Daniel W Lin

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer
    Elahe A Mostaghel
    Fred Hutchinson Cancer Research Center, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    Cancer Res 67:5033-41. 2007
  2. pmc Urinary TMPRSS2:ERG and PCA3 in an active surveillance cohort: results from a baseline analysis in the Canary Prostate Active Surveillance Study
    Daniel W Lin
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Clin Cancer Res 19:2442-50. 2013
  3. ncbi request reprint Intermittent androgen deprivation: clinical experience and practical applications
    Jonathan L Wright
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Urol Clin North Am 33:167-79, vi. 2006
  4. doi request reprint Beyond PSA: utility of novel tumor markers in the setting of elevated PSA
    Daniel W Lin
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Urol Oncol 27:315-21. 2009
  5. ncbi request reprint Low-fat, low-glycemic load diet and gene expression in human prostate epithelium: a feasibility study of using cDNA microarrays to assess the response to dietary intervention in target tissues
    Daniel W Lin
    Division of Public Health, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Cancer Epidemiol Biomarkers Prev 16:2150-4. 2007
  6. ncbi request reprint Influence of surgical manipulation on prostate gene expression: implications for molecular correlates of treatment effects and disease prognosis
    Daniel W Lin
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Clin Oncol 24:3763-70. 2006
  7. ncbi request reprint The role of cyclooxygenase-2 inhibition for the prevention and treatment of prostate carcinoma
    Daniel W Lin
    Department of Urology, University of Washington, Seattle, WA 98109, USA
    Clin Prostate Cancer 2:119-26. 2003
  8. pmc CYP17 polymorphisms and prostate cancer outcomes
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Prostate 70:1094-101. 2010
  9. pmc Vitamin D pathway gene variants and prostate cancer prognosis
    Sarah K Holt
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Prostate 70:1448-60. 2010
  10. ncbi request reprint Response of the insulin-like growth factor (IGF) system to IGF-IR inhibition and androgen deprivation in a neoadjuvant prostate cancer trial: effects of obesity and androgen deprivation
    James P Dean
    Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    J Clin Endocrinol Metab 98:E820-8. 2013

Detail Information

Publications81

  1. ncbi request reprint Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer
    Elahe A Mostaghel
    Fred Hutchinson Cancer Research Center, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    Cancer Res 67:5033-41. 2007
    ..Optimal clinical efficacy will require testing of novel approaches targeting complete suppression of systemic and intracrine contributions to the prostatic androgen microenvironment...
  2. pmc Urinary TMPRSS2:ERG and PCA3 in an active surveillance cohort: results from a baseline analysis in the Canary Prostate Active Surveillance Study
    Daniel W Lin
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Clin Cancer Res 19:2442-50. 2013
    ..This study examines the correlation of these biomarkers with higher cancer volume and grade determined at the time of biopsy in an active surveillance cohort...
  3. ncbi request reprint Intermittent androgen deprivation: clinical experience and practical applications
    Jonathan L Wright
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Urol Clin North Am 33:167-79, vi. 2006
    ..This article discusses the theoretical benefits and rationale of IAD and reviews the completed and on-going IAD trials. Finally, the controversies, practical applications, and future directions of IAD are addressed...
  4. doi request reprint Beyond PSA: utility of novel tumor markers in the setting of elevated PSA
    Daniel W Lin
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Urol Oncol 27:315-21. 2009
    ..This review will first highlight several characteristics of an ideal biomarker, then focus on select emerging biomarkers for the detection of prostate cancer...
  5. ncbi request reprint Low-fat, low-glycemic load diet and gene expression in human prostate epithelium: a feasibility study of using cDNA microarrays to assess the response to dietary intervention in target tissues
    Daniel W Lin
    Division of Public Health, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Cancer Epidemiol Biomarkers Prev 16:2150-4. 2007
    ..We examined the feasibility of using gene expression changes in human prostate epithelium as a measure of response to a dietary intervention...
