Israel Liberzon

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc mu-Opioid receptors and limbic responses to aversive emotional stimuli
    Israel Liberzon
    Department of Psychiatry, Veterans Administration Medical Center, University of Michigan, Ann Arbor, MI 48105, USA
    Proc Natl Acad Sci U S A 99:7084-9. 2002
  2. ncbi request reprint Paralimbic and medial prefrontal cortical involvement in neuroendocrine responses to traumatic stimuli
    Israel Liberzon
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Psychiatry 164:1250-8. 2007
  3. ncbi request reprint Altered central micro-opioid receptor binding after psychological trauma
    Israel Liberzon
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0118, USA
    Biol Psychiatry 61:1030-8. 2007
  4. ncbi request reprint Neuroimaging studies of emotional responses in PTSD
    Israel Liberzon
    Trauma Stress and Anxiety Research Group, Department of Psychiatry, Ann Arbor VA Healthcare System, University of Michigan, 1500 E Medical Center Drive UH9D 0118, Ann Arbor, MI 48109 0118, USA
    Ann N Y Acad Sci 1071:87-109. 2006
  5. ncbi request reprint Increased psychiatric morbidity after abdominal aortic surgery: risk factors for stress-related disorders
    Israel Liberzon
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
    J Vasc Surg 43:929-34. 2006
  6. ncbi request reprint The functional neuroanatomy of PTSD: a critical review
    Israel Liberzon
    Department of Psychiatry, University of Michigan, MCHC, F6135, Ann Arbor, MI 48109, USA
    Prog Brain Res 167:151-69. 2008
  7. ncbi request reprint Neural correlates of traumatic recall in posttraumatic stress disorder
    Israel Liberzon
    Psychiatry Service, Ann Arbor Veterans Affairs Medical Center, MI 48109, USA
    Stress 6:151-6. 2003
  8. ncbi request reprint Extended amygdala and emotional salience: a PET activation study of positive and negative affect
    Israel Liberzon
    Department of Psychiatry, University of Michigan, Ann Arbor, USA
    Neuropsychopharmacology 28:726-33. 2003
  9. ncbi request reprint Corticolimbic blood flow during nontraumatic emotional processing in posttraumatic stress disorder
    K Luan Phan
    Department of Psychiatry, Pritzker School of Medicine, The University of Chicago, Chicago, Ill, USA
    Arch Gen Psychiatry 63:184-92. 2006
  10. pmc Effects of perceived control and cognitive coping on endocrine stress responses to pharmacological activation
    James L Abelson
    Department of Psychiatry, Trauma, Stress and Anxiety Research Group, Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, Michigan, USA
    Biol Psychiatry 64:701-7. 2008

Research Grants

  1. Cognition-Emotion-HPA Interaction: Translation Network
    Israel Liberzon; Fiscal Year: 2007
  2. Mental Health Research Education Grant (R25)
    Israel Liberzon; Fiscal Year: 2007

Detail Information

Publications80

  1. pmc mu-Opioid receptors and limbic responses to aversive emotional stimuli
    Israel Liberzon
    Department of Psychiatry, Veterans Administration Medical Center, University of Michigan, Ann Arbor, MI 48105, USA
    Proc Natl Acad Sci U S A 99:7084-9. 2002
    ..This is consistent with an inhibitory/anxiolytic role of the endogenous opioid system in limbic regions of the temporal lobe and basal forebrain...
  2. ncbi request reprint Paralimbic and medial prefrontal cortical involvement in neuroendocrine responses to traumatic stimuli
    Israel Liberzon
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
    Am J Psychiatry 164:1250-8. 2007
    ..The authors used [(15)O]H(2)O positron emission tomography (PET) on subjects with posttraumatic stress disorder (PTSD) to study these circuits...
  3. ncbi request reprint Altered central micro-opioid receptor binding after psychological trauma
    Israel Liberzon
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0118, USA
    Biol Psychiatry 61:1030-8. 2007
    ..The mu-opioid neurotransmitter system, implicated in responses to stress and suppression of pain, is distributed in and is thought to regulate the function of brain regions that are implicated in affective processing...
  4. ncbi request reprint Neuroimaging studies of emotional responses in PTSD
    Israel Liberzon
    Trauma Stress and Anxiety Research Group, Department of Psychiatry, Ann Arbor VA Healthcare System, University of Michigan, 1500 E Medical Center Drive UH9D 0118, Ann Arbor, MI 48109 0118, USA
    Ann N Y Acad Sci 1071:87-109. 2006
    ..Further links between functional neuroanatomy of emotional responses and neuroendocrine stress regulation are proposed...
  5. ncbi request reprint Increased psychiatric morbidity after abdominal aortic surgery: risk factors for stress-related disorders
    Israel Liberzon
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
    J Vasc Surg 43:929-34. 2006
    ..These complications are also expected after abdominal aortic surgery, but their incidence and relevant risk factors in this population have not been documented...
