Darren R Linkin

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Effect of communication errors during calls to an antimicrobial stewardship program
    Darren R Linkin
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Infect Control Hosp Epidemiol 28:1374-81. 2007
  2. ncbi request reprint Applicability of Healthcare Failure Mode and Effects Analysis to healthcare epidemiology: evaluation of the sterilization and use of surgical instruments
    Darren R Linkin
    Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, USA
    Clin Infect Dis 41:1014-9. 2005
  3. pmc Inaccurate communications in telephone calls to an antimicrobial stewardship program
    Darren R Linkin
    Department of Medicine, Division of Infectious Diseases, University of Pennsylvania, Philadelphia, PA 19104, USA
    Infect Control Hosp Epidemiol 27:688-94. 2006
  4. pmc The effect of a hospital-wide urine culture screening intervention on the incidence of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella species
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    Infect Control Hosp Epidemiol 34:1160-6. 2013
  5. pmc Evaluation of antimicrobial therapy orders circumventing an antimicrobial stewardship program: investigating the strategy of "stealth dosing"
    Lori Ann LaRosa
    Department of Pharmacy, University of Pennsylvania, Philadelphia, PA, USA
    Infect Control Hosp Epidemiol 28:551-6. 2007
  6. pmc Role of matching in case-control studies of antimicrobial resistance
    Elizabeth Cerceo
    Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 30:479-83. 2009
  7. pmc Stockpiling drugs for an avian influenza outbreak: examining the surge in oseltamivir prescriptions during heightened media coverage of the potential for a worldwide pandemic
    Leanne B Gasink
    Divisions of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Infect Control Hosp Epidemiol 30:370-6. 2009
  8. pmc Public reporting of hospital-acquired infections is not associated with improved processes or outcomes
    Darren R Linkin
    Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 34:844-6. 2013
  9. pmc Risk factors for gastrointestinal tract colonization with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella species in hospitalized patients
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 33:1242-5. 2012
  10. ncbi request reprint Use of different thresholds of prior antimicrobial use in defining exposure: impact on the association between antimicrobial use and antimicrobial resistance
    Emily P Hyle
    Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Infect 55:414-8. 2007

