Alan R Light

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. ncbi Evidence for a heritable predisposition to Chronic Fatigue Syndrome
    Frederick Albright
    Pharmacotherapy Outcomes Research Center, Department of Pharmacotherapy, College of Pharmacy, University of Utah, USA
    BMC Neurol 11:62. 2011
  2. ncbi Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1
    Alan R Light
    Department of Anethesiology, University of Utah School of Medicine, Salt Lake City, UT 84132 2304, USA
    J Neurophysiol 100:1184-201. 2008
  3. ncbi Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome
    A R Light
    Department of Anesthesiology The Brain Institute Department of Neurobiology and Anatomy Department of Exercise and Sport Science, University of Utah, Salt Lake City, UT 84132, USA
    J Intern Med 271:64-81. 2012
  4. ncbi Moderate exercise increases expression for sensory, adrenergic, and immune genes in chronic fatigue syndrome patients but not in normal subjects
    Alan R Light
    Department of Anesthesiology, University of Utah, Salt Lake City, Utah 84132 2304, USA
    J Pain 10:1099-112. 2009
  5. ncbi Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with multiple sclerosis, and healthy controls
    Andrea T White
    Department of Anesthesiology, University of Utah, 30 N 1900 E, Room 3C444, Salt Lake City, UT 84132 2501, USA
    Psychosom Med 74:46-54. 2012
  6. ncbi Severity of symptom flare after moderate exercise is linked to cytokine activity in chronic fatigue syndrome
    Andrea T White
    Department of Exercise and Sport Science, University of Utah, Salt Lake City, Utah, USA
    Psychophysiology 47:615-24. 2010
  7. ncbi A bacterial source for mollusk pyrone polyketides
    Zhenjian Lin
    Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT 84112, USA
    Chem Biol 20:73-81. 2013
  8. ncbi Absence of XMRV retrovirus and other murine leukemia virus-related viruses in patients with chronic fatigue syndrome
    Clifford H Shin
    Department of Pathology, University of Utah, 15 North Medical Drive East, Suite 2100, Salt Lake City, UT 84112, USA
    J Virol 85:7195-202. 2011
  9. ncbi Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP
    Cassandra E Deering-Rice
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States
    Chem Res Toxicol 24:950-9. 2011
  10. ncbi Totopotensamides, polyketide-cyclic peptide hybrids from a mollusk-associated bacterium Streptomyces sp
    Zhenjian Lin
    College of Pharmacy, Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA
    J Nat Prod 75:644-9. 2012

Collaborators

  • Kathleen C Light
  • Andrea T White
  • Russell W Teichert
  • Jie Zhang
  • Ila R Singh
  • Harry R Hill
  • Jeewoo Lee
  • John M Veranth
  • Zhenjian Lin
  • Ronald W Hughen
  • Gisela P Concepcion
  • Baldomero M Olivera
  • Eric W Schmidt
  • Olivier Peraud
  • Malem Flores
  • Margo G Haygood
  • Christopher A Reilly
  • Lucinda Bateman
  • Clifford H Shin
  • Frederick Albright
  • Cassandra E Deering-Rice
  • Jason C Kwan
  • Mary Anne Ammon
  • Ma Diarey Tianero
  • Joshua P Torres
  • Aaron Joseph L Villaraza
  • James E Cox
  • Lenny Marett
  • Niel M Henriksen
  • Imelda Forteza
  • Gary Rosenberg
  • Thomas E Cheatham
  • Christopher J Leonard
  • Lisa A Cannon-Albright
  • Ashley M Bunker
  • Erin G Romero
  • Garold S Yost
  • Robert Schlaberg
  • Darien Shapiro
  • Jason S Biggs

