STEVEN EDWARD LIPSHULTZ

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. ncbi request reprint Can the consequences of universal cholesterol screening during childhood prevent cardiovascular disease and thus reduce long-term health care costs?
    Steven E Lipshultz
    Division of Cardiology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL 33101, USA
    Pediatr Endocrinol Rev 9:698-705. 2012
  2. pmc Cardiovascular effects in childhood cancer survivors treated with anthracyclines
    Vivian I Franco
    Division of Pediatric Clinical Research, Department of Pediatrics, University of Miami Miller School of Medicine, Medical Campus BCRI D820, 1580 NW 10th Avenue, 5th Floor, Miami, FL 33136, USA
    Cardiol Res Pract 2011:134679. 2011
  3. ncbi request reprint Risk stratification at diagnosis for children with hypertrophic cardiomyopathy: an analysis of data from the Pediatric Cardiomyopathy Registry
    Steven E Lipshultz
    University of Miami Miller School of Medicine, Miami, FL, USA Electronic address
    Lancet 382:1889-97. 2013
  4. pmc Cardiac effects in perinatally HIV-infected and HIV-exposed but uninfected children and adolescents: a view from the United States of America
    Steven E Lipshultz
    Department of Pediatrics, Jackson Memorial Medical Center and the Sylvester Comprehensive Cancer Center, Holtz Children s Hospital, University of Miami Miller School of Medicine, Miami, FL, USA
    J Int AIDS Soc 16:18597. 2013
  5. pmc Continuous Versus Bolus Infusion of Doxorubicin in Children With ALL: Long-term Cardiac Outcomes
    Steven E Lipshultz
    Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL 33101
    Pediatrics 130:1003-11. 2012
  6. doi request reprint HAART to heart: highly active antiretroviral therapy and the risk of cardiovascular disease in HIV-infected or exposed children and adults
    Steven E Lipshultz
    Department of Pediatrics D820, University of Miami Miller School of Medicine, PO Box 16820, Miami, FL 33101, USA
    Expert Rev Anti Infect Ther 10:661-74. 2012
  7. pmc Cardiovascular status of childhood cancer survivors exposed and unexposed to cardiotoxic therapy
    Steven E Lipshultz
    University of Miami Miller School of Medicine, Miami, FL 33101, USA
    J Clin Oncol 30:1050-7. 2012
  8. pmc Changes in cardiac biomarkers during doxorubicin treatment of pediatric patients with high-risk acute lymphoblastic leukemia: associations with long-term echocardiographic outcomes
    Steven E Lipshultz
    University of Miami Miller School of Medicine, Miami, FL 33101, USA
    J Clin Oncol 30:1042-9. 2012
  9. ncbi request reprint Pathophysiology of anthracycline- and radiation-associated cardiomyopathies: implications for screening and prevention
    M Jacob Adams
    Department of Community and Preventive Medicine, The University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Pediatr Blood Cancer 44:600-6. 2005
  10. pmc Clinical research directions in pediatric cardiology
    Steven E Lipshultz
    Department of Pediatrics, Division of Pediatric Clinical Research, University of Miami, Leonard M Miller School of Medicine, Miami, Florida 33101, USA
    Curr Opin Pediatr 21:585-93. 2009

Research Grants

  1. HAART Associated Cardiotoxicity in HIV-Infected Children
    Steven Lipshultz; Fiscal Year: 2006
  2. CARDIAC RISK FACTORS IN PEDIATRIC CANCER SURVIVORS
    Steven Lipshultz; Fiscal Year: 2001
  3. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2000
  4. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2007
  5. CARDIAC RISK FACTORS IN PEDIATRIC CANCER SURVIVORS
    Steven Lipshultz; Fiscal Year: 2000
  6. HAART Associated Cardiotoxicity in HIV-Infected Children
    Steven Lipshultz; Fiscal Year: 2004
  7. Cardiovascular Status of HAART-Exposed Infants/Children
    Steven Lipshultz; Fiscal Year: 2002
  8. Cardiovascular Status of HAART-Exposed Infants/Children
    Steven Lipshultz; Fiscal Year: 2004
  9. Primary Cardiomyopathies in Children: Research Directions & Strategies
    Steven Lipshultz; Fiscal Year: 2007
  10. HAART Associated Cardiotoxicity in HIV-Infected Children
    Steven Lipshultz; Fiscal Year: 2005

Collaborators

Detail Information

Publications61

  1. ncbi request reprint Can the consequences of universal cholesterol screening during childhood prevent cardiovascular disease and thus reduce long-term health care costs?
