Ming Cheh Liu

Summary

Affiliation: University of Texas Health Center
Country: USA

Publications

  1. ncbi Sulfation of nitrotyrosine: biochemistry and functional implications
    Ming Cheh Liu
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, Ohio, USA
    IUBMB Life 59:622-7. 2007
  2. ncbi A novel hydroxysteroid-sulfating cytosolic sulfotransferase, SULT3 ST3, from zebrafish: identification, characterization, and ontogenic study
    Shin Yasuda
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA
    Drug Metab Lett 3:217-27. 2009
  3. doi Identification and characterization of two novel cytosolic sulfotransferases, SULT1 ST7 and SULT1 ST8, from zebrafish
    Tzu An Liu
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA
    Aquat Toxicol 89:94-102. 2008
  4. pmc Identification and characterization of zebrafish SULT1 ST9, SULT3 ST4, and SULT3 ST5
    Yasir I Mohammed
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43614, USA
    Aquat Toxicol 112:11-8. 2012
  5. pmc Sulfation of ractopamine and salbutamol by the human cytosolic sulfotransferases
    Kyounga Ko
    Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Toledo, OH 43614, USA
    J Biochem 152:275-83. 2012
  6. ncbi The use of zebrafish as a model system for investigating the role of the SULTs in the metabolism of endogenous compounds and xenobiotics
    Katsuhisa Kurogi
    Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Toledo, OH, USA and
    Drug Metab Rev 45:431-40. 2013
  7. doi Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: role of the human SULT1A3
    Shin Yasuda
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43614, USA
    Toxicol Appl Pharmacol 251:104-9. 2011
  8. doi Hydroxylated serotonin and dopamine as substrates and inhibitors for human cytosolic SULT1A3
    Shin Yasuda
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, Ohio, USA
    J Neurochem 103:2679-89. 2007
  9. pmc Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs
    Katsuhisa Kurogi
    Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, 3000 Arlington Avenue, Toledo, OH 43614, USA
    Biochem Pharmacol 84:1186-95. 2012
  10. ncbi On the sulfation and methylation of catecholestrogens in human mammary epithelial cells and breast cancer cells
    Ying Hui
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA
    Biol Pharm Bull 31:769-73. 2008

Collaborators

  • Frederick E Williams
  • Tomoko Yasuda
  • Yuh Shyong Yang
  • S Idell
  • Ezdihar Hassoun
  • Michael Brown
  • Masao Yamasaki
  • Makoto Kimura
  • Sreerama Shetty
  • Yoshimitsu Kakuta
  • Matthew D Krasowski
  • Masahito Suiko
  • Yoichi Sakakibara
  • Shin Yasuda
  • Katsuhisa Kurogi
  • Takuya Sugahara
  • Tzu An Liu
  • T Govind Pai
  • Ying Hui
  • Shakhawat Bhuiyan
  • Emi Mishiro
  • Saki Takahashi
  • Kei Ohkimoto
  • Rhodora Snow
  • Zheng Xu
  • Adnan Alazizi
  • Glendora Carter
  • Thirunavukkarasu Velusamy
  • Chau Ching Liu
  • Praveenkumar Shetty
  • Takuyu Hashiguchi
  • Kyounga Ko
  • Garrett Davidson
  • Yasir I Mohammed
  • Jian Fu
  • Kazuo Nishiyama
  • Yashodhar P Bhandary
  • Faye Xu
  • Lanzhuang Chen
  • Jing Hua Lu
  • Ryo Akashi
  • Takehiko Shimohira
  • Bo Shi
  • Yoonjung Lee
  • Yasir Ihsan Mohammed
  • Teng Yan
  • Amani Al Shaban
  • Mei Chen
  • Elisha Injeti
  • Vijayakumar Boggaram
  • Katherine Ann Wall
  • Meredith Burgess
  • Rika Nobe
  • Yi Yong Wu
  • Rashmi S Shetty
  • Haruna Kouriki
  • Xiao Min An
  • Ji Ping Zhang
  • Hai Tao Li
  • Wen Rui Chang
  • A Pavan Kumar
  • Mei Li
  • Paul Collodi
  • Ila Oxendine

Detail Information

Publications47

  1. ncbi Sulfation of nitrotyrosine: biochemistry and functional implications
    Ming Cheh Liu
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, Ohio, USA
    IUBMB Life 59:622-7. 2007
    ..Functional implications of the sulfation of nitrotyrosine are discussed...