  6. ncbi request reprint Influence of surgical manipulation on prostate gene expression: implications for molecular correlates of treatment effects and disease prognosis
    Daniel W Lin
    Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    J Clin Oncol 24:3763-70. 2006
    ..This study examines whether there are transcript alterations associated with surgical resection of the prostate gland by radical retropubic prostatectomy...
  7. ncbi request reprint The role of cyclooxygenase-2 inhibition for the prevention and treatment of prostate carcinoma
    Daniel W Lin
    Department of Urology, University of Washington, Seattle, WA 98109, USA
    Clin Prostate Cancer 2:119-26. 2003
    ..Recent progress and critical analyses in the roles of COX-2 inhibition on prostate carcinogenesis and CaP prevention will be presented...
  8. pmc CYP17 polymorphisms and prostate cancer outcomes
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Prostate 70:1094-101. 2010
    ..However, studies relating prostate cancer outcomes with CYP17 gene variants have conflicting results. In this study we analyzed Single Nucleotide Polymorphisms (SNPs) spanning the CYP17 gene for association with PCa survival...
  9. pmc Vitamin D pathway gene variants and prostate cancer prognosis
    Sarah K Holt
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Prostate 70:1448-60. 2010
    ..Increased understanding of relevant germline genetic variation with disease outcome could aid in the development of vitamin-D-based therapies...
  10. ncbi request reprint Response of the insulin-like growth factor (IGF) system to IGF-IR inhibition and androgen deprivation in a neoadjuvant prostate cancer trial: effects of obesity and androgen deprivation
    James P Dean
    Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    J Clin Endocrinol Metab 98:E820-8. 2013
    ....
  11. pmc Differential gene expression in benign prostate epithelium of men with and without prostate cancer: evidence for a prostate cancer field effect
    Michael C Risk
    Departments of Urology and Pathology, University of Washington Medical Center, 1959 NW Pacific Street, Seattle, WA 98195, USA
    Clin Cancer Res 16:5414-23. 2010
    ..We sought to determine if histologically benign prostate epithelium collected from men with prostate cancer exhibits features indicative of premalignancy or field effect...
  12. pmc Impact of male hormonal contraception on prostate androgens and androgen action in healthy men: a randomized, controlled trial
    Elahe A Mostaghel
    Division of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    J Clin Endocrinol Metab 97:2809-17. 2012
    ..Male hormonal contraception (MHC) combines hypothalamic-pituitary-gonadal axis blockade with exogenous androgen delivery to maintain extragonadal androgen end-organ effects. Concern exists that MHC may adversely impact prostate health...
  13. pmc Association of symptomatic benign prostatic hyperplasia and prostate cancer: results from the prostate cancer prevention trial
    Jeannette M Schenk
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Am J Epidemiol 173:1419-28. 2011
    ..This study provides the strongest evidence to date that BPH does not increase the risk of prostate cancer...
  14. pmc Association of hepsin gene variants with prostate cancer risk and prognosis
    Sarah K Holt
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Prostate 70:1012-9. 2010
    ..We report results from a population-based case-control genetic association study for six tagging single nucleotide polymorphisms (tagSNPs) in the HPN gene...
  15. pmc Canary Prostate Active Surveillance Study: design of a multi-institutional active surveillance cohort and biorepository
    Lisa F Newcomb
    Department of Urology, University of Washington, Seattle, Washington 98195, USA
    Urology 75:407-13. 2010
    ..The Canary Prostate Active Surveillance Study is a multicenter study and a biorepository that will discover and confirm biomarkers of aggressive disease as defined by histologic, prostate-specific antigen, or clinical criteria...
  16. ncbi request reprint Differences in survival among patients with sarcomatoid carcinoma, carcinosarcoma and urothelial carcinoma of the bladder
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    J Urol 178:2302-6; discussion 2307. 2007
    ..We investigated the survival of patients with the 2 tumor subtypes compared to survival in those with urothelial carcinoma...