    Steven E Lipshultz
    Division of Cardiology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL 33101, USA
    Pediatr Endocrinol Rev 9:698-705. 2012
    ..This commentary discusses the medical, psychosocial and economic benefits and risks of universal cholesterol screening in children...
  2. pmc Cardiovascular effects in childhood cancer survivors treated with anthracyclines
    Vivian I Franco
    Division of Pediatric Clinical Research, Department of Pediatrics, University of Miami Miller School of Medicine, Medical Campus BCRI D820, 1580 NW 10th Avenue, 5th Floor, Miami, FL 33136, USA
    Cardiol Res Pract 2011:134679. 2011
    ..Here, we review the cardiovascular complications associated with the use of anthracyclines in treating malignancies in children and discuss methods for preventing, screening, and treating such complications in childhood cancer survivors...
  3. ncbi request reprint Risk stratification at diagnosis for children with hypertrophic cardiomyopathy: an analysis of data from the Pediatric Cardiomyopathy Registry
    Steven E Lipshultz
    University of Miami Miller School of Medicine, Miami, FL, USA Electronic address
    Lancet 382:1889-97. 2013
    ..Treatment of children with hypertrophic cardiomyopathy might be improved if the risk of death or heart transplantation could be predicted by risk factors present at the time of diagnosis...
  4. pmc Cardiac effects in perinatally HIV-infected and HIV-exposed but uninfected children and adolescents: a view from the United States of America
    Steven E Lipshultz
    Department of Pediatrics, Jackson Memorial Medical Center and the Sylvester Comprehensive Cancer Center, Holtz Children s Hospital, University of Miami Miller School of Medicine, Miami, FL, USA
    J Int AIDS Soc 16:18597. 2013
    ..Thus, multi-agent HIV therapies that help sustain life may also increase the risk of cardiovascular events and accelerated atherosclerosis...
  5. pmc Continuous Versus Bolus Infusion of Doxorubicin in Children With ALL: Long-term Cardiac Outcomes
    Steven E Lipshultz
    Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL 33101
    Pediatrics 130:1003-11. 2012
    ..Its effectiveness in reducing late cardiotoxicity in children remains uncertain. We determined continuous-infusion doxorubicin cardioprotective efficacy in long-term survivors of childhood acute lymphoblastic leukemia (ALL)...
  6. doi request reprint HAART to heart: highly active antiretroviral therapy and the risk of cardiovascular disease in HIV-infected or exposed children and adults
    Steven E Lipshultz
    Department of Pediatrics D820, University of Miami Miller School of Medicine, PO Box 16820, Miami, FL 33101, USA
    Expert Rev Anti Infect Ther 10:661-74. 2012
    ..Here, we review available research in this field and highlight the importance of understanding known complications and their mechanisms...
  7. pmc Cardiovascular status of childhood cancer survivors exposed and unexposed to cardiotoxic therapy
    Steven E Lipshultz
    University of Miami Miller School of Medicine, Miami, FL 33101, USA
    J Clin Oncol 30:1050-7. 2012
    ....
  8. pmc Changes in cardiac biomarkers during doxorubicin treatment of pediatric patients with high-risk acute lymphoblastic leukemia: associations with long-term echocardiographic outcomes
    Steven E Lipshultz
    University of Miami Miller School of Medicine, Miami, FL 33101, USA
    J Clin Oncol 30:1042-9. 2012
    ..Doxorubicin causes cardiac injury and cardiomyopathy in children with acute lymphoblastic leukemia (ALL). Measuring biomarkers during therapy might help individualize treatment by immediately identifying cardiac injury and cardiomyopathy...
  9. ncbi request reprint Pathophysiology of anthracycline- and radiation-associated cardiomyopathies: implications for screening and prevention
    M Jacob Adams
    Department of Community and Preventive Medicine, The University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Pediatr Blood Cancer 44:600-6. 2005
    ..Appropriate screening of the entire cardiovascular system should be performed because radiation and chemotherapy affect the entire system. Prevention recommendations focus on cardiomyopathy and coronary artery disease...
  10. pmc Clinical research directions in pediatric cardiology
    Steven E Lipshultz
    Department of Pediatrics, Division of Pediatric Clinical Research, University of Miami, Leonard M Miller School of Medicine, Miami, Florida 33101, USA
    Curr Opin Pediatr 21:585-93. 2009
    ..Renewed interest in federally funded clinical research makes it timely to propose a comprehensive research agenda that, with its associated rationale, will attract public funds for research into child cardiovascular health and disease...
