Jun Liu

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi Markers improve clustering of CGH data
    Jun Liu
    Computer and Information Science and Engineering, University of Florida, Gainesville, FL 32611, USA
    Bioinformatics 23:450-7. 2007
  2. pmc Classification and feature selection algorithms for multi-class CGH data
    Jun Liu
    Computer and Information Science and Engineering, University of Florida, Gainesville, FL 32611, USA
    Bioinformatics 24:i86-95. 2008
  3. ncbi Distance-based clustering of CGH data
    Jun Liu
    Computer and Information Science and Engineering, University of Florida Gainesville, FL 32611, USA
    Bioinformatics 22:1971-8. 2006
  4. doi Inferring progression models for CGH data
    Jun Liu
    Computer and Information Science and Engineering, University of Florida, Gainesville, FL, USA
    Bioinformatics 25:2208-15. 2009
  5. ncbi Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin
    Gary A Visner
    Department of Pediatrics, College of Medicine, University of Florida, Gainesville 32610, USA
    Circulation 107:911-6. 2003
  6. ncbi A model-based approach in the estimation of the maximum tolerated dose in phase I cancer clinical trials
    Weili He
    Clinical Biostatistics, Merck Research Labs, Merck and Co, Inc, Rahway, NJ 07065, USA
    Stat Med 25:2027-42. 2006
  7. ncbi The HMX homeodomain protein MLS-2 regulates cleavage orientation, cell proliferation and cell fate specification in the C. elegans postembryonic mesoderm
    Yuan Jiang
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
    Development 132:4119-30. 2005
  8. ncbi [Screen of differentially expressed genes between gastrula embryos and tail bud embryos in gynogenetic gibel carp (Carassius auratus gibelio)]
    Jun Liu
    State Key Laboratory of Freshwater Ecology and Biotechnology, Wuhan Center for Developmental Biology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China
    Yi Chuan Xue Bao 32:253-63. 2005
  9. ncbi Online clustering algorithms for radar emitter classification
    Jun Liu
    TechnoCom Corporation, 16133 Ventura Blvd, Suite 640, Encino, CA 91436, USA
    IEEE Trans Pattern Anal Mach Intell 27:1185-96. 2005
  10. pmc Fusion transcripts and transcribed retrotransposed loci discovered through comprehensive transcriptome analysis using Paired-End diTags (PETs)
    Yijun Ruan
    Genome Technology and Biology Group, Genome Institute of Singapore, Singapore 138672, Singapore
    Genome Res 17:828-38. 2007

Detail Information

Publications63

  1. ncbi Markers improve clustering of CGH data
    Jun Liu
    Computer and Information Science and Engineering, University of Florida, Gainesville, FL 32611, USA
    Bioinformatics 23:450-7. 2007
    ..A key requirement for clustering is to avoid using the noisy aberrations in the CGH samples...
  2. pmc Classification and feature selection algorithms for multi-class CGH data
    Jun Liu
    Computer and Information Science and Engineering, University of Florida, Gainesville, FL 32611, USA
    Bioinformatics 24:i86-95. 2008
    ..Our results on datasets generated from the Progenetix database, suggests that our methods are considerably superior to existing methods...
  3. ncbi Distance-based clustering of CGH data
    Jun Liu
    Computer and Information Science and Engineering, University of Florida Gainesville, FL 32611, USA
    Bioinformatics 22:1971-8. 2006
    ..Our expectation is that patients with the same cancer types will generally belong to the same cluster as their underlying CGH profiles will be similar...
  4. doi Inferring progression models for CGH data
    Jun Liu
    Computer and Information Science and Engineering, University of Florida, Gainesville, FL, USA
    Bioinformatics 25:2208-15. 2009
    ..Understanding the relationship between CNAs and different cancer types is a fundamental problem in cancer studies...
