C-S Lin

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Human PDE5A gene encodes three PDE5 isoforms from two alternate promoters
    C S Lin
    Knuppe Molecular Urology Laboratory, School of Medicine, University of California, San Francisco, CA 94143 1695, USA
    Int J Impot Res 14:15-24. 2002
  2. ncbi request reprint Expression, distribution and regulation of phosphodiesterase 5
    Ching Shwun Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, University of California, 1657 Scott Street, Room 210, Box 1695, San Francisco, CA 94115, USA
    Curr Pharm Des 12:3439-57. 2006
  3. ncbi request reprint Vascular endothelial growth factor induces IP-10 chemokine expression
    Ching Shwun Lin
    Knuppe Molecular Urology Laboratory, University of California at San Francisco, San Francisco, CA 94143 1695, USA
    Biochem Biophys Res Commun 292:79-82. 2002
  4. ncbi request reprint Cyclic nucleotide signaling in cavernous smooth muscle
    Ching Shwun Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, University of California, San Francisco, CA 94143 1695, USA
    J Sex Med 2:478-91. 2005
  5. ncbi request reprint Cyclic AMP and cyclic GMP activate protein kinase G in cavernosal smooth muscle cells: old age is a negative factor
    C S Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143 1695, USA
    BJU Int 89:576-82. 2002
  6. ncbi request reprint Tissue expression, distribution, and regulation of PDE5
    C S Lin
    Department of Urology, University of California, San Francisco, CA 94115, USA
    Int J Impot Res 16:S8-S10. 2004
  7. ncbi request reprint Upregulation of monocyte chemoattractant protein 1 and effects of transforming growth factor-beta 1 in Peyronie's disease
    Ching Shwun Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143 1695, USA
    Biochem Biophys Res Commun 295:1014-9. 2002
  8. ncbi request reprint Intracavernosal injection of vascular endothelial growth factor induces nitric oxide synthase isoforms
    C S Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143, USA
    BJU Int 89:955-60. 2002
  9. ncbi request reprint Gene expression profiling of an arteriogenic impotence model
    C S Lin
    Knuppe Molecular Urology Laboratory, School of Medicine, University of California at San Francisco, San Francisco, CA 94143 1695, USA
    Biochem Biophys Res Commun 285:565-9. 2001
  10. ncbi request reprint Neurotrophic effects of vascular endothelial growth factor and neurotrophins on cultured major pelvic ganglia
    G Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA, USA
    BJU Int 92:631-5. 2003

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Human PDE5A gene encodes three PDE5 isoforms from two alternate promoters
    C S Lin
    Knuppe Molecular Urology Laboratory, School of Medicine, University of California, San Francisco, CA 94143 1695, USA
    Int J Impot Res 14:15-24. 2002
    ..Both promoters were upregulated by increasing concentrations of either cAMP or cGMP. Several transcription factor AP2 and Sp1-binding sequences identified in the promoters are likely to be the mediators of cAMP/cGMP-responsiveness...
  2. ncbi request reprint Expression, distribution and regulation of phosphodiesterase 5
    Ching Shwun Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, University of California, 1657 Scott Street, Room 210, Box 1695, San Francisco, CA 94115, USA
    Curr Pharm Des 12:3439-57. 2006
    ..Virtually all tissues and cell types express PDE5, with heart and cardiomyocytes being contentious. PDE5A1 and PDE5A2 are ubiquitous, but PDE5A3 is specific to smooth muscle...
  3. ncbi request reprint Vascular endothelial growth factor induces IP-10 chemokine expression
    Ching Shwun Lin
    Knuppe Molecular Urology Laboratory, University of California at San Francisco, San Francisco, CA 94143 1695, USA
    Biochem Biophys Res Commun 292:79-82. 2002
    ..Secretion of IP-10 into culture medium peaked at 4 h after treatment of human CSMC with 10 ng/ml of VEGF. Optimal VEGF dosage for IP-10 induction was 50 ng/ml when assayed with cells that were treated for 8 h...
  4. ncbi request reprint Cyclic nucleotide signaling in cavernous smooth muscle
    Ching Shwun Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, University of California, San Francisco, CA 94143 1695, USA
    J Sex Med 2:478-91. 2005
    ..The involvement of these molecules in the development of erectile dysfunction and the possibility of using them as therapeutic agents or targets are also discussed...
