Yijun Liu

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint The temporal response of the brain after eating revealed by functional MRI
    Y Liu
    Department of Psychiatry and Brain Institute, University of Florida, Gainesville 32610, USA
    Nature 405:1058-62. 2000
  2. pmc Microstructure abnormalities in adolescents with internet addiction disorder
    Kai Yuan
    School of Life Sciences and Technology, Life Sciences Research Center, Xidian University, Xi an, Shaanxi, China
    PLoS ONE 6:e20708. 2011
  3. pmc The temporal-spatial encoding of acupuncture effects in the brain
    Wei Qin
    Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China
    Mol Pain 7:19. 2011
  4. pmc Acupuncture modulates temporal neural responses in wide brain networks: evidence from fMRI study
    Lijun Bai
    Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China
    Mol Pain 6:73. 2010
  5. pmc FMRI connectivity analysis of acupuncture effects on an amygdala-associated brain network
    Wei Qin
    Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, Beijing, PR China
    Mol Pain 4:55. 2008
  6. ncbi request reprint Food addiction and obesity: evidence from bench to bedside
    Yijun Liu
    Division of Global Tobacco, Alcohol, Obesity and Health Research, University of Florida, Department of Psychiatry and McKnight Brain Institute, PO Box 100256, Gainesville, FL 32610 0256, USA
    J Psychoactive Drugs 42:133-45. 2010
  7. doi request reprint Divergent neural processes specific to the acute and sustained phases of verum and SHAM acupuncture
    Jixin Liu
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, Shaanxi, China
    J Magn Reson Imaging 33:33-40. 2011
  8. ncbi request reprint Time-varied characteristics of acupuncture effects in fMRI studies
    Lijun Bai
    Life Science Research Center, School of Electronic Engineering, Xidian University, Shaanxi, China
    Hum Brain Mapp 30:3445-60. 2009
  9. pmc Interaction between dysfunctional connectivity at rest and heroin cues-induced brain responses in male abstinent heroin-dependent individuals
    Jixin Liu
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, Shaanxi, China
    PLoS ONE 6:e23098. 2011
  10. ncbi request reprint Altered small-world brain functional networks and duration of heroin use in male abstinent heroin-dependent individuals
    Kai Yuan
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an 710071, China
    Neurosci Lett 477:37-42. 2010

Collaborators

Detail Information

Publications46

  1. ncbi request reprint The temporal response of the brain after eating revealed by functional MRI
    Y Liu
    Department of Psychiatry and Brain Institute, University of Florida, Gainesville 32610, USA
    Nature 405:1058-62. 2000
    ..Moreover, this study provides a neuroimaging basis for detecting dynamic processes without prior knowledge of their timing, such as the acute effects of medication and nutrition in the brain...
  2. pmc Microstructure abnormalities in adolescents with internet addiction disorder
    Kai Yuan
    School of Life Sciences and Technology, Life Sciences Research Center, Xidian University, Xi an, Shaanxi, China
    PLoS ONE 6:e20708. 2011
    ....
  3. pmc The temporal-spatial encoding of acupuncture effects in the brain
    Wei Qin
    Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, Beijing, 100190, China
    Mol Pain 7:19. 2011
    ..Functional acupoint specificity is crucial to the clinical efficacy of acupuncture treatment, such as pain relief. Whether acupuncture needling at a peripheral acupoint produces distinct patterns of brain responses remains controversial...
  4. pmc Acupuncture modulates temporal neural responses in wide brain networks: evidence from fMRI study
    Lijun Bai
    Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China
    Mol Pain 6:73. 2010
    ....
  5. pmc FMRI connectivity analysis of acupuncture effects on an amygdala-associated brain network
    Wei Qin
    Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, Beijing, PR China
    Mol Pain 4:55. 2008
    ..Recently, increasing evidence has indicated that the primary acupuncture effects are mediated by the central nervous system. However, specific brain networks underpinning these effects remain unclear...
