Research Topics
| Darren R LinkinSummaryAffiliation: University of Pennsylvania Country: USA Publications
Research Grants
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Detail Information
Publications
Effect of communication errors during calls to an antimicrobial stewardship programDarren R Linkin
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Infect Control Hosp Epidemiol 28:1374-81. 2007....- Applicability of Healthcare Failure Mode and Effects Analysis to healthcare epidemiology: evaluation of the sterilization and use of surgical instrumentsDarren R Linkin
Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, USA
Clin Infect Dis 41:1014-9. 2005..The HFMEA methodology facilitated the detection of previously unrecognized system errors, demonstrating its potential utility in addressing healthcare epidemiology-related adverse events... 
Inaccurate communications in telephone calls to an antimicrobial stewardship programDarren R Linkin
Department of Medicine, Division of Infectious Diseases, University of Pennsylvania, Philadelphia, PA 19104, USA
Infect Control Hosp Epidemiol 27:688-94. 2006....- Stockpiling drugs for an avian influenza outbreak: examining the surge in oseltamivir prescriptions during heightened media coverage of the potential for a worldwide pandemicLeanne B Gasink
Divisions of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Infect Control Hosp Epidemiol 30:370-6. 2009.... - Role of matching in case-control studies of antimicrobial resistanceElizabeth Cerceo
Division of Infectious Diseases, Department of Medicine, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Infect Control Hosp Epidemiol 30:479-83. 2009..Analysis that accounted for matching was performed in only 52% of the case-control studies... - Evaluation of antimicrobial therapy orders circumventing an antimicrobial stewardship program: investigating the strategy of "stealth dosing"Lori Ann LaRosa
Department of Pharmacy, University of Pennsylvania, Philadelphia, PA, USA
Infect Control Hosp Epidemiol 28:551-6. 2007..We evaluated whether prescribers wait until after the prior-approval period to order restricted antimicrobial therapy that is in conflict with guidelines or unnecessary... - Use of different thresholds of prior antimicrobial use in defining exposure: impact on the association between antimicrobial use and antimicrobial resistanceEmily P Hyle
Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Infect 55:414-8. 2007..We conducted the current study to determine the impact of varying the minimum threshold of prior antimicrobial use to define exposure status in studies of antimicrobial resistance... 
Clinical and microbiological outcomes of serious infections with multidrug-resistant gram-negative organisms treated with tigecyclineKara B Anthony
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
Clin Infect Dis 46:567-70. 2008..Observed evolution of resistance during therapy raises concern about routine use of tigecycline in treatment of such infections when other therapies are available...- Risk Factors for Gastrointestinal Tract Colonization with Extended-Spectrum β-Lactamase (ESBL)-Producing Escherichia coli and Klebsiella Species in Hospitalized PatientsJennifer H Han
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Infect Control Hosp Epidemiol 33:1242-5. 2012..The prevalence of colonization with ESBL-EK was 2.6%. Colonization was associated with cirrhosis, longer duration of hospital stay prior to surveillance, and prior exposure to clindamycin or meropenem... - Effect of accessibility of influenza vaccination on the rate of childcare staff vaccinationIngi Lee
Division of Infectious Diseases, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
Infect Control Hosp Epidemiol 29:465-7. 2008..Staff vaccination prevalence was higher in each intervention season compared to the prior, nonintervention season. No baseline characteristics were associated with receipt of vaccination... - Effectiveness of an information technology intervention to improve prophylactic antibacterial use in the postoperative periodKevin Haynes
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, and Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Am Med Inform Assoc 18:164-8. 2011..Electronic order sets have shown promise as a means of integrating guideline information with electronic order entry systems and facilitating safer, more effective care... - Fluoroquinolone-resistant Escherichia coli in the long-term care settingAlana E Cohen
Columbia University, Department of Medicine, New York, NY, USA
Am J Med 119:958-63. 2006..Further studies are needed to examine the effect of interventions to decrease fluoroquinolone-resistant infections in the long-term care setting, including studying the effect of decreasing fluoroquinolone use... - Identification of optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection: potential role of a Combination AntibiogramMari Mizuta
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, 423 Guardian Drive, Philadelphia, PA 19104, USA
Infect Control Hosp Epidemiol 27:413-5. 2006..Drug combinations with the broadest coverage were consistently composed of an aminoglycoside and a beta-lactam... - Improving disease reporting by clinicians: the effect of an internet-based interventionLawrence D Ward
Section of General Internal Medicine, Department of Medicine, Temple University, Philadelphia, Pennsylvania 19140, USA
J Public Health Manag Pract 14:56-61. 2008..We sought to determine whether an intervention utilizing electronic media increases public health reporting by clinicians... - Effectiveness of interventions in reducing antibiotic use for upper respiratory infections in ambulatory care practicesChristopher Vinnard
Division of Infectious Diseases and HIV Medicine, Department of Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA
Popul Health Manag 16:22-7. 2013..Organizations that seek to reduce inappropriate use of antibiotics should use proven approaches, even when they are more expensive... - Isoniazid Toxicity among an Older Veteran Population: A Retrospective Cohort StudyChristopher Vinnard
Division of Infectious Diseases and HIV Medicine, College of Medicine, Drexel University, 245 N 15th Street MS 461, New College Building 6314, Philadelphia, PA 19102, USA
Tuberc Res Treat 2013:549473. 2013..Alternative LTBI treatment approaches should be further examined in the veteran population... - Risk factors for extended-spectrum beta-lactamase-producing Enterobacteriaceae in a neonatal intensive care unitDarren R Linkin
Department of Medicine, Center for Education and Research on Therapeutics, University of Pennsylvania, Philadelphia 19104, USA
Infect Control Hosp Epidemiol 25:781-3. 2004..We also reviewed the existing medical literature regarding the clinical epidemiology of ESBLs in NICUs ... - Ciprofloxacin versus tobramycin for neutropenic feversDarren R Linkin
Ann Intern Med 138:435-6; author reply 436. 2003
Research Grants
- Risk of Infectious Complications in Nosocomial PneumoniaDarren Linkin; Fiscal Year: 2007..abstract_text> ..
- Diversity of Antimicrobial Use and Emergence of Resistance in PseudomonasDarren Linkin; Fiscal Year: 2007..The results of our study will be generalizable to inpatients in tertiary acute care centers everywhere. ..