  5. ncbi Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin
    Gary A Visner
    Department of Pediatrics, College of Medicine, University of Florida, Gainesville 32610, USA
    Circulation 107:911-6. 2003
    ..Heme oxygenase-1 (HO-1) has also been shown to have graft protective effects and to inhibit vascular remodeling. In this study, we evaluated whether there is an interaction between rapamycin and HO-1...
  6. ncbi A model-based approach in the estimation of the maximum tolerated dose in phase I cancer clinical trials
    Weili He
    Clinical Biostatistics, Merck Research Labs, Merck and Co, Inc, Rahway, NJ 07065, USA
    Stat Med 25:2027-42. 2006
    ..Furthermore, our model-based approach can be easily extended to any traditional A+B design...
  7. ncbi The HMX homeodomain protein MLS-2 regulates cleavage orientation, cell proliferation and cell fate specification in the C. elegans postembryonic mesoderm
    Yuan Jiang
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA
    Development 132:4119-30. 2005
    ..Furthermore, the C. elegans Myod homolog HLH-1 acts downstream of mls-2 to specify M-derived coelomocyte cell fates. Thus MLS-2 functions in a cell type-specific manner to regulate both cell proliferation and cell fate specification...
  8. ncbi [Screen of differentially expressed genes between gastrula embryos and tail bud embryos in gynogenetic gibel carp (Carassius auratus gibelio)]
    Jun Liu
    State Key Laboratory of Freshwater Ecology and Biotechnology, Wuhan Center for Developmental Biology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China
    Yi Chuan Xue Bao 32:253-63. 2005
    ..The screen of these differentially expressed genes will help us to understand the molecular mechanism in gibel carp embryogenesis...
  9. ncbi Online clustering algorithms for radar emitter classification
    Jun Liu
    TechnoCom Corporation, 16133 Ventura Blvd, Suite 640, Encino, CA 91436, USA
    IEEE Trans Pattern Anal Mach Intell 27:1185-96. 2005
    ..Simulation results show the superior performance of the model-based algorithm over competitive learning in terms of better classification accuracy, flexibility, and stability...
  10. pmc Fusion transcripts and transcribed retrotransposed loci discovered through comprehensive transcriptome analysis using Paired-End diTags (PETs)
    Yijun Ruan
    Genome Technology and Biology Group, Genome Institute of Singapore, Singapore 138672, Singapore
    Genome Res 17:828-38. 2007
    ..The PET mapping strategy presented here promises to be a useful tool in annotating the human genome, especially aberrations in human cancer genomes...
  11. ncbi Disruption of MEF2 activity in cardiomyoblasts inhibits cardiomyogenesis
    Christina Karamboulas
    Department of Biochemistry, Medical Sciences Building, University of Western Ontario, London, Ontario, N6A 5C1, Canada
    J Cell Sci 119:4315-21. 2006
    ..Our results show that MEF2C, or genes containing MEF2 DNA-binding sites, is required for the efficient differentiation of cardiomyoblasts into cardiomyocytes, suggesting conservation in the role of MEF2 from Drosophila to mammals...
  12. ncbi Compatibility of porcine and human interleukin 2: implications for xenotransplantation
    Baojun Zhang
    State Key Laboratory of Biomembrane and Membrane Biotechnology, Transplantation Biology Research Division, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    Xenotransplantation 13:423-32. 2006
    ..Therefore, it is essential to understand of the compatibility of IL2 between pigs and humans...
  13. ncbi 2-methoxyestradiol reduces cerebral vasospasm after 48 hours of experimental subarachnoid hemorrhage in rats
    Junhao Yan
    Department of Anatomy and Embryology, Peking University Health Science Center, Beijing, China 100083
    Exp Neurol 202:348-56. 2006
    ....
  14. ncbi Genetic variations in radiation and chemotherapy drug action pathways predict clinical outcomes in esophageal cancer
    Xifeng Wu
    Department of Epidemiology, Experimental Therapeutics, GI Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:3789-98. 2006
    ..Understanding how specific genetic variants modify drug action pathways may provide informative blueprints for individualized chemotherapy...
