interest policies: an opportunity for the medical profession to take the leadBernard Lo
Program in Medical Ethics, Division of General Internal Medicine, and Department of Medicine, University of California San Francisco, San Francisco, California 94143 0903, USA
Acad Med 85:9-11. 2010..The author concludes that these articles show that physician leaders, AHCs, and professional societies can continue to take the lead by developing, implementing, enforcing, evaluating, and improving thoughtful and effective COI policies... - Conflict-of-interest policies for investigators in clinical trialsB Lo
Medical Ethics, Center for AIDS Prevention Studies, University of California at San Francisco, USA
N Engl J Med 343:1616-20. 2000..There is substantial concern that financial conflicts of interest on the part of investigators conducting clinical trials may compromise the well-being of research subjects... - Oversight of quality improvement: focusing on benefits and risksBernard Lo
Division of General Internal Medicine, University of California, San Francisco 94143, USA
Arch Intern Med 163:1481-6. 2003..We propose a protocol for independent review of QI projects and patient consent that will protect subjects from serious harm while encouraging QI projects that will substantially benefit participants and pose only minimal risk... - Clinical trials in stem cell transplantation: guidelines for scientific and ethical reviewBernard Lo
Program in Medical Ethics and Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0903, USA
Clin Trials 5:517-22. 2008..Transplantation of cells derived through the manipulation of pluripotent stem cells may involve great uncertainty and the possibility of serious risks... - Ethical issues in early detection of HIV infection to reduce vertical transmissionB Lo
the Center for AIDS Prevention Studies, the Program in Medical Ethics, and the Division of General Internal Medicine, University of California San Francisco, USA
J Acquir Immune Defic Syndr 25:S136-43. 2000.... - Medicine. Consent from donors for embryo and stem cell researchBernard Lo
Program in Medical Ethics, School of Medicine at the University of California, San Francisco, CA 94143, USA
Science 301:921. 2003..Some gamete donors who are willing to help women and couples bear children may object to the use of their genetic materials for certain types of research... - Hope, truth, and preparing for death: perspectives of surrogate decision makersLatifat Apatira
University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143, USA
Ann Intern Med 149:861-8. 2008..Although many physicians worry that openly discussing a poor prognosis will cause patients and families to lose hope, surrogate decision makers' perspectives on this topic are largely unknown... - Untapped potential: IRB guidance for the ethical research use of stored biological materialsLeslie E Wolf
Program in Medical Ethics, University of California-San Francisco, USA
IRB 26:1-8. 2004 - Life support for patients without a surrogate decision maker: who decides?Douglas B White
University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143 0903, USA
Ann Intern Med 147:34-40. 2007..Physicians in intensive care units have withdrawn life support in incapacitated patients who lack surrogate decision makers and advance directives, yet little is known about how often this occurs or under what circumstances... - Importing human pluripotent stem cell lines derived at another institution: tailoring review to ethical concernsBernard Lo
Program in Medical Ethics, University of California San Francisco, San Francisco, CA 94143, USA
Cell Stem Cell 4:115-23. 2009..To maintain public trust, research institutions need to justify why they allow researchers to use lines whose derivation would not have been permitted locally... - Are physicians' recommendations to limit life support beneficial or burdensome? Bringing empirical data to the debateDouglas B White
Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, CA 94143, USA
Am J Respir Crit Care Med 180:320-5. 2009..Although there is a growing belief that physicians should routinely provide a recommendation to surrogates during deliberations about withdrawing life support, there is a paucity of empirical data on surrogates' perspectives on this topic... - The language of prognostication in intensive care unitsDouglas B White
Program in Medical Ethics, Department of Medicine, University of California, San Francisco, CA, USA