  5. ncbi request reprint Cyclic AMP and cyclic GMP activate protein kinase G in cavernosal smooth muscle cells: old age is a negative factor
    C S Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143 1695, USA
    BJU Int 89:576-82. 2002
    ..To investigate protein kinase G-I (PKG-I) expression and activation in cavernosal smooth muscle cells (CSMC) of young and old rats...
  6. ncbi request reprint Tissue expression, distribution, and regulation of PDE5
    C S Lin
    Department of Urology, University of California, San Francisco, CA 94115, USA
    Int J Impot Res 16:S8-S10. 2004
    ..Preliminary data suggest that hypoxia might down-regulate PDE5A promoters, implying an involvement of PDE5 in stuttering priapism...
  7. ncbi request reprint Upregulation of monocyte chemoattractant protein 1 and effects of transforming growth factor-beta 1 in Peyronie's disease
    Ching Shwun Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143 1695, USA
    Biochem Biophys Res Commun 295:1014-9. 2002
    ..Treatment with TGF-beta1-induced higher expression of MCP-1 but not CTGF in all three types of cells, with C cells being the most responsive. Based on these observations, we propose that MCP-1 could be a novel therapeutic target in PD...
  8. ncbi request reprint Intracavernosal injection of vascular endothelial growth factor induces nitric oxide synthase isoforms
    C S Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA 94143, USA
    BJU Int 89:955-60. 2002
    ....
  9. ncbi request reprint Gene expression profiling of an arteriogenic impotence model
    C S Lin
    Knuppe Molecular Urology Laboratory, School of Medicine, University of California at San Francisco, San Francisco, CA 94143 1695, USA
    Biochem Biophys Res Commun 285:565-9. 2001
    ..Finally, VEGF, whose induction has been identified in many other ischemic tissues, was not induced in corpus cavernous tissue of ligated rats...
  10. ncbi request reprint Neurotrophic effects of vascular endothelial growth factor and neurotrophins on cultured major pelvic ganglia
    G Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, CA, USA
    BJU Int 92:631-5. 2003
    ..To investigate the feasibility of using a ganglial culture system to screen various growth factors as potential therapeutic agents for pelvic nerve injuries...
  11. ncbi request reprint Isolation of two isoforms of phosphodiesterase 5 from rat penis
    C S Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, University of California San Francisco, California 94143 1695, USA
    Int J Impot Res 15:129-36. 2003
    ..International Journal of Impotence Research (2003) 15, 129-136. doi:10.1038/sj.ijir.3900983..
  12. ncbi request reprint Age-related decrease of protein kinase G activation in vascular smooth muscle cells
    C S Lin
    Knuppe Molecular Urology Laboratory, University of California, San Francisco, CA 94143 1695, USA
    Biochem Biophys Res Commun 287:244-8. 2001
    ..We propose that the reduced PKG-I activation may explain why vascular relaxation is decreased in older individuals...
  13. ncbi request reprint Effect of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 complex in cavernous nerve cryoablation
    D Bochinski
    Department of Urology, School of Medicine, University of California, San Francisco, California 94143 0738, USA
    Int J Impot Res 16:418-23. 2004
    ..The reverse effect was noted with the IGFBP-3 complex injection...
  14. ncbi request reprint Growth factor therapy and neuronal nitric oxide synthase
    C S Lin
    Department of Urology, University of California at San Francisco, San Francisco, California 94143 0738, USA
    Int J Impot Res 16:S38-9. 2004
    ..International Journal of Impotence Research (2004) 16, S38-S39. doi:10.1038/sj.ijir.3901214..
  15. ncbi request reprint Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats
    R S Rogers
    Knuppe Molecular Urology Laboratory, Department of Urology, University of California School of Medicine, 94143, USA
    Int J Impot Res 15:26-37. 2003
    ..Intracavernous injection of either VEGF protein or VEGF gene may be a preferred therapy to preserve erectile function in patients in whom testosterone therapy is contraindicated...
