Research Topics
| R J LittleSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
The design and conduct of clinical trials to limit missing dataR J Little
Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA
Stat Med 31:3433-43. 2012..This article focuses on the panel's recommendations on the design and conduct of clinical trials to limit missing data. A companion paper addresses the panel's findings on analysis methods...
A method for longitudinal prospective evaluation of markers for a subsequent eventRoderick J Little
Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA
Am J Epidemiol 173:1380-7. 2011..Here, results from application of the method to 4 alternative proposed markers of the menopausal transition are compared with previous findings...
A comparison of methods for estimating the causal effect of a treatment in randomized clinical trials subject to noncomplianceRoderick J Little
Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA
Biometrics 65:640-9. 2009..Methods are illustrated on data from the Women Take Pride study, an assessment of behavioral treatments for women with heart disease...
A hot-deck multiple imputation procedure for gaps in longitudinal data on recurrent eventsRoderick J Little
Department of Biostatistics, University of Michigan, 1420 Washington Heights, Ann Arbor, MI 48109, U S A
Stat Med 27:103-20. 2008..A simulation study is presented to assess the statistical properties of the proposed procedure. Some possible extensions of the approach are also considered...
On summary measures analysis of the linear mixed effects model for repeated measures when data are not missing completely at randomR J Little
Department of Biostatistics and Institute for Social Research, University of Michigan, 1420 Washington Heights, Ann Arbor, MI 48109 2029, USA
Stat Med 18:2465-78. 1999..Analysis discarding the incomplete cases is even worse, with large biases and very poor confidence coverage...
On weighting the rates in non-response weightsRoderick J Little
Department of Biostatistics, University of Michigan, 1420 Washington Heights, Ann Arbor, MI 48109 2029, USA
Stat Med 22:1589-99. 2003..Otherwise, response propensity weighting can be applied...
Causal effects in clinical and epidemiological studies via potential outcomes: concepts and analytical approachesR J Little
University of Michigan, Ann Arbor 48109 2029, USA
Annu Rev Public Health 21:121-45. 2000....
A comparison of subset selection and analysis of covariance for the adjustment of confoundersR J Little
Department of Biostatistics, School of Public Health, University of Michigan, M4208 SPH II, 1420 Washington Heights, Ann Arbor, Michigan 48109 2029, USA
Psychol Methods 5:459-76. 2000..Specifically, a version of ANCOVA that models the relationship between the covariate and the outcome through cubic spline with fixed knots outperforms other methods in simulations...
Changes in young adult offense and crash patterns over timeP F Waller
Accid Anal Prev 33:117-28. 2001..The proportion of crashes that were at-fault did not decline over the sequence of crashes for an individual. Although crashes and offenses are positively correlated, they follow different trajectories over the early years of licensure...
Factors that influence successful training and faculty career development in hematology/oncology patient-oriented clinical researchScott D Gitlin
University of Michigan, Division of Hematology Oncology Department of Internal Medicine, Ann Arbor, 48109, USA
J Cancer Educ 20:72-8. 2005..We wanted to identify what factors promote career development in patient-oriented clinical research (POCR)...
Web-based smoking-cessation programs: results of a randomized trialVictor J Strecher
Center for Health Communications Research, University of Michigan School of Public Health, Ann Arbor, MI 48109 0471, USA
Am J Prev Med 34:373-81. 2008..This study aimed to (1) identify active psychosocial and communication components of a web-based smoking-cessation intervention and (2) examine the impact of increasing the tailoring depth on smoking cessation...
Change in estradiol and follicle-stimulating hormone across the early menopausal transition: effects of ethnicity and ageJohn F Randolph
Department of Obstetrics and Gynecology, School of Medicine, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA
J Clin Endocrinol Metab 89:1555-61. 2004....
Balanced centralized and distributed database design in a clinical research environmentN L Foster
Michigan Alzheimer s Disease Research Center and the Department of Neurology, University of Michigan, Ann Arbor, MI 48109, USA
Stat Med 19:1531-44. 2000..Balancing centralized and distributed designs for research databases enhance the accuracy and completeness of data collection and increases the use of data for research and clinical care...
A profile conditional likelihood approach for the semiparametric transformation regression model with missing covariatesH Y Chen
Division of Epidemiology and Biostatistics, School of Public Health, UIC 2121 West Taylor Street, Chicago, IL 60612, USA
Lifetime Data Anal 7:207-24. 2001..The potential application of the proposed method to the generalized probit model with missing continuous covariates is also outlined...
EMG variance during polysomnography as an assessment for REM sleep behavior disorderJoseph W Burns
Michigan Tech Research Institute, Michigan Technological University, Ann Arbor, MI 48105, USA
Sleep 30:1771-8. 2007..We therefore developed a computerized metric to assess EMG variance and compared the results to those previously published for visual scoring, bed partner-rated RBD symptom scores, and clinical assessments by sleep medicine specialists...
How well quantified is the limit of quantification?Ying Guo
Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA
Epidemiology 21:S10-6. 2010..A more plausible assumption is that there is measurement error throughout the measure's support...