Med Decis Making 30:76-83. 2010..Rationale. Although misunderstandings about prognosis are common in intensive care units (ICUs), little is known about how physicians actually communicate prognostic information... - The end of therapeutic privilege?Nicole Sirotin
General Internal Medicine Primary Care Residency Program, The Division of General Internal Medicine, and the Department of Medicine at the University of California San Francisco, USA
J Clin Ethics 17:312-6. 2006 - Who should receive life support during a public health emergency? Using ethical principles to improve allocation decisionsDouglas B White
Program in Medical Ethics, School of Medicine, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0903, USA
Ann Intern Med 150:132-8. 2009..We discuss strategies to engage the public in setting the priorities that will guide allocation of scarce life-sustaining treatments during a public health emergency... - The certificate of confidentiality application: a view from the NIH InstitutesLeslie E Wolf
Program in Medical Ethics, University of California-San Francisco, CA, USA
IRB 26:14-8. 2004 - 'She gave it her best shot right away': patient experiences of biomedical and patient-centered communicationSara L Swenson
Program in Medical Ethics at the University of California, Box 0320, 400 Parnassus Avenue, San Francisco, CA 94143 0320, USA
Patient Educ Couns 61:200-11. 2006..We investigated patient responses to videotaped doctor-patient vignettes to ascertain what they liked about patient-centered and biomedical communication... - Prognostication during physician-family discussions about limiting life support in intensive care unitsDouglas B White
Division of Pulmonary and Critical Care Medicine, Program in Medical Ethics, Department of Medicine, University of California, San Francisco, USA
Crit Care Med 35:442-8. 2007.... - Surrogate decision-makers' perspectives on discussing prognosis in the face of uncertaintyLeah R Evans
Division of Pulmonary and Critical Care Medicine, University of California School of Medicine, San Francisco, California 94143 0903, USA
Am J Respir Crit Care Med 179:48-53. 2009..Many physicians are reluctant to discuss a patient's prognosis when there is significant prognostic uncertainty... - The obligation to provide antiretroviral treatment in HIV prevention trialsBernard Lo
Program in Medical Ethics, Center for AIDS Prevention Studies and Division of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA
AIDS 21:1229-31. 2007..Such an assurance should be done in a way that also improves access to ART for others in the country. US funds for ART in poor countries from the PEPFAR should be available to all countries that host HIV prevention and clinical trials... - Decisions to limit life-sustaining treatment for critically ill patients who lack both decision-making capacity and surrogate decision-makersDouglas B White
Division of Pulmonary and Critical Care Medicine, University of California, San Francisco School of Medicine, San Francisco, CA, USA
Crit Care Med 34:2053-9. 2006..Decisions to limit life support were generally made by physicians without judicial or institutional review. Further research and debate are needed to develop optimal decision-making strategies for these difficult cases... - Institutional review board guidance on pediatric research: missed opportunitiesLeslie E Wolf
Program in Medical Ethics, Center for AIDS Prevention Studies, San Francisco, CA 94143, USA
J Pediatr 147:84-9. 2005..To examine whether and how institutional review boards (IRBs) are using their web-sites to provide guidance to investigators conducting pediatric research... - The Wendland case--withdrawing life support from incompetent patients who are not terminally illBernard Lo
University of California at San Francisco, San Francisco, CA 94143-0903, USA
N Engl J Med 346:1489-93. 2002 - NBAC recommendations on oversight of human subject researchBernard Lo
Program in Medical Ethics, Division of General Internal Medicine, University of California, San Francisco, USA
Seton Hall Law Rev 32:493-512. 2003 - Navigating language barriers under difficult circumstancesYael Schenker
University of California, San Francisco, California 94143, USA
Ann Intern Med 149:264-9. 2008..This conceptual and practical approach can help clinicians to improve the quality of care provided to patients with limited English proficiency... - Legal barriers to implementing recommendations for universal, routine prenatal HIV testingLeslie E Wolf
Program in Medical Ethics, Center for AIDS Prevention Studies, Division of General Internal Medicine, University of California, San Francisco, USA