  6. ncbi request reprint Food addiction and obesity: evidence from bench to bedside
    Yijun Liu
    Division of Global Tobacco, Alcohol, Obesity and Health Research, University of Florida, Department of Psychiatry and McKnight Brain Institute, PO Box 100256, Gainesville, FL 32610 0256, USA
    J Psychoactive Drugs 42:133-45. 2010
    ..The acquired drive for great food and relative weakness of the satiety signal would cause an imbalance between the drive and hunger/reward centers in the brain and their regulation...
  7. doi request reprint Divergent neural processes specific to the acute and sustained phases of verum and SHAM acupuncture
    Jixin Liu
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, Shaanxi, China
    J Magn Reson Imaging 33:33-40. 2011
    ..To discuss which brain region potentially functioned and switched between the immediate and delayed response of acupuncture...
  8. ncbi request reprint Time-varied characteristics of acupuncture effects in fMRI studies
    Lijun Bai
    Life Science Research Center, School of Electronic Engineering, Xidian University, Shaanxi, China
    Hum Brain Mapp 30:3445-60. 2009
    ..These findings may pose great implications for the design and interpretation of a range of acupuncture neuroimaging studies...
  9. pmc Interaction between dysfunctional connectivity at rest and heroin cues-induced brain responses in male abstinent heroin-dependent individuals
    Jixin Liu
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, Shaanxi, China
    PLoS ONE 6:e23098. 2011
    ..Yet few studies considered the relevance of resting state dysfunctional connectivity to task-related neural activity in the same chronic heroin user (CHU)...
  10. ncbi request reprint Altered small-world brain functional networks and duration of heroin use in male abstinent heroin-dependent individuals
    Kai Yuan
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an 710071, China
    Neurosci Lett 477:37-42. 2010
    ..Our findings suggested that there is abnormal functional organization in heroin-dependent individuals and that the duration of heroin use is a critical factor leading to the altered brain connectivity...
  11. doi request reprint Distinct resting-state brain activities in heroin-dependent individuals
    Yi Zhang
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, Shaanxi 710071, China
    Brain Res 1402:46-53. 2011
    ..The implications from our study may help explain the behavioral and neuropsychological deficits in heroin-dependent individuals and shed light on the mechanisms underlying heroin addiction...
  12. pmc Altered functional brain networks in Prader-Willi syndrome
    Yi Zhang
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, Shaanxi, China
    NMR Biomed 26:622-9. 2013
    ....
  13. ncbi request reprint Sylvian fissure morphology in Prader-Willi syndrome and early-onset morbid obesity
    Jennifer L Miller
    Departments of Pediatrics, University of Florida, College of Medicine, Gainesville, Florida 32610 0296, USA
    Genet Med 9:536-43. 2007
    ..We hypothesized that similar perisylvian abnormalities may exist in both disorders...
  14. doi request reprint Comparison of visual cortical activations induced by electro-acupuncture at vision and nonvision-related acupoints
    Yi Zhang
    Life Science Research Center, School of Electronic Engineering, Xidian University, Xi an, Shaanxi 710071, China
    Neurosci Lett 458:6-10. 2009
    ..Our results revealed that acupuncture at vision and nonvision-related acupoints can induce similar activations in spatial distribution but different modulation effects temporally...
  15. doi request reprint Gray matter deficits and resting-state abnormalities in abstinent heroin-dependent individuals
    Kai Yuan
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an 710071, China
    Neurosci Lett 482:101-5. 2010
    ..Our findings demonstrated that long heroin dependence impairs the right DLPFC in heroin-dependent individuals, including structural deficits and resting-state functional impairments...
  16. doi request reprint An fMRI study of acupuncture using independent component analysis
    Yi Zhang
    Life Science Research Center, School of Electronic Engineering, Xidian University, Xi an, Shaanxi 710071, China
    Neurosci Lett 449:6-9. 2009
    ..Furthermore, the distinction between needle stimulation and the resting state indicated that there existed different functional brain networks. These results also portray time variability during the course of acupuncture...
