Chad A Livasy

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi request reprint Identification of a basal-like subtype of breast ductal carcinoma in situ
    Chad A Livasy
    Department of Pathology and Lab Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Hum Pathol 38:197-204. 2007
  2. ncbi request reprint Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
    Chad A Livasy
    Department of Pathology and Lab Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Mod Pathol 19:264-71. 2006
  3. ncbi request reprint The clinical significance of a negative loop electrosurgical cone biopsy for high-grade dysplasia
    Chad A Livasy
    Department of Pathology and Lab Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7525, USA
    Obstet Gynecol 104:250-4. 2004
  4. ncbi request reprint Focal adhesion kinase overexpression in endometrial neoplasia
    Chad A Livasy
    Department of Pathology, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Appl Immunohistochem Mol Morphol 12:342-5. 2004
  5. ncbi request reprint EGFR expression and HER2/neu overexpression/amplification in endometrial carcinosarcoma
    Chad A Livasy
    Department of Pathology and Lab Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Gynecol Oncol 100:101-6. 2006
  6. doi request reprint Local control following single-dose intraoperative radiotherapy prior to surgical excision of early-stage breast cancer
    Randall J Kimple
    Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Ann Surg Oncol 18:939-45. 2011
  7. ncbi request reprint High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype
    Amy L Lark
    Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Mod Pathol 18:1289-94. 2005
  8. ncbi request reprint Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
    Lisa A Carey
    Division of Hematology Oncology, School of Public Health, Department of Epidemiology, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC 27599 7305, USA
    JAMA 295:2492-502. 2006
  9. pmc Cosmetic outcomes for accelerated partial breast irradiation before surgical excision of early-stage breast cancer using single-dose intraoperative radiotherapy
    Randall J Kimple
    Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Int J Radiat Oncol Biol Phys 79:400-7. 2011
  10. ncbi request reprint Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis
    Harry M Lightfoot
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Breast Cancer Res Treat 88:109-16. 2004

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Identification of a basal-like subtype of breast ductal carcinoma in situ
    Chad A Livasy
    Department of Pathology and Lab Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Hum Pathol 38:197-204. 2007
    ..0001), p53 overexpression (P < .0001), and elevated Ki-67 index (P < .0001). These studies demonstrate the presence of a basal-like in situ carcinoma, a potential precursor lesion to invasive basal-like carcinoma...
  2. ncbi request reprint Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
    Chad A Livasy
    Department of Pathology and Lab Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Mod Pathol 19:264-71. 2006
    ..These findings should further assist in the identification of basal-like carcinomas in clinical specimens, facilitating treatment and epidemiologic studies of this tumor subtype...
  3. ncbi request reprint The clinical significance of a negative loop electrosurgical cone biopsy for high-grade dysplasia
    Chad A Livasy
    Department of Pathology and Lab Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7525, USA
    Obstet Gynecol 104:250-4. 2004
    ..We sought to estimate the incidence and clinical significance of a negative therapeutic loop electrosurgical excision procedure (LEEP) and to evaluate patient specimens for limiting histologic features associated with a negative LEEP...
  4. ncbi request reprint Focal adhesion kinase overexpression in endometrial neoplasia
    Chad A Livasy
    Department of Pathology, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Appl Immunohistochem Mol Morphol 12:342-5. 2004
    ..FAK overexpression in endometrial carcinoma correlates with higher FIGO grade and p53 overexpression...
  5. ncbi request reprint EGFR expression and HER2/neu overexpression/amplification in endometrial carcinosarcoma
    Chad A Livasy
    Department of Pathology and Lab Medicine, University of North Carolina, Chapel Hill, NC 27599 7525, USA
    Gynecol Oncol 100:101-6. 2006
    ..The aim of this study was to evaluate for HER2 and EGFR expression in cases of endometrial carcinosarcoma...
  6. doi request reprint Local control following single-dose intraoperative radiotherapy prior to surgical excision of early-stage breast cancer
    Randall J Kimple
    Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Ann Surg Oncol 18:939-45. 2011
    ..This study details our completed, single-institution trial...
  7. ncbi request reprint High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype
    Amy L Lark
    Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Mod Pathol 18:1289-94. 2005
    ..The presence of strong FAK expression in many high grade, estrogen- and progesterone-negative breast carcinomas indicates that FAK may be an attractive target for therapeutic intervention...
