R R Little

Summary

Affiliation: University of Missouri
Country: USA

Publications

  1. ncbi request reprint The importance of precision for hemoglobin A1c measurement
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, Missouri 65212, USA
    Diabetes Technol Ther 5:979-81. 2003
  2. ncbi request reprint Effects of hemoglobin C and S traits on eight glycohemoglobin methods
    William L Roberts
    University of Utah, Department of Pathology, Salt Lake City, UT 84132, USA
    Clin Chem 48:383-5. 2002
  3. doi request reprint Measurement of Hba(1C) in patients with chronic renal failure
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, One Hospital Dr, Columbia, MO 65212, USA
    Clin Chim Acta 418:73-6. 2013
  4. doi request reprint The long and winding road to optimal HbA1c measurement
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, One Hospital Dr, Columbia, MO 65212, USA
    Clin Chim Acta 418:63-71. 2013
  5. pmc Analysis of the accuracy and precision of the Axis-Shield Afinion hemoglobin A1c measurement device
    Randie R Little
    Department of Pathology and Anatomical Sciences, Columbia, Missouri 65212, USA
    J Diabetes Sci Technol 6:387-8. 2012
  6. pmc Usefulness of glycated albumin assay for diabetes monitoring
    Randie R Little
    Department of Pathology and Anatomical Sciences, Columbia School of Medicine, University of Missouri, Columbia, Missouri 65212, USA
    J Diabetes Sci Technol 5:1463-5. 2011
  7. ncbi request reprint Validation by a mass spectrometric reference method of use of boronate affinity chromatography to measure glycohemoglobin in the presence of hemoglobin S and C traits
    Randie R Little
    University of Missouri Columbia School of Medicine, Department of Pathology and Anatomical Sciences, Columbia, MO 65212, USA
    Clin Chem 51:264-5. 2005
  8. ncbi request reprint Effects of sample storage conditions on glycated hemoglobin measurement: evaluation of five different high performance liquid chromatography methods
    Randie R Little
    Department of Pathology, University of Missouri School of Medicine, Columbia, Missouri 65212, USA
    Diabetes Technol Ther 9:36-42. 2007
  9. doi request reprint Standardization of C-peptide measurements
    Randie R Little
    Diabetes Diagnostic Laboratory, Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO 65212, USA
    Clin Chem 54:1023-6. 2008
  10. doi request reprint Effects of hemoglobin (Hb) E and HbD traits on measurements of glycated Hb (HbA1c) by 23 methods
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri Columbia School of Medicine, Columbia, MO 65212, USA
    Clin Chem 54:1277-82. 2008