  15. ncbi Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase
    Jun Chen
    Center for Drug Discovery, College of Pharmacy, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China
    Bioorg Med Chem Lett 16:2915-9. 2006
    ..Within this series of compounds, 4 (IC50 = 3.3 microM) is the most potent GPa inhibitor. Preliminary structure-activity relationships of the oleanolic acid derivatives are discussed...
  16. ncbi Cloning, characterization and tissue-specific expression of a cDNA encoding a novel EMBRYONIC FLOWER 2 gene (OsEMF2) in Oryza sativa
    Kegui Li
    Institute of Genetics, State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, P R China
    DNA Seq 17:74-8. 2006
    ..The tissue-specific expression pattern of OsEMF2 reveals that it is abundant in shoot apical meristem and inflorescence meristem, while its expression level is much lower in leaf, root, immature seed and callus...
  17. ncbi [Application research on the flow-through hybridization and gene chip in human papillomavirus detection]
    Ping Ping Tao
    Department of Obstetrics and Gynecology, China Japan Friendship Hospital, Beijing 100029, China
    Zhonghua Fu Chan Ke Za Zhi 41:43-7. 2006
    ..To evaluate the clinical efficacy of flow-through hybridization and gene chip (HybriMax) on female low genital human papillomavirus (HPV) detection and to identify the most common HPV genotypes...
  18. pmc BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells
    Qiang Song Tong
    Department of Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    BMC Cancer 4:33. 2004
    ..In this study, we explored the therapeutic effects of gene transfer mediated elevations in BAK expression on human gastric cancer cells in vitro...
  19. ncbi The relation between D-galactose injection and mitochondrial DNA 4834 bp deletion mutation
    Wei Jia Kong
    Department of Otorhinolaryngology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Jiefang Avenue 1277, Wuhan 430022, China
    Exp Gerontol 41:628-34. 2006
    ..A higher sensitive result could be gained using tissue biopsy to examine mtDNA 4834 bp deletion...
  20. ncbi Oct-3/4 dose dependently regulates specification of embryonic stem cells toward a cardiac lineage and early heart development
    Dana Zeineddine
    CNRS FRE2593, CRBM, 34293 Montpellier, France
    Dev Cell 11:535-46. 2006
    ..Thus, quantitative Oct-3/4 expression is regulated by a morphogen, pointing to a pivotal and physiological function of the POU factor in mesodermal and cardiac commitments of ES cells and of the epiblast...
  21. ncbi Identification of the lipooligosaccharide biosynthetic gene cluster from Mycobacterium marinum
    Huiping Ren
    Department of Medical Genetics and Microbiology, University of Toronto, 1 King s College Circle, Toronto, Ontario M5S 1A8, Canada
    Mol Microbiol 63:1345-59. 2007
    ..This is an important step in assessing the differential distribution of LOSs among Mycobacterium species and understanding the role of LOSs in mycobacterial virulence...
  22. ncbi [Identification of the habitats of Radix Astragali using the correlative characteristic peaks selected by rough sets]
    Lei Nie
    Shandong University, Pharmacy School, Jinan 250010, China
    Zhong Yao Cai 29:1020-3. 2006
    ..Correlative characteristic peaks of HPLC selected by rough sets were employed to identify the habitats of Radix Astragali...
  23. doi New pentacyclic triterpenes from Gypsophila oldhamiana and their biological evaluation as glycogen phosphorylase inhibitors
    Jian Guang Luo
    Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, PR China
    Chem Biodivers 5:751-7. 2008
    ..These triterpenes were evaluated for their glycogen phosphorylase inhibitory activity and preliminary structure-activity trends are suggested...