Detail Information

Publications12

  1. ncbi Evidence for a heritable predisposition to Chronic Fatigue Syndrome
    Frederick Albright
    Pharmacotherapy Outcomes Research Center, Department of Pharmacotherapy, College of Pharmacy, University of Utah, USA
    BMC Neurol 11:62. 2011
    ....
  2. ncbi Dorsal root ganglion neurons innervating skeletal muscle respond to physiological combinations of protons, ATP, and lactate mediated by ASIC, P2X, and TRPV1
    Alan R Light
    Department of Anethesiology, University of Utah School of Medicine, Salt Lake City, UT 84132 2304, USA
    J Neurophysiol 100:1184-201. 2008
    ..We further conclude that the adequate stimuli for muscle metaboreceptors and nociceptors are combinations of protons, ATP, and lactate...
  3. ncbi Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome
    A R Light
    Department of Anesthesiology The Brain Institute Department of Neurobiology and Anatomy Department of Exercise and Sport Science, University of Utah, Salt Lake City, UT 84132, USA
    J Intern Med 271:64-81. 2012
    ....
  4. ncbi Moderate exercise increases expression for sensory, adrenergic, and immune genes in chronic fatigue syndrome patients but not in normal subjects
    Alan R Light
    Department of Anesthesiology, University of Utah, Salt Lake City, Utah 84132 2304, USA
    J Pain 10:1099-112. 2009
    ..These findings suggest possible new causes, points for intervention, and objective biomarkers for these disorders...
  5. ncbi Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with multiple sclerosis, and healthy controls
    Andrea T White
    Department of Anesthesiology, University of Utah, 30 N 1900 E, Room 3C444, Salt Lake City, UT 84132 2501, USA
    Psychosom Med 74:46-54. 2012
    ....
  6. ncbi Severity of symptom flare after moderate exercise is linked to cytokine activity in chronic fatigue syndrome
    Andrea T White
    Department of Exercise and Sport Science, University of Utah, Salt Lake City, Utah, USA
    Psychophysiology 47:615-24. 2010
    ..05). Thus, in CFS, cytokine activity may vary directly with SF, which may explain prior inconsistent findings...
  7. ncbi A bacterial source for mollusk pyrone polyketides
    Zhenjian Lin
    Department of Medicinal Chemistry, University of Utah, Salt Lake City, UT 84112, USA
    Chem Biol 20:73-81. 2013
    ..The natural roles of nocapyrones are unknown, but they are active in neurological assays, revealing that mollusks with external shells are an overlooked source of secondary metabolite diversity...
  8. ncbi Absence of XMRV retrovirus and other murine leukemia virus-related viruses in patients with chronic fatigue syndrome
    Clifford H Shin
    Department of Pathology, University of Utah, 15 North Medical Drive East, Suite 2100, Salt Lake City, UT 84112, USA
    J Virol 85:7195-202. 2011
    ..Our findings do not support an association between CFS and MLV-related viruses, including XMRV, and the off-label use of antiretrovirals for the treatment of CFS does not seem justified at present...
  9. ncbi Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP
    Cassandra E Deering-Rice
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, United States
    Chem Res Toxicol 24:950-9. 2011
    ..It is concluded that TRPA1 is a specific target for electrophilic chemical components of DEP and proposed that activation of TRPA1 in the respiratory tract is likely to be an important mechanism for DEP pneumotoxicity...
  10. ncbi Totopotensamides, polyketide-cyclic peptide hybrids from a mollusk-associated bacterium Streptomyces sp
    Zhenjian Lin
    College of Pharmacy, Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA
    J Nat Prod 75:644-9. 2012
    ..The application of Marfey's method to phenylglycine derivatives was explored using quantum mechanical calculations and NMR...
  11. ncbi Functional profiling of neurons through cellular neuropharmacology
    Russell W Teichert
    Department of Biology, University of Utah, Salt Lake City, UT 84112, USA
    Proc Natl Acad Sci U S A 109:1388-95. 2012
    ....
  12. ncbi Microhabitats within venomous cone snails contain diverse actinobacteria
    Olivier Peraud
    Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA
    Appl Environ Microbiol 75:6820-6. 2009
    ..This suggests that cone snails may represent an underexplored reservoir of novel actinomycetes of potential interest for drug discovery...