  17. doi request reprint The hybrid GLM-ICA investigation on the neural mechanism of acupoint ST36: an fMRI study
    Peng Liu
    Life Science Research Center, School of Life Science and Technology, Xidian University, Xi an, Shaanxi 710071, China
    Neurosci Lett 479:267-71. 2010
    ..Our findings suggested that the analgesia effects of ST36 integrated sophisticated physiological and psychological procedures. In addition, our results have shed light on methodology in acupuncture research...
  18. doi request reprint Distinct brain networks for time-varied characteristics of acupuncture
    Jixin Liu
    School of Electronic Engineering, Xidian University, Xi an, Shaanxi 710071, China
    Neurosci Lett 468:353-8. 2010
    ..Our findings provide direct evidence that the post-needling resting state contains acupuncture-related effects that are due to the slow-acting nature of acupuncture...
  19. pmc Enhanced activation of reward mediating prefrontal regions in response to food stimuli in Prader-Willi syndrome
    Jennifer L Miller
    Department of Pediatrics, University of Florida, College of Medicine, Gainesville, Florida, USA
    J Neurol Neurosurg Psychiatry 78:615-9. 2007
    ..We hypothesised that the abnormal appetite in PWS results from aberrant reward processing of food stimuli in these neural pathways...
  20. doi request reprint Investigating the effects of low dose alcohol on neural timing using functional MRI
    Nelson J Klahr
    Department of Psychiatry and McKnight Brain Institute, University of Florida, Gainesville, Florida 32610 0256, USA
    J Magn Reson Imaging 34:1045-52. 2011
    ..To examine human brain function related to the perception of short time intervals before and after ingesting a low dosage of alcohol (0.25 g/kg)...
  21. pmc Assessing cue-induced brain response as a function of abstinence duration in heroin-dependent individuals: an event-related fMRI study
    Qiang Li
    Department of Radiology, Tangdu Hospital, The Fourth Military Medical University, Xi an, China
    PLoS ONE 8:e62911. 2013
    ..These findings suggest that long-term abstinence may be useful for heroin-dependent patients to diminish their saliency value of heroin-related cues and possibly lower the relapse vulnerability to some extent...
  22. pmc Top-down regulation of default mode activity in spatial visual attention
    Xiaotong Wen
    J Crayton Pruitt Family Department of Biomedical Engineering and Department of Psychiatry and McKnight Brain Institute, University of Florida, Gainesville, Florida 32611, USA
    J Neurosci 33:6444-53. 2013
    ....
  23. ncbi request reprint Pituitary abnormalities in Prader-Willi syndrome and early onset morbid obesity
    Jennifer L Miller
    Department of Pediatrics, University of Florida, College of Medicine, Gainesville, Florida 32610 0296, USA
    Am J Med Genet A 146:570-7. 2008
    ....
  24. pmc Early childhood obesity is associated with compromised cerebellar development
    Jennifer L Miller
    Department of Pediatrics, Division of Pediatric Endocrinology, University of Florida, College of Medicine, Gainesville, Florida 32610 0296, USA
    Dev Neuropsychol 34:272-83. 2009
    ..PWS and controls vs. EMO). As both conditions are characterized by early-onset obesity and slowed cognitive development, these results raise the possibility that early childhood obesity retards both cerebellar and cognitive development...
  25. ncbi request reprint Food addiction and neuroimaging
    Yi Zhang
    Department of Psychiatry, McKnight Brain Institute, University of Florida, 100 Newell Drive, PO Box 100256, Gainesville, FL 32610, USA
    Curr Pharm Des 17:1149-57. 2011
    ....
  26. pmc Cortical thickness abnormalities in late adolescence with online gaming addiction
    Kai Yuan
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, Shaanxi, China
    PLoS ONE 8:e53055. 2013
    ..The findings in the current study suggested that the cortical thickness abnormalities of these regions may be implicated in the underlying pathophysiology of online gaming addiction...
  27. doi request reprint Acupuncture modulates spontaneous activities in the anticorrelated resting brain networks
    Lijun Bai
    Life Science Research Center, School of Life Science and Technology, Xidian University, Xi an, China
    Brain Res 1279:37-49. 2009
    ....
