Matthew Dean Linden

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi request reprint Decreased concentration of antithrombin after preoperative therapeutic heparin does not cause heparin resistance during cardiopulmonary bypass
    Matthew D Linden
    Department of Pathology, The University of Western Australia, Nedlands, Australia
    J Cardiothorac Vasc Anesth 18:131-5. 2004
  2. ncbi request reprint The hemostatic defect of cardiopulmonary bypass
    Matthew Dean Linden
    Center for Platelet Function Studies, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    J Thromb Thrombolysis 16:129-47. 2003
  3. ncbi request reprint Acute normovolemic hemodilution does not reduce antithrombin concentration for cardiac surgery
    Matthew Dean Linden
    Department of Pathology, University of Western Australia, Nedlands, Western Australia, Australia
    J Thromb Thrombolysis 17:173-6. 2004
  4. ncbi request reprint Application of flow cytometry to platelet disorders
    Matthew D Linden
    Center for Platelet Function Studies, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Semin Thromb Hemost 30:501-11. 2004
  5. ncbi request reprint Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance
    Andrew L Frelinger
    Center for Platelet Function Studies, Department of Pediatrics, UMass Memorial Medical Center, 55 Lake Ave N, Worcester, Massachusetts 01655, USA
    Circulation 113:2888-96. 2006
  6. ncbi request reprint Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization
    Mark I Furman
    Center for Platelet Function Studies, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Am Coll Cardiol 43:2319-25. 2004
  7. ncbi request reprint Platelet activation in cystic fibrosis
    Brian P O'Sullivan
    Department of Pediatrics, UMass Memorial Health Care and University of Massachusetts Medical School, Worcester, MA 01655, USA
    Blood 105:4635-41. 2005
  8. pmc Effect of adenosine A2 receptor stimulation on platelet activation-aggregation: differences between canine and human models
    Matthew D Linden
    Center for Platelet Function Studies, University of Massachusetts Medical School, Worcester MA 01655, United States
    Thromb Res 121:689-98. 2008
  9. ncbi request reprint The active metabolite of prasugrel inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: Influence of other blood cells, calcium, and aspirin
    Andrew L Frelinger
    Center for Platelet Function Studies, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Thromb Haemost 98:192-200. 2007

Detail Information

Publications9

  1. ncbi request reprint Decreased concentration of antithrombin after preoperative therapeutic heparin does not cause heparin resistance during cardiopulmonary bypass
    Matthew D Linden
    Department of Pathology, The University of Western Australia, Nedlands, Australia
    J Cardiothorac Vasc Anesth 18:131-5. 2004
    ..To determine if preoperative heparin therapy causes an increase in the incidence of intraoperative heparin resistance by reducing the concentration of antithrombin in plasma...
  2. ncbi request reprint The hemostatic defect of cardiopulmonary bypass
    Matthew Dean Linden
    Center for Platelet Function Studies, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    J Thromb Thrombolysis 16:129-47. 2003
    ..Research into many strategies for minimizing the hemostatic defect of cardiopulmonary bypass is incomplete, with safety and efficacy the subjects of intensive investigation...
  3. ncbi request reprint Acute normovolemic hemodilution does not reduce antithrombin concentration for cardiac surgery
    Matthew Dean Linden
    Department of Pathology, University of Western Australia, Nedlands, Western Australia, Australia
    J Thromb Thrombolysis 17:173-6. 2004
    ..The aim of this study was to determine if antithrombin concentrations are reduced in patients who undergo one unit of ANH during cardiac surgery...
  4. ncbi request reprint Application of flow cytometry to platelet disorders
    Matthew D Linden
    Center for Platelet Function Studies, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Semin Thromb Hemost 30:501-11. 2004
    ..Accordingly, this review summarizes the key technical and methodologic components of flow cytometric analysis of platelets, as well as specific examples of its application to diagnosis and patient care...
  5. ncbi request reprint Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance
    Andrew L Frelinger
    Center for Platelet Function Studies, Department of Pediatrics, UMass Memorial Medical Center, 55 Lake Ave N, Worcester, Massachusetts 01655, USA
    Circulation 113:2888-96. 2006
    ..Thrombotic events still occur in aspirin-treated patients with coronary artery disease...
  6. ncbi request reprint Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization
    Mark I Furman
    Center for Platelet Function Studies, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Am Coll Cardiol 43:2319-25. 2004
    ....
  7. ncbi request reprint Platelet activation in cystic fibrosis
    Brian P O'Sullivan
    Department of Pediatrics, UMass Memorial Health Care and University of Massachusetts Medical School, Worcester, MA 01655, USA
    Blood 105:4635-41. 2005
    ..Our findings may account, at least in part, for the beneficial effects of ibuprofen in CF...
  8. pmc Effect of adenosine A2 receptor stimulation on platelet activation-aggregation: differences between canine and human models
    Matthew D Linden
    Center for Platelet Function Studies, University of Massachusetts Medical School, Worcester MA 01655, United States
    Thromb Res 121:689-98. 2008
    ....
  9. ncbi request reprint The active metabolite of prasugrel inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: Influence of other blood cells, calcium, and aspirin
    Andrew L Frelinger
    Center for Platelet Function Studies, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Thromb Haemost 98:192-200. 2007
    ..This inhibition is enhanced in the presence other blood cells and calcium, but not aspirin...