  6. ncbi request reprint The functional neuroanatomy of PTSD: a critical review
    Israel Liberzon
    Department of Psychiatry, University of Michigan, MCHC, F6135, Ann Arbor, MI 48109, USA
    Prog Brain Res 167:151-69. 2008
    ..It is proposed that the mPFC plays a role in the "contextualization" of stimuli, and dysregulation of contextualization processes might play a key role in the generation of PTSD symptoms...
  7. ncbi request reprint Neural correlates of traumatic recall in posttraumatic stress disorder
    Israel Liberzon
    Psychiatry Service, Ann Arbor Veterans Affairs Medical Center, MI 48109, USA
    Stress 6:151-6. 2003
    ....
  8. ncbi request reprint Extended amygdala and emotional salience: a PET activation study of positive and negative affect
    Israel Liberzon
    Department of Psychiatry, University of Michigan, Ann Arbor, USA
    Neuropsychopharmacology 28:726-33. 2003
    ....
  9. ncbi request reprint Corticolimbic blood flow during nontraumatic emotional processing in posttraumatic stress disorder
    K Luan Phan
    Department of Psychiatry, Pritzker School of Medicine, The University of Chicago, Chicago, Ill, USA
    Arch Gen Psychiatry 63:184-92. 2006
    ..However, the relationship between activity in these regions and general emotional processing unrelated to traumatic experience has not been fully examined...
  10. pmc Effects of perceived control and cognitive coping on endocrine stress responses to pharmacological activation
    James L Abelson
    Department of Psychiatry, Trauma, Stress and Anxiety Research Group, Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, Michigan, USA
    Biol Psychiatry 64:701-7. 2008
    ..This study attempted to identify the core factors that modulate HPA axis activity in this model...
  11. pmc Neural dysregulation in posttraumatic stress disorder: evidence for disrupted equilibrium between salience and default mode brain networks
    Rebecca K Sripada
    Departments of Psychology, University of Michigan, Ann Arbor, Michigan, USA
    Psychosom Med 74:904-11. 2012
    ..This might be linked to aberrations in large-scale networks subserving the detection of salient stimuli (i.e., the salience network [SN]) and stimulus-independent, internally focused thought (i.e., the default mode network [DMN])...
  12. ncbi request reprint Corticolimbic blood flow in posttraumatic stress disorder during script-driven imagery
    Jennifer C Britton
    Neuroscience Program, University of Michigan, Michigan, USA
    Biol Psychiatry 57:832-40. 2005
    ..The present study examined both PTSD-specific and trauma-specific regional cerebral blood flow (rCBF) patterns during script-driven imagery...
  13. ncbi request reprint Subjective rating of emotionally salient stimuli modulates neural activity
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 18:650-9. 2003
    ..For both RTNG and PSVW, subjects activated the left fusiform gyrus. The results support the proposition that task instructions about how subjects should process evocative stimuli can affect neural activity...
  14. doi request reprint Medial prefrontal cortex and right insula activity predict plasma ACTH response to trauma recall
    Anthony P King
    Psychiatry, University of Michigan, Ann Arbor, MI, USA
    Neuroimage 47:872-80. 2009
    ..These results support the hypotheses that right insula is involved in psychological activation of the LHPA axis and that rostral mPFC may negatively modulate LHPA axis responses...
  15. pmc Social appraisal in chronic psychosis: role of medial frontal and occipital networks
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Rd, Ann Arbor MI 48109 2700, USA
    J Psychiatr Res 45:526-38. 2011
    ....
  16. doi request reprint Trait anxiety modulates anterior cingulate activation to threat interference
    Heide Klumpp
    Department of Psychiatry, University of Michigan Ann Arbor, 4250 Plymouth Road, Ann Arbor, MI 48109, USA
    Depress Anxiety 28:194-201. 2011
    ..anterior cingulate cortex, "ACC") might play a role. In this study, we explored the hypothesis that trait anxiety would be associated with ACC activity in an attentional control task with varying levels of threat interference...
  17. ncbi request reprint Medial frontal hyperactivity in reality distortion
    Stephan F Taylor
    Department of Psychiatry, University of Michigan Medical Center, Ann Arbor, Michigan 48109 5765, USA
    Biol Psychiatry 61:1171-8. 2007
    ..The amygdala interacts with MPFC, also carries out socioemotional processing, and has been implicated in schizophrenia; thus, we also tested the hypothesis that patients would exhibit aberrant amygdala activity...
  18. pmc Corticolimbic brain reactivity to social signals of threat before and after sertraline treatment in generalized social phobia
    K Luan Phan
    Department of Psychiatry, University of Illinois at Chicago, and Mental Health Service Line, Jesse Brown VA Medical Center, Chicago, IL 60608, USA
    Biol Psychiatry 73:329-36. 2013
    ..Although selective serotonin reuptake inhibitor (SSRI) treatment is known to be an effective treatment, little is known about the mechanism through which these agents exert their anxiolytic effects at a brain level in gSP...