  11. ncbi request reprint Chronic progressive cardiac dysfunction years after doxorubicin therapy for childhood acute lymphoblastic leukemia
    Steven E Lipshultz
    Department of Pediatrics D820, Miller School of Medicine at the University of Miami, Miami, FL 33101, USA
    J Clin Oncol 23:2629-36. 2005
    ..Cross-sectional studies show that cardiac abnormalities are common in long-term survivors of doxorubicin-treated childhood malignancies. Longitudinal data, however, are rare...
  12. ncbi request reprint Cardiac changes associated with growth hormone therapy among children treated with anthracyclines
    Steven E Lipshultz
    Department of Pediatrics, Miller School of Medicine, University of Miami, Holtz Children s Hospital, Sylvester Comprehensive Cancer Center, Miami, Florida, USA
    Pediatrics 115:1613-22. 2005
    ..Anthracycline-treated childhood cancer survivors frequently have reduced left ventricular (LV) wall thickness and contractility, and GH therapy may affect these factors...
  13. pmc Frequency of elevations in markers of cardiomyocyte damage in otherwise healthy newborns
    Steven E Lipshultz
    Department of Pediatrics, University of Miami Leonard M Miller School of Medicine, Miami, Florida, USA
    Am J Cardiol 102:761-6. 2008
    ..046), and elevated high-sensitivity C-reactive protein (r = 0.66, p = 0.005). In conclusion, clinically occult myocardial injury appears to occur in some healthy newborns, although whether it is pathologic or not remains to be determined...
  14. ncbi request reprint Frequency of clinically unsuspected myocardial injury at a children's hospital
    Steven E Lipshultz
    Department of Cardiology, Harvard Medical School, Boston, MA, USA
    Am Heart J 151:916-22. 2006
    ..Ill children are at risk but rarely screened for myocardial injury. The frequency of such injury in ill children is unknown. Elevated levels of plasma cardiac troponin I (cTnI) can detect subclinical myocardial injury...
  15. ncbi request reprint Exposure to anthracyclines during childhood causes cardiac injury
    Steven E Lipshultz
    Department of Pediatrics, and the Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Semin Oncol 33:S8-14. 2006
    ..001). Dexrazoxane was also shown to have no effect on the event-free survival rate at 2.5 years, emphasizing that it does not detrimentally affect the efficacy of anthracycline therapy...
  16. ncbi request reprint The relevance of information generated by in vitro experimental models to clinical doxorubicin cardiotoxicity
    Steven E Lipshultz
    Department of Pediatrics, Sylvester Comprehensive Cancer Center, University of Miami, Miller School of Medicine, Miami, FL, USA
    Leuk Lymphoma 47:1454-8. 2006
  17. doi request reprint Anthracycline associated cardiotoxicity in survivors of childhood cancer
    Steven E Lipshultz
    Department of Pediatrics, Leonard M Miller School of Medicine, University of Miami, Holtz Children s Hospital of the University of Miami Jackson Memorial Medical Center, Miami, FL 33101, USA
    Heart 94:525-33. 2008
  18. ncbi request reprint The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemia
    Steven E Lipshultz
    Department of Pediatrics, University of Miami School of Medicine, Holtz Children s Hospital of the University of Miami Jackson Memorial Medical Center and the Sylvester Comprehensive Cancer Center, Miami 33101, USA
    N Engl J Med 351:145-53. 2004
    ..Doxorubicin chemotherapy is very effective in children with acute lymphoblastic leukemia (ALL) but also injures myocardial cells. Dexrazoxane, a free-radical scavenger, may protect the heart from doxorubicin-associated damage...
  19. pmc Cardiac effects of antiretroviral therapy in HIV-negative infants born to HIV-positive mothers: NHLBI CHAART-1 (National Heart, Lung, and Blood Institute Cardiovascular Status of HAART Therapy in HIV-Exposed Infants and Children cohort study)
    Steven E Lipshultz
    Department of Pediatrics, University of Miami Miller School of Medicine, Miami, Florida 33101, USA
    J Am Coll Cardiol 57:76-85. 2011
    ..The aim of this study was to investigate the possible effects of antiretroviral therapy (ART) in utero on cardiac development and function in human immunodeficiency virus (HIV)-negative children...
  20. pmc Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial
    Steven E Lipshultz
    University of Miami, Leonard M Miller School of Medicine, Miami, FL, USA
    Lancet Oncol 11:950-61. 2010
    ..We aimed to establish the long-term effect of dexrazoxane on the subclinical state of cardiac health in survivors of childhood high-risk ALL 5 years after completion of doxorubicin treatment...