  2. ncbi A novel hydroxysteroid-sulfating cytosolic sulfotransferase, SULT3 ST3, from zebrafish: identification, characterization, and ontogenic study
    Shin Yasuda
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA
    Drug Metab Lett 3:217-27. 2009
    ..Collectively, these results suggest a possible involvement of the newly discovered SULT3 ST3 in the metabolism of hydroxysteroids and xenobiotics including drugs in zebrafish...
  3. doi Identification and characterization of two novel cytosolic sulfotransferases, SULT1 ST7 and SULT1 ST8, from zebrafish
    Tzu An Liu
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA
    Aquat Toxicol 89:94-102. 2008
    ..Developmental expression experiments revealed distinct patterns of expression of SULT1 ST7 and SULT1 ST8 during embryonic development and throughout the larval stage onto maturity...
  4. pmc Identification and characterization of zebrafish SULT1 ST9, SULT3 ST4, and SULT3 ST5
    Yasir I Mohammed
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43614, USA
    Aquat Toxicol 112:11-8. 2012
    ..Reverse transcription-polymerase chain reaction (RT-PCR) was performed to examine the expression of these three new zebrafish SULTs at different developmental stages during embryogenesis, through larval development, and on to maturity...
  5. pmc Sulfation of ractopamine and salbutamol by the human cytosolic sulfotransferases
    Kyounga Ko
    Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Toledo, OH 43614, USA
    J Biochem 152:275-83. 2012
    ..Collectively, these results imply that the sulfation mediated by SULT1A3 may play an important role in the metabolism and detoxification of ractopamine and salbutamol...
  6. ncbi The use of zebrafish as a model system for investigating the role of the SULTs in the metabolism of endogenous compounds and xenobiotics
    Katsuhisa Kurogi
    Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Toledo, OH, USA and
    Drug Metab Rev 45:431-40. 2013
    ..These findings provide a foundation for using zebrafish as a model for investigating further the physiological, pharmacological, and toxicological involvement of the SULTs...
  7. doi Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: role of the human SULT1A3
    Shin Yasuda
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43614, USA
    Toxicol Appl Pharmacol 251:104-9. 2011
    ..Collectively, these results suggest that sulfation by SULT1A3 in lung endothelial and epithelial cells may play a role in the inactivation and/or disposal of excess chlorotyrosine and nitrotyrosine generated during inflammation...
  8. doi Hydroxylated serotonin and dopamine as substrates and inhibitors for human cytosolic SULT1A3
    Shin Yasuda
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, Ohio, USA
    J Neurochem 103:2679-89. 2007
    ..By serving as substrates for SULT1A3, these hydroxylated monoamines may interfere with the homeostasis of endogenous serotonin and dopamine...
  9. pmc Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs
    Katsuhisa Kurogi
    Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, 3000 Arlington Avenue, Toledo, OH 43614, USA
    Biochem Pharmacol 84:1186-95. 2012
    ..Collectively, the results from the present study implied the concerted actions of the COMT and SULT1A3 in the metabolism of catecholic drugs...
  10. ncbi On the sulfation and methylation of catecholestrogens in human mammary epithelial cells and breast cancer cells
    Ying Hui
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA
    Biol Pharm Bull 31:769-73. 2008
    ..Enzymatic assays revealed that, five (SULT1A1, SULT1A2, SULT1A3, SULT1C4, and SULT1E1) of eleven known human SULTs tested could use CEs and methoxyestrogens (MEs) as substrates, with SULT1E1 displaying the strongest sulfating activity...
