Bernard Lo

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Ethical issues in stem cell research
    Bernard Lo
    University of California San Francisco Program in Medical Ethics, San Francisco, California 94143, USA
    Endocr Rev 30:204-13. 2009
  2. doi request reprint Importing human pluripotent stem cell lines derived at another institution: tailoring review to ethical concerns
    Bernard Lo
    Program in Medical Ethics, University of California San Francisco, San Francisco, CA 94143, USA
    Cell Stem Cell 4:115-23. 2009
  3. ncbi request reprint Informed consent in human oocyte, embryo, and embryonic stem cell research
    Bernard Lo
    Program in Medical Ethics and the Division of General Internal Medicine, Department of Medicine, University of California at San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0903, USA
    Fertil Steril 82:559-63. 2004
  4. pmc Hope, truth, and preparing for death: perspectives of surrogate decision makers
    Latifat Apatira
    University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143, USA
    Ann Intern Med 149:861-8. 2008
  5. ncbi request reprint Life support for patients without a surrogate decision maker: who decides?
    Douglas B White
    University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143 0903, USA
    Ann Intern Med 147:34-40. 2007
  6. ncbi request reprint Untapped potential: IRB guidance for the ethical research use of stored biological materials
    Leslie E Wolf
    Program in Medical Ethics, University of California San Francisco, USA
    IRB 26:1-8. 2004
  7. ncbi request reprint A new era in the ethics of human embryonic stem cell research
    Bernard Lo
    Program in Medical Ethics and Division of General Internal Medicine, University of California San Francisco, San Francisco, California, USA
    Stem Cells 23:1454-9. 2005
  8. doi request reprint Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning
    Bernard Lo
    Program in Medical Ethics, Department of Medicine, The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA
    Cell Stem Cell 6:16-20. 2010
  9. pmc Are physicians' recommendations to limit life support beneficial or burdensome? Bringing empirical data to the debate
    Douglas B White
    Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, CA 94143, USA
    Am J Respir Crit Care Med 180:320-5. 2009
  10. pmc The language of prognostication in intensive care units
    Douglas B White
    Program in Medical Ethics, Department of Medicine, University of California, San Francisco, CA, USA
    Med Decis Making 30:76-83. 2010

Detail Information

Publications35

  1. pmc Ethical issues in stem cell research
    Bernard Lo
    University of California San Francisco Program in Medical Ethics, San Francisco, California 94143, USA
    Endocr Rev 30:204-13. 2009
    ..This article provides a critical analysis of these issues and how they are addressed in current policies...
  2. doi request reprint Importing human pluripotent stem cell lines derived at another institution: tailoring review to ethical concerns
    Bernard Lo
    Program in Medical Ethics, University of California San Francisco, San Francisco, CA 94143, USA
    Cell Stem Cell 4:115-23. 2009
    ..To maintain public trust, research institutions need to justify why they allow researchers to use lines whose derivation would not have been permitted locally...
  3. ncbi request reprint Informed consent in human oocyte, embryo, and embryonic stem cell research
    Bernard Lo
    Program in Medical Ethics and the Division of General Internal Medicine, Department of Medicine, University of California at San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0903, USA
    Fertil Steril 82:559-63. 2004
    ..Treating assisted reproduction technology physicians can help with the consent process, provided that they are not involved in the research...
  4. pmc Hope, truth, and preparing for death: perspectives of surrogate decision makers
    Latifat Apatira
    University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143, USA
    Ann Intern Med 149:861-8. 2008
    ..Although many physicians worry that openly discussing a poor prognosis will cause patients and families to lose hope, surrogate decision makers' perspectives on this topic are largely unknown...
  5. ncbi request reprint Life support for patients without a surrogate decision maker: who decides?
    Douglas B White
    University of California, San Francisco, and San Francisco General Hospital, San Francisco, California 94143 0903, USA
    Ann Intern Med 147:34-40. 2007
    ..Physicians in intensive care units have withdrawn life support in incapacitated patients who lack surrogate decision makers and advance directives, yet little is known about how often this occurs or under what circumstances...
  6. ncbi request reprint Untapped potential: IRB guidance for the ethical research use of stored biological materials
    Leslie E Wolf
    Program in Medical Ethics, University of California San Francisco, USA
    IRB 26:1-8. 2004
  7. ncbi request reprint A new era in the ethics of human embryonic stem cell research
    Bernard Lo
    Program in Medical Ethics and Division of General Internal Medicine, University of California San Francisco, San Francisco, California, USA
    Stem Cells 23:1454-9. 2005
    ..Lack of attention to the special ethical concerns raised by clinical trials of hESC transplantation and their implications for the derivation of new hESC lines may undermine or delay progress toward stem cell therapies...