  24. ncbi [PI-3K and p38MAPK pathways upregulate the epidermal growth factor induced cyclooxygenase-2 expression in PC-3 cells]
    Rui Peng Jia
    Department of Urology, the First Hospital of Nanjing Affiliated to Nanjing Medical University, Nanjing, Jiangsu 210006, China
    Zhonghua Nan Ke Xue 14:220-3. 2008
    ..To investigate the effect of PI-3K and p38MAPK signal pathways on the cyclooxygenase-2 (COX-2) expression induced by the epidermal growth factor (EGF) in PC-3 cells...
  25. doi Pattern representation in feature extraction and classifier design: matrix versus vector
    Zhe Wang
    Department of Computer Science and Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, PRChina
    IEEE Trans Neural Netw 19:758-69. 2008
    ....
  26. pmc Systematic analysis of pleiotropy in C. elegans early embryogenesis
    Lihua Zou
    Department of Statistics, Harvard University, Cambridge, Massachusetts, USA
    PLoS Comput Biol 4:e1000003. 2008
    ....
  27. pmc The use of multiple displacement amplification to amplify complex DNA libraries
    Melissa J Fullwood
    Genome Institute of Singapore, Agency for Science, Technology and Research A STAR, 60 Biopolis Street, Genome 02 01, Singapore
    Nucleic Acids Res 36:e32. 2008
    ....
  28. pmc Dorsoventral patterning of the C. elegans postembryonic mesoderm requires both LIN-12/Notch and TGFbeta signaling
    Marisa L Foehr
    Department of Molecular Biology and Genetics, Cornell University, 439 Biotechnology Building, Ithaca, NY 14853, USA
    Dev Biol 313:256-66. 2008
    ..Our work provides a model for how combined Notch and TGFbeta signaling regulates the developmental potential of two equipotent cells along the dorsoventral axis...
  29. ncbi Developmental expression of CagMdkb during gibel carp embryogenesis
    Jun Yin
    State Key Laboratory of Freshwater Ecology and Biotechnology, Wuhan Center for Developmental Biology, Institute of Hydrobiology, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Wuhan, China
    Int J Dev Biol 51:761-9. 2007
    ..All these findings indicate that CagMdkb plays an important role in neural development during gibel carp embryogenesis and there is functional conservation of Mdkb in fish head formation...
  30. ncbi Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme
    Ling Chen
    Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China
    Bioorg Med Chem 15:6763-74. 2007
    ....
  31. ncbi Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension
    Qiang Zhao
    Division of Cardiac Surgery, Zhongshan Hospital, Fudan University, Shanghai, PR China
    Ann Thorac Surg 84:544-52. 2007
    ..We evaluated the therapeutic effect of intravenously administered CGRP-expressing endothelial progenitor cells (EPCs) on left-to-right shunt-induced pulmonary hypertension in rats...
  32. ncbi Systematic evaluation of genetic variants in the inflammation pathway and risk of lung cancer
    Eric A Engels
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Cancer Res 67:6520-7. 2007
    ..IL1A and IL1B are critical signals in initiating inflammation. Our results suggest that a dysregulated inflammatory response to tobacco-induced lung damage promotes carcinogenesis...
  33. ncbi [Inhibitory effect of AG490 on invasion and metastasis of human pancreatic cancer cells in vitro]
    Chen Huang
    Department of General Surgery, Affiliated First People s Hospital, Shanghai Jiao Tong University, Shanghai 200080, China
    Zhonghua Zhong Liu Za Zhi 28:890-3. 2006
    ..To investigate the effect and mechanism of blockade of STAT3 signaling pathway by JAK specific inhibitor-AG490 on invasion and metastasis of human highly metastatic pancreatic cancer line SW1990 in vitro...
  34. ncbi Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth
    Jun Liu
    Department of Biochemistry, Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
    J Cell Sci 119:933-42. 2006
    ..These findings are the first to identify upregulated C6st1 gene expression correlating with the motility of Schwann cells that guide growing axons through both developmental and injured environments...
