Alexandra Livingstone

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. doi request reprint Unravelling the mechanisms of help for CD8+ T cell responses
    Alexandra M Livingstone
    David H Smith Center for Vaccine Biology and Immunology, Aab Institute of Biomedical Sciences, Rochester, NY, USA
    Immunol Res 45:209-17. 2009
  2. ncbi request reprint Dendritic cells need T cell help to prime cytotoxic T cell responses to strong antigens
    A M Livingstone
    Department of Biology, Imperial College of Science, Technology and Medicine, London, GB
    Eur J Immunol 29:2826-34. 1999
  3. ncbi request reprint Peptide-pulsed splenic dendritic cells prime long-lasting CD8(+) T cell memory in the absence of cross-priming by host APC
    Alexandra M Livingstone
    Basel Institute for Immunology, Basel, Switzerland
    Eur J Immunol 32:281-90. 2002
  4. ncbi request reprint Cutting edge: CD4+ T cell help can be essential for primary CD8+ T cell responses in vivo
    Jyh Chiang E Wang
    David H Smith Center for Vaccine Biology and Immunology, Aab Institute of Biomedical Sciences, and Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 171:6339-43. 2003
  5. ncbi request reprint Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing
    Jennifer E Snyder
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, New York, USA
    Nat Med 9:231-5. 2003
  6. ncbi request reprint Dendritic cells: the immune information management experts
    Tim R Mosmann
    Nat Immunol 5:564-6. 2004

Research Grants

  1. CD8+ T Cell Memory Primed By Dendritic Cells
    Alexandra Livingstone; Fiscal Year: 2005

Collaborators

  • F Eun Hyung Lee
  • Tim R Mosmann
  • Jyh Chiang E Wang
  • Jennifer E Snyder
  • William J Bowers
  • Howard J Federoff

Detail Information

Publications6

  1. doi request reprint Unravelling the mechanisms of help for CD8+ T cell responses
    Alexandra M Livingstone
    David H Smith Center for Vaccine Biology and Immunology, Aab Institute of Biomedical Sciences, Rochester, NY, USA
    Immunol Res 45:209-17. 2009
    ....
  2. ncbi request reprint Dendritic cells need T cell help to prime cytotoxic T cell responses to strong antigens
    A M Livingstone
    Department of Biology, Imperial College of Science, Technology and Medicine, London, GB
    Eur J Immunol 29:2826-34. 1999
    ..The observation that highly immunogenic minor-incompatible DC failed to prime MHC class II-deficient mice suggests that in the absence of inflammatory signals, even strong antigens cannot stimulate CD8+ T cell responses without help...
  3. ncbi request reprint Peptide-pulsed splenic dendritic cells prime long-lasting CD8(+) T cell memory in the absence of cross-priming by host APC
    Alexandra M Livingstone
    Basel Institute for Immunology, Basel, Switzerland
    Eur J Immunol 32:281-90. 2002
    ..Thus peptide-pulsed DC can prime long-lasting CD8(+) memory responses without any requirement for cross-priming by other APC...
  4. ncbi request reprint Cutting edge: CD4+ T cell help can be essential for primary CD8+ T cell responses in vivo
    Jyh Chiang E Wang
    David H Smith Center for Vaccine Biology and Immunology, Aab Institute of Biomedical Sciences, and Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Immunol 171:6339-43. 2003
    ..Thus, the primary in vivo CD8(+) T cell response depends absolutely on help from CD4(+) T cells in our experimental system...
  5. ncbi request reprint Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing
    Jennifer E Snyder
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, New York, USA
    Nat Med 9:231-5. 2003
    ..The simultaneous enumeration of cytokine-secreting and cytotoxic cells should be invaluable for ex vivo analysis of immune responses during infection and autoimmunity...
  6. ncbi request reprint Dendritic cells: the immune information management experts
    Tim R Mosmann
    Nat Immunol 5:564-6. 2004

Research Grants4

  1. CD8+ T Cell Memory Primed By Dendritic Cells
    Alexandra Livingstone; Fiscal Year: 2005
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