  19. doi request reprint Relationship between anxiety, depression, and health satisfaction among veterans with PTSD
    Sheila A M Rauch
    VA Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA
    J Affect Disord 121:165-8. 2010
    ..This study aims to examine the effects of depression and anxiety on health satisfaction in veterans with PTSD...
  20. pmc Exploring dissociation and oxytocin as pathways between trauma exposure and trauma-related hyperemesis gravidarum: a test-of-concept pilot
    Julia Seng
    Department of Obstetrics and Gynecology, School of Nursing, University of Michigan, Ann Arbor, MI, USA
    J Trauma Dissociation 14:40-55. 2013
    ..A linear regression model indicated that the independent association of the trauma-related HG subtype with oxytocin level was mediated by high levels of dissociative symptoms...
  21. pmc Cannabinoid facilitation of fear extinction memory recall in humans
    Christine A Rabinak
    Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
    Neuropharmacology 64:396-402. 2013
    ..This article is part of a Special Issue entitled 'Cognitive Enhancers'...
  22. pmc Exploring posttraumatic stress disorder symptom profile among pregnant women
    Julia S Seng
    Institute for Research on Women and Gender, University of Michigan, Ann Arbor 48109 1290, USA
    J Psychosom Obstet Gynaecol 31:176-87. 2010
    ..Further elucidation is warranted, including identifying triggers and determining if there are needs for pregnancy-specific interventions...
  23. pmc Self-related neural response to tailored smoking-cessation messages predicts quitting
    Hannah Faye Chua
    Health Behavior and Health Education, University of Michigan, Ann Arbor, Michigan, USA
    Nat Neurosci 14:426-7. 2011
    ..We found that increases in activation in self-related processing regions, particularly dorsomedial prefrontal cortex, to tailored messages predicted quitting during a 4-month follow-up...
  24. ncbi request reprint Cognitive modulation of the endocrine stress response to a pharmacological challenge in normal and panic disorder subjects
    James L Abelson
    Department of Psychiatry and Mental Health Research Institute, Trauma, Stress and Anxiety Research Group, University of Michigan, Ann Arbor 48109 0118, USA
    Arch Gen Psychiatry 62:668-75. 2005
    ..Scientific study of how such factors moderate human HPA axis activity has been limited. Their relevance to HPA axis disturbances in psychiatric patients is largely unexplored...
  25. ncbi request reprint Neural response to emotional salience in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 30:984-95. 2005
    ..Reduced modulation of visual cortex by emotionally salient stimuli also suggests a failure to organize cerebral activity at a global level...
  26. pmc Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder
    Rebecca K Sripada
    Department of Psychology and Psychiatry, University of Michigan, Ann Arbor, MI, USA
    J Psychiatry Neurosci 37:241-9. 2012
    ..However, few studies have examined patterns of connectivity at rest in individuals with PTSD, a potentially powerful method for illuminating brain network structure...
  27. doi request reprint Unconditioned freezing is enhanced in an appetitive context: implications for the contextual dependency of unconditioned fear
    Dayan Knox
    Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI 48105, USA
    Neurobiol Learn Mem 97:386-92. 2012
    ..Context-related expectancy mismatch may explain the enhancement of unconditioned fear expression seen in this study and warrants further examination...
  28. ncbi request reprint HPA axis activity in patients with panic disorder: review and synthesis of four studies
    James L Abelson
    Department of Psychiatry and Molecular and Behavioral Neuroscience Institute, Trauma, Stress and Anxiety Research Group, University of Michigan, Ann Arbor, Michigan 48109 0118, USA
    Depress Anxiety 24:66-76. 2007
    ..Most of the published panic/HPA literature is consistent with the hypothesis that HPA axis dysregulation in panic is due to hypersensitivity to contextual cues. This hypothesis requires experimental testing...
  29. ncbi request reprint Activation of the medial prefrontal cortex and extended amygdala by individual ratings of emotional arousal: a fMRI study
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 0118, USA
    Biol Psychiatry 53:211-5. 2003
    ....
  30. ncbi request reprint Facial expressions and complex IAPS pictures: common and differential networks
    Jennifer C Britton
    Department of Neuroscience, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 31:906-19. 2006
    ..For the most part, these regions were activated in response to all specific emotions; however, some regions responded only to a subset...
  31. ncbi request reprint Habituation of rostral anterior cingulate cortex to repeated emotionally salient pictures
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Ann Arbor, MI, USA
    Neuropsychopharmacology 28:1344-50. 2003
    ..These findings highlight the phasic activity of the rACC in emotional processing consistent with habituation...
