Research Topics
| JOHN H LIUSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Exogenous vasopressin influences intraocular pressure via the V(1) receptorsE L Gondim
Glaucoma Center, Department of Ophthalmology, University of California-San Diego, La Jolla, CA 92093-0946, USA
Curr Eye Res 22:295-303. 2001..Reductions of IOP and pupil size following intravenous injections of vasopressin are at least partially due to stimulations of the V(1) receptors inside the eye...- Elevation of human intraocular pressure at night under moderate illuminationJ H Liu
Department of Ophthalmology, University of California, San Diego, La Jolla 92093 0946, USA
Invest Ophthalmol Vis Sci 40:2439-42. 1999..An endogenous elevation of intraocular pressure (IOP) occurs at night in healthy young adults. The authors studied whether or not this IOP elevation can be detected under moderate illumination... 
Diurnal and nocturnal effects of brimonidine monotherapy on intraocular pressureJohn H K Liu
Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, California, USA
Ophthalmology 117:2075-9. 2010..To investigate the effect of brimonidine monotherapy on intraocular pressure (IOP) during the nocturnal/sleep period...- Comparing diurnal and nocturnal effects of brinzolamide and timolol on intraocular pressure in patients receiving latanoprost monotherapyJohn H K Liu
The Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093 0946, USA
Ophthalmology 116:449-54. 2009..To compare the diurnal and nocturnal effects of brinzolamide and timolol on intraocular pressure (IOP) in patients already receiving monotherapy with latanoprost... - Sympathetic activities influence blood-flow velocity and resistance in the rabbit ophthalmic arteryJohn H K Liu
Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, La Jolla, CA 92093 0946, USA
J Ocul Pharmacol Ther 23:110-5. 2007..The aim of this study was to investigate sympathetic influences on blood-flow velocity and resistance in the rabbit ophthalmic artery during the transition period from the light to the dark phase... - Resistance to blood flow in the rabbit ophthalmic artery after topical treatment with timololJohn H K Liu
Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, La Jolla, CA 92039 0946, USA
J Ocul Pharmacol Ther 23:103-9. 2007..The aim of this study was to investigate the resistance to blood flow in the ophthalmic artery of rabbits receiving topical treatment with timolol... - Asymmetry of 24-hour intraocular pressure reduction by topical ocular hypotensive medications in fellow eyesJohn H K Liu
Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, California, USA
Ophthalmology 118:1995-2000. 2011..This assumption was evaluated for 24-hour IOP reduction in patients who underwent monotherapy or adjunctive therapy... - Variation of 24-hour intraocular pressure in healthy individuals: right eye versus left eyeJohn H K Liu
Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093 0946, USA
Ophthalmology 112:1670-5. 2005..We evaluated whether or not 24-hour variations of IOP in the two eyes are similar in healthy individuals... - Nocturnal elevation of intraocular pressure is detectable in the sitting positionJohn H K Liu
Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093, USA
Invest Ophthalmol Vis Sci 44:4439-42. 2003..This study was undertaken to investigate whether a similar elevation of IOP can be detected when experimental subjects are in the sitting position... - Laboratory assessment of diurnal and nocturnal ocular perfusion pressures in humansJohn H K Liu
Department of Opthalmology, University of California, San Diego, La Jolla, California 92093 0946, USA
J Ocul Pharmacol Ther 19:291-7. 2003..The diurnal-to-nocturnal increase of ocular perfusion pressure was larger in the older group than in the younger group... - Twenty-four-hour pattern of intraocular pressure in the aging populationJ H Liu
Department of Ophthalmology, University of California, San Diego, La Jolla 92093 0946, USA
Invest Ophthalmol Vis Sci 40:2912-7. 1999..To characterize the 24-hour pattern of intraocular pressure (IOP) in a sample of the aging human population... - Circadian variations of prostaglandins in the rabbit aqueous humorJ H Liu
Department of Ophthalmology, University of California, San Diego, La Jolla 92093 0946, USA
J Ocul Pharmacol Ther 16:49-54. 2000..However, vitreous humor concentrations of prostaglandin D2 and F2alpha were significantly higher than their concentrations in the aqueous humor... - Circadian variations of transforming growth factor-beta2 and basic fibroblast growth factor in the rabbit aqueous humorJohn H K Liu
Department of Ophthalmology, University of California, San Diego, La Jolla, CA 92093 0946, USA
Curr Eye Res 24:75-80. 2002..To compare levels of transforming growth factor-beta2 (TGF-beta2) and basic fibroblast growth factor (bFGF) in the ocular fluids of rabbits at various times of the day... - Twenty-four-hour pattern of intraocular pressure in young adults with moderate to severe myopiaJohn H K Liu
Department of Ophthalmology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0946, USA
Invest Ophthalmol Vis Sci 43:2351-5. 2002..To characterize the 24-hour change of intraocular pressure (IOP) in young adults with moderate to severe myopia... - Sympathetic nervous system plays a role in postnatal eyeball enlargement in the rabbitJ H Liu
Department of Ophthalmology, University of California, San Diego, La Jolla 92093 0946, USA
Invest Ophthalmol Vis Sci 41:2684-8. 2000..To examine the role of ocular sympathetic activity in the enlargement of the rabbit eyeball during postnatal growth... - Twenty-four-hour intraocular pressure pattern associated with early glaucomatous changesJohn H K Liu
Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093, USA
Invest Ophthalmol Vis Sci 44:1586-90. 2003.... 