  17. pmc Serum adiponectin, C-peptide and leptin and risk of symptomatic benign prostatic hyperplasia: results from the Prostate Cancer Prevention Trial
    Jeannette M Schenk
    Fred Hutchinson Cancer Research Center, Cancer Prevention Program, Seattle, Washington 98109 1024, USA
    Prostate 69:1303-11. 2009
    ..We examined whether adiponectin, leptin, and C-peptide were associated with incident, symptomatic BPH and whether these factors mediate the relationship between obesity and BPH risk...
  18. ncbi request reprint Persistent intraprostatic androgen concentrations after medical castration in healthy men
    Stephanie T Page
    University of Washington Medical Center, Division of Metabolism, Endocrinology and Nutrition, Box 357138, 1959 NE Pacific, Seattle, WA 98195
    J Clin Endocrinol Metab 91:3850-6. 2006
    ..Studies of men with prostate cancer have suggested that prostatic androgens are preserved in the setting of castration. Tissue androgens might stimulate prostate growth, producing adverse clinical consequences...
  19. pmc Androgen receptor CAG repeat length is not associated with the risk of incident symptomatic benign prostatic hyperplasia: results from the Prostate Cancer Prevention Trial
    Alan R Kristal
    Fred Hutchinson Cancer Research Center, Cancer Prevention Program, Seattle, Washington 98109 1024, USA
    Prostate 70:584-90. 2010
    ..To examine whether androgen receptor (AR) CAG repeat length was associated with the risk of incident benign prostatic hyperplasia (BPH)...
  20. pmc Biomarkers of systemic inflammation and risk of incident, symptomatic benign prostatic hyperplasia: results from the prostate cancer prevention trial
    Jeannette M Schenk
    Schenk, Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 171:571-82. 2010
    ..82; interleukin 6: OR = 1.79, 95% CI: 1.32, 2.42); these associations were only in men aged <65 years. Results suggest that systemic inflammation or lower levels of soluble receptors that bind inflammatory cytokines increase BPH risk...
  21. pmc Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: a randomized-controlled trial
    Stephanie T Page
    Division of Metabolism, Endocrinology, and Nutrition, University of Washington School of Medicine, Box 357138, 1959 NE Pacific Street, Seattle, Washington 98195, USA
    J Clin Endocrinol Metab 96:430-7. 2011
    ..Exogenous androgens raise serum DHT concentrations, but their effects on the prostate are not clear...
  22. pmc AMACR polymorphisms, dietary intake of red meat and dairy and prostate cancer risk
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Prostate 71:498-506. 2011
    ..AMACR is also a tumor tissue biomarker over-expressed in PCa. In this study, we explored the potential relationship between AMACR polymorphisms, red meat/dairy intake, and PCa risk...
  23. ncbi request reprint Prostate cancer that is within 0.1 mm of the surgical margin of a radical prostatectomy predicts greater likelihood of recurrence
    Jason P Izard
    Departments of Urology Pathology, University of Washington, Seattle, WA
    Am J Surg Pathol 38:333-8. 2014
    ..48-2.99). Cancer that is within 0.1 mm of the surgical margin of a prostatectomy is associated with an increased risk for PCa recurrence. Patients with that margin status may be reasonable candidates for adjuvant local therapy...
  24. pmc Prostate cancer mortality following active surveillance versus immediate radical prostatectomy
    Jing Xia
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, WA, USA
    Clin Cancer Res 18:5471-8. 2012
    ..The purpose of this study is to project prostate cancer mortality under active surveillance followed by radical prostatectomy versus under immediate radical prostatectomy...
  25. pmc Hospital-level variation in the quality of urologic cancer surgery
    John L Gore
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Cancer 118:987-96. 2012
    ..The authors of this report examined hospital-level variation in outcomes after inpatient urologic oncology procedures...
