Alicia S Linford
Affiliation: University of Virginia
- Crystal structure and putative substrate identification for the Entamoeba histolytica low molecular weight tyrosine phosphataseAlicia S Linford
Department of Biochemistry and Molecular Genetics, University of Virginia Health System, Charlottesville, VA 22908, USA Electronic address
Mol Biochem Parasitol 193:33-44. 2014..This is the first biochemical study of a small tyrosine phosphatase in Entamoeba, and sets the stage for understanding its role in amebic biology and pathogenesis. ..
- Short hairpin RNA-mediated knockdown of protein expression in Entamoeba histolyticaAlicia S Linford
Department of Microbiology, University of Virginia, Charlottesville, Virginia, USA
BMC Microbiol 9:38. 2009..We chose to test the use of RNA interference to knock down gene expression in Entamoeba histolytica...
- Phospholipid-binding protein EhC2A mediates calcium-dependent translocation of transcription factor URE3-BP to the plasma membrane of Entamoeba histolyticaHeriberto Moreno
Division of Infectious Diseases and International Health, University of Virginia, P O Box 801340, Charlottesville, VA 22908, USA
Eukaryot Cell 9:695-704. 2010..Based on these results, we propose a model for EhC2A-mediated regulation of the transcriptional activities of URE3-BP via Ca(2+)-dependent anchoring of the transcription factor to the amebic plasma membrane...
- Entamoeba histolytica phagocytosis of human erythrocytes involves PATMK, a member of the transmembrane kinase familyDouglas R Boettner
Department of Microbiology, University of Virginia, Charlottesville, Virginia, United States of America
PLoS Pathog 4:e8. 2008..In conclusion, PATMK was identified as a member of the TMK family that participates in erythrophagocytosis and is uniquely required for intestinal infection...