Detail Information

Publications21

  1. pmc Effect of communication errors during calls to an antimicrobial stewardship program
    Darren R Linkin
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Infect Control Hosp Epidemiol 28:1374-81. 2007
    ....
  2. ncbi request reprint Applicability of Healthcare Failure Mode and Effects Analysis to healthcare epidemiology: evaluation of the sterilization and use of surgical instruments
    Darren R Linkin
    Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, USA
    Clin Infect Dis 41:1014-9. 2005
    ..The HFMEA methodology facilitated the detection of previously unrecognized system errors, demonstrating its potential utility in addressing healthcare epidemiology-related adverse events...
  3. pmc Inaccurate communications in telephone calls to an antimicrobial stewardship program
    Darren R Linkin
    Department of Medicine, Division of Infectious Diseases, University of Pennsylvania, Philadelphia, PA 19104, USA
    Infect Control Hosp Epidemiol 27:688-94. 2006
    ....
  4. pmc The effect of a hospital-wide urine culture screening intervention on the incidence of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella species
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
    Infect Control Hosp Epidemiol 34:1160-6. 2013
    ..The objective of this study was to evaluate the impact of a urine culture screening strategy on the incidence of ESBL-EK...
  5. pmc Evaluation of antimicrobial therapy orders circumventing an antimicrobial stewardship program: investigating the strategy of "stealth dosing"
    Lori Ann LaRosa
    Department of Pharmacy, University of Pennsylvania, Philadelphia, PA, USA
    Infect Control Hosp Epidemiol 28:551-6. 2007
    ..We evaluated whether prescribers wait until after the prior-approval period to order restricted antimicrobial therapy that is in conflict with guidelines or unnecessary...
  6. pmc Role of matching in case-control studies of antimicrobial resistance
    Elizabeth Cerceo
    Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 30:479-83. 2009
    ..Analysis that accounted for matching was performed in only 52% of the case-control studies...
  7. pmc Stockpiling drugs for an avian influenza outbreak: examining the surge in oseltamivir prescriptions during heightened media coverage of the potential for a worldwide pandemic
    Leanne B Gasink
    Divisions of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Infect Control Hosp Epidemiol 30:370-6. 2009
    ....
  8. pmc Public reporting of hospital-acquired infections is not associated with improved processes or outcomes
    Darren R Linkin
    Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 34:844-6. 2013
    ..We conducted a survey of infection control professionals and found that state-legislated public reporting of HAIs is not associated with perceived improvements in infection prevention program process measures or HAI rates. ..
  9. pmc Risk factors for gastrointestinal tract colonization with extended-spectrum β-lactamase (ESBL)-producing Escherichia coli and Klebsiella species in hospitalized patients
    Jennifer H Han
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 33:1242-5. 2012
    ..The prevalence of colonization with ESBL-EK was 2.6%. Colonization was associated with cirrhosis, longer duration of hospital stay prior to surveillance, and prior exposure to clindamycin or meropenem...
  10. ncbi request reprint Use of different thresholds of prior antimicrobial use in defining exposure: impact on the association between antimicrobial use and antimicrobial resistance
    Emily P Hyle
    Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Infect 55:414-8. 2007
    ..We conducted the current study to determine the impact of varying the minimum threshold of prior antimicrobial use to define exposure status in studies of antimicrobial resistance...
  11. doi request reprint Clinical and microbiological outcomes of serious infections with multidrug-resistant gram-negative organisms treated with tigecycline
    Kara B Anthony
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Clin Infect Dis 46:567-70. 2008
    ..Observed evolution of resistance during therapy raises concern about routine use of tigecycline in treatment of such infections when other therapies are available...
  12. pmc Effect of accessibility of influenza vaccination on the rate of childcare staff vaccination
    Ingi Lee
    Division of Infectious Diseases, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Infect Control Hosp Epidemiol 29:465-7. 2008
    ..Staff vaccination prevalence was higher in each intervention season compared to the prior, nonintervention season. No baseline characteristics were associated with receipt of vaccination...
  13. ncbi request reprint Fluoroquinolone-resistant Escherichia coli in the long-term care setting
    Alana E Cohen
    Columbia University, Department of Medicine, New York, NY, USA
    Am J Med 119:958-63. 2006
    ..Prior studies have found fluoroquinolone exposure to be a risk factor for infection with fluoroquinolone-resistant gram-negative rods in the acute care setting. However, risk factors may be different in the long-term care setting...
  14. pmc Effectiveness of an information technology intervention to improve prophylactic antibacterial use in the postoperative period
    Kevin Haynes
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, and Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Am Med Inform Assoc 18:164-8. 2011
    ..Electronic order sets have shown promise as a means of integrating guideline information with electronic order entry systems and facilitating safer, more effective care...
  15. pmc Variations in identification of healthcare-associated infections
    Sara C Keller
    Center for Healthcare Improvement and Patient Safety, Division of Infectious Diseases, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19103, USA
    Infect Control Hosp Epidemiol 34:678-86. 2013
    ..Our primary objective was to characterize variations in these interpretations using clinical vignettes. We also describe predictors of variation in responses...
  16. pmc Effectiveness of interventions in reducing antibiotic use for upper respiratory infections in ambulatory care practices
    Christopher Vinnard
    Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA
    Popul Health Manag 16:22-7. 2013
    ..Organizations that seek to reduce inappropriate use of antibiotics should use proven approaches, even when they are more expensive...
  17. ncbi request reprint Identification of optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection: potential role of a Combination Antibiogram
    Mari Mizuta
    Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Infect Control Hosp Epidemiol 27:413-5. 2006
    ..Drug combinations with the broadest coverage were consistently composed of an aminoglycoside and a beta-lactam...
  18. ncbi request reprint Improving disease reporting by clinicians: the effect of an internet-based intervention
    Lawrence D Ward
    Section of General Internal Medicine, Department of Medicine, Temple University, Philadelphia, Pennsylvania 19140, USA
    J Public Health Manag Pract 14:56-61. 2008
    ..We sought to determine whether an intervention utilizing electronic media increases public health reporting by clinicians...
  19. pmc Isoniazid Toxicity among an Older Veteran Population: A Retrospective Cohort Study
    Christopher Vinnard
    Division of Infectious Diseases and HIV Medicine, College of Medicine, Drexel University, 245 N 15th Street MS 461, New College Building 6314, Philadelphia, PA 19102, USA
    Tuberc Res Treat 2013:549473. 2013
    ..Alternative LTBI treatment approaches should be further examined in the veteran population...
  20. ncbi request reprint Risk factors for extended-spectrum beta-lactamase-producing Enterobacteriaceae in a neonatal intensive care unit
    Darren R Linkin
    Department of Medicine, Center for Education and Research on Therapeutics, University of Pennsylvania, Philadelphia 19104, USA
    Infect Control Hosp Epidemiol 25:781-3. 2004
    ..We also reviewed the existing medical literature regarding the clinical epidemiology of ESBLs in NICUs ...
  21. ncbi request reprint Ciprofloxacin versus tobramycin for neutropenic fevers
    Darren R Linkin
    Ann Intern Med 138:435-6; author reply 436. 2003

Research Grants4

  1. Risk of Infectious Complications in Nosocomial Pneumonia
    Darren Linkin; Fiscal Year: 2007
    ..abstract_text> ..
  2. Diversity of Antimicrobial Use and Emergence of Resistance in Pseudomonas
    Darren Linkin; Fiscal Year: 2007
    ..The results of our study will be generalizable to inpatients in tertiary acute care centers everywhere. ..