  26. pmc Expression of SLCO transport genes in castration-resistant prostate cancer and impact of genetic variation in SLCO1B3 and SLCO2B1 on prostate cancer outcomes
    Jonathan L Wright
    Department of Urology, University of Washington, Seattle, WA, USA
    Cancer Epidemiol Biomarkers Prev 20:619-27. 2011
    ....
  27. pmc Disseminated tumor cells in prostate cancer patients after radical prostatectomy and without evidence of disease predicts biochemical recurrence
    Todd M Morgan
    Department of Urology, University of Washington School of Medicine, 1959 NE Pacific, BB 1115, Box 356510, Seattle, WA 98195, USA
    Clin Cancer Res 15:677-83. 2009
    ..We sought to determine if epithelial-like cells identified from bone marrow in patients after radical prostatectomy, commonly called disseminated tumor cells (DTC), were associated with biochemical recurrence...
  28. pmc Clinical utility of five genetic variants for predicting prostate cancer risk and mortality
    Claudia A Salinas
    Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Prostate 69:363-72. 2009
    ..3 and a family history of the disease may predict risk of prostate cancer. The present study tests the performance of these factors in prediction models for prostate cancer risk and prostate cancer-specific mortality...
  29. doi request reprint The association between extent of lymphadenectomy and survival among patients with lymph node metastases undergoing radical cystectomy
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, WA 98195, USA
    Cancer 112:2401-8. 2008
    ..The objective of this study was to describe the association between extent of lymphadenectomy and survival in lymph node-positive patients who underwent radical cystectomy...
  30. pmc A dietary intervention to elicit rapid and complex dietary changes for studies investigating the effects of diet on tissues collected during invasive surgical procedures
    Jeannette M Schenk
    Fred Hutchinson Cancer Research Center, and Department of Epidemiology, University of Washington, Seattle, USA
    J Am Diet Assoc 109:459-63. 2009
    ..Further studies in larger and more diverse populations are needed to fully understand the potential of this novel intervention approach...
  31. doi request reprint Advanced clinical states in prostate cancer
    Heather H Cheng
    Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA 98109, USA
    Urol Clin North Am 39:561-71. 2012
    ..The authors define the current disease states and discuss implications for prognosis and treatment decisions, as well as the limitations of existing classifications and emerging discoveries...
  32. pmc Positive surgical margins at radical prostatectomy predict prostate cancer specific mortality
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington, USA
    J Urol 183:2213-8. 2010
    ..Using a large, population based national cancer registry we evaluated the risk of prostate cancer specific mortality associated with margin status...
  33. pmc Treatment and survival outcomes in young men diagnosed with prostate cancer: a Population-based Cohort Study
    Daniel W Lin
    Department of Urology, Virginia Puget Sound Health Care System, University of Washington, Northwest Prostate Cancer Specialized Program of Research Excellence, Seattle, Washington, USA
    Cancer 115:2863-71. 2009
    ..In this study, the authors examined the association between age at diagnosis and grade, stage, treatment, and survival outcomes in men who were diagnosed during the era of prostate-specific antigen testing...
  34. ncbi request reprint Cigarette smoking and prostate cancer-specific mortality following diagnosis in middle-aged men
    Zhihong Gong
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, Seattle, WA 98109 1024, USA
    Cancer Causes Control 19:25-31. 2008
    ..The aim of this study was to examine associations of smoking at the time of diagnosis with the risk of prostate cancer death in a population-based cohort of men with prostate cancer...
  35. pmc Serum steroid and sex hormone-binding globulin concentrations and the risk of incident benign prostatic hyperplasia: results from the prostate cancer prevention trial
    Alan R Kristal
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 B402, PO Box 19024, Seattle, WA 98109 1024, USA
    Am J Epidemiol 168:1416-24. 2008
    ..Genetic or environmental factors that affect the activity of 5-alpha-reductase may be important in the development of symptomatic BPH...