  35. ncbi Mapping heparanase expression in the spinal cord of adult rats
    Yi Zhang
    Department of Biochemistry, Faculty of Medicine, The University of Hong Kong, China
    J Comp Neurol 494:345-57. 2006
    ....
  36. pmc The activity profile of the NhaD-type Na+(Li+)/H+ antiporter from the soda Lake Haloalkaliphile Alkalimonas amylolytica is adaptive for the extreme environment
    Jun Liu
    Institute of Microbiology, Chinese Academy of Sciences, Beijing, People s Republic of China
    J Bacteriol 187:7589-95. 2005
    ..coli setting: a much higher activity than wild-type NhaD at Na(+) concentrations up to 200 mM but lower activity at 400 to 600 mM Na(+), with a pH optimum and minimal pH for activity lower than those of wild-type NhaD...
  37. ncbi PAP7, a PBR/PKA-RIalpha-associated protein: a new element in the relay of the hormonal induction of steroidogenesis
    Jun Liu
    Division of Hormone Research, Department of Cell Biology, Georgetown University Medical Center, 3900 Reservoir Road NW, Washington, DC 20057, USA
    J Steroid Biochem Mol Biol 85:275-83. 2003
    ..Taken together, these data suggest that PAP7 functions as an A-kinase anchoring protein (AKAP) critical in the cAMP-dependent steroid formation...
  38. ncbi The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport
    Jun Liu
    Departments of Internal Medicine and Physiology, Life Sciences Institute, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
    J Biol Chem 278:36754-62. 2003
    ..Thus, both c-Cbl and Cbl-b can initiate a phosphatidylinositol 3-kinase/protein kinase B-independent signaling pathway critical to insulin-stimulated GLUT4 translocation...
  39. ncbi Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study
    Samer Karamohamed
    Framingham Heart Study Genetics Laboratory, Department of Neurology, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Diabetes 52:1562-7. 2003
    ..002) and type 2 diabetes (P < 0.001, odds ratio 1.96, 95% CI 1.28-3.00). The evidence presented supports the possibility that IDE is a susceptibility gene for diabetes in populations of European descent...
  40. ncbi Predictive functional control (PFC) and its application in chlorinated polyethylene process
    Hong Liang Li
    National Key Laboratory of Industrial Control Technology, Institute of Advanced Process Control, Zhejiang University, Hangzhou 310027, China
    J Zhejiang Univ Sci 4:300-4. 2003
    ..For a chlorinated polyethylene (CPE) process, a design scheme of cascade predictive functional control system is described and the control performance is improved obviously...
  41. ncbi Molecular cloning, genomic organization, chromosomal mapping and subcellular localization of mouse PAP7: a PBR and PKA-RIalpha associated protein
    Jun Liu
    Division of Hormone Research, Department of Cell Biology, Georgetown University Medical Center, 3900 Reservoir Road, NW, Washington, DC 20057, USA
    Gene 308:1-10. 2003
    ..e. mitochondria, where phosphorylation of specific protein substrates mediates the hormone-induced steroid formation...
  42. pmc MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in Caenorhabditis elegans
    Jun Liu
    Department of Molecular Biology and Genetics, 439 Biotechnology Building, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 100:4598-603. 2003
    ..These findings show that LEM domain proteins are essential for cell division and that Ce-emerin and Ce-MAN1 share at least one and possibly multiple overlapping functions, which may be relevant to Emery-Dreifuss muscular dystrophy...
  43. ncbi Use of a panel of congenic strains to evaluate differentially expressed genes as candidate genes for blood pressure quantitative trait loci
    Soon J Lee
    Department of Physiology and Molecular Medicine, Medical College of Ohio, Toledo, OH 43614, USA
    Hypertens Res 26:75-87. 2003
    ..This data suggests that Hao2 should be examined as a candidate gene for the rat chromosome 2 (RNO2) BP QTL...