  11. pmc A comparative study of the sulfation of bile acids and a bile alcohol by the Zebra danio (Danio rerio) and human cytosolic sulfotransferases (SULTs)
    Katsuhisa Kurogi
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43614, USA
    J Steroid Biochem Mol Biol 127:307-14. 2011
    ..Collectively, the results imply that the Zebra danio and human SULTs have evolved to serve for the sulfation of, respectively, bile alcohols and bile acids, matching the cholanoid profile in these two vertebrate species...
  12. pmc Identification, characterization, and ontogenic study of a catechol O-methyltransferase from zebrafish
    Adnan Alazizi
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43614, USA
    Aquat Toxicol 102:18-23. 2011
    ..These results provide a foundation for investigating the involvement of COMT-mediated methylation in protection against the adverse effects of catechol drugs and other xenobiotic catechols during the developmental process...
  13. ncbi Ethanol sulfation by the human cytosolic sulfotransferases: a systematic analysis
    Katsuhisa Kurogi
    Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, Toledo, OH 43614, USA
    Biol Pharm Bull 35:2180-5. 2012
    ..Cytosol or S9 fractions of human lung, liver, and small intestine were examined to verify the presence of ethanol-sulfating activity in vivo. Of the three human organs, the small intestine displayed the highest activity...
  14. doi Characterization and ontogenic study of novel steroid-sulfating SULT3 sulfotransferases from zebrafish
    Tomoko Yasuda
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA
    Mol Cell Endocrinol 294:29-36. 2008
    ..Collectively, these results imply that these two steroid-sulfating SULT3 STs may play differential roles in the metabolism and regulation of steroids during zebrafish development and in adulthood...
  15. ncbi Zebrafish as a model for the study of the phase II cytosolic sulfotransferases
    Tzu An Liu
    Department of Pharmacology, The University of Toledo, Toledo, OH 43606, USA
    Curr Drug Metab 11:538-46. 2010
    ..The information obtained, as summarized in this review, provides a foundation for further investigation into the physiological and pharmacological involvement of the SULTs using the zebrafish as a model...
  16. ncbi Inhibitory effects of nitrative stress on the sulfation of 17β-estradiol and 4-methoxyestradiol by human MCF 10A mammary epithelial cells
    Ying Hui
    College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA
    Biol Pharm Bull 33:1633-7. 2010
    ..Moreover, cell lysates prepared from MCF-10A cells treated with SIN-1 or DETA NONOate also showed much lower 4-methoxyestradiol-sulfating activities, compared with those determined with cell lysate prepared from control MCF-10A cells...
  17. ncbi Sulfation of buprenorphine, pentazocine, and naloxone by human cytosolic sulfotransferases
    Katsuhisa Kurogi
    Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, 3000 Arlington Avenue, Toledo, OH 43614, USA
    Drug Metab Lett 6:109-15. 2012
    ..Collectively, these results imply that sulfation may play a role in the metabolism of buprenorphine, pentazocine, and naloxone in vivo...
  18. pmc A target-specific approach for the identification of tyrosine-sulfated hemostatic proteins
    Tzu An Liu
    Department of Pharmacology, University of Toledo, Toledo, OH 43606, USA
    Anal Biochem 390:88-90. 2009
    ....
  19. pmc Developmental toxicity of dextromethorphan in zebrafish embryos/larvae
    Zheng Xu
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43606 USA
    J Appl Toxicol 31:157-63. 2011
    ....
  20. doi Concerted action of the cytosolic sulfotransferase, SULT1A3, and catechol-O-methyltransferase in the metabolism of dopamine in SK-N-MC human neuroblastoma cells
    Shin Yasuda
    Department of Pharmacology, College of Pharmacy, The University of Toledo, Toledo, OH 43606, USA
    Neurosci Res 64:273-9. 2009
    ..Collectively, these results imply a concerted action of sulfation and methylation in the irreversible inactivation and disposal of excess dopamine in SK-N-MC cells...
  21. ncbi Regulation of urokinase receptor expression by phosphoglycerate kinase is independent of its catalytic activity
    Sreerama Shetty
    Department of Medicine, University of Texas Health Center, Tyler, TX 75708, USA
    Am J Physiol Lung Cell Mol Physiol 289:L591-8. 2005
    ..These results demonstrate that uPAR mRNA binding activity as well as PGK-mediated regulation of uPAR mRNA are independent of PGK enzymatic activity...