  16. ncbi request reprint Identification and regulation of human PDE5A gene promoter
    C S Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, California 94143 1695, USA
    Biochem Biophys Res Commun 280:684-92. 2001
    ..DNase I footprint analysis identified four AP2- and two Sp1-binding sites in the 5' extension and four Sp1-binding sites in the 3' extensions. Cyclic AMP and cGMP had similar stimulatory effects on the PDE5A promoter...
  17. ncbi request reprint Vascular endothelial growth factor promotes proliferation and migration of cavernous smooth muscle cells
    X Liu
    Knuppe Molecular Urology Laboratory, Department of Urology, School of Medicine, University of California, San Francisco, California, USA
    J Urol 166:354-60. 2001
    ..Cavernous smooth muscle cells responded to VEGF in terms of cell proliferation and migration. Cavernous smooth muscle cells from rats of different ages expressed different levels of VEGFR-1 but did not express VEGFR-2...
  18. ncbi request reprint Expression of three isoforms of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in human penile cavernosum
    C S Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, University of California, San Francisco, California 94143 1695, USA
    Biochem Biophys Res Commun 268:628-35. 2000
    ..75, and 6.06 microM, respectively. Their cGMP-catalytic activities were inhibited by zaprinast with IC(50) values of 3.2 microM, 1.3 microM, and 1.6 microM, respectively, and by sildenafil with IC(50) of 28, 14, and 13 nM, respectively...
  19. ncbi request reprint Identification of three alternative first exons and an intronic promoter of human PDE5A gene
    C S Lin
    Knuppe Molecular Urology Laboratory, Department of Urology, University of California, San Francisco, California 94143 1695, USA
    Biochem Biophys Res Commun 268:596-602. 2000
    ..However, the sequence bound by AP-2 (5'-GGGAAACGCTCGCGGGAGAGTTGG) is unusual in that it bears little resemblance to the consensus AP-2-binding sequence...
  20. ncbi request reprint Upregulation of L-plastin gene by testosterone in breast and prostate cancer cells: identification of three cooperative androgen receptor-binding sequences
    C S Lin
    Department of Urology, University of California, San Francisco 94143, USA
    DNA Cell Biol 19:1-7. 2000
    ....
  21. ncbi request reprint The murine L-plastin gene promoter: identification and comparison with the human L-plastin gene promoter
    C S Lin
    Department of Stomatology, University of California, San Francisco 94143 0512, USA
    DNA Cell Biol 16:9-16. 1997
    ..This AP1/ER hybrid sequence was incapable of binding to ER. However, both human and murine promoters were found to function equally well in either human or murine leukocytes...
  22. ncbi request reprint The effect of adeno-associated virus mediated brain derived neurotrophic factor in an animal model of neurogenic impotence
    M E Bakircioglu
    Department of Urology, University of California School of Medicine, San Francisco, California 94143-0738, USA
    J Urol 165:2103-9. 2001
    ....
  23. ncbi request reprint Decreased trabecular smooth muscle and caveolin-1 expression in the penile tissue of aged rats
    M E Bakircioglu
    Knuppe Molecular Urology Laboratory, Department of Urology, University of California-San Francisco, San Francisco, California 94115-3465, USA
    J Urol 166:734-8. 2001
    ..CONCLUSIONS: In these aged rats the decreased ratio of trabecular smooth muscle-to-collagen and the reduced expression of caveolin-1 may contribute to erectile dysfunction...
  24. ncbi request reprint The effect of vascular endothelial growth factor and brain-derived neurotrophic factor on cavernosal nerve regeneration in a nerve-crush rat model
    P S Hsieh
    Department of Urology, University of California, San Francisco, CA 94143, USA
    BJU Int 92:470-5. 2003
    ....
  25. ncbi request reprint Wogonin suppresses cellular proliferation and expression of monocyte chemoattractant protein 1 in Peyronie's plaque-derived cells
    Z Wang
    Department of Urology, School of Medicine, University of California, San Francisco, USA
    BJU Int 92:753-7. 2003
    ..To test the effect of wogonin on cellular proliferation and expression of monocyte chemoattractant protein 1 (MCP-1) in cells derived from normal and diseased tunica albuginea (TA), as related to Peyronie's disease (PD)...
