Xuhui Liu

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint A mouse model of massive rotator cuff tears
    Xuhui Liu
    San Francisco Veterans Affairs Medical Center, Building 2, Room 639, 4150 Clement Street, San Francisco, CA 94121, USA
    J Bone Joint Surg Am 94:e41. 2012
  2. pmc Emerging ideas: matrix metalloproteinase-2 in muscle atrophy
    Xuhui Liu
    San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA
    Clin Orthop Relat Res 469:1797-9. 2011
  3. doi request reprint mTOR regulates fatty infiltration through SREBP-1 and PPARγ after a combined massive rotator cuff tear and suprascapular nerve injury in rats
    Sunil K Joshi
    San Francisco Veterans Affairs Medical Center, Department of Veterans Affairs, University of California, 1500 Owens Avenue, San Francisco, CA 94153, USA
    J Orthop Res 31:724-30. 2013
  4. doi request reprint MRI quantification of fatty infiltration and muscle atrophy in a mouse model of rotator cuff tears
    Sanjum P Samagh
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
    J Orthop Res 31:421-6. 2013
  5. doi request reprint Evaluation of Akt/mTOR activity in muscle atrophy after rotator cuff tears in a rat model
    Xuhui Liu
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, Califronia, USA
    J Orthop Res 30:1440-6. 2012
  6. doi request reprint Muscle degeneration in rotator cuff tears
    Dominique Laron
    Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA 94158, USA
    J Shoulder Elbow Surg 21:164-74. 2012
  7. pmc Differential ubiquitin-proteasome and autophagy signaling following rotator cuff tears and suprascapular nerve injury
    Sunil K Joshi
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, California, 94153 Department of Orthopaedic Surgery, University of California, San Francisco, California, 94158
    J Orthop Res 32:138-44. 2014
  8. ncbi request reprint Role of AP-1 and RE-1 binding sites in matrix metalloproteinase-2 transcriptional regulation in skeletal muscle atrophy
    Xuhui Liu
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, 4150 Clement St, San Francisco, CA 94121, USA
    Biochem Biophys Res Commun 396:219-23. 2010
  9. doi request reprint Role of gelatinases in disuse-induced skeletal muscle atrophy
    Xuhui Liu
    San Francisco Veterans Affairs Medical Center, Department of Veterans Affairs, 4150 Clement Street 112, San Francisco, California 94121, USA
    Muscle Nerve 41:174-8. 2010
  10. pmc Evaluation of cartilage degeneration in a rat model of rotator cuff tear arthropathy
    Erik J Kramer
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA Department of Orthopaedic Surgery, University of California, San Francisco, CA, USA
    J Shoulder Elbow Surg 22:1702-9. 2013

Collaborators

Detail Information

Publications12

  1. doi request reprint A mouse model of massive rotator cuff tears
    Xuhui Liu
    San Francisco Veterans Affairs Medical Center, Building 2, Room 639, 4150 Clement Street, San Francisco, CA 94121, USA
    J Bone Joint Surg Am 94:e41. 2012
    ..The goal of this study was to develop a mouse model of muscle atrophy and fatty infiltration after a rotator cuff tear. We also sought to study the role of denervation on muscle atrophy and fatty infiltration after a rotator cuff tear...
  2. pmc Emerging ideas: matrix metalloproteinase-2 in muscle atrophy
    Xuhui Liu
    San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA
    Clin Orthop Relat Res 469:1797-9. 2011
    ....
  3. doi request reprint mTOR regulates fatty infiltration through SREBP-1 and PPARγ after a combined massive rotator cuff tear and suprascapular nerve injury in rats
    Sunil K Joshi
    San Francisco Veterans Affairs Medical Center, Department of Veterans Affairs, University of California, 1500 Owens Avenue, San Francisco, CA 94153, USA
    J Orthop Res 31:724-30. 2013
    ..Therefore, our study suggests that mTOR signaling mediates rotator cuff fatty infiltration via SREBP-1 and PPARγ. Clinically, our finding may alter current treatment methods to address rotator cuff fatty infiltration...
  4. doi request reprint MRI quantification of fatty infiltration and muscle atrophy in a mouse model of rotator cuff tears
    Sanjum P Samagh
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
    J Orthop Res 31:421-6. 2013
    ..This suggests that MRI is a reliable modality in evaluating the progression of fatty infiltration and muscle atrophy following rotator cuff tears in a small animal model...
  5. doi request reprint Evaluation of Akt/mTOR activity in muscle atrophy after rotator cuff tears in a rat model
    Xuhui Liu
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, Califronia, USA
    J Orthop Res 30:1440-6. 2012
    ....
  6. doi request reprint Muscle degeneration in rotator cuff tears
    Dominique Laron
    Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA 94158, USA
    J Shoulder Elbow Surg 21:164-74. 2012
    ..Understanding these molecular pathways will help guide further research and treatment options that can aim to alter expression of these pathways and improve outcomes after surgical repair of massive rotator cuff tears...
  7. pmc Differential ubiquitin-proteasome and autophagy signaling following rotator cuff tears and suprascapular nerve injury
    Sunil K Joshi
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, California, 94153 Department of Orthopaedic Surgery, University of California, San Francisco, California, 94158
    J Orthop Res 32:138-44. 2014
    ..The findings of this study suggest that protein degradation is the primary factor contributing to atrophy following rotator cuff injury. However, different proteolytic pathways are activated if SSN injury is involved...
  8. ncbi request reprint Role of AP-1 and RE-1 binding sites in matrix metalloproteinase-2 transcriptional regulation in skeletal muscle atrophy
    Xuhui Liu
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, 4150 Clement St, San Francisco, CA 94121, USA
    Biochem Biophys Res Commun 396:219-23. 2010
    ..Novel information gained from this study has improved our understanding of in vivo transcriptional regulation of MMP-2 in skeletal muscle atrophy...
  9. doi request reprint Role of gelatinases in disuse-induced skeletal muscle atrophy
    Xuhui Liu
    San Francisco Veterans Affairs Medical Center, Department of Veterans Affairs, 4150 Clement Street 112, San Francisco, California 94121, USA
    Muscle Nerve 41:174-8. 2010
    ..These findings suggest that gelatinase A, and not gelatinase B, plays a critical role in disuse-induced skeletal muscle atrophy...
  10. pmc Evaluation of cartilage degeneration in a rat model of rotator cuff tear arthropathy
    Erik J Kramer
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA Department of Orthopaedic Surgery, University of California, San Francisco, CA, USA
    J Shoulder Elbow Surg 22:1702-9. 2013
    ..The goal of this study was to assess the utility of this model in investigating cuff tear arthropathy...
  11. doi request reprint A rat model of massive rotator cuff tears
    Xuhui Liu
    Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
    J Orthop Res 29:588-95. 2011
    ..Six weeks after surgery, the average wet weight of supraspinatus and infraspinatus muscles decreased 13.2% and 28.3%, respectively. Significant fat infiltration was only observed in infraspinatus 6 weeks after tendon transection...
  12. ncbi request reprint Matrix metalloproteinase-2 expression and promoter/enhancer activity in skeletal muscle atrophy
    Laura K Skittone
    San Francisco Veterans Affairs Medical Center, 4150 Clement Street 112, San Francisco, California 94121, USA
    J Orthop Res 26:357-63. 2008
    ..These findings show that increased MMP-2 activity in disused atrophic muscle and supporting tissues is regulated, at least in part, by increased MMP-2 promoter/enhancer activity...