  21. ncbi request reprint Anthracycline-induced cardiotoxicity: course, pathophysiology, prevention and management
    Elly Barry
    Department of Pediatric Oncology, Dana Farber Cancer Institute Children s Hospital, Boston Harvard Medical School, 44 Binney Street, 3rd Floor, Boston, MA 02115, USA
    Expert Opin Pharmacother 8:1039-58. 2007
    ..These treatments include avoiding additional cardiotoxic regimens, controlling hypertension, lifestyle changes, medications and heart transplantation...
  22. ncbi request reprint Cardiovascular outcomes of pediatric seroreverters perinatally exposed to HAART: design of a longitudinal clinical study
    Jill E Lavigne
    University of Rochester, Rochester, NY, USA
    Cardiovasc Toxicol 4:187-97. 2004
    ..The cohorts are similar in terms of gender and race and the recruited subjects are representative of all eligible subjects in terms of exposure to HAART. Recruitment will continue into 2006...
  23. ncbi request reprint Serum cardiac troponin and subclinical cardiac status in pediatric chronic renal failure
    Steven E Lipshultz
    Department of Cardiology, Children s Hospital, Boston, Massachusetts, USA
    Pediatrics 112:79-86. 2003
    ..Pediatric patients are ideal for studies of the relationship between uremia and heart disease because they are unlikely to have cardiac risk factors other than uremia...
  24. doi request reprint Associations between neurohormonal and inflammatory activation and heart failure in children
    Christopher Ratnasamy
    Division of Pediatric Cardiology, Department of Pediatrics, Leonard M Miller School of Medicine, University of Miami, University of Miami Jackson Memorial Medical Center, Miami, FL 33101, USA
    Am Heart J 155:527-33. 2008
    ..We hypothesize that neuroendocrine and inflammatory activation also associate with symptom severity and echocardiographic measurements in pediatric HF...
  25. ncbi request reprint Anthracycline cardiotoxicity in long-term survivors of childhood cancer
    Rebecca E Scully
    Department of Pediatrics, Division of Pediatric Clinical Research, University of Miami Miller School of Medicine, Miami, FL 33101, USA
    Cardiovasc Toxicol 7:122-8. 2007
    ..Support and study of this population to decrease the morbidity and morality associated with anthracycline-induced cardiotoxicity is indicated in a time sensitive fashion...
  26. ncbi request reprint Long-term effects of treatments for childhood cancers
    Jorge A Alvarez
    Department of Pediatrics, University of Miami Jackson Memorial Medical Center, Miami, Florida, USA
    Curr Opin Pediatr 19:23-31. 2007
    ..We selectively review the negative late cardiac, endocrine, and neurological effects of childhood cancer and its treatments and comment on current research and recommendations for the care of long-term survivors of childhood cancer...
  27. pmc Biomarkers of vascular dysfunction in children infected with human immunodeficiency virus-1
    Tracie L Miller
    Division of Pediatric Clinical Research, Department of Pediatrics, Miller School of Medicine, University of Miami, Miami, FL, USA
    J Acquir Immune Defic Syndr 55:182-8. 2010
    ..We compared biomarkers of vascular dysfunction among HIV-infected children to a demographically similar group of uninfected children and determined factors associated with these biomarkers...
  28. doi request reprint Relationship between body mass index and metabolic syndrome risk factors among US 8- to 14-year-olds, 1999 to 2002
    Sarah E Messiah
    Department of Pediatrics, Division of Pediatric Clinical Research, University of Miami Leonard M Miller School of Medicine, Miami, FL 33101, USA
    J Pediatr 153:215-21. 2008
    ..To determine the prevalence of metabolic syndrome risk factors (MSRF) and examine the relationship between body mass index and the prevalence of >or=3 MSRF in 8- to 11- and 12- to 14-year-old age groups...
  29. doi request reprint An improved estimator for the hydration of fat-free mass from in vivo measurements subject to additive technical errors
    Daniel D Kinnamon
    Department of Pediatrics, University of Miami Miller School of Medicine, FL 33101, USA
    Physiol Meas 31:497-512. 2010
    ....
  30. pmc Risk factors for cardiovascular disease in children infected with human immunodeficiency virus-1
    Tracie L Miller
    Division of Pediatric Clinical Research, Department of Pediatrics, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    J Pediatr 153:491-7. 2008
    ....
  31. ncbi request reprint Incidence of cardiac abnormalities in children with human immunodeficiency virus infection: The prospective P2C2 HIV study
    Thomas J Starc
    Department of Pediatrics, Division of Pediatric Cardiology, Presbyterian Hospital Columbia University, College of Physicians and Surgeons, New York City, New York, USA
    J Pediatr 141:327-34. 2002
    ..9 years. Group II consisted of 600 HIV-exposed children enrolled prenatally or as neonates, of whom 93 were ultimately HIV-infected. The main outcome measures were echocardiographic indexes of left ventricular dysfunction...