Collaborators

Detail Information

Publications34

  1. ncbi request reprint The importance of precision for hemoglobin A1c measurement
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, Missouri 65212, USA
    Diabetes Technol Ther 5:979-81. 2003
  2. ncbi request reprint Effects of hemoglobin C and S traits on eight glycohemoglobin methods
    William L Roberts
    University of Utah, Department of Pathology, Salt Lake City, UT 84132, USA
    Clin Chem 48:383-5. 2002
  3. doi request reprint Measurement of Hba(1C) in patients with chronic renal failure
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, One Hospital Dr, Columbia, MO 65212, USA
    Clin Chim Acta 418:73-6. 2013
    ..There is also concern that HbA1c may give low results in these patients due to shortened erythrocyte survival...
  4. doi request reprint The long and winding road to optimal HbA1c measurement
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, One Hospital Dr, Columbia, MO 65212, USA
    Clin Chim Acta 418:63-71. 2013
    ..Here, we review the past, present and future of HbA1c standardization and describe the current status of HbA1c testing, including limitations that healthcare providers need to be aware of when interpreting HbA1c results...
  5. pmc Analysis of the accuracy and precision of the Axis-Shield Afinion hemoglobin A1c measurement device
    Randie R Little
    Department of Pathology and Anatomical Sciences, Columbia, Missouri 65212, USA
    J Diabetes Sci Technol 6:387-8. 2012
    ..Although they conclude that the Afinion exhibits adequate performance, they do not evaluate lot-to-lot variability. As with laboratory methods, potential assay interferences must also be considered...
  6. pmc Usefulness of glycated albumin assay for diabetes monitoring
    Randie R Little
    Department of Pathology and Anatomical Sciences, Columbia School of Medicine, University of Missouri, Columbia, Missouri 65212, USA
    J Diabetes Sci Technol 5:1463-5. 2011
    ..Once the utility of glycated albumin measurement is clearly defined and its use is accepted for diabetes care, standardization may be warranted...
  7. ncbi request reprint Validation by a mass spectrometric reference method of use of boronate affinity chromatography to measure glycohemoglobin in the presence of hemoglobin S and C traits
    Randie R Little
    University of Missouri Columbia School of Medicine, Department of Pathology and Anatomical Sciences, Columbia, MO 65212, USA
    Clin Chem 51:264-5. 2005
  8. ncbi request reprint Effects of sample storage conditions on glycated hemoglobin measurement: evaluation of five different high performance liquid chromatography methods
    Randie R Little
    Department of Pathology, University of Missouri School of Medicine, Columbia, Missouri 65212, USA
    Diabetes Technol Ther 9:36-42. 2007
    ..Glycated hemoglobin, reported as hemoglobin A1c (HbA1c), is widely used as a measure of long-term glycemic control in patients with diabetes. The accuracy of measurements depends in part on proper storage of the sample prior to analysis...
  9. doi request reprint Standardization of C-peptide measurements
    Randie R Little
    Diabetes Diagnostic Laboratory, Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO 65212, USA
    Clin Chem 54:1023-6. 2008
    ..We assessed within- and between-laboratory imprecision of C-peptide assays and determined whether serum calibrators with values assigned by mass spectrometry could be used to harmonize C-peptide results...
  10. doi request reprint Effects of hemoglobin (Hb) E and HbD traits on measurements of glycated Hb (HbA1c) by 23 methods
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri Columbia School of Medicine, Columbia, MO 65212, USA
    Clin Chem 54:1277-82. 2008
    ..HbE and HbD are the second and fourth most common Hb variants worldwide. We investigated the accuracy of HbA(1c) measurement in the presence of HbE and/or HbD traits...
  11. pmc A review of variant hemoglobins interfering with hemoglobin A1c measurement
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, MO 65212, USA
    J Diabetes Sci Technol 3:446-51. 2009
    ..Laboratorians should be aware of the limitations of their method with respect to these interferences...
  12. ncbi request reprint Glycated hemoglobin standardization--National Glycohemoglobin Standardization Program (NGSP) perspective
    Randie R Little
    Department of Pathology, University of Missouri School of Medicine, Columbia, MO 65212, USA
    Clin Chem Lab Med 41:1191-8. 2003
    ..8% HbA1c from the NGSP target at all HbA1c concentrations. The vast majority of laboratories in the US are now reporting results that are traceable to DCCT/UKPDS outcomes...
  13. pmc Analysis of point-of-care and over-the-counter testing methods for hemoglobin A1c: how good do they need to be?
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri Columbia School of Medicine, Columbia, Missouri 65212, USA
    J Diabetes Sci Technol 4:1504-6. 2010
    ....
  14. doi request reprint Status of hemoglobin A1c measurement and goals for improvement: from chaos to order for improving diabetes care
    Randie R Little
    Diabetes Diagnostic Laboratory M767, Department of Pathology and Anatomical Sciences, University of Missouri Columbia School of Medicine, Columbia, MO 65212, USA
    Clin Chem 57:205-14. 2011
    ..The National Glycohemoglobin Standardization Program (NGSP) was implemented in 1996 to standardize Hb A(1c) results to those of the DCCT/UKPDS...
  15. ncbi request reprint Can glycohemoglobin be used to assess glycemic control in patients with chronic renal failure?
    Randie R Little
    Department of Child Health, University of Missouri School of Medicine, 1 Hospital Dr, Columbia, MO 65212, USA
    Clin Chem 48:784-6. 2002
  16. ncbi request reprint The national glycohemoglobin standardization program: a five-year progress report
    R R Little
    Department of Child Health, University of Missouri School of Medicine, 1 Hospital Dr, Columbia, MO 65212, USA
    Clin Chem 47:1985-92. 2001
    ..This program was implemented in 1996 by the National Glycohemoglobin Standardization Program (NGSP) Steering Committee...
  17. ncbi request reprint Analysis: point-of-care testing for glycated hemoglobin (GHB)