  22. doi The effects of mixtures of dichloroacetate and trichloroacetate on induction of oxidative stress in livers of mice after subchronic exposure
    Ezdihar Hassoun
    a College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, Ohio, USA
    J Toxicol Environ Health A 77:313-23. 2014
    ..Hence, there may be rise in exposure risk to these compounds as these agents coexist in drinking water. ..
  23. pmc Identification of a novel flavonoid glycoside sulfotransferase in Arabidopsis thaliana
    Takuyu Hashiguchi
    Department of Biochemistry and Applied Biosciences Interdisciplinary Graduate School of Agriculture and Engineering, University of Miyazaki, Miyazaki 889 2192, Japan and Department of Pharmacology, College of Pharmacy and Pharmaceutical Sciences, The University of Toledo, OH 43614, USA
    J Biochem 155:91-7. 2014
    ..In addition, by using direct infusion mass spectrometry, it was found that the sulfated product had one sulfonate group within the molecule. These results indicated that AtSULT202B7 functions as a flavonoid glycoside 7-sulfotransferase. ..
  24. ncbi Posttranscriptional regulation of urokinase receptor expression by heterogeneous nuclear ribonuclear protein C
    Thirunavukkarasu Velusamy
    Texas Lung Injury Institute, Department of Specialty Care Services, The University of Texas Health Center at Tyler, 11937 U S Highway 271, Tyler, Texas 75708, USA
    Biochemistry 47:6508-17. 2008
    ..Increased hnRNPC interaction with the uPAR mRNA 3'-UTR through phosphorylation of Y57 represents a novel mechanism by which uPA regulates posttranscriptional uPAR mRNA turnover and cell surface uPAR expression...
  25. ncbi cDNA cloning, expression, and functional characterization of a zebrafish SULT1 cytosolic sulfotransferase
    Takuya Sugahara
    Biomedical Research Center, The University of Texas Health Center, Tyler 75708, USA
    Arch Biochem Biophys 414:67-73. 2003
    ..Among 10 divalent metal cations tested, Hg(2+), Co(2+), Zn(2+), Cd(2+), Cu(2+), and Pb(2+) exhibited dramatic inhibitory effects on the activity of the zebrafish sulfotransferase...
  26. pmc Sulphonation of dehydroepiandrosterone and neurosteroids: molecular cloning, expression, and functional characterization of a novel zebrafish SULT2 cytosolic sulphotransferase
    Takuya Sugahara
    Biomedical Research Center, The University of Texas Health Center, Tyler, TX 75708, USA
    Biochem J 375:785-91. 2003
    ..These results constitute the first study on the molecular cloning, expression, and characterization of a zebrafish cytosolic SULT2 ST...
  27. pmc Generation and release of nitrotyrosine O-sulfate by HepG2 human hepatoma cells upon SIN-1 stimulation: identification of SULT1A3 as the enzyme responsible
    Shin Yasuda
    Biomedical Research Center and The Texas Lung Injury Institute, The University of Texas Health Center, 11937 U S Highway 271, Tyler, TX 75708, USA
    Biochem J 401:497-503. 2007
    ..The proportion of sulfated [3H]nitrotyrosine increased dramatically in the medium over time, implying that sulfation may play a significant role in the metabolism of free nitrotyrosine...
  28. ncbi Identification of a novel estrogen-sulfating cytosolic SULT from zebrafish: molecular cloning, expression, characterization, and ontogeny study
    Shin Yasuda
    Biomedical Research Center, The University of Texas Health Center, Tyler, TX 75708, USA
    Biochem Biophys Res Commun 330:219-25. 2005
    ....
  29. ncbi Identification of novel hydroxysteroid-sulfating cytosolic SULTs, SULT2 ST2 and SULT2 ST3, from zebrafish: cloning, expression, characterization, and developmental expression
    Shin Yasuda
    Biomedical Research Center, The University of Texas Health Center, Tyler, TX 75708, USA
    Arch Biochem Biophys 455:1-9. 2006
    ....