  32. ncbi request reprint Usefulness of the pediatric electrocardiogram in detecting left ventricular hypertrophy: results from the Prospective Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2 HIV) multicenter study
    Shannon M Rivenes
    Department of Pediatrics, Division of Pediatric Cardiology, Baylor College of Medicine Texas Children s Hospital, Houston, Tex 77030, USA
    Am Heart J 145:716-23. 2003
    ..This study prospectively assesses the usefulness of the pediatric ECG as a screening modality for LVH...
  33. doi request reprint Body mass index, waist circumference, and cardiovascular risk factors in adolescents
    Sarah E Messiah
    Department of Pediatrics, Division of Pediatric Clinical Research, University of Miami Leonard M Miller School of Medicine, Miami, FL, USA
    J Pediatr 153:845-50. 2008
    ..To determine optimal threshold values for body mass index (BMI) and waist circumference (WC) for detecting cardiovascular disease (CVD) risk (as defined with >/=3 CVD risk factors [RFs]) in adolescents...
  34. ncbi request reprint Accelerated cardiovascular disease and myocardial infarction risk in patients with the human immunodeficiency virus
    Tanvi S Sharma
    University of Miami Miller School of Medicine, Miami, FL 33101, USA
    J Cardiometab Syndr 3:93-7. 2008
    ..Identifying, monitoring, and treating CVD risk factors in HIV-positive patients is vital to improving their lives and should become standard practice...
  35. pmc Serial measurements of serum NT-proBNP as markers of left ventricular systolic function and remodeling in children with heart failure
    Paolo G Rusconi
    Divisions of Pediatric Cardiology, Miami, FL, USA
    Am Heart J 160:776-83. 2010
    ..We determined whether changes in NT-proBNP level are associated with changes in symptoms and left ventricular (LV) systolic function and remodeling in children with HF secondary to dilated cardiomyopathy...
  36. doi request reprint Characteristics and determinants of adiposity in pediatric cancer survivors
    Tracie L Miller
    Batchelor Children s Research Institute, Division of Pediatric Clinical Research, Department of Pediatrics D820, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    Cancer Epidemiol Biomarkers Prev 19:2013-22. 2010
    ..Direct evaluations of adiposity and comparisons to contemporary controls that can differentiate recent trends in obesity from cancer-related treatments and sequelae are limited...
  37. ncbi request reprint Cardiometabolic disease in human immunodeficiency virus-infected children
    Tracie L Miller
    Division of Pediatric Clinical Research, Department of Pediatrics, Miller School of Medicine, University of Miami, Miami, FL, USA
    J Cardiometab Syndr 3:98-105. 2008
    ..Preventive care and interventions that include surveillance of nutrition and body composition, dietary counseling, exercise programs, and drug therapy should be considered standard care for all HIV-infected children...
  38. ncbi request reprint Doxorubicin administration by continuous infusion is not cardioprotective: the Dana-Farber 91-01 Acute Lymphoblastic Leukemia protocol
    Steven E Lipshultz
    Division of Pediatric Cardiology, Strong Children s Hospital and University of Rochester Medical Center, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Clin Oncol 20:1677-82. 2002
    ..We compared cardiac outcomes in children receiving bolus or continuous infusion of doxorubicin...
  39. ncbi request reprint Evaluation of coxsackievirus infection in children with human immunodeficiency virus type 1-associated cardiomyopathy
    Hal B Jenson
    Department of Pediatrics, MC 7811, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    J Infect Dis 185:1798-802. 2002
    ..These results do not identify a causal role for coxsackieviruses for cardiomyopathy in HIV-1-infected children...
  40. doi request reprint Absence of secondary malignant neoplasms in children with high-risk acute lymphoblastic leukemia treated with dexrazoxane
    Elly V Barry
    Departments of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    J Clin Oncol 26:1106-11. 2008
    ..We report the absence of an association of SMNs in children with acute lymphoblastic leukemia (ALL) treated on Dana-Farber Cancer Institute ALL Consortium Protocol 95-01...
  41. ncbi request reprint Cardiotoxicity of cancer chemotherapy: implications for children
    Valeriano C Simbre
    Division of Pediatric Cardiology, University of Rochester Medical Center and Golisano Children s Hospital at Strong, Rochester, New York, USA
    Paediatr Drugs 7:187-202. 2005
    ..Treatments include diuresis, afterload reduction, beta-adrenoceptor antagonists, and improving myocardial contractility...
