A M Lipton
Affiliation: University of Texas Southwestern Medical Center
- Differential activation on fMRI of monozygotic twins discordant for ADA M Lipton
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Texas 75390 9070, USA
Neurology 60:1713-6. 2003..Thus, fMRI may identify additional brain regions recruited in patients with AD to perform a given cognitive task...
- Lateralization on neuroimaging does not differentiate frontotemporal lobar degeneration from Alzheimer's diseaseAnne M Lipton
Alzheimer s Disease Centers at The University of Texas Southwestern Medical Center, Dallas, Tex, USA
Dement Geriatr Cogn Disord 17:324-7. 2004..Three of 4 FTLD cases had lateralized atrophy on CT. For the AD cases, 10/17 SPECTs, 2/7 MRIs, and 1/9 CTs showed lateralized findings. Of the neuroimaging modalities utilized, SPECT was the most sensitive in detecting lateralization...
- Frontotemporal lobar degeneration with motor neuron disease-type inclusions predominates in 76 cases of frontotemporal degenerationAnne M Lipton
Department of Neurology, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX 75390 9129, USA
Acta Neuropathol 108:379-85. 2004..Only eight (11%) were classified as Pick's disease. Several cases originally designated as DLDH could be reclassified as FTLD-MND-type based on current recommendations for classification of FTD...
- Frontal lobe dementia with novel tauopathy: sporadic multiple system tauopathy with dementiaE H Bigio
Department of Pathology, University of Texas Southwestern Medical School, Dallas 75390-9073, USA
J Neuropathol Exp Neurol 60:328-41. 2001..The unique cortical tau pathology in this case of sporadic multiple system tauopathy with dementia adds a new pathologic profile to the spectrum of tauopathies...
- Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementiasA M Lipton
Department of Neurology, University of Texas Southwestern Medical School, 5323 Harry Hines Blvd, Dallas, TX 75390-9073, USA
Arch Neurol 58:1233-9. 2001..Studies in larger numbers of FTD cases are planned with the goal of attaining statistically significant conclusions...
- Subscores of the FAB differentiate frontotemporal lobar degeneration from ADA M Lipton
Alzheimer's Disease Center, University of Texas Southwestern Medical Center, Dallas, TX 75390-8846, USA
Neurology 65:726-31. 2005..CONCLUSION: The Frontal Assessment Battery did not discriminate subjects with frontotemporal lobar degeneration from those with Alzheimer disease, though certain subtests may be helpful in differential diagnosis...
- Reduced hippocampal functional connectivity in Alzheimer diseaseGreg Allen
Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9127, USA
Arch Neurol 64:1482-7. 2007..To determine if functional connectivity of the hippocampus is reduced in patients with Alzheimer disease...
- Temporoparietal hypometabolism in frontotemporal lobar degeneration and associated imaging diagnostic errorsKyle B Womack
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9129, USA
Arch Neurol 68:329-37. 2011....
- Can alzheimer's disease and dementias with Lewy bodies be distinguished clinically?Myron F Weiner
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas 75390 9070, USA
J Geriatr Psychiatry Neurol 16:245-50. 2003..LB dementias differed from AD at initial evaluation, with more frequent hallucinations and delusions, EPSs, and seizures, and longitudinally in neuroleptic sensitivity, but the data did not distinguish LBV from DLBD...
- Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer diseaseGloria Lena Vega
Department of Clinical Nutrition, The Center for Human Nutrition, University of Texas Southwestern Medical Center and Nutrition and Metabolism Laboratory, Veterans Affairs Medical Center, Dallas 75390, USA
Arch Neurol 60:510-5. 2003..Most of plasma 24S-hydroxycholesterol is derived from brain cholesterol; consequently, plasma levels of the oxysterol reflect brain cholesterol catabolism...
- Vascular disease and risk factors, rate of progression, and survival in Alzheimer's diseaseDeepika Bhargava
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9070, USA
J Geriatr Psychiatry Neurol 19:78-82. 2006....
- An open-label study of memantine treatment in 3 subtypes of frontotemporal lobar degenerationAdam L Boxer
Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, CA 94143 1207, USA
Alzheimer Dis Assoc Disord 23:211-7. 2009..Memantine was well-tolerated in these subjects. Future placebo-controlled trials of memantine in FTLD are warranted and may have greater power to detect behavioral and cognitive effects if focused on the FTD and SD clinical syndromes...
- Convergence of connected language and SPECT in variants of frontotemporal lobar degenerationSandra B Chapman
Center for BrainHealth, The University of Texas at Dallas, 75235, USA
Alzheimer Dis Assoc Disord 19:202-13. 2005....
- MMSE scores decline at a greater rate in frontotemporal degeneration than in ADTiffany W Chow
Rotman Research Institute of Baycrest, University of Toronto Department of Medicine, Division of Neurology, Toronto, Canada
Dement Geriatr Cogn Disord 22:194-9. 2006..018). Changes in MMSE subscores paralleled the clinical diagnostic criteria for FTD. The more rapid progression on the language subscore was observed in both language and behavioral variants of FTD...
- Referral patterns for syndromes associated with frontotemporal lobar degenerationTiffany W Chow
The Rotman Research Institute, University of Toronto, Toronto, Ontario
Alzheimer Dis Assoc Disord 19:17-9. 2005..Clinics specializing in FTD recruit more language presentation cases. There were statistical but not clinically significant differences in ages at onset...