  28. doi request reprint Dysfunctional connectivity patterns in chronic heroin users: an fMRI study
    Jixin Liu
    Life Science Research Center, School of Electronic Engineering, Xidian University, Xi an, Shaanxi 710071, China
    Neurosci Lett 460:72-7. 2009
    ..This dysfunctional brain connectivity may contribute to decrease self-control, impaired inhibitory function as well deficits in stress regulation in chronic heroin users...
  29. ncbi request reprint Interaction of satiety and reward response to food stimulation
    G Andrew James
    University of Florida College of Medicine, Department of Psychiatry, Gainesville, FL 32610 0256, USA
    J Addict Dis 23:23-37. 2004
    ..We review the interaction between central satiety signals and reward responses to food stimuli and discuss the implications of this research for understanding the causes of obesity...
  30. doi request reprint Neural specificity of acupuncture stimulation from support vector machine classification analysis
    Ting Xue
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an 710071, China
    Magn Reson Imaging 29:943-50. 2011
    ..Moreover, we also proved that GLM analysis is prone to be susceptible to errors and is not appropriate for detecting neural response patterns evoked by acupuncture stimulation...
  31. doi request reprint Mapping a multidimensional emotion in response to television commercials
    Jon D Morris
    College of Journalism and Communications, University of Florida, Gainesville, Florida 32611, USA
    Hum Brain Mapp 30:789-96. 2009
    ..These findings suggest a dimensional approach of constructing emotional changes in the brain and provide a better understanding of human behavior in response to advertising stimuli...
  32. doi request reprint Obesity as an addiction: Why do the obese eat more?
    Karen M von Deneen
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi an, China
    Maturitas 68:342-5. 2011
    ..Functional magnetic resonance imaging (fMRI) has been applied to study why obese individuals overeat. Introduction of this technology will serve as a means in paving the way for new weight loss drugs...
  33. pmc Dissociated responses in the amygdala and orbitofrontal cortex to bottom-up and top-down components of emotional evaluation
    Paul Wright
    Department of Psychiatry, University of Florida, Gainesville, Florida, USA
    Neuroimage 39:894-902. 2008
    ..Activation of ventromedial prefrontal cortex and modulation of amygdalar response were not observed, and future studies may investigate whether these effects are contingent upon anticipation or cognitive set...
  34. ncbi request reprint A full-size MRI-compatible keyboard response system
    George Andrew James
    Department of Neuroscience, University of Florida, 100 S Newell Drive L4 100, PO Box 100256, Gainesville, FL 32610 0256, USA
    Neuroimage 25:328-31. 2005
    ..Implementing this MRI-compatible keyboard allows the collection of motor responses from complex manual behaviors (i.e., typing) and thus represents a valuable tool for functional MRI (fMRI) studies...
  35. ncbi request reprint Obesity in China: what are the causes?
    Karen M von Deneen
    Life Sciences Research Center, School of Life Sciences and Technology, Xidian University
    Curr Pharm Des 17:1132-9. 2011
    ..We attempt to discuss obesity issues particularly in the Han Chinese population ranging from children, adolescents, adults to geriatrics...
  36. doi request reprint Altered effective connectivity of the default mode network in resting-state amnestic type mild cognitive impairment
    Hao Yan
    School of Psychology, Shaanxi Normal University, Xi an, China
    J Int Neuropsychol Soc 19:400-9. 2013
    ..These findings may elucidate the dysfunctional processes in brain networks of aMCI patients, highlighting the importance of connectivity changes in the pathophysiology of aMCI...
  37. ncbi request reprint Causal interactions in attention networks predict behavioral performance
    Xiaotong Wen
    J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611, USA
    J Neurosci 32:1284-92. 2012
    ....
  38. ncbi request reprint Intracranial abnormalities detected by three-dimensional magnetic resonance imaging in Prader-Willi syndrome
    Jennifer L Miller
    Department of Pediatrics, University of Florida, Gainesville, Florida 32610 0296, USA
    Am J Med Genet A 143:476-83. 2007
    ..The specific mechanisms underlying these neuropathological abnormalities and their correlation with the clinical phenotype remain to be elucidated...