  42. ncbi request reprint Radiation-associated cardiovascular disease
    M Jacob Adams
    Department of Pediatrics, Division of Pediatric Cardiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 631, Rochester, NY 14642, USA
    Crit Rev Oncol Hematol 45:55-75. 2003
    ..Long-term cardiac follow-up of these patients is therefore essential, and the range of appropriate cardiac screening is discussed, although no specific, evidence-based screening regimen was found in the literature...
  43. ncbi request reprint Cardiovascular disease and toxicities related to HIV infection and its therapies
    Karolina M Zareba
    University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    Expert Opin Drug Saf 4:1017-25. 2005
    ..Exercise, a nonpharmacological approach to treating HAART-associated metabolic syndrome, is also discussed...
  44. ncbi request reprint Cardiac management by pediatricians versus pediatric cardiologists in an inpatient academic center
    Jacques Benun
    Department of Pediatrics, Boston Medical Center, Boston, Mass, USA
    Am Heart J 145:424-9. 2003
    ..To study this strategy, we compared the management decisions of pediatricians with the recommendations of pediatric cardiologists who reviewed the records of the same patients...
  45. ncbi request reprint Maternal age and other predictors of newborn blood pressure
    Matthew W Gillman
    Department of Ambulatory Care and Prevention, Harvard Medical School Harvard Pilgrim Health Care, Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Pediatr 144:240-5. 2004
    ..To investigate perinatal predictors of newborn blood pressure...
  46. ncbi request reprint Cardiovascular effects of HAART in infants and children of HIV-infected mothers
    Karolina M Zareba
    University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Cardiovasc Toxicol 4:271-9. 2004
    ..Further studies are needed to explore the long-term effects and possible toxicities of prophylactic antiretroviral therapy on infants born to HIV-infected mothers...
  47. ncbi request reprint Radiation-associated cardiovascular disease: manifestations and management
    M Jacob Adams
    Department of Pediatrics, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Semin Radiat Oncol 13:346-56. 2003
    ..The broad range of radiation-associated cardiovascular disease makes it necessary for survivors to be examined with multiple screening modalities, although data do not exist to support definitive recommendations on test frequency...
  48. ncbi request reprint Mediators in HIV-associated cardiovascular disease: a focus on cytokines and genes
    Stacy D Fisher
    Department of Medicine, Cardiology Unit, University of Rochester Medical Center, Rochester, New York 14642, USA
    AIDS 17:S29-35. 2003
    ..In the present review, we discuss possible cytokine and gene-mediated effects on HIV-associated cardiovascular illness that may play a role in diagnosis, management, and therapy of HIV-associated heart failure...
  49. ncbi request reprint Body mass index as a function of length of United States residency among Haitian immigrant children
    Nancy Strickman-Stein
    Department of Epidemiology and Public Health, University of Miami, Leonard M Miller School of Medicine, Miami, Florida 33130, USA
    Ethn Dis 20:22-8. 2010
    ....
  50. ncbi request reprint Wise up: do not do it without protection!
    Stephen E Sallan
    Dana Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatr Blood Cancer 45:872-3. 2005
  51. ncbi request reprint Association between congenital cardiovascular malformations and neuroblastoma
    Rani E George
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA
    J Pediatr 144:444-8. 2004
    ..We explored the association between neuroblastoma and congenital cardiovascular malformations (CCM), previously described in case reports...
  52. ncbi request reprint Factors associated with establishing a causal diagnosis for children with cardiomyopathy
    Gerald F Cox
    Division of Genetics, Department of Medicine, Children s Hospital, Boston, Massachusetts, USA
    Pediatrics 118:1519-31. 2006
    ..The goal was to identify the clinical variables associated with establishing a cause of cardiomyopathy in children...
  53. pmc Maternal calcium intake and offspring blood pressure
    Matthew W Gillman
    Department of Ambulatory Care and Prevention, Harvard Medical School Harvard Pilgrim Health Care, Boston, Mass 02215, USA
    Circulation 110:1990-5. 2004
    ..Few data exist on the intergenerational influence of calcium intake during pregnancy on offspring blood pressure...
  54. ncbi request reprint Coronary artery calcifications in the long-term follow-up of Kawasaki disease
    Gul H Dadlani
    Congenital Heart Institute of Florida, All Children s Hospital, St Petersburg, Florida, USA
    Am Heart J 150:1016. 2005
    ..To determine if detection of coronary artery calcifications in patients with Kawasaki disease may serve as a noninvasive predictor of future coronary artery events...
  55. pmc Treating children with idiopathic dilated cardiomyopathy (from the Pediatric Cardiomyopathy Registry)
    William G Harmon
    Department of Pediatrics, University of Miami, Leonard M Miller School of Medicine, Miami, Florida, USA
    Am J Cardiol 104:281-6. 2009
    ..In conclusion, therapeutic clinical trials are strongly indicated because practice variation is substantial and medical outcomes in these children have not improved in the previous several decades...