  36. ncbi request reprint SELDI-TOF MS whole serum proteomic profiling with IMAC surface does not reliably detect prostate cancer
    Dale McLerran
    Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Clin Chem 54:53-60. 2008
    ..This report is the 2nd of 2 companion articles describing a validation study of a SELDI-TOF MS approach with IMAC surface sample processing to identify prostatic adenocarcinoma...
  37. pmc Effects of screening on radical prostatectomy efficacy: the prostate cancer intervention versus observation trial
    Jing Xia
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    J Natl Cancer Inst 105:546-50. 2013
    ..1% to 6.5%) after 12 years. It is not known whether a higher frequency of screen detection in PIVOT explains the lower AMD...
  38. doi request reprint Primary scrotal cancer: disease characteristics and increasing incidence
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Urology 72:1139-43. 2008
    ..Using a population-based cancer registry, we describe the demographic and pathologic characteristics of scrotal cancer and report the incidence trends over time...
  39. pmc Male pattern baldness and prostate cancer risk in a population-based case-control study
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, WA, United States
    Cancer Epidemiol 34:131-5. 2010
    ..Studies exploring the relationship between the two conditions have been inconclusive. Using a population-based, case-control study of PCa, we explore the relationship between early-onset MPB and PCa risk...
  40. pmc Prostate cancer specific mortality and Gleason 7 disease differences in prostate cancer outcomes between cases with Gleason 4 + 3 and Gleason 3 + 4 tumors in a population based cohort
    Jonathan L Wright
    Department of Urology, University of Washington School of Public Health, Seattle, Washington 98195, USA
    J Urol 182:2702-7. 2009
    ..In this population based cohort we determined prostate cancer outcomes at different Gleason scores, particularly the different Gleason 7 patterns...
  41. doi request reprint Tertiary Gleason pattern 5 in Gleason 7 prostate cancer predicts pathological stage and biochemical recurrence
    Hong Gee Sim
    Department of Urology, University of Washington, Seattle, Washington 98195, USA
    J Urol 179:1775-9. 2008
    ..We studied the pathological and biochemical outcome following radical prostatectomy in men with Gleason sum 7 and tertiary Gleason pattern 5...
  42. ncbi request reprint Prostate cancer mortality in relation to screening by prostate-specific antigen testing and digital rectal examination: a population-based study in middle-aged men
    Ilir Agalliu
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M4 B874, Seattle, WA 98109, USA
    Cancer Causes Control 18:931-7. 2007
    ....
  43. doi request reprint Influence of publication of US and European prostate cancer screening trials on PSA testing practices
    Steven B Zeliadt
    Health Services Research and Development Center of Excellence, VA Puget Sound Health Care System, Seattle, WA 98101, USA
    J Natl Cancer Inst 103:520-3. 2011
    ..PSA testing among men older than 75 years initially declined slightly following the recommendations by the US Preventive Services Task Force in 2008 and continued to decline after the trial publications...
  44. ncbi request reprint Surgical management of prostate cancer
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, 1959 Northeast Pacific, Seattle, WA 98195, USA Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Hematol Oncol Clin North Am 27:1111-35, vii. 2013
    ..In addition, there is a review of the published literature on surgical ablative therapies for prostate cancer. ..
  45. pmc A study of caloric restriction versus standard diet in overweight men with newly diagnosed prostate cancer: a randomized controlled trial
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98109 1024, USA
    Prostate 73:1345-51. 2013
    ..We investigate whether a short-term caloric restriction diet in overweight/obese men with newly diagnosed PCa can lead to measurable changes in patient anthropometrics and insulin-related proteins...
  46. pmc Genetic variants in the LEPR, CRY1, RNASEL, IL4, and ARVCF genes are prognostic markers of prostate cancer-specific mortality
    Daniel W Lin
    Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
    Cancer Epidemiol Biomarkers Prev 20:1928-36. 2011
    ..The purpose of this study was to test whether variation in selected candidate genes in biological pathways of interest for prostate cancer progression could help distinguish patients at higher risk for fatal prostate cancer...
