Irene Litvan

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines
    Irene Litvan
    Division of Movement Disorders, Department of Neurology, University of Louisville, Louisville, Kentucky, USA
    Mov Disord 27:349-56. 2012
  2. pmc The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study
    Jeanne C Latourelle
    Department of Neurology, Boston University School of Medicine, Boston University, Boston, MA, USA
    BMC Med 6:32. 2008
  3. ncbi request reprint The etiopathogenesis of Parkinson disease and suggestions for future research. Part II
    Irene Litvan
    University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    J Neuropathol Exp Neurol 66:329-36. 2007
  4. pmc MDS Task Force on mild cognitive impairment in Parkinson's disease: critical review of PD-MCI
    Irene Litvan
    Division of Movement Disorders, Department of Neurology, University of Louisville, Louisville, Kentucky, USA
    Mov Disord 26:1814-24. 2011
  5. pmc Executive dysfunction is the primary cognitive impairment in progressive supranuclear palsy
    Adam Gerstenecker
    Department of Psychological and Brain Sciences, University of Louisville, Louisville, KY 40292 USA
    Arch Clin Neuropsychol 28:104-13. 2013
  6. doi request reprint H1/H1 genotype influences symptom severity in corticobasal syndrome
    Irene Litvan
    Division of Movement Disorders, Department of Neurology, University of Louisville, Louisville, Kentucky 40202, USA
    Mov Disord 25:760-3. 2010
  7. pmc Functional impairment in progressive supranuclear palsy
    Kevin Duff
    Department of Neurology, University of Utah, Salt Lake City, USA
    Neurology 80:380-4. 2013
  8. ncbi request reprint Alzheimer's disease presenting as corticobasal syndrome
    Pratap Chand
    Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Mov Disord 21:2018-22. 2006
  9. doi request reprint Cognitive and neuropsychiatric effects of subthalamotomy for Parkinson's disease
    Scott Bickel
    Division of Movement Disorders, Department of Neurology, University of Louisville School of Medicine, Frazier Rehab Neuroscience Institute, 220 Abraham Flexner Way, Ste 1503, Louisville, KY 40202, USA
    Parkinsonism Relat Disord 16:535-9. 2010
  10. doi request reprint Brain-lung-thyroid disease: clinical features of a kindred with a novel thyroid transcription factor 1 mutation
    Joseph M Ferrara
    Division of Movement Disorders, Department of Neurology, University of Louisville, Louisville, Kentucky, USA
    J Child Neurol 27:68-73. 2012

Collaborators

Detail Information

Publications22

  1. pmc Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines
    Irene Litvan
    Division of Movement Disorders, Department of Neurology, University of Louisville, Louisville, Kentucky, USA
    Mov Disord 27:349-56. 2012
    ....
  2. pmc The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study
    Jeanne C Latourelle
    Department of Neurology, Boston University School of Medicine, Boston University, Boston, MA, USA
    BMC Med 6:32. 2008
    ..Studies of the penetrance of LRRK2 mutations have produced a wide range of estimates, possibly due to differences in study design and recruitment, including in particular differences between samples of familial PD versus sporadic PD...
  3. ncbi request reprint The etiopathogenesis of Parkinson disease and suggestions for future research. Part II
    Irene Litvan
    University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    J Neuropathol Exp Neurol 66:329-36. 2007
    ..Topics reviewed in Part II are genetics, animal models, and oxidative stress...
  4. pmc MDS Task Force on mild cognitive impairment in Parkinson's disease: critical review of PD-MCI
    Irene Litvan
    Division of Movement Disorders, Department of Neurology, University of Louisville, Louisville, Kentucky, USA
    Mov Disord 26:1814-24. 2011
    ....
  5. pmc Executive dysfunction is the primary cognitive impairment in progressive supranuclear palsy
    Adam Gerstenecker
    Department of Psychological and Brain Sciences, University of Louisville, Louisville, KY 40292 USA
    Arch Clin Neuropsychol 28:104-13. 2013
    ..These results have important clinical implications for providers following patients with PSP...
  6. doi request reprint H1/H1 genotype influences symptom severity in corticobasal syndrome
    Irene Litvan
    Division of Movement Disorders, Department of Neurology, University of Louisville, Louisville, Kentucky 40202, USA
    Mov Disord 25:760-3. 2010
    ..ApoE inheritance did not influence cognition...
  7. pmc Functional impairment in progressive supranuclear palsy
    Kevin Duff
    Department of Neurology, University of Utah, Salt Lake City, USA
    Neurology 80:380-4. 2013
    ..The current study sought to describe the functional profiles of patients with early-stage progressive supranuclear palsy (PSP) in a large prospective, multisite study...
  8. ncbi request reprint Alzheimer's disease presenting as corticobasal syndrome
    Pratap Chand
    Department of Neurology, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Mov Disord 21:2018-22. 2006
    ..The videotaped clinical features, neuropsychological aspects, and neuropathological correlates are presented and discussed...
  9. doi request reprint Cognitive and neuropsychiatric effects of subthalamotomy for Parkinson's disease
    Scott Bickel
    Division of Movement Disorders, Department of Neurology, University of Louisville School of Medicine, Frazier Rehab Neuroscience Institute, 220 Abraham Flexner Way, Ste 1503, Louisville, KY 40202, USA
    Parkinsonism Relat Disord 16:535-9. 2010
    ..The results of this proof-of-concept pilot study suggest the need for larger, long-term, randomized controlled studies to assess motor, neuropsychiatric, behavioral and radiologic correlations after subthalamotomies...
  10. doi request reprint Brain-lung-thyroid disease: clinical features of a kindred with a novel thyroid transcription factor 1 mutation
    Joseph M Ferrara
    Division of Movement Disorders, Department of Neurology, University of Louisville, Louisville, Kentucky, USA
    J Child Neurol 27:68-73. 2012
    ..The unusual therapeutic response seen in our patients and others may help elucidate how disease-related migratory deficits affect neural pathways associated with motor control...
  11. doi request reprint Annonacin in Asimina triloba fruit: implication for neurotoxicity
    Lisa F Potts
    Department of Anatomical Sciences and Neurobiology, University of Louisville, United States
    Neurotoxicology 33:53-8. 2012
    ..This study determined whether annonacin is in the pawpaw fruit pulp and whether it or the crude ethyl acetate extract is toxic to cortical neurons...
  12. doi request reprint Unraveling progressive supranuclear palsy: from the bedside back to the bench
    David J Houghton
    Division of Movement Disorders, Department of Neurology, University of Louisville, Louisville, KY, USA
    Parkinsonism Relat Disord 13:S341-6. 2007
    ..31 to be associated with PSP, while the H2 haplotype seems protective. With greater knowledge of the molecular and genetic aspects of PSP, we can expect future diagnostic and therapeutic challenges to be more effectively met...
  13. doi request reprint Rapidly progressive atypical parkinsonism associated with frontotemporal lobar degeneration and motor neuron disease
    Alberto J Espay
    Department of Neurology, Movement Disorders Center, The Neuroscience Institute, University of Cincinnati, Cincinnati, Ohio, USA
    J Neurol Neurosurg Psychiatry 82:751-3. 2011
    ..To report the rare but distinct clinical and neuropathological phenotype of non-familial, rapidly progressive parkinsonism and dementia associated with frontotemporal lobar degeneration with motor neuron disease (FTLD-MND)...
  14. pmc Polymorphic genes of detoxification and mitochondrial enzymes and risk for progressive supranuclear palsy: a case control study
    Lisa F Potts
    Department of Anatomical Sciences and Neurobiology, University of Louisville, KY, USA
    BMC Med Genet 13:16. 2012
    ....
  15. pmc Parkinsonism and frontotemporal dementia: the clinical overlap
    Alberto J Espay
    Department of Neurology, Movement Disorders Center, UC Neuroscience Institute, University of Cincinnati, Cincinnati, OH, USA
    J Mol Neurosci 45:343-9. 2011
    ..This gap is critical to bridge in order to allow testing of novel biological therapies that may slow the progression of these proteinopathies...
  16. ncbi request reprint Update of atypical Parkinsonian disorders
    Irene Litvan
    Department of Neurology, University of Louisville, Louisville, Kentucky 40202, USA
    Curr Opin Neurol 20:434-7. 2007
    ..This timely update discusses novel diagnostic approaches, recently identified genes, and innovative experimental symptomatic treatments for these devastating disorders...
  17. pmc Cytokine expression and microglial activation in progressive supranuclear palsy
    Rafael Fernandez-Botran
    Department of Pathology and Laboratory Medicine, School of Medicine, University of Louisville, Louisville, KY 40292, USA
    Parkinsonism Relat Disord 17:683-8. 2011
    ..If so, the use of cytokine-inhibitors and/or other anti-inflammatory agents may be able to slow disease progression in PSP...
  18. pmc A recommended scale for cognitive screening in clinical trials of Parkinson's disease
    Kelvin L Chou
    Department of Neurology, University of Michigan, Ann Arbor, Michigan 48109 5316, USA
    Mov Disord 25:2501-7. 2010
    ..Widespread adoption of a single instrument such as the MoCA in clinical trials can improve comparability between research studies on PD...
  19. ncbi request reprint The etiopathogenesis of Parkinson disease and suggestions for future research. Part I
    Irene Litvan
    University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    J Neuropathol Exp Neurol 66:251-7. 2007
  20. pmc Huntington CAG repeat size does not modify onset age in familial Parkinson's disease: the GenePD study
    Christopher F McNicoll
    Department of Neurology, Boston University School of Medicine, Boston University, Boston, Massachusetts 02118, USA
    Mov Disord 23:1596-601. 2008
    ..No relation between the HD CAG repeat size and the age at onset for PD was found in this sample of familial PD...
  21. ncbi request reprint Update on progressive supranuclear palsy
    Irene Litvan
    Movement Disorder Program, Department of Neurology, University of Louisville School of Medicine, A Building, Room 113, 500 South Preston Street, Louisville, KY 40202, USA
    Curr Neurol Neurosci Rep 4:296-302. 2004
    ..These advances are explained in detail in this review...
  22. ncbi request reprint Update on epidemiological aspects of progressive supranuclear palsy
    Irene Litvan
    Movement Disorder Program, University of Louisville School of Medicine, Louisville, Kentucky, USA
    Mov Disord 18:S43-50. 2003
    ..The possible role of chemicals in the diet or occupation, hypertension, traumatic brain injury, coffee, and inflammation or oxidative injury are reviewed...