Research Topics
| Youcheng LiuSummaryAffiliation: University of Kentucky Country: USA Publications
Research Grants
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Detail Information
Publications
Skin exposure to aliphatic polyisocyanates in the auto body repair and refinishing industry: a qualitative assessmentYoucheng Liu
Occupational and Environmental Medicine Program, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06510, USA
Ann Occup Hyg 51:429-39. 2007....
Skin exposure to aliphatic polyisocyanates in the auto body repair and refinishing industry: III. A personal exposure algorithmYoucheng Liu
Department of Preventive Medicine and Environmental Health, College of Public Health, University of Kentucky, 121 Washington Avenue, Lexington, KY 40536, USA
Ann Occup Hyg 53:33-40. 2009..The relationship between skin and respiratory exposure metrics was also evaluated...- Outdoor and indoor air pollution and COPD-related diseases in high- and low-income countriesY Liu
Department of Preventive Medicine and Environmental Health, University of Kentucky College of Public Health, Lexington, Kentucky 40536, USA
Int J Tuberc Lung Dis 12:115-27. 2008..A joint effort from both society and governments is needed for these endeavors... - Respiratory protection from isocyanate exposure in the autobody repair and refinishing industryYoucheng Liu
Occupational and Environmental Medicine Program, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA
J Occup Environ Hyg 3:234-49. 2006.... - Isocyanate exposures in autobody shop work: the SPRAY studyJudy Sparer
Yale Occupational and Environmental Medicine Program, Yale School of Medicine, New Haven, CT 06510, USA
J Occup Environ Hyg 1:570-81. 2004..Despite improvements in autobody shop materials, practices, and controls, there are still opportunities for substantial exposures to isocyanates... - Estrogens: trophic and protective factors in the adult brainP M Wise
Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky 40536 0298, USA
Front Neuroendocrinol 22:33-66. 2001..This area of research demands attention since estradiol may be an important therapeutic agent in the maintenance of normal neural function during aging and after injury... - Cholestatic properties and hepatic transport of steroid glucuronidesM Vore
Department of Pharmacology, University of Kentucky, Lexington 40536 0305, USA
Drug Metab Rev 29:183-203. 1997..Nevertheless, these studies implicate a role of P-glycoprotein in the regulation of bile secretion by the liver... - A magnetostatic-coupling based remote query sensor for environmental monitoringC A Grimes
Department of Electrical Engineering, The University of Kentucky, Lexington, KY 40506, USA
J Phys D Appl Phys 32:1329-35. 1999.... - Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaineJ Turchan
Department of Neurology, University of Kentucky, Lexington, USA
BMC Neurosci 2:3. 2001..We determined the combined effects of dopaminergic drugs, methamphetamine, or cocaine with neurotoxic HIV proteins, gp120 and Tat... - Urinary hexane diamine to assess respiratory exposure to hexamethylene diisocyanate aerosol: a human inhalation studyYoucheng Liu
Occupational and Environmental Medicine Program, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06510 2283, USA
Int J Occup Environ Health 10:262-71. 2004..1, respectively, at 4, 9, and 18 hours post exposure. Considerable individual variability was found. Urinary HDA can assess acute respiratory exposure to HDI aerosol, but may have limited use as a biomarker of exposure in the workplace... 