  56. pmc Health effects of energy drinks on children, adolescents, and young adults
    Sara M Seifert
    Department of Pediatrics and Pediatric Integrative Medicine Program, University of Miami, Leonard M Miller School of Medicine, Miami, Florida 33101, USA
    Pediatrics 127:511-28. 2011
    ..To review the effects, adverse consequences, and extent of energy drink consumption among children, adolescents, and young adults...
  57. ncbi request reprint The incidence of pediatric cardiomyopathy in two regions of the United States
    Steven E Lipshultz
    Golisano Children s Hospital at Strong and University of Rochester Medical Center, and the Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    N Engl J Med 348:1647-55. 2003
    ..Population-based data on the incidence of pediatric cardiomyopathy are rare because of the lack of large, prospective studies...
  58. ncbi request reprint Cardiovascular status of infants and children of women infected with HIV-1 (P(2)C(2) HIV): a cohort study
    Steven E Lipshultz
    Division of Pediatric Cardiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
    Lancet 360:368-73. 2002
    ..Data from cross-sectional and short-term longitudinal studies have suggested that children infected with HIV-1 might have cardiovascular abnormalities. We aimed to investigate this hypothesis in a long-term cohort study...
  59. ncbi request reprint Predictors of cardiac morbidity and related mortality in children with acquired immunodeficiency syndrome
    Inas Al-Attar
    Department of Cardiology, Children s Hospital, Boston, Massachusetts, USA
    J Am Coll Cardiol 41:1598-605. 2003
    ..The aim of this study was to determine the prevalence of cardiovascular dysfunction and its predictors in children with acquired immunodeficiency syndrome (AIDS)...
  60. ncbi request reprint Cardiovascular status in long-term survivors of Hodgkin's disease treated with chest radiotherapy
    M Jacob Adams
    Department of Community and Preventive Medicine, University of Rochester School of Medicine and Dentistry, NY, USA
    J Clin Oncol 22:3139-48. 2004
    ..Cardiovascular status was assessed in 48 Hodgkin's disease (HD) survivors at a median of 14.3 years (range, 5.9 to 27.5 years) after diagnosis because they may be at increased risk for cardiovascular abnormalities...
  61. ncbi request reprint Improved outcomes of pediatric dilated cardiomyopathy with utilization of heart transplantation
    Anna E Tsirka
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
    J Am Coll Cardiol 44:391-7. 2004
    ..We studied the outcomes of pediatric patients diagnosed with dilated cardiomyopathy (DCM) and their relation to epidemiologic and echocardiographic variables at the time of presentation...

Research Grants35

  1. HAART Associated Cardiotoxicity in HIV-Infected Children
    Steven Lipshultz; Fiscal Year: 2006
    ..The findings will help determine the need for cardiovascular follow-up, prevention and therapeutic trials. ..
  2. CARDIAC RISK FACTORS IN PEDIATRIC CANCER SURVIVORS
    Steven Lipshultz; Fiscal Year: 2001
    ..If the hypotheses are true, this should enable more rational recommendations for preventive cardiology in long-term survivors to be made and to standardize care and management for this population. ..
  3. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2000
    ..abstract_text> ..
  4. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2007
    ..These studies will dramatically increase our understanding of pediatric cardiomyopathy, suggest new areas of research and improved patient management. ..
  5. CARDIAC RISK FACTORS IN PEDIATRIC CANCER SURVIVORS
    Steven Lipshultz; Fiscal Year: 2000
    ..If the hypotheses are true, this should enable more rational recommendations for preventive cardiology in long-term survivors to be made and to standardize care and management for this population. ..
  6. HAART Associated Cardiotoxicity in HIV-Infected Children
    Steven Lipshultz; Fiscal Year: 2004
    ..The findings will help determine the need for cardiovascular follow-up, prevention and therapeutic trials. ..
  7. Cardiovascular Status of HAART-Exposed Infants/Children
    Steven Lipshultz; Fiscal Year: 2002
    ..This study will determine the cardiovascular effects of HAART in seroreverters and the need for future cardiovascular follow-up and cardiovascular preventive and therapeutic trials in this rapidly expanding population. ..
  8. Cardiovascular Status of HAART-Exposed Infants/Children
    Steven Lipshultz; Fiscal Year: 2004
    ..This study will determine the cardiovascular effects of HAART in seroreverters and the need for future cardiovascular follow-up and cardiovascular preventive and therapeutic trials in this rapidly expanding population. ..