  32. doi request reprint The impact of panic disorder on interoception and dyspnea reports in chronic obstructive pulmonary disease
    Nicholas D Giardino
    Mental Health Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
    Biol Psychol 84:142-6. 2010
    ..Emotional responses to dyspneic sensations may account for higher dyspnea ratings in patients with PD and COPD...
  33. pmc Neural activation to emotional faces in adolescents with autism spectrum disorders
    Shih Jen Weng
    Department of Psychology, University of Michigan, USA Neuroscience Program, University of Michigan, USA
    J Child Psychol Psychiatry 52:296-305. 2011
    ....
  34. pmc Preliminary evidence of white matter abnormality in the uncinate fasciculus in generalized social anxiety disorder
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48105, USA
    Biol Psychiatry 66:691-4. 2009
    ..The goal of this study was to investigate brain frontal WM abnormalities using diffusion tensor imaging (DTI) in patients with social anxiety disorder...
  35. doi request reprint The neural correlates of intertemporal decision-making: contributions of subjective value, stimulus type, and trait impulsivity
    Chandra Sekhar Sripada
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 2700, USA
    Hum Brain Mapp 32:1637-48. 2011
    ..These findings significantly advance our understanding of the specificity and overlap of functions subserved by different regions involved in intertemporal decision-making, and help to reconcile conflicting accounts in the literature...
  36. doi request reprint Potentially modifiable pre-, peri-, and postdeployment characteristics associated with deployment-related posttraumatic stress disorder among ohio army national guard soldiers
    Emily Goldmann
    Columbia University, New York, NY 10032, USA
    Ann Epidemiol 22:71-8. 2012
    ..To evaluate potentially modifiable deployment characteristics-- predeployment preparedness, unit support during deployment, and postdeployment support-that may be associated with deployment-related posttraumatic stress disorder (PTSD)...
  37. pmc A multiple-plane approach to measure the structural properties of functionally active regions in the human cortex
    Xin Wang
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 49:3075-85. 2010
    ..These results support the use of novel approaches for combined analysis of functional and structural neuroimaging...
  38. ncbi request reprint Medial frontal cortex activity and loss-related responses to errors
    Stephan F Taylor
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Neurosci 26:4063-70. 2006
    ..The findings support the hypothesis that the rostral extent of the MFC (rACC) processes loss-related responses to errors, and individual differences may account for some of the reported variation of error-related foci in the MFC...
  39. ncbi request reprint Cerebrospinal fluid corticotropin-releasing factor concentration is associated with pain but not fatigue symptoms in patients with fibromyalgia
    Samuel A McLean
    Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
    Neuropsychopharmacology 31:2776-82. 2006
    ..Further studies are needed to better understand the nature of the association between CSF CRF and pain symptoms in FM...
  40. doi request reprint Neurocircuits underlying cognition-emotion interaction in a social decision making context
    S Shaun Ho
    Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
    Neuroimage 63:843-57. 2012
    ..These results identify brain pathways through which emotion shapes subjective values in a social DM context...
  41. pmc Single prolonged stress disrupts retention of extinguished fear in rats
    Dayan Knox
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    Learn Mem 19:43-9. 2012
    ..The results demonstrate that SPS disrupts extinction retention, leading to enhanced fear renewal; further research is needed to identify the neurobiological processes through which SPS induces these effects...
  42. ncbi request reprint A functional anatomic study of emotion in schizophrenia
    Stephan F Taylor
    Department of Psychiatry, University of Michigan Medical Center, UH 9D Box 0118, 1500 E Medical Center Drive, Ann Arbor MI 48109 0118, USA
    Schizophr Res 58:159-72. 2002
    ..Overall, the data are consistent with a general failure to process salient stimuli in schizophrenia, and the findings support the involvement of the amygdala in the positive symptoms of schizophrenia...
  43. pmc Prevalence, trauma history, and risk for posttraumatic stress disorder among nulliparous women in maternity care
    Julia S Seng
    University of Michigan Institute for Research on Women and Gender, School of Nursing, Department of Women s Studies, Ann Arbor, Michigan 48109 1290, USA
    Obstet Gynecol 114:839-47. 2009
    ....
  44. ncbi request reprint Error-related hyperactivity of the anterior cingulate cortex in obsessive-compulsive disorder
    Kate Dimond Fitzgerald
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, 48109 0118, USA
    Biol Psychiatry 57:287-94. 2005
    ..In this functional magnetic resonance imaging (fMRI) study, we sought to further localize error-processing differences within the ACC of OCD patients compared with healthy subjects...
  45. pmc 'Do I like this person?' A network analysis of midline cortex during a social preference task
    Ashley C Chen
    Neuroscience Program, University of Michigan, USA
    Neuroimage 51:930-9. 2010
    ....
  46. ncbi request reprint Effect of repeat exposure on neuroendocrine and symