Jack J Lin

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Striatal hypertrophy and its cognitive effects in new-onset benign epilepsy with centrotemporal spikes
    Jack J Lin
    Department of Neurology, University of California, Irvine, California 92697, USA
    Epilepsia 53:677-85. 2012
  2. pmc Three-dimensional preoperative maps of hippocampal atrophy predict surgical outcomes in temporal lobe epilepsy
    J J Lin
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Neurology 65:1094-7. 2005
  3. ncbi request reprint Reduced neocortical thickness and complexity mapped in mesial temporal lobe epilepsy with hippocampal sclerosis
    Jack J Lin
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Cereb Cortex 17:2007-18. 2007
  4. doi request reprint Vulnerability of the frontal-temporal connections in temporal lobe epilepsy
    Jack J Lin
    Department of Neurology, University of California, Irvine, CA, USA
    Epilepsy Res 82:162-70. 2008
  5. pmc Three-dimensional surface maps link local atrophy and fast ripples in human epileptic hippocampus
    Jennifer A Ogren
    Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 7169, USA
    Ann Neurol 66:783-91. 2009
  6. pmc Altered white matter integrity in temporal lobe epilepsy: association with cognitive and clinical profiles
    Jeffrey D Riley
    Department of Neurology, University of California, Irvine, CA 92868, USA
    Epilepsia 51:536-45. 2010
  7. pmc Three-dimensional hippocampal atrophy maps distinguish two common temporal lobe seizure-onset patterns
    Jennifer A Ogren
    Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 7169, USA
    Epilepsia 50:1361-70. 2009
  8. pmc Ventricular enlargement in new-onset pediatric epilepsies
    Daren C Jackson
    Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 0001, USA
    Epilepsia 52:2225-32. 2011
  9. pmc Caudate atrophy and impaired frontostriatal connections are linked to executive dysfunction in temporal lobe epilepsy
    Jeffrey D Riley
    Department of Neurology, University of California, Irvine, Irvine, CA, USA
    Epilepsy Behav 21:80-7. 2011
  10. doi request reprint Neurobehavioral comorbidities of pediatric epilepsies are linked to thalamic structural abnormalities
    Jack J Lin
    Department of Neurology, University of California Irvine, Irvine, California, U S A
    Epilepsia 54:2116-24. 2013

Collaborators

Detail Information

Publications14

  1. pmc Striatal hypertrophy and its cognitive effects in new-onset benign epilepsy with centrotemporal spikes
    Jack J Lin
    Department of Neurology, University of California, Irvine, California 92697, USA
    Epilepsia 53:677-85. 2012
    ..Given the motor manifestations of seizures in BECTS, we hypothesize that anatomic networks in BECTS involve a distributed corticostriatal circuit...
  2. pmc Three-dimensional preoperative maps of hippocampal atrophy predict surgical outcomes in temporal lobe epilepsy
    J J Lin
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Neurology 65:1094-7. 2005
    ..These atrophic regions may indicate areas of increased epileptogenicity, contributing to poorer surgical outcomes...
  3. ncbi request reprint Reduced neocortical thickness and complexity mapped in mesial temporal lobe epilepsy with hippocampal sclerosis
    Jack J Lin
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Cereb Cortex 17:2007-18. 2007
    ..The pervasive extrahippocampal structural deficits may result from chronic seizure propagation or may reflect other causes such as initial precipitating factors leading to MTLE...
  4. doi request reprint Vulnerability of the frontal-temporal connections in temporal lobe epilepsy
    Jack J Lin
    Department of Neurology, University of California, Irvine, CA, USA
    Epilepsy Res 82:162-70. 2008
    ..We therefore investigated the integrity of two major frontal-temporal white matter association tracts, uncinate fasciculus (UF) and arcuate fasciculus (AF), and their clinical correlates...
  5. pmc Three-dimensional surface maps link local atrophy and fast ripples in human epileptic hippocampus
    Jennifer A Ogren
    Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 7169, USA
    Ann Neurol 66:783-91. 2009
    ..It is hypothesized that morphological changes associated with hippocampal atrophy (HA) contribute to the generation of FR, yet there is limited evidence that hippocampal FR-generating sites correspond with local areas of atrophy...
  6. pmc Altered white matter integrity in temporal lobe epilepsy: association with cognitive and clinical profiles
    Jeffrey D Riley
    Department of Neurology, University of California, Irvine, CA 92868, USA
    Epilepsia 51:536-45. 2010
    ..However, limited data exist regarding the extent of white matter tract abnormalities, cognitive effects of these abnormalities, and relationship to clinical factors. The current study examined these issues in subjects with chronic TLE...
  7. pmc Three-dimensional hippocampal atrophy maps distinguish two common temporal lobe seizure-onset patterns
    Jennifer A Ogren
    Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 7169, USA
    Epilepsia 50:1361-70. 2009
    ..We used three-dimensional (3D) hippocampal mapping to quantify HA and determine whether each onset group exhibited a unique distribution of atrophy consistent with the functional differences that distinguish the two onset morphologies...
  8. pmc Ventricular enlargement in new-onset pediatric epilepsies
    Daren C Jackson
    Department of Neurology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 0001, USA
    Epilepsia 52:2225-32. 2011
    ..To examine baseline and prospective (2-year) changes in third, fourth, and lateral ventricle volumes in children with new-onset idiopathic epilepsies and controls (age 8-18 years)...
  9. pmc Caudate atrophy and impaired frontostriatal connections are linked to executive dysfunction in temporal lobe epilepsy
    Jeffrey D Riley
    Department of Neurology, University of California, Irvine, Irvine, CA, USA
    Epilepsy Behav 21:80-7. 2011
    ..The results suggest that atrophy in the dorsal head of the caudate might disrupt frontostriatal networks that are critical for executive functioning in TLE...
  10. doi request reprint Neurobehavioral comorbidities of pediatric epilepsies are linked to thalamic structural abnormalities
    Jack J Lin
    Department of Neurology, University of California Irvine, Irvine, California, U S A
    Epilepsia 54:2116-24. 2013
    ..We examined the shared versus unique structural-functional relationships of these volumes with behavior problems, intelligence, language, peer interaction, and epilepsy variables in these two epilepsy syndromes...
  11. pmc The emerging architecture of neuropsychological impairment in epilepsy
    Bruce P Hermann
    Department of Neurology, University of Wisconsin School of Medicine and Public Health, 600 North Highland Avenue, Madison, WI 53792, USA
    Neurol Clin 27:881-907. 2009
    ....
  12. pmc The neurobiology of cognitive disorders in temporal lobe epilepsy
    Brian Bell
    Department of Neurology, University of Wisconsin School of Medicine and Public Health, 600 North Highland Avenue, Madison, WI 53792, USA
    Nat Rev Neurol 7:154-64. 2011
    ..Clarifying the origin of these cognitive and anatomical abnormalities, their progression over time and, most importantly, methods for protecting cognitive and brain health in epilepsy, present a challenge to neurologists...
  13. pmc Uncovering the neurobehavioural comorbidities of epilepsy over the lifespan
    Jack J Lin
    Department of Neurology, University of California at Irvine, Irvine, CA, USA
    Lancet 380:1180-92. 2012
    ....
  14. pmc MRI analysis in temporal lobe epilepsy: cortical thinning and white matter disruptions are related to side of seizure onset
    Nobuko Kemmotsu
    Department of Psychiatry, University of California, San Diego, California, USA
    Epilepsia 52:2257-66. 2011
    ..This study investigated the relationship between cortical thinning, white matter compromise, epilepsy variables, and the side of seizure onset, in patients with TLE...