J Law Med Ethics 32:137-47. 2004 - Ethical issues in stem cell researchBernard Lo
University of California San Francisco Program in Medical Ethics, San Francisco, California 94143, USA
Endocr Rev 30:204-13. 2009..This article provides a critical analysis of these issues and how they are addressed in current policies... - Responsible oversight of human stem cell research: the California Institute for Regenerative Medicine's medical and ethical standardsGeoffrey P Lomax
California Institute for Regenerative Medicine, San Francisco, California, United States of America
PLoS Med 4:e114. 2007 - Key clinical, ethical, and policy issues in the evaluation of the safety and effectiveness of solid organ transplantation in HIV-infected patientsMichelle E Roland
Positive Health Program Department of Medicine University of California, San Francisco Ward 84, San Francisco General Hospital 995 Potrero Ave San Francisco, CA 94110, USA
Arch Intern Med 163:1773-8. 2003 - Historical perspective and evolving concerns for human researchBernard Lo
Program in Medical Ethics, Department of Medicine, University of California San Francisco San Francisco, California, USA
Cancer Treat Res 132:1-10. 2007 - The challenges of IRB review and human subjects protections in practice-based researchLeslie E Wolf
Program in Medical Ethics, the Center for AIDS Prevention Studies, and the Division of General Internal Medicine, San Francisco, California 94143 0903, USA
Med Care 40:521-9. 2002..Practice-based research investigators and professional societies can facilitate this process by helping to define and implement the appropriate training for busy practice-based research clinicians and office staff... - Patient-centered communication: do patients really prefer it?Sara L Swenson
Program in Medical Ethics, Division of General Internal Medicine, University of California San Francisco, CA 94143 0320, USA
J Gen Intern Med 19:1069-79. 2004..To investigate patient preferences for a patient-centered or a biomedical communication style... - Human subjects issues and IRB review in practice-based researchLeslie E Wolf
University of California, San Francisco, San Francisco, California 94143 0903, USA
Ann Fam Med 3:S30-7. 2005..This article explores the challenges that practice-based research networks (PBRNs) face with respect to the regulatory requirements for institutional review board (IRB) review and the protection of human subjects in research... - Lessons from an HIV transmission pairFrederick M Hecht
Division of HIV/AIDS, Department of Medicine, University of California, San Francisco, CA 94110, USA
J Infect Dis 195:1239-41. 2007 - Clinical trial design issues raised during recombinant DNA advisory committee review of gene transfer protocolsTiffany Scharschmidt
School of Medicine and Program in Medical Ethics, and Division of General Internal Medicine, University of California San Francisco, San Francisco, CA 94143-0903, USA
Hum Gene Ther 17:448-54. 2006..Such attention might help strengthen clinical trial protocols, shorten the protocol development process, and enhance the protection of research participants... - Use of videos by directors of medical ethics coursesDelaney Ruston
Department of General Internal Medicine, University of California, San Francisco, USA
J Clin Ethics 15:201-8. 2004 - Medical students' experiences with medical errors: an analysis of medical student essaysWilliam Martinez
University of California San Francisco Berkeley Joint Medical Program, San Francisco, California, USA
Med Educ 42:733-41. 2008..This study aimed to examine medical students' experiences with medical errors... - IRB Chairs' Perspectives on Genomics Research Involving Stored Biological Materials: Ethical Concerns and Proposed SolutionsLeslie E Wolf
University of California, San Francisco
J Empir Res Hum Res Ethics 3:99-111. 2008.... - Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trialSusan P Buchbinder
HIV Research Section, San Francisco Department of Public Health, San Francisco, CA, USA
Lancet 372:1881-93. 2008..The Step Study directly assessed the efficacy of a cell-mediated immunity vaccine to protect against HIV-1 infection or change in early plasma HIV-1 levels... - Ethics and the practice of brain scienceBernard Lo
Program in Medical Ethics, University of California, San Francisco, CA, USA
Cerebrum 4:64-6. 2002 - How pediatricians counsel parents when no "best-choice" management exists: lessons to be learned from hypoplastic left heart syndromeAlexander A Kon
Department of Pediatrics and Program in Bioethics, University of California, Davis, Sacramento 95817, USA