  26. ncbi request reprint Overexpression of c-met in oral SCC promotes hepatocyte growth factor-induced disruption of cadherin junctions and invasion
    M Murai
    Department of Stomatology, University of California San Francisco, San Francisco, CA 94143, USA
    Int J Oncol 25:831-40. 2004
    ..Collectively, these results suggest that HGF/c-Met signaling is a common event in oral SCC that may trigger phenotype modulation and enhanced invasion and metastasis...
  27. ncbi request reprint Sequence and expression of a cDNA encoding the mouse homologue of the rat ribosomal protein L28
    P S Burke
    Department of Genetics and Development, Columbia University, College of Physicians and Surgeons, New York, NY 10032
    Gene 142:315-6. 1994
    ..Northern blot hybridization analysis detected a single transcript in embryo, placenta and adult tissues...
  28. pmc Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts
    C S Lin
    Institute for Medical Research, San Jose, California 95128
    Mol Cell Biol 8:4659-68. 1988
    ..The leukocyte isoform l-plastin is expressed in a diverse variety of human tumor cell lines, suggesting that it may be involved in the neoplastic process of some solid human tumors...
  29. ncbi request reprint Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat
    C M Ambrose
    Molecular Neurogenetics Unit, Massachusetts General Hospital, Boston 02114
    Somat Cell Mol Genet 20:27-38. 1994
    ..Taken together, these observations suggest that the dominant HD mutation either confers a new property on the mRNA or, more likely, alters an interaction at the protein level...
  30. pmc Fimbrin is a homologue of the cytoplasmic phosphoprotein plastin and has domains homologous with calmodulin and actin gelation proteins
    M V de Arruda
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts
    J Cell Biol 111:1069-79. 1990
    ..Neoplastic cells derived from solid tissues express both isoforms. The differences in expression, sequence, and phosphorylation suggest possible functional differences between fimbrin isoforms...
  31. ncbi request reprint Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities
    Z C Xin
    Department of Urology, The 1st Hospital, Peking University, 8 Xishiku Street, Xicheng District, Beijing 100034, China
    Asian J Androl 5:15-8. 2003
    ..To clarify the mechanism of the therapeutic action of icariin on erectile dysfunction (ED)...
  32. pmc Correction of the N-terminal sequences of the human plastin isoforms by using anchored polymerase chain reaction: identification of a potential calcium-binding domain
    C S Lin
    California Institute for Medical Research, San Jose 95128
    Mol Cell Biol 10:1818-21. 1990
    ..We used the anchored polymerase chain reaction technique to amplify and clone the missing 5' ends of plastin mRNAs. We found that both plastin isoforms contain a potential calcium binding site near the N terminus...
  33. ncbi request reprint Cloning of the alpha-adducin gene from the Huntington's disease candidate region of chromosome 4 by exon amplification
    S A Taylor
    Molecular Neurogenetics Unit, Massachusetts General Hospital, Boston
    Nat Genet 2:223-7. 1992
    ..The alpha-adducin gene maps immediately telomeric to D4S95, in a region likely to contain the HD defect, and must be scrutinized to establish whether it is the site of the HD mutation...
  34. ncbi request reprint Human fibroblast tropomyosin isoforms: characterization of cDNA clones and analysis of tropomyosin isoform expression in human tissues and in normal and transformed cells
    R E Novy
    Department of Biological Sciences, University of Iowa, Iowa City 52242 1324
    Cell Motil Cytoskeleton 25:267-81. 1993
    ..However, there was no detectable expression of this exon in stomach and skeletal muscle. The difference in tissue-specific expression suggests that different isoforms may perform distinct functions in different tissues...
  35. pmc Identification of I-plastin, a human fimbrin isoform expressed in intestine and kidney
    C S Lin
    Research Institute, Palo Alto Medical Foundation, California 94301
    Mol Cell Biol 14:2457-67. 1994
    ..Immunofluorescence microscopy detected I-plastin in the brush border of the small intestine and colon. These results identify I-plastin as the human homolog of chicken intestine fimbrin and as a third plastin isoform in humans...
  36. ncbi request reprint Differentially transcribed genes in skeletal muscle of Duroc and Taoyuan pigs
    C S Lin
    Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 300, Taiwan, Republic of China
    J Anim Sci 83:2075-86. 2005
    ..These results suggest that SLIM1 may be useful for the development of markers associated with the postnatal muscle growth of pigs...