  8. ncbi request reprint Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
    Lisa A Carey
    Division of Hematology Oncology, School of Public Health, Department of Epidemiology, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC 27599 7305, USA
    JAMA 295:2492-502. 2006
    ..Gene expression analysis has identified several breast cancer subtypes, including basal-like, human epidermal growth factor receptor-2 positive/estrogen receptor negative (HER2+/ER-), luminal A, and luminal B...
  9. pmc Cosmetic outcomes for accelerated partial breast irradiation before surgical excision of early-stage breast cancer using single-dose intraoperative radiotherapy
    Randall J Kimple
    Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Int J Radiat Oncol Biol Phys 79:400-7. 2011
    ..Determine cosmetic outcome and toxicity profile of intraoperative radiation delivered before tumor excision for patients with early-stage breast cancer...
  10. ncbi request reprint Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis
    Harry M Lightfoot
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Breast Cancer Res Treat 88:109-16. 2004
    ..0001) and IDC (p = 0.02). We conclude that FAK overexpression in preinvasive, DCIS tumors precedes tumor cell invasion or metastasis, suggesting that FAK may function as a survival signal and be an early event in breast tumorigenesis...
  11. pmc The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study
    Kathleen Conway
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Breast Cancer Res 7:R871-80. 2005
    ..This mutation was initially reported in one-third of hyperplastic benign breast lesions, although several recent studies failed to detect it in benign or malignant breast tissues...
  12. pmc Molecular characterization of human breast tumor vascular cells
    Rajendra Bhati
    Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Am J Pathol 172:1381-90. 2008
    ..Therefore, these genetic markers may serve as potential targets for the development of angiogenesis inhibitors...
  13. pmc Methylation-dependent silencing of CST6 in primary human breast tumors and metastatic lesions
    Ashley G Rivenbark
    Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Exp Mol Pathol 83:188-97. 2007
    ..Overall, the results of the current investigation suggest that methylation-dependent epigenetic silencing of CST6 represents an important mechanism for loss of CST6 during breast tumorigenesis and/or progression to metastasis...
  14. ncbi request reprint Overexpression of the receptor tyrosine kinase Tie-1 intracellular domain in breast cancer
    Xi Hui Yang
    Department of Surgery, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA
    Tumour Biol 24:61-9. 2003
    ..The purpose of this study was to determine the cell types expressing Tie-1, whether Tie-1 is expressed in tumor cells, and to examine the regulation of Tie-1 in breast cancer...
  15. doi request reprint Use of the ThinPrep method in bile duct brushings: analysis of morphologic parameters associated with malignancy and determination of interobserver reliability
    Michael S Waugh
    Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Diagn Cytopathol 36:651-6. 2008
    ..The relatively high proportion of benign cases thought to be diagnostic of malignancy by at least one reviewer argues for a consensus approach to this diagnosis...
  16. ncbi request reprint Miliary pulmonary metastases from a clinically occult pleural mesothelioma
    Chad A Livasy
    Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, 27599 7525, USA
    Ann Diagn Pathol 7:249-53. 2003
    ..Metastatic mesothelioma is a consideration for metastatic pulmonary tumors of unknown origin...
  17. ncbi request reprint Overexpression of focal adhesion kinase in primary colorectal carcinomas and colorectal liver metastases: immunohistochemistry and real-time PCR analyses
    Amy L Lark
    Department of Pathology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599 7210, USA
    Clin Cancer Res 9:215-22. 2003
    ..To determine whether FAK expression is up-regulated in colorectal cancer, we analyzed FAK mRNA and protein levels in primary colorectal tumors and colorectal liver metastases...
  18. ncbi request reprint Feasibility of breast preserving therapy with single fraction in situ radiotherapy delivered intraoperatively
    David W Ollila
    Department of Surgery, UNC Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, 3010 Old Clinic Building, CB 7213, Chapel Hill, NC 27599 7213, USA
    Ann Surg Oncol 14:660-9. 2007
    ..We adapted the technique of Veronesi to deliver IORT prior to tumor excision to improve delivery to the region at risk and reduce the volume of normal tissue irradiated...
  19. doi request reprint Effect of breast compression on lesion characteristic visibility with diffraction-enhanced imaging
    Laura S Faulconer
    Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Acad Radiol 17:433-40. 2010
    ..Because DEI possesses inherently superior contrast mechanisms, the current study assesses the effect of breast compression on lesion characteristic visibility with DEI imaging of breast specimens...