  47. ncbi request reprint New and novel markers for prostate cancer detection
    Michael C Risk
    Department of Urology, University of Washington Medical Center, Seattle, WA 98195, USA
    Curr Urol Rep 10:179-86. 2009
    ..Further study is needed to validate many of these markers, and the future of prostate cancer detection will likely lie in multiplex assays that test a number of markers concomitantly to assess prostate cancer risk...
  48. pmc Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity
    Stacia K Wyman
    Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Genome Res 21:1450-61. 2011
    ....
  49. ncbi request reprint The basic biochemistry and molecular events of hormone therapy
    Elahe A Mostaghel
    Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA 98109, USA
    Curr Urol Rep 8:224-32. 2007
    ....
  50. pmc Effect of collecting duct histology on renal cell cancer outcome
    Jonathan L Wright
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    J Urol 182:2595-9. 2009
    ..Recent surgical series of the condition showed conflicting results. We used an American population based data set to compare the survival experience of patients with collecting duct vs clear cell renal cell carcinoma...
  51. ncbi request reprint Incidence of primary urethral carcinoma in the United States
    Mia A Swartz
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Urology 68:1164-8. 2006
    ..Primary urethral carcinoma is rare, and the demographic correlates of its incidence have not been examined using population-based data...
  52. ncbi request reprint Value of urethral wash cytology in the retained male urethra after radical cystoprostatectomy
    Daniel W Lin
    Department of Urology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Urol 169:961-3. 2003
    ..We retrospectively evaluated the outcome in post-cystectomy urethrectomy cases at our institution from 1994 to 2000...
  53. doi request reprint Veterans Affairs Cooperative Studies Program study 553: Chemotherapy after prostatectomy, a phase III randomized study of prostatectomy versus prostatectomy with adjuvant docetaxel for patients with high-risk, localized prostate cancer
    Bruce Montgomery
    Veterans Affairs Puget Sound Health Care System and University of Washington, Seattle, Washington 98109, USA
    Urology 72:474-80. 2008
  54. pmc A preliminary exploration of the feasibility of offering men information about potential prostate cancer treatment options before they know their biopsy results
    Steven B Zeliadt
    Northwest HSR and D Center of Excellence, VA Puget Sound Health Care System, Metropolitan Park West, 1100 Olive Way 1400, Seattle, WA 98101, USA
    BMC Med Inform Decis Mak 13:19. 2013
    ..Priming men about the availability of multiple options before they have a confirmed diagnosis may be an opportunity to engage patients in more informed decision-making...
  55. ncbi request reprint Polymorphisms in the glutathione S-transferase M1, T1, and P1 genes and prostate cancer prognosis
    Ilir Agalliu
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Prostate 66:1535-41. 2006
    ..The aim of this study was to examine associations between GSTM1, T1, or P1 genetic variants and prostate cancer outcomes...
  56. ncbi request reprint Obesity is associated with increased risks of prostate cancer metastasis and death after initial cancer diagnosis in middle-aged men
    Zhihong Gong
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Cancer 109:1192-202. 2007
    ..The objective of this study was to examine associations between obesity and the risks of developing metastasis or prostate cancer-specific mortality in a population-based cohort of men with prostate cancer...
  57. pmc A multi-institutional matched-control analysis of adjuvant and salvage postoperative radiation therapy for pT3-4N0 prostate cancer
    Edouard J Trabulsi
    Department of Urology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Urology 72:1298-302; discussion 1302-4. 2008
    ..We studied a group of patients undergoing ART by comparing them with a matched control group undergoing SRT after biochemical failure...