  8. doi request reprint Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning
    Bernard Lo
    Program in Medical Ethics, Department of Medicine, The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA
    Cell Stem Cell 6:16-20. 2010
    ..Professional standards and laws that ban human reproductive cloning by somatic cell nuclear transfer should be revised to also forbid it by other methods, such as iPSCs via tetraploid complementation...
  9. pmc Are physicians' recommendations to limit life support beneficial or burdensome? Bringing empirical data to the debate
    Douglas B White
    Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, CA 94143, USA
    Am J Respir Crit Care Med 180:320-5. 2009
    ..Although there is a growing belief that physicians should routinely provide a recommendation to surrogates during deliberations about withdrawing life support, there is a paucity of empirical data on surrogates' perspectives on this topic...
  10. pmc The language of prognostication in intensive care units
    Douglas B White
    Program in Medical Ethics, Department of Medicine, University of California, San Francisco, CA, USA
    Med Decis Making 30:76-83. 2010
    ..Rationale. Although misunderstandings about prognosis are common in intensive care units (ICUs), little is known about how physicians actually communicate prognostic information...
  11. pmc Who should receive life support during a public health emergency? Using ethical principles to improve allocation decisions
    Douglas B White
    Program in Medical Ethics, School of Medicine, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0903, USA
    Ann Intern Med 150:132-8. 2009
    ..We discuss strategies to engage the public in setting the priorities that will guide allocation of scarce life-sustaining treatments during a public health emergency...
  12. pmc Informed consent for innovative surgery: a survey of patients and surgeons
    Susan J Lee Char
    Department of Surgery, University of California, San Francisco, CA 94143 0790, USA
    Surgery 153:473-80. 2013
    ..To provide surgeons with more specific guidance, we wanted to determine what information patients and surgeons consider essential to disclose before an innovative surgical procedure...
  13. pmc Surrogate decision-makers' perspectives on discussing prognosis in the face of uncertainty
    Leah R Evans
    Division of Pulmonary and Critical Care Medicine, University of California School of Medicine, San Francisco, California 94143 0903, USA
    Am J Respir Crit Care Med 179:48-53. 2009
    ..Many physicians are reluctant to discuss a patient's prognosis when there is significant prognostic uncertainty...
  14. doi request reprint Commentary: Conflict of interest policies: an opportunity for the medical profession to take the lead
    Bernard Lo
    Program in Medical Ethics, Division of General Internal Medicine, and Department of Medicine, University of California San Francisco, San Francisco, California 94143 0903, USA
    Acad Med 85:9-11. 2010
    ..The author concludes that these articles show that physician leaders, AHCs, and professional societies can continue to take the lead by developing, implementing, enforcing, evaluating, and improving thoughtful and effective COI policies...
  15. ncbi request reprint Institutional review board guidance on pediatric research: missed opportunities
    Leslie E Wolf
    Program in Medical Ethics, Center for AIDS Prevention Studies, San Francisco, CA 94143, USA
    J Pediatr 147:84-9. 2005
    ..To examine whether and how institutional review boards (IRBs) are using their web-sites to provide guidance to investigators conducting pediatric research...
  16. pmc When previously expressed wishes conflict with best interests
    Alexander K Smith
    Division of Geriatrics, University of California, San Francisco, San Francisco, CA 94941, USA
    JAMA Intern Med 173:1241-5. 2013
    ....
  17. pmc Human subjects issues and IRB review in practice-based research
    Leslie E Wolf
    University of California, San Francisco, San Francisco, California 94143 0903, USA
    Ann Fam Med 3:S30-7. 2005
    ..This article explores the challenges that practice-based research networks (PBRNs) face with respect to the regulatory requirements for institutional review board (IRB) review and the protection of human subjects in research...
  18. ncbi request reprint Prognostication during physician-family discussions about limiting life support in intensive care units
    Douglas B White
    Division of Pulmonary and Critical Care Medicine, Program in Medical Ethics, Department of Medicine, University of California, San Francisco, USA
    Crit Care Med 35:442-8. 2007
    ....
  19. doi request reprint Clinical trials in stem cell transplantation: guidelines for scientific and ethical review
    Bernard Lo
    Program in Medical Ethics and Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0903, USA
    Clin Trials 5:517-22. 2008
    ..Transplantation of cells derived through the manipulation of pluripotent stem cells may involve great uncertainty and the possibility of serious risks...
  20. ncbi request reprint Navigating language barriers under difficult circumstances
    Yael Schenker
    University of California, San Francisco, California 94143, USA
    Ann Intern Med 149:264-9. 2008
    ..This conceptual and practical approach can help clinicians to improve the quality of care provided to patients with limited English proficiency...