  9. Primary Cardiomyopathies in Children: Research Directions & Strategies
    Steven Lipshultz; Fiscal Year: 2007
    ..It is anticipated that this exchange of knowledge will identify future research directions and new approaches and technologies that will lead to a better understanding of this disease and improved treatment and prevention strategies. ..
  10. HAART Associated Cardiotoxicity in HIV-Infected Children
    Steven Lipshultz; Fiscal Year: 2005
    ..The findings will help determine the need for cardiovascular follow-up, prevention and therapeutic trials. ..
  11. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 1999
    ..The registry should lead to definitive understanding of the pathogenesis of these disorders and offer the hope to have a major clinical impact on the clinical practice of medicine in this area. ..
  12. Cardiovascular Status of HAART-Exposed Infants/Children
    Steven Lipshultz; Fiscal Year: 2003
    ..This study will determine the cardiovascular effects of HAART in seroreverters and the need for future cardiovascular follow-up and cardiovascular preventive and therapeutic trials in this rapidly expanding population. ..
  13. Genetic Mechanisms of Anthracycline Cardiotoxicity in Pediatric Cancer Survivors
    Steven Lipshultz; Fiscal Year: 2007
    ..If the HFE mutations are related to increased cardiotoxicity of anthracyclines. This study will elucidate the molecular mechanisms of anthracycline cardiotoxicity in pediatric ALL cancer survivors. ..
  14. HAART Associated Cardiotoxicity in HIV-Infected Children
    Steven Lipshultz; Fiscal Year: 2007
    ..The findings will help determine the need for cardiovascular follow-up, prevention and therapeutic trials. ..
  15. Cardiovascular Status of HAART-Exposed Infants/Children
    Steven Lipshultz; Fiscal Year: 2003
    ..This study will determine the cardiovascular effects of HAART in seroreverters and the need for future cardiovascular follow-up and cardiovascular preventive and therapeutic trials in this rapidly expanding population. ..
  16. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2001
    ..abstract_text> ..
  17. CARDIAC RISK FACTORS IN PEDIATRIC CANCER SURVIVORS
    Steven Lipshultz; Fiscal Year: 1999
    ..If the hypotheses are true, this should enable more rational recommendations for preventive cardiology in long-term survivors to be made and to standardize care and management for this population. ..
  18. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2000
    ..The registry should lead to definitive understanding of the pathogenesis of these disorders and offer the hope to have a major clinical impact on the clinical practice of medicine in this area. ..
  19. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2003
    ..abstract_text> ..
  20. Cardiovascular Status of HAART-Exposed Infants/Children
    Steven Lipshultz; Fiscal Year: 2006
    ..This study will determine the cardiovascular effects of HAART in seroreverters and the need for future cardiovascular follow-up and cardiovascular preventive and therapeutic trials in this rapidly expanding population. ..
  21. CARDIAC RISK FACTORS IN PEDIATRIC CANCER SURVIVORS
    Steven Lipshultz; Fiscal Year: 2002
    ..If the hypotheses are true, this should enable more rational recommendations for preventive cardiology in long-term survivors to be made and to standardize care and management for this population. ..
  22. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2006
    ..These studies will dramatically increase our understanding of pediatric cardiomyopathy, suggest new areas of research and improved patient management. ..
  23. CARDIAC RISK FACTORS IN PEDIATRIC CANCER SURVIVORS
    Steven Lipshultz; Fiscal Year: 2002
    ..If the hypotheses are true, this should enable more rational recommendations for preventive cardiology in long-term survivors to be made and to standardize care and management for this population. ..
  24. Cardiovascular Status of HAART-Exposed Infants/Children
    Steven Lipshultz; Fiscal Year: 2005
    ..This study will determine the cardiovascular effects of HAART in seroreverters and the need for future cardiovascular follow-up and cardiovascular preventive and therapeutic trials in this rapidly expanding population. ..
  25. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2002
    ..abstract_text> ..
  26. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2005
    ..These studies will dramatically increase our understanding of pediatric cardiomyopathy, suggest new areas of research and improved patient management. ..
  27. PEDIATRIC CARDIOMYOPATHY REGISTRY
    Steven Lipshultz; Fiscal Year: 2009
    ..These studies will dramatically increase our understanding of pediatric cardiomyopathy, suggest new areas of research and improved patient management. ..
  28. Genetic Mechanisms of Anthracycline Cardiotoxicity in Pediatric Cancer Survivors
    Steven Lipshultz; Fiscal Year: 2009
    ..If the HFE mutations are related to increased cardiotoxicity of anthracyclines. This study will elucidate the molecular mechanisms of anthracycline cardiotoxicity in pediatric ALL cancer survivors. ..