  39. ncbi request reprint Reward circuitry dopaminergic activation regulates food and drug craving behavior
    Kenneth Blum
    Department of Psychiatry, and McKnight Brain Institute, University of Florida, College of Medicine, Gainesville, Florida, USA
    Curr Pharm Des 17:1158-67. 2011
    ..Finally, utilizing the long term dopaminergic activation approach will ultimately lead to a common safe and effective modality to treat RDS behaviors including aberrant food and drug craving behaviors...
  40. ncbi request reprint Neurocognitive findings in Prader-Willi syndrome and early-onset morbid obesity
    Jennifer Miller
    Department of Pediatrics and the Center for Mammalian Genetics, University of Florida, College of Medicine, Gainesville, Florida 32610 0296, USA
    J Pediatr 149:192-8. 2006
    ..To examine whether early-onset morbid obesity is associated with cognitive impairment, neuropathologic changes, and behavioral problems...
  41. ncbi request reprint Neutral faces activate the amygdala during identity matching
    Paul Wright
    Department of Psychiatry, McKnight Brain Institute, University of Florida, 100 Newell Drive, PO Box 100256, Gainesville, 32610 0256, USA
    Neuroimage 29:628-36. 2006
    ..We concluded that the amygdalar response to face matching is driven at least in part by relevance detection, independent of emotion processing, although there appears to be additional emotion-specific processing at the left amygdala...
  42. pmc Detecting directional influence in fMRI connectivity analysis using PCA based Granger causality
    Zhenyu Zhou
    Pediatric Brain Imaging Laboratory, Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Brain Res 1289:22-9. 2009
    ..These results indicate that using PCA may improve upon application of existing GCMs in study of human brain effective connectivity...
  43. ncbi request reprint Brain activation by disgust-inducing pictures in obsessive-compulsive disorder
    Nathan A Shapira
    Department of Psychiatry, College of Medicine, University of Florida, Gainesville, Florida, USA
    Biol Psychiatry 54:751-6. 2003
    ..There is growing interest in the role of disgust in the pathogenesis of obsessive-compulsive disorder (OCD)...
  44. ncbi request reprint Modulation of neural connectivity during tongue movement and reading
    Alex G He
    Department of Psychiatry and McKnight Brain Institute, University of Florida, Gainesville, Florida 32610, USA
    Hum Brain Mapp 18:222-32. 2003
    ....
  45. pmc Arithmetic processing in the brain shaped by cultures
    Yiyuan Tang
    Institute of Neuroinformatics and Laboratory for Brain and Mind, Dalian University of Technology, Dalian 116023, China
    Proc Natl Acad Sci U S A 103:10775-80. 2006
    ....
  46. doi request reprint Voxel-based morphometry study on brain structure in children with high-functioning autism
    Xiaoyan Ke
    Key Laboratory of Child Development and Learning Science Southeast University, Ministry of Education, Nanjing Medical University, Nanjing, China
    Neuroreport 19:921-5. 2008
    ..Our findings showed global and regional brain volumes abnormality in high-functioning autism...

Research Grants4

  1. Impaired Brain-Leptin Interaction in Chronic Tobacco Us*
    Yijun Liu; Fiscal Year: 2002
    ..The neural modeling will be accomplished by the task-dependent interregional covariance analysis of fMRI signal in fasting subjects (smokers and controls) during exposure to food-related emotional stimuli before and after eating. ..
  2. Dynamic fMRI Analyses of Hypoglycemia Unawareness
    Yijun Liu; Fiscal Year: 2003
    ..Development of both temporal and spatial reference systems for the in vivo modeling of glycemia regulation and hypoglycemia unawareness. ..
  3. FMRI Analysis of a Neural Network Involved in Depression
    Yijun Liu; Fiscal Year: 2006
    ..Aim 3: to test the working hypothesis that the pregenual cingulate cortex governs selection of salient emotional stimuli. ..
  4. Diffusion Tensor Imaging in Autism
    Yijun Liu; Fiscal Year: 2007
    ....