  21. ncbi request reprint Lessons from an HIV transmission pair
    Frederick M Hecht
    Division of HIV AIDS, Department of Medicine, University of California, San Francisco, CA 94110, USA
    J Infect Dis 195:1239-41. 2007
  22. doi request reprint Ethical considerations in HIV cure research: points to consider
    Bernard Lo
    University of California, San Francisco, California, USA
    Curr Opin HIV AIDS 8:243-9. 2013
    ..Research directed toward an HIV cure presents ethical as well as scientific challenges...
  23. doi request reprint An educational intervention to improve resident comfort with communication at the end of life
    Leah Smith
    University of California, San Francisco, San Francisco, California 94143, USA
    J Palliat Med 16:54-9. 2013
    ..Utilizing facilitated, case-based, peer interactions, we sought to assess the feasibility and impact of a novel resident curriculum in end-of-life education...
  24. ncbi request reprint The certificate of confidentiality application: a view from the NIH Institutes
    Leslie E Wolf
    Program in Medical Ethics, University of California San Francisco, CA, USA
    IRB 26:14-8. 2004
  25. ncbi request reprint HIPAA and patient care: the role for professional judgment
    Bernard Lo
    Program in Medical Ethics and Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA 94143 0903, USA
    JAMA 293:1766-71. 2005
    ..Physicians should work with risk managers and practice administrators to develop policies that promote good communication in patient care, while taking appropriate steps to protect patient privacy...
  26. ncbi request reprint The obligation to provide antiretroviral treatment in HIV prevention trials
    Bernard Lo
    Program in Medical Ethics, Center for AIDS Prevention Studies and Division of General Internal Medicine, University of California San Francisco, San Francisco, CA, USA
    AIDS 21:1229-31. 2007
    ..Such an assurance should be done in a way that also improves access to ART for others in the country. US funds for ART in poor countries from the PEPFAR should be available to all countries that host HIV prevention and clinical trials...
  27. ncbi request reprint Clinical trial design issues raised during recombinant DNA advisory committee review of gene transfer protocols
    Tiffany Scharschmidt
    School of Medicine and Program in Medical Ethics, and Division of General Internal Medicine, University of California San Francisco, San Francisco, CA 94143 0903, USA
    Hum Gene Ther 17:448-54. 2006
    ..Such attention might help strengthen clinical trial protocols, shorten the protocol development process, and enhance the protection of research participants...
  28. ncbi request reprint Medicine. Consent from donors for embryo and stem cell research
    Bernard Lo
    Program in Medical Ethics, School of Medicine at the University of California, San Francisco, CA 94143, USA
    Science 301:921. 2003
    ..Some gamete donors who are willing to help women and couples bear children may object to the use of their genetic materials for certain types of research...
  29. ncbi request reprint Decisions to limit life-sustaining treatment for critically ill patients who lack both decision-making capacity and surrogate decision-makers
    Douglas B White
    Division of Pulmonary and Critical Care Medicine, University of California, San Francisco School of Medicine, San Francisco, CA, USA
    Crit Care Med 34:2053-9. 2006
    ..We sought to determine how often such patients are admitted to the ICU of a metropolitan hospital and how end-of-life decisions are made for them...
  30. ncbi request reprint Clinical decision making during public health emergencies: ethical considerations
    Bernard Lo
    Division of General Internal Medicine, University of California, San Francisco, CA 94143 0903, USA
    Ann Intern Med 143:493-8. 2005
    ..Before an emergency occurs, physicians should think through how they will respond to foreseeable dilemmas arising when patients disagree with public health recommendations...
  31. pmc Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial
    Susan P Buchbinder
    HIV Research Section, San Francisco Department of Public Health, San Francisco, CA, USA
    Lancet 372:1881-93. 2008
    ..The Step Study directly assessed the efficacy of a cell-mediated immunity vaccine to protect against HIV-1 infection or change in early plasma HIV-1 levels...
  32. ncbi request reprint Historical perspective and evolving concerns for human research
    Bernard Lo
    Program in Medical Ethics, Department of Medicine, University of California San Francisco San Francisco, California, USA
    Cancer Treat Res 132:1-10. 2007
  33. ncbi request reprint Legal barriers to implementing recommendations for universal, routine prenatal HIV testing
    Leslie E Wolf
    Program in Medical Ethics, Center for AIDS Prevention Studies, Division of General Internal Medicine, University of California, San Francisco, USA
    J Law Med Ethics 32:137-47. 2004
  34. doi request reprint Medical students' experiences with medical errors: an analysis of medical student essays
    William Martinez
    University of California San Francisco Berkeley Joint Medical Program, San Francisco, California, USA
    Med Educ 42:733-41. 2008
    ..This study aimed to examine medical students' experiences with medical errors...
  35. ncbi request reprint Ethics and the practice of brain science
    Bernard Lo
    Program in Medical Ethics, University of California, San Francisco, CA, USA
    Cerebrum 4:64-6. 2002