  30. ncbi Sulfation of hydroxychlorobiphenyls. Molecular cloning, expression, and functional characterization of zebrafish SULT1 sulfotransferases
    Takuya Sugahara
    Biomedical Research Center, The University of Texas Health Center, Tyler, Texas 75708, USA
    Eur J Biochem 270:2404-11. 2003
    ..Among 10 different divalent metal cations tested, Co2+, Zn2+, Cd2+, and Pb2+ exhibited considerable inhibitory effects, while Hg2+ and Cu2+ rendered both enzymes virtually inactive...
  31. doi Molecular cloning, expression, and characterization of mouse amine N-sulfotransferases
    Saki Takahashi
    Department of Biochemistry and Applied Biosciences, University of Miyazaki, 1 1, Gakuenkibanadai nishi, Miyazaki, Miyazaki 889 2192, Japan
    Biochem Biophys Res Commun 375:531-5. 2008
    ..Collectively, these results imply that these two amine-sulfonating SULT3s may play essential roles in the metabolism and detoxification of aromatic amine compounds in the body...
  32. ncbi Manganese stimulation and stereospecificity of the Dopa (3,4-dihydroxyphenylalanine)/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase. Kinetic studies of the mechanism using wild-type and mutant enzymes
    T Govind Pai
    Biomedical Research Center, The University of Texas Health Center, Tyler 75708, USA
    J Biol Chem 277:43813-20. 2002
    ....
  33. ncbi Differential xenoestrogen-sulfating activities of the human cytosolic sulfotransferases: molecular cloning, expression, and purification of human SULT2B1a and SULT2B1b sulfotransferases
    T Govind Pai
    Department of Biochemistry, Biomedical Research Center, The University of Texas Health Center at Tyler, 11937 US Hwy 271, Tyler, TX 75708, USA
    Biochim Biophys Acta 1573:165-70. 2002
    ..Kinetic studies on the sulfation of xenoestrogens by P-form (SULT1A1) PST were performed. The results are interpreted in the context of the endocrine-disrupting nature of these xenoestrogens...
  34. ncbi Structure-function relationships in the stereospecific and manganese-dependent 3,4-dihydroxyphenylalanine/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase, SULT1A3
    T Govind Pai
    Biomedical Research Center, The University of Texas Health Center, Tyler, Texas 75708, USA
    J Biol Chem 278:1525-32. 2003
    ..These studies could be relevant in understanding the stereoselective action of SULT1A3 on chiral drugs...
  35. ncbi Differential roles of human monoamine (M)-form and simple phenol (P)-form phenol sulfotransferases in drug metabolism
    Takuya Sugahara
    Biomedical Research Center, The University of Texas Health Center, 11937 US Hwy 271, Tyler, TX 75708, USA
    J Biochem 133:259-62. 2003
    ....
  36. ncbi Sulfonation of environmental estrogens by zebrafish cytosolic sulfotransferases
    Kei Ohkimoto
    Biomedical Research Center, The University of Texas Health Center, Tyler, TX 75708, USA
    Biochem Biophys Res Commun 309:7-11. 2003
    ..Kinetic studies revealed that the mechanism underlying the inhibition by bisphenol A or 4-n-nonylphenol to be of the competitive type...
  37. ncbi Characterization of a zebrafish estrogen-sulfating cytosolic sulfotransferase: inhibitory effects and mechanism of action of phytoestrogens
    Kei Ohkimoto
    Biomedical Research Center, The University of Texas Health Center, 11937 US Highway 271, Tyler, TX 75708, USA
    Chem Biol Interact 147:1-7. 2004
    ..The IC(50) determined for quercetin, genistein, and daidzein were 0.7, 2.5, and 8 microM, respectively. Kinetic analyses revealed that the mechanism underlying the inhibition by these isoflavones to be of the competitive type...
  38. ncbi Zebrafish tyrosylprotein sulfotransferase: molecular cloning, expression, and functional characterization
    Emi Mishiro
    Biomedical Research Center, University of Texas Health Center, Tyler, 75708, USA
    Biochem Cell Biol 82:295-303. 2004
    ..These results constitute a first study on the cloning, expression, and characterization of a zebrafish cytosolic TPST...