  37. ncbi request reprint The role of HNF-1alpha in controlling hepatic catalase activity
    V Muppala
    Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan
    Mol Pharmacol 57:93-100. 2000
    ..Furthermore, our results of cell transfection and luciferase reporter assay indicated that the mouse ferrochelatase promoter could be trans-activated directly by HNF-1alpha...
  38. ncbi request reprint Characterization of the human L-plastin gene promoter in normal and neoplastic cells
    C S Lin
    Laboratory of Cancer Cell Biology, Palo Alto Medical Foundation Research Institute, California 94301
    J Biol Chem 268:2793-801. 1993
    ..The potential significance of regulation of the L-plastin gene by reproductive hormones in cancers arising in hormone-responsive tissues is also discussed...
  39. ncbi request reprint Human plastin genes. Comparative gene structure, chromosome location, and differential expression in normal and neoplastic cells
    C S Lin
    Laboratory of Cancer Cell Biology, Palo Alto Medical Foundation Research Institute, California 94301
    J Biol Chem 268:2781-92. 1993
    ..Finally, we present evidence that fimbrin is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine...
  40. ncbi request reprint Alternative extracellular and cytoplasmic domains of the integrin alpha 7 subunit are differentially expressed during development
    B L Ziober
    Department of Stomatology and Anatomy, University of California, San Francisco 94143
    J Biol Chem 268:26773-83. 1993
    ....
  41. ncbi request reprint Development of hematopoietic cells lacking transcription factor GATA-1
    L Pevny
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032
    Development 121:163-72. 1995
    ....
  42. ncbi request reprint Trace elements in cultured tilapia (Oreochromis mossambicus): results from a farm in Southern Taiwan
    T S Lin
    Department of Environmental Engineering and Health, Yuanpei University of Science and Technology, 306 Yuan Pei Street, Hsin Chu City Taiwan 300
    Bull Environ Contam Toxicol 74:308-13. 2005
  43. ncbi request reprint Establishment and characterization of a spontaneously immortalized porcine mammary epithelial cell line
    Y L Sun
    Division of Biotechnology, Animal Technology Institute Taiwan, No 52, Kedong 2nd Road, P O Box 23, Chunan 350, Miaoli, Taiwan, ROC
    Cell Biol Int 30:970-6. 2006
    ..To our knowledge, this is the first report of an immortalized mammary epithelial cell line from pig...
  44. ncbi request reprint Gene transfection and expression in a primary culture of mammary epithelial cells isolated from lactating sows
    Y L Sun
    Division of Biotechnology, Animal Technology Institute Taiwan, P O Box 23, Chunan 350, Miaoli, Taiwan, ROC
    Cell Biol Int 29:576-82. 2005
    ..The established PMECs maintained optimal gene expression from 1 to 20 passages and appeared to provide an efficient and convenient system for assessing the expression of transgenes containing mammary gland-specific promoters...
  45. doi request reprint Expression of recombinant anticoagulant hirudin in the differentiated cultures of the porcine mammary epithelial cell line SI-PMEC
    Y L Sun
    Division of Biotechnology, Animal Technology Institute, Taiwan, P O Box 23, Chunan 35099, Miaoli, Taiwan
    Cell Biol Int 32:739-47. 2008
    ..5-0.6microg of recombinant hirudin/mg of total cellular protein. These results suggest that the established SI-PMEC cells have pharmaceutical potential to inducibly express bioactive heterogeneous proteins...
  46. ncbi request reprint Structural and biochemical evidence of mitochondrial depletion in pigs with hypertrophic cardiomyopathy
    C S Lin
    Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan
    Res Vet Sci 74:219-26. 2003
    ..In conclusion, our results reveal that a secondary effect of tissue-specific mtDNA depletion and mitochondrial dysfunction is in response to the HCM...
  47. ncbi request reprint The genomic structure of the human skeletal muscle sodium channel gene
    A I McClatchey
    Molecular Neurogenetics Laboratory, Massachusetts General Hospital, Charlestown 02129
    Hum Mol Genet 1:521-7. 1992
    ..Knowledge of the exon structure and flanking intron sequences for SCN4A will permit a systematic search for mutations in PMC and HPP...