Effects of aging on corneal biomechanical properties and their impact on 24-hour measurement of intraocular pressureTeruyo Kida
Hamilton Glaucoma Center, Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093, USA
Am J Ophthalmol 146:567-572. 2008..To study the effects of aging on corneal biomechanical properties and their impact on 24-hour measurement of intraocular pressure (IOP)...- Association of central corneal thickness and 24-hour intraocular pressure fluctuationSameh Mosaed
Department of Ophthalmology, University of California, Irvine, USA
J Glaucoma 17:85-8. 2008..To evaluate the association between office-hour central corneal thickness (CCT) and 24-hour intraocular pressure (IOP) fluctuation in patients with glaucoma... - Effect of laser trabeculoplasty on nocturnal intraocular pressure in medically treated glaucoma patientsAlexander C Lee
Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093 0946, USA
Ophthalmology 114:666-70. 2007..To evaluate the effects of laser trabeculoplasty on 24-hour intraocular pressure (IOP) in a group of medically treated open-angle glaucoma patients... - Effect of 24-hour corneal biomechanical changes on intraocular pressure measurementTeruyo Kida
Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093-0946, USA
Invest Ophthalmol Vis Sci 47:4422-6. 2006..The twenty-four-hour change in corneal viscoelasticity was not significant. There was no evidence that the 24-hour change in IOP was due to the change in corneal biomechanical properties... - Circadian variation of mouse aqueous humor proteinLinda X Zhou
Department of Ophthalmology, University of California, San Diego, La Jolla, CA 92093-0946, USA
Mol Vis 12:639-43. 2006..A similar diurnal/nocturnal decrease of aqueous humor protein concentration occurs in the CBA/CaJ mouse strain, indicating that this change of aqueous humor protein is unrelated to the diurnal/nocturnal pattern of IOP... - Sustained effect of travoprost on diurnal and nocturnal intraocular pressureArthur J Sit
Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, 92093, USA
Am J Ophthalmol 141:1131-3. 2006..CONCLUSIONS: IOP lowering effect after omission of one to two doses of travoprost is attenuated in the diurnal period but sustained in the nocturnal period, the time corresponding to the highest baseline habitual IOP... - Nocturnal rhythms of intraocular pressureRobert N Weinreb
Arch Ophthalmol 124:269-70. 2006 - Correlation between office and peak nocturnal intraocular pressures in healthy subjects and glaucoma patientsSameh Mosaed
Hamilton Glaucoma Center, Department of Ophthalmology, University of California, San Diego, La Jolla, California 92093-0946, USA
Am J Ophthalmol 139:320-4. 2005..Supine IOP measurements estimate peak nocturnal IOP better than sitting measurements. This estimation may provide the clinician with valuable information regarding the nocturnal IOP peak in glaucoma patients... - Comparison of the nocturnal effects of once-daily timolol and latanoprost on intraocular pressureJohn H K Liu
Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0946, USA
Am J Ophthalmol 138:389-95. 2004..To compare the nocturnal effects of once-daily timolol and latanoprost on intraocular pressure (IOP) in patients with ocular hypertension or early glaucomatous changes... - Asymmetry of right versus left intraocular pressures over 24 hours in glaucoma patientsArthur J Sit
Hamilton Glaucoma Center and Department of Ophthalmology, University of California San Diego, La Jolla, California 92093-0946, USA
Ophthalmology 113:425-30. 2006.... - Telemetric monitoring of 24 h intraocular pressure in conscious and freely moving C57BL/6J and CBA/CaJ miceRuixia Li
Hamilton Glaucoma Center and Department of Ophthalmology, University of California, San Diego, La Jolla, CA 92093 0946, USA
Mol Vis 14:745-9. 2008..To study change patterns of 24 h intraocular pressure (IOP) in conscious and freely moving mice using telemetry...
Research Grants
- REGULATION OF INTRAOCULAR PRESSURE AND OCULAR BLOOD FLOWJohn Liu; Fiscal Year: 2006..New knowledge of ocular blood flow and IOP in patients would have implications for the better diagnosis and treatment of glaucoma. ..
- REGULATION OF INTRAOCULAR PRESSURE AND OCULAR BLOOD FLOWJohn Liu; Fiscal Year: 2003..New knowledge of ocular blood flow and IOP in patients would have implications for the better diagnosis and treatment of glaucoma. ..
- ENDOGENOUS REGULATION OF INTRAOCULAR PRESSUREJohn Liu; Fiscal Year: 2002..This information should be useful for the development of antiglaucoma medicines. The human studies may lead to further studies in glaucoma patients and possibly a refinement of glaucoma therapy. ..
- ENDOGENOUS REGULATION OF AQUEOUS HUMOR DYNAMICSJohn Liu; Fiscal Year: 1993..This new knowledge should benefit relevant research in other species and help to refine the rationale for developing more effective antiglaucoma treatment...
- ENDOGENOUS REGULATION OF INTRAOCULAR PRESSUREJohn Liu; Fiscal Year: 1999..This information should be useful for the development of antiglaucoma medicines. The human studies may lead to further studies in glaucoma patients and possibly a refinement of glaucoma therapy. ..
- REGULATION OF INTRAOCULAR PRESSURE AND OCULAR BLOOD FLOWJohn Liu; Fiscal Year: 2007..New knowledge of ocular blood flow and lOP in patients would have implications for the better diagnosis and treatment of glaucoma. ..