  39. ncbi Oral contraceptives as substrates and inhibitors for human cytosolic SULTs
    Shin Yasuda
    Biomedical Research Center, The University of Texas Health Center, 11937 U S Highway 271, Tyler, TX 75708, USA
    J Biochem 137:401-6. 2005
    ..Moreover, in view of their inhibitory effects on the sulfation of 17beta-estradiol, these compounds may potentially act to disrupt the homeostasis of endogenous estrogens...
  40. ncbi Identification of a novel zebrafish SULT1 cytosolic sulfotransferase: cloning, expression, characterization, and developmental expression study
    Ming Yih Liu
    Biomedical Research Center, The University of Texas Health Center, Tyler, TX 75708, USA
    Arch Biochem Biophys 437:10-9. 2005
    ....
  41. ncbi Identification of a novel thyroid hormone-sulfating cytosolic sulfotransferase, SULT1 ST5, from zebrafish
    Shin Yasuda
    Biomedical Research Center, The University of Texas Health Center, Tyler 75708, USA
    FEBS J 272:3828-37. 2005
    ....
  42. ncbi Crystal structure of human sulfotransferase SULT1A3 in complex with dopamine and 3'-phosphoadenosine 5'-phosphate
    Jing Hua Lu
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Bejing 100101, PR China
    Biochem Biophys Res Commun 335:417-23. 2005
    ..On the other hand, residue Asp86 appeared to be critical to the Mn2+-stimulation of the Dopa/tyrosine-sulfating activity of SULT1A3, in addition to a supporting role in the stereoselectivity and sulfating activity...
  43. ncbi Cigarette smoke toxicants as substrates and inhibitors for human cytosolic SULTs
    Shin Yasuda
    Biomedical Research Center, The University of Texas Health Center, 11937 US Highway 271, Tyler, TX 75708, USA
    Toxicol Appl Pharmacol 221:13-20. 2007
    ..By serving as substrates for SULTs, cigarette smoke toxicants may interfere with the metabolism of 17beta-estradiol and other endogenous compounds...
  44. ncbi Immunohistochemical analysis of a novel dehydroepiandrosterone sulfotransferase-like protein in Drosophila neural circuits
    Tzu An Liu
    Department of Biological Science and Technology, Institute of Biochemical Engineering, National Chiao Tung University, 75 Po Ai Street, Hsinchu 30050, Taiwan
    Biochem Biophys Res Commun 367:14-20. 2008
    ..Clarification of a possible link between ST and a neurotransmitter-mediated effect may eventually aid in designing approaches for alleviating neuronal disorders in humans...
  45. pmc Urokinase expression by tumor suppressor protein p53: a novel role in mRNA turnover
    Praveenkumar Shetty
    The Texas Lung Injury Institute, Department of Specialty Care Services, The University of Texas Health Center at Tyler, Tyler, Texas 75708, USA
    Am J Respir Cell Mol Biol 39:364-72. 2008
    ..These observations confirm a new role for p53 as a uPA mRNA binding protein that down-regulates uPA mRNA stability and decreases cellular uPA expression...
  46. ncbi Differential enzymatic characteristics and tissue-specific expression of human TPST-1 and TPST-2
    Emi Mishiro
    Department of Biochemistry and Applied Biosciences, Faculty of Agriculture, University of Miyazaki, Miyazaki 889 2192
    J Biochem 140:731-7. 2006
    ..These latter findings may imply distinct physiological functions of TPST-1 and TPST-2...
  47. ncbi Regulatory effects of divalent metal cations on human cytosolic sulfotransferases
    Faye Xu
    Biomedical Research Center, The University of Texas Health Center, Tyler, TX 75708, USA
    J Biochem 132:457-62. 2002
    ..Using the monoamine (M)-form phenol ST (PST) as a model, it was demonstrated that the K(m) for dopamine changed only slightly with increasing concentrations of Cd2+, whereas the V(max) was dramatically decreased...