  58. pmc Oxidative DNA damage in the prostate may predispose men to a higher risk of prostate cancer
    Jennifer D Wu
    Department of Medicine, University of Washington, Seattle, WA, USA
    Transl Oncol 2:39-45. 2009
    ....
  59. pmc What happens after an elevated PSA test: the experience of 13,591 veterans
    Steven B Zeliadt
    VA Health Services Research and Development Service, Department of Veterans Affairs Medical Center, Seattle, WA 98101, USA
    J Gen Intern Med 25:1205-10. 2010
    ..The occurrence and timing of prostate biopsy following an elevated prostate-specific antigen (PSA) test varied considerably in randomized screening trials...
  60. pmc The effect of demographic and clinical factors on the relationship between BMI and PSA levels
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Prostate 71:1631-7. 2011
    ..In this study we evaluated the potential confounding effect of these factors on the obesity-PSA relationship and evaluated the association between these factors and PSA level...
  61. ncbi request reprint Role of post-chemotherapy surgery in germ cell tumors
    Hong Gee Sim
    Department of Urology, University of Washington, Seattle, WA 98195, USA
    Urol Clin North Am 34:199-217; abstract ix. 2007
    ..Complete removal of all post-chemotherapy residual masses in nonseminomatous germ cell tumors remains the standard of care and allows for improved prognostication of the long-term oncologic and functional outcome...
  62. ncbi request reprint Tumor lysis syndrome in a patient with metastatic, androgen independent prostate cancer
    Jonathan L Wright
    Department of Urology, University of Washington, WA, USA
    Int J Urol 12:1012-3. 2005
    ..It is rarely described in patients with solid tumors. We report a case of TLS in a patient with metastatic adenocarcinoma of the prostate after treatment with paclitaxel chemotherapy...
  63. pmc Circumcision and the risk of prostate cancer
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, WA, USA
    Cancer 118:4437-43. 2012
    ..In particular, sexually transmitted infections (STIs) have been implicated in PCa etiology, and studies have found that the risk of acquiring a STI can be reduced with circumcision. Therefore, circumcision may reduce PCa risk...
  64. pmc Correlation between selenium concentrations and glutathione peroxidase activity in serum and human prostate tissue
    Yumie Takata
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    Prostate 69:1635-42. 2009
    ..Hence, we investigated the correlation between serum and prostate tissue selenium concentrations and prostate tissue activity of glutathione peroxidase (GPX), a major selenoenzyme with antioxidant properties...
  65. pmc Circulating microRNAs as stable blood-based markers for cancer detection
    Patrick S Mitchell
    Divisions of Human Biology, Clinical Research, and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Proc Natl Acad Sci U S A 105:10513-8. 2008
    ..Our results establish the measurement of tumor-derived miRNAs in serum or plasma as an important approach for the blood-based detection of human cancer...
  66. ncbi request reprint Differences in survival among patients with urachal and nonurachal adenocarcinomas of the bladder
    Jonathan L Wright
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Cancer 107:721-8. 2006
    ..The current study compares disease-specific characteristics and survival associated with urachal and nonurachal primary bladder adenocarcinomas...
  67. ncbi request reprint Incidence of testicular germ cell cancers in U.S. children: SEER program experience 1973 to 2000
    Thomas J Walsh
    Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Urology 68:402-5; discussion 405. 2006
    ..We analyzed a population-based cohort to determine whether the incidence trends of prepubertal testicular germ cell tumors have risen similarly to those seen in adult testicular tumors...
  68. ncbi request reprint Effect of medical castration on CD4+ CD25+ T cells, CD8+ T cell IFN-gamma expression, and NK cells: a physiological role for testosterone and/or its metabolites
    Stephanie T Page
    Department of Medicine, University of Washington, Seattle, WA, USA
    Am J Physiol Endocrinol Metab 290:E856-63. 2006
    ..In addition, sex steroids suppress NK cell proliferation. This study supports a complex physiological role for T and/or its metabolites in immune regulation...