  48. ncbi request reprint A shortened life span of EKLF-/- adult erythrocytes, due to a deficiency of beta-globin chains, is ameliorated by human gamma-globin chains
    S K Lim
    Department of Genetics and Development, Columbia University, New York, NY 10032, USA
    Blood 90:1291-9. 1997
    ....
  49. ncbi request reprint Increased expression of the distal, but not of the proximal, Gata1 transcripts during differentiation of primary erythroid cells
    A M Vannucchi
    Division of Hematology, University of Florence and Azienda Ospedale Careggi, Italy
    J Cell Physiol 180:390-401. 1999
    ....
  50. ncbi request reprint Age-associated changes in collagen content and its subtypes within rat corpora cavernosa with computerized histomorphometric analysis
    J S Lin
    Division of Andrology, Department of Urology, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan
    Urology 57:837-42. 2001
    ..However, the relative proportion of each subtype did not change with age. Therefore, we conclude that the amount of collagen may only partly contribute to erectile dysfunction in the aging process of the rat...
  51. ncbi request reprint The human erythropoietin receptor gene rescues erythropoiesis and developmental defects in the erythropoietin receptor null mouse
    X Yu
    Laboratory of Chemical Biology, National Institute of Diabetes and Digestive and Kidney Disorders, National Institutes of Health, Bethesda, MD 20892 1822, USA
    Blood 98:475-7. 2001
    ....
  52. ncbi request reprint Expression of transforming growth factor-beta 1 and alpha-smooth muscle actin of myofibroblast in the pathogenesis of nasal polyps
    C H Chang
    Department of Otolaryngology, Kaohsiung Medical University, No. 100, Shih-Chuan 1st Road, Kaohsiung City 807, Taiwan
    Kaohsiung J Med Sci 17:133-8. 2001
    ..TGF-beta 1 produced by inflammatory cells can influence the development of myofibroblasts which in turn can induce extracellular matrix accumulation and, therefore, TGF-beta 1 plays a important role in the formation of nasal polyps...
  53. ncbi request reprint Traumatic arteriogenic erectile dysfunction: a rat model
    A El-Sakka
    Suez Canal University, Ismailia, Egypt
    Int J Impot Res 13:162-71. 2001
    ..Bilateral ligation of internal iliac arteries produces a reliable animal model for traumatic arteriogenic ED. Further studies are needed to investigate the molecular mechanism of ED in this model...
  54. ncbi request reprint Dnmt3L and the establishment of maternal genomic imprints
    D Bourc'his
    Department of Genetics and Development, Transgenic Animal Facility, Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Science 294:2536-9. 2001
    ..The key catalytic motifs characteristic of DNA cytosine methyltransferases have been lost from Dnmt3L, and the protein is more likely to act as a regulator of imprint establishment than as a DNA methyltransferase...
  55. pmc Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
    S Srinivas
    Department of Genetics and Development, Columbia University, New York, USA
    BMC Dev Biol 1:4. 2001
    ....
  56. ncbi request reprint Aquapuncture therapy of repeat breeding in dairy cattle
    J H Lin
    Department of Animal Science, National Taiwan University, Taipei, ROC
    Am J Chin Med 30:397-404. 2002
    ..However, the final result obtained from actual delivery of fetus in the experimental animals was only 8/18 (44.4%)...
  57. ncbi request reprint Involvement of the terminus of grouper betanodavirus capsid protein in virus-like particle assembly
    M W Lu
    Institute of Marine Resources, National Sun Yat Sen University, Kaohsiung, Taiwan
    Arch Virol 148:345-55. 2003
    ..The ability of VLP formation diminished when 4 to 11 C-terminal residues were deleted. The termini that can be deleted without seriously destructing the VLPs are 25 and 3 residues at N- and C-termini, respectively...
  58. pmc Cloning and characterization of a cDNA encoding transformation-sensitive tropomyosin isoform 3 from tumorigenic human fibroblasts
    C S Lin
    Armand Hammer Cancer Research Center, Linus Pauling Institute of Science and Medicine, Palo Alto, California 94306
    Mol Cell Biol 8:160-8. 1988
    ..In contrast to Tm4 and Tm5, Tm3 has a small gene family, with, at best, only one pseudogene...