Arch Pediatr Adolesc Med 158:436-41. 2004..Three mutually exclusive management options exist: the Norwood palliative procedure, cardiac transplantation, and comfort care without surgical intervention... - The impact of health information on the Internet on health care and the physician-patient relationship: national U.S. survey among 1.050 U.S. physiciansElizabeth Murray
Royal Free and University College School of Medicine at University College London, Department of Primary Care and Population Sciences, London, UK
J Med Internet Res 5:e17. 2003..We studied physicians' experience of patients looking for health information on the Internet and their perceptions of the impact of this information on the physician-patient relationship, health care, and workload... - Informed consent in HIV researchLeslie E Wolf
Focus 19:5-6. 2004 - Strengthening community consultation in critical care and emergency researchBernard Lo
Crit Care Med 34:2236-8. 2006 - How do patients view the role of the primary care physician in inpatient care?Milena Hruby
Dis Mon 48:230-8. 2002..Systems should be established to facilitate communication between in patient and primary care physicians, and between PCPs and patients... - Strategies for culturally effective end-of-life careLaVera M Crawley
Stanford University Center for Biomedical Ethics, 701 Welch Road, Suite 1105, Palo Alto, CA 94304, USA
Ann Intern Med 136:673-9. 2002..Attention to cultural difference enables the physician to provide comprehensive and compassionate palliative care at the end of life... - Clinical decision-making: Patients' preferences and experiencesElizabeth Murray
Department of Primary Care and Population Sciences, Royal Free and University College Medical School at University College London, Archway Campus, Highgate Hill, London N19 5LW, United Kingdom
Patient Educ Couns 65:189-96. 2007.... - Establishing procedures for institutional oversight of stem cell researchPatricia Zettler
Stanford Law School, Stanford, CA, USA
Acad Med 82:6-10. 2007..The SCRO neither replaces nor duplicates review by the IRB and institutional animal care and use committees. Other AHCs can draw on the UCSF experience when developing their own policies and procedures for stem cell research oversight... - Choices physicians would make if they were the parents of a child with hypoplastic left heart syndromeAlexander A Kon
Section of Pediatric Critical Care Medicine, University of California-Davis, Ticon II, Room 228, 2516 Stockton Boulevard, Sacramento, CA 95817, USA
Am J Cardiol 91:1506-9, A9. 2003 - The impact of health information on the internet on the physician-patient relationship: patient perceptionsElizabeth Murray
Department of Health Career Scientist, Department of Primary Care and Population Sciences, Royal Free and University College School of Medicine at University College London, England
Arch Intern Med 163:1727-34. 2003.... - Direct-to-consumer advertising: public perceptions of its effects on health behaviors, health care, and the doctor-patient relationshipElizabeth Murray
Department of Primary Care and Population Sciences, Royal Free and University College School of Medicine at University College London, United Kingdom
J Am Board Fam Pract 17:6-18. 2004.... - Direct-to-consumer advertising: physicians' views of its effects on quality of care and the doctor-patient relationshipElizabeth Murray
Department of Primary Care and Population Sciences, Royal Free and University College School of Medicine at University College London, United Kingdom
J Am Board Fam Pract 16:513-24. 2003..The objective of the study was to determine physicians' views of the effects of Direct-to-Consumer Advertising (DTCA) on health service utilization, quality of care, and the doctor-patient relationship... - Directions in research on spiritual and religious isues for imprroving palliative careBernard Lo
Palliat Support Care 1:3-5. 2003 - The roles and experiences of nonaffiliated and non-scientist members of institutional review boardsSohini Sengupta
Department of Social Medicine, University of North Carolina at Chapel Hill, NC 27599 7164, USA
Acad Med 78:212-8. 2003..This study investigated the experiences of IRB lay members from leading academic medical institutions in the United States and presents their recommendations for future education and training... - Ethical and policy implications of hospitalist systemsBernard Lo
Dis Mon 48:281-90. 2002..By setting such standards and monitoring performance, hospitalist systems can improve the quality of care and reassure patients...