Farmer exposure to organic solvents during the maintenance and repair of farm machinery: a pilot studyTerry L Bunn
Kentucky Injury Prevention and Research Center, University of Kentucky College of Public Health, Lexington, Kentucky 40504, USA
Am J Ind Med 52:973-81. 2009..The maintenance/repair of farm machinery is a common farming activity. Dermal exposure to organic solvents has not been well documented. A pilot study was conducted to characterize exposure to organic solvents...- Heat-stable antigen is a costimulatory molecule for CD4 T cell growthY Liu
Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06510
J Exp Med 175:437-45. 1992..Gene transfer experiments directly demonstrate that this protein has costimulatory activity. Thus, heat-stable antigen meets the criteria for a costimulator of T cell clonal expansion... - High glucose impairs voltage-gated K(+) channel current in rat small coronary arteriesY Liu
Department of Internal Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
Circ Res 89:146-52. 2001..We speculate that this O(2)(.-)-induced impairment may reduce vasodilator responsiveness in the coronary circulation of subjects with coronary disease or its risk factors... - Co-stimulation of murine CD4 T cell growth: cooperation between B7 and heat-stable antigenY Liu
Section of Immunobiology, Yale University School of Medicine, New Haven
Eur J Immunol 22:2855-9. 1992..These results demonstrate that functionally defined co-stimulation involves at least B7 and HSA and suggest that signals delivered by B7 and HSA synergize in promoting T cell growth... - A transcription map of the major histocompatibility complex (MHC) class I regionJ R Gruen
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, 06520, USA
Genomics 36:70-85. 1996..We also detected several previously undefined genes that are specifically expressed in cells of the immune system, indicating a more complex role of the MHC in the immune response than has been appreciated... - Polyisocyanates in occupational environments: a critical review of exposure limits and metricsDhimiter Bello
University of Massachusetts Lowell, Work Environment Department, KI 200, One University Avenue, Lowell, MA 01854, USA
Am J Ind Med 46:480-91. 2004..However, with multiple different measurement metrics in use, comparison of isocyanate exposure data between studies and development of occupational exposure limits (OELs) for polyisocyanates is difficult... - Comparison of task-based exposure metrics for an epidemiologic study of isocyanate inhalation exposures among autobody shop workersSusan R Woskie
Department of Work Environment, University of Massachusetts at Lowell, Lowell, Massachusetts 01854, USA susan
J Occup Environ Hyg 5:588-98. 2008..K. Health and Safety Executive occupational exposure limit (OEL) for total NCO of 20 microg/m(3). When respirator use was incorporated, all personal daily exposures were below the U.K. OEL... - Skin exposure to isocyanates: reasons for concernDhimiter Bello
Exposure, Epidemiology and Risk Program, Harvard School of Public Health, Boston, Massachusetts 01854, USA
Environ Health Perspect 115:328-35. 2007..In this review we evaluate the potential role of skin exposure in the development of isocyanate asthma... - Slow curing of aliphatic polyisocyanate paints in automotive refinishing: a potential source for skin exposureDhimiter Bello
Department of Work Environment, University of Massachusetts Lowell, Lowell, Massachusetts 01854, USA
J Occup Environ Hyg 4:406-11. 2007..Unbound isocyanates may remain on the surface of painted car parts for prolonged periods (days to weeks) after dried. Such surfaces are an under-recognized potential source of skin exposure to autobody workers... - Skin exposure to aliphatic polyisocyanates in the auto body repair and refinishing industry: II. A quantitative assessmentDhimiter Bello
Department of Work Environment, School of Health and Environment, University of Massachusetts Lowell, One University Avenue, Lowell, MA 01854, USA
Ann Occup Hyg 52:117-24. 2008..Skin exposure to isocyanates, in addition to respiratory exposures, may contribute to sensitization and asthma. Quantitative skin exposure data are scarce and quantitative methods limited... - Where there's smoke there's lung diseaseYoucheng Liu
Thorax 62:838-9. 2007 - Estimation of personal exposures to particulate matter and metals in boiler overhaul workYoucheng Liu
Department of Environmental Health, Harvard University School of Public Health, Boston, Massachusetts, USA corrected
J Occup Environ Med 47:68-78. 2005..We sought to develop an algorithm and estimate unmeasured exposures to particulate matter (PM) and metals in an epidemiologic study of boilermakers... - An FTIR investigation of isocyanate skin absorption using in vitro guinea pig skinDhimiter Bello
Harvard School of Public Health, Exposure, Epidemiology and Risk Program, Landmark Center, West 404F, 401 Park Drive, Boston, MA 02215, USA
J Environ Monit 8:523-9. 2006..The significance of these findings and their implications for dermal exposure sampling and isocyanate skin decontamination are discussed... - Exposure to fuel-oil ash and welding emissions during the overhaul of an oil-fired boilerYoucheng Liu
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
J Occup Environ Hyg 2:435-43. 2005..Fuel-oil ash was a major contributor to boilermakers' exposure to PM(10) and metals. Vanadium concentrations sometimes exceeded the 2003 American Conference of Governmental Industrial Hygienists (ACGIH) threshold limit value... - A laboratory investigation of the effectiveness of various skin and surface decontaminants for aliphatic polyisocyanatesDhimiter Bello
University of Massachusetts Lowell, Work Environment Department, KI 200, One University Ave, Lowell, MA 01854, USA
J Environ Monit 7:716-21. 2005..In vitro testing using animal skins and in vivo testing with field workers are being conducted to further assess the efficiency and identify related determinants...
Research Grants
- Isocyanate Exposure Intervention Study in Body ShopsYoucheng Liu; Fiscal Year: 2004..abstract_text> ..