  69. ncbi request reprint Trends in renal cancer surgery and patient provider characteristics associated with partial nephrectomy in the United States
    Michael P Porter
    University of Washington Department of Urology, VA Puget Sound Health Care System, Seattle, WA 98108, USA
    Urol Oncol 25:298-302. 2007
    ..We describe recent temporal trends in surgery for renal neoplasm and identified factors associated with partial nephrectomy...
  70. ncbi request reprint The increasing role of CAM in prostate cancer
    Gabrielle Zecha
    University of Washington, Seattle, USA
    JAAPA 17:37-40, 43-4. 2004
  71. ncbi request reprint Editorial comment on: marked gene transcript level alterations occur early during radical prostatectomy
    Daniel W Lin
    Eur Urol 53:345-6. 2008
  72. ncbi request reprint Fear of recurrence, treatment satisfaction, and quality of life after radical prostatectomy for prostate cancer
    Stacey L Hart
    Department of Psychology, Ryerson University, Toronto, ON, Canada
    Support Care Cancer 16:161-9. 2008
    ..The objective of this study was to examine treatment satisfaction (TS) as a moderator of the relationship between FOR and QOL...
  73. ncbi request reprint Does the who and how of surgery in bladder cancer matter?
    Paul H Lange
    J Clin Oncol 22:2762-4. 2004
  74. ncbi request reprint Prostate cancer in men using testosterone supplementation
    Franklin D Gaylis
    Division of Urology, University of California at San Diego Medical Center, San Diego, California, USA
    J Urol 174:534-8; discussion 538. 2005
    ..To increase awareness of this risk, we report on a series of patients in whom clinically significant prostate cancer developed and was presumed to be related to exogenous testosterone use...
  75. ncbi request reprint Editorial comment on "Treatment of nonretroperitoneal residual germ cell tumor masses"
    Daniel W Lin
    Urol Oncol 23:439-40. 2005
  76. pmc Predicting the outcome of salvage radiation therapy for recurrent prostate cancer after radical prostatectomy
    Andrew J Stephenson
    Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH 44195 0001, USA
    J Clin Oncol 25:2035-41. 2007
    ..We developed a nomogram to predict the probability of cancer control at 6 years after SRT for PSA-defined recurrence...
  77. ncbi request reprint Prognostic value of combined "triple"-reverse transcription-PCR analysis for prostate-specific antigen, human kallikrein 2, and prostate-specific membrane antigen mRNA in peripheral blood and lymph nodes of prostate cancer patients
    Ralf Kurek
    Department of Anatomy and Cell Biology, Philipps University, Marburg, Germany
    Clin Cancer Res 10:5808-14. 2004
    ....
  78. ncbi request reprint Microarray analysis and tumor classification
    Daniel W Lin
    N Engl J Med 355:960; author reply 960. 2006
  79. ncbi request reprint Statins and the risk of cancer
    Claudia A Salinas
    JAMA 295:2721; author reply 2721-2. 2006
  80. doi request reprint Phase III prevention trial of fenretinide in patients with resected non-muscle-invasive bladder cancer
    Anita L Sabichi
    Department of Clinical Cancer Prevention, The University of Texas M D Anderson Cancer Center, Houston, TX 77230 1439, USA
    Clin Cancer Res 14:224-9. 2008
    ..The study aims to evaluate the efficacy and toxicity of fenretinide in preventing tumor recurrence in patients with transitional cell carcinoma (TCC) of the bladder...
  81. ncbi request reprint Evidence that the human gene for prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1)
    Natalia Y Kedishvili
    Division of Molecular Biology and Biochemistry, School of Biological Sciences, University of Missouri Kansas City, Kansas City, Missouri 64110, USA
    J Biol Chem 277:28909-15. 2002
    ..The enzymatic properties and expression pattern of RalR1 in prostate epithelium suggest that it might play a role in the regulation of retinoid homeostasis in human prostate...