  44. ncbi Transient mechanoactivation of neutral sphingomyelinase in caveolae to generate ceramide
    Malgorzata Czarny
    Sidney Kimmel Cancer Center, Division of Vascular Biology and Angiogenesis, San Diego, California 92121, USA
    J Biol Chem 278:4424-30. 2003
    ..We postulate a novel physiological function for neutral sphingomyelinase as a new mechanosensor initiating the ERK cascade and possibly other mechanotransduction pathways...
  45. ncbi Screen for stage-specific expression genes between tail bud stage and heartbeat beginning stage in embryogenesis of gynogenetic silver crucian carp
    Yao Hua Shi
    State Key Laboratory of Freshwater Ecology and Biotechnology, Wuhan Center for Developmental Biology, Institute of Hydrobiology, Chinese Academy of Sciences
    Cell Res 12:133-42. 2002
    ..This study is the first step for making a large attempt to study temporal and spatial control of gene expression in the gynogenetic fish embryogenesis...
  46. ncbi A linear plasmid temperature-sensitive for replication in Streptomyces hygroscopicus 10-22
    Xiuhua Pang
    Bio X Life Science Research Center, Shanghai Jiaotong University, 200030, Shanghai, PR China
    FEMS Microbiol Lett 208:25-8. 2002
    ..The distinct identity of pHZ6 from previously identified pHZ1-pHZ5 was demonstrated by the profile of relevant plasmids in six well-defined strains originated from S. hygroscopicus 10-22...
  47. pmc Lamin-dependent localization of UNC-84, a protein required for nuclear migration in Caenorhabditis elegans
    Kenneth K Lee
    Department of Cell Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Mol Biol Cell 13:892-901. 2002
    ..UNC-84 is not required for centrosome attachment to the nucleus because centrosomes are localized normally in unc-84 hyp7 cells despite a nuclear migration defect. Models for UNC-84 localization are discussed...
  48. ncbi The expression, lamin-dependent localization and RNAi depletion phenotype for emerin in C. elegans
    Yosef Gruenbaum
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    J Cell Sci 115:923-9. 2002
    ..elegans under laboratory growth conditions, and found no detectable phenotype throughout development. We propose that C. elegans is an appropriate system in which to study the molecular mechanisms of emerin function in vivo...
  49. pmc A rifampin-hypersensitive mutant reveals differences between strains of Mycobacterium smegmatis and presence of a novel transposon, IS1623
    David C Alexander
    Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada
    Antimicrob Agents Chemother 47:3208-13. 2003
    ..smegmatis strain mc(2)155 and previously described strain DSM 43756. The arr region of strain mc(2)155 contains a second, partial copy of the arr gene plus a novel insertion sequence, IS1623...
  50. ncbi pH-induced conformational changes of AcrA, the membrane fusion protein of Escherichia coli multidrug efflux system
    Hermia Ip
    Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada
    J Biol Chem 278:50474-82. 2003
    ..These results suggest that the mechanism of action of AcrA in drug efflux is similar to the viral membrane fusion proteins, and that AcrA actively mediates the efflux of substrates...
  51. ncbi Caveolin-1 expression enhances endothelial capillary tubule formation
    Jun Liu
    Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Biol Chem 277:10661-8. 2002
    ....
  52. ncbi Expression of a novel apoptosis inhibitor-survivin in colorectal carcinoma
    Hai Yan Tan
    Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China
    World J Gastroenterol 11:4689-92. 2005
    ..To investigate the role of survivin expression in the pathogenesis of colorectal carcinoma...
  53. ncbi [Angiotensin-(1-7) modulates fibrinolytic imbalance induced by oxidized low-density lipoprotein in cultured human umbilical vein endothelial cells]
    Li Jun Wang
    Department of Cardiology, First Affiliated Hospital of Sun Yat sen University, Guangzhou 510080, China
    Di Yi Jun Yi Da Xue Xue Bao 25:633-7. 2005
    ..To study the effect of angiotensin-(1-7)[Ang-(1-7)]on fibrinolytic imbalance induced by oxidized low- density lipoprotein (ox-LDL) in cultured human umbilical vein endothelial cells (HUVECs)...
  54. ncbi Actin gene in prawn, Macrobrachium rosenbergii: characteristics and differential tissue expression during embryonic development
    Xiao Jing Zhu
    College of Life Sciences, Zhejiang University, 232 Wensan Road, Hangzhou, PR China
    Comp Biochem Physiol B Biochem Mol Biol 140:599-605. 2005
    ..Expression of the Mar-actin gene varied during embryonic development and reached the maximal level at the zoea stage. This is the first report describing the complete sequence and expression pattern of the actin gene in prawns...
  55. pmc Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis
    Jun Liu
    Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
    Proc Natl Acad Sci U S A 102:1927-32. 2005
    ..These data suggest that LRRFIP2 plays an important role in transducing Wnt signals...
  56. pmc Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
    Otilia V Vieira
    Cell Biology Program, Hospital for Sick Children, and Department of Biochemistry, University of Toronto, Ontario M5G 1X8, Canada
    Mol Cell Biol 24:4593-604. 2004
    ..These findings suggest that the inability to recruit Hrs contributes to the arrest of phagosomal maturation induced by pathogenic mycobacteria...
  57. pmc Impact of methoxymycolic acid production by Mycobacterium bovis BCG vaccines
    Adam Belley
    Centre for the Study of Host Resistance, McGill University, Montreal H3G 1A4, Canada
    Infect Immun 72:2803-9. 2004
    ..Our results demonstrate that the loss of methoxymycolic acid production did not apparently affect the virulence of BCG strains...
  58. ncbi Aberration of X chromosome in liver neoplasm detected by fluorescence in situ hybridization
    Jun Liu
    Department of General Surgery, Qilu Hospital, Shandong University, Jinan 250012, China
    Hepatobiliary Pancreat Dis Int 3:110-4. 2004
    ..Identification of specific X chromosome alterations during the course of neoplastic development would be essential to defining the genetic basis of HCC. Therefore, we studied the regularity of aberration of X chromosome in liver cancer...
  59. ncbi Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain
    K Farid Ahmad
    Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada
    Mol Cell 12:1551-64. 2003
    ..Two SMRT fragments bind symmetrically to the BCL6 BTB homodimer and, in combination with biochemical and in vivo data, the structure provides insight into the basis of transcriptional repression by this critical B cell lymphoma protein...
  60. ncbi Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor
    Junjie Hu
    Skirball Institute of Biomolecular Medicine and Department of Pharmacology, New York University School of Medicine, New York, NY 10016, USA
    Mol Cell 12:1379-89. 2003
    ..This structure provides a molecular visualization of one of the initial downstream recruitment events following insulin activation of its dimeric receptor...
  61. ncbi The Caenorhabditis elegans schnurri homolog sma-9 mediates stage- and cell type-specific responses to DBL-1 BMP-related signaling
    Jun Liang
    Department of Biology, Queens College, The City University of New York, Flushing, NY 11367, USA
    Development 130:6453-64. 2003
    ..We propose that SMA-9 isoforms function as transcriptional cofactors that confer specific responses to DBL-1 pathway activation...
  62. ncbi Isolation of resistance related-genes to Phytophthora infestans with suppression subtractive hybridization in the R-gene-free potato
    Zhen Dong Tian
    College of Horticulture and Forestry, Huazhong Agricultural University, Wuhan 430070, China
    Yi Chuan Xue Bao 30:597-605. 2003
    ....
  63. ncbi 'Streptomyces nanchangensis', a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters
    Yuhui Sun
    Bio X Life Science Research Center, Shanghai Jiaotong University, Shanghai 200030, China
    Microbiology 148:361-71. 2002
    ....