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, Missouri 65212, USA
    Diabetes Technol Ther 7:913-5. 2005
  18. ncbi request reprint Use of GHb (HbA1c) in screening for undiagnosed diabetes in the U.S. population
    C L Rohlfing
    Department of Child Health, University of Missouri School of Medicine, Columbia 65203, USA
    Diabetes Care 23:187-91. 2000
    ..To evaluate the use of GHb as a screening test for undiagnosed diabetes (fasting plasma glucose > or =7.0 mmol/l) in a representative sample of the U.S. population...
  19. ncbi request reprint Defining the relationship between plasma glucose and HbA(1c): analysis of glucose profiles and HbA(1c) in the Diabetes Control and Complications Trial
    Curt L Rohlfing
    Department of Child Health, University of Missouri School of Medicine, 1 Hospital Drive M772, Columbia, MO 65203, USA
    Diabetes Care 25:275-8. 2002
    ..To define the relationship between HbA(1c) and plasma glucose (PG) levels in patients with type 1 diabetes using data from the Diabetes Control and Complications Trial (DCCT)...
  20. ncbi request reprint Effects of hemoglobin C and S traits on glycohemoglobin measurements by eleven methods
    William L Roberts
    Department of Pathology, ARUP Institute for Clinical and Experimental Pathology, University of Utah, Salt Lake City, UT 84108, USA
    Clin Chem 51:776-8. 2005
  21. doi request reprint HbA1c: how do we measure it and what does it mean?
    Randie R Little
    Department of Pathology and Anatomical Sciences, University of Missouri School of Medicine, Columbia, Missouri, USA
    Curr Opin Endocrinol Diabetes Obes 16:113-8. 2009
    ..Description of recent developments in the standardization of HbA1c measurement and interpretation of HbA1c results...
  22. doi request reprint Effects of hemoglobin C and S traits on the results of 14 commercial glycated hemoglobin assays
    Shella K Mongia
    Department of Pathology, University of Utah, Salt Lake City, UT, USA
    Am J Clin Pathol 130:136-40. 2008
    ..6% at 6% HbA1c). One immunoassay method exhibited clinically significant differences owing to the presence of HbC and HbS traits...
  23. ncbi request reprint Tests of glycemia in diabetes
    David E Goldstein
    Department of Child Health, University of Missouri School of Medicine, Columbia, MO 65212, USA
    Diabetes Care 27:1761-73. 2004
  24. doi request reprint The effect of elevated fetal hemoglobin on hemoglobin A1c results: five common hemoglobin A1c methods compared with the IFCC reference method
    Curt L Rohlfing
    Departments of Pathology and Anatomical Sciences, Child Health and Medicine, University of Missouri, Columbia School of Medicine, Columbia, MO 65212, USA
    Am J Clin Pathol 129:811-4. 2008
    ..Physicians and laboratory professionals need to be aware of potential interference from elevated HbF levels that could affect HbA1c results, including those from boronate-affinity methods...
  25. ncbi request reprint Effects of beta thalassemia minor on results of six glycated hemoglobin methods
    Christopher Polage
    Department of Pathology, University of Utah, Salt Lake City, UT 84132, USA
    Clin Chim Acta 350:123-8. 2004
    ..There are conflicting reports about the effect of BTM on glycated hemoglobin (gHb) measurements. We evaluated 6 gHb methods using samples from non-diabetic subjects with BTM...
  26. ncbi request reprint International comparison of C-peptide measurements
    Hsiao Mei Wiedmeyer
    Department of Pathology and Anatomical Sciences, University of Missouri Columbia School of Medicine, Columbia, MO 65212, USA
    Clin Chem 53:784-7. 2007
    ..We assessed the comparability of C-peptide results obtained with different methods and by different laboratories and determined whether C-peptide results could be harmonized by normalization with a WHO reference reagent or with plasma...
  27. ncbi request reprint Determination of glycated hemoglobin in clinically silent hemoglobin variants
    Wolfgang J Schnedl
    Department of Internal Medicine, Medical University, School of Medicine, Graz, Austria
    Diabetes Metab Res Rev 20:460-5. 2004
    ..Evaluation of glycated hemoglobin determination methods in patients with clinically silent hemoglobin variants...
  28. ncbi request reprint Trends in A1C concentrations among U.S. adults with diagnosed diabetes from 1999 to 2004
    Earl S Ford
    Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Diabetes Care 31:102-4. 2008
  29. ncbi request reprint Tests of glycemia in diabetes
    David E Goldstein
    Diabetes Care 26:S106-8. 2003
  30. ncbi request reprint Laboratory testing for glycated hemoglobin in the general community: are we following the clinical recommendations?
    Todd S Harwell
    Diabetes Technol Ther 4:859-61. 2002
  31. ncbi request reprint Testing for microalbuminuria in 2002: barriers to implementing current guidelines
    Todd S Harwell
    Montana Department of Public Health and Human Services, Helena, MT 59620 2951, USA
    Am J Kidney Dis 42:245-8. 2003
    ..Testing for microalbuminuria is recommended to detect early kidney damage in patients with diabetes or other diseases. However, few studies have examined laboratory practices for microalbuminuria testing in the general community...
  32. ncbi request reprint Tests of glycemia in diabetes
    David E Goldstein
    Diabetes Care 27:S91-3. 2004
  33. ncbi request reprint Global standardization of glycated hemoglobin measurement: the position of the IFCC Working Group
    Andrea Mosca
    Centre for Metrological Traceability in Laboratory Medicine CIRME, Dept Science and Biomedical Technology, University of Milano, Italy
    Clin Chem Lab Med 45:1077-80. 2007
    ..The IFCC WG-HbA1c recommends maintaining the use of the name HbA1c in clinical practice...
  34. ncbi request reprint Trends in hyperinsulinemia among nondiabetic adults in the U.S
    Chaoyang Li
    Centers for Disease Control and Prevention, 4770 Buford Hwy, MS K66, Atlanta, GA 30341, USA
    Diabetes Care 29:2396-402. 2006
    ..Our aim was to assess the trends in the mean concentrations of fasting serum insulin and the prevalence of hyperinsulinemia among nondiabetic adults during the periods of 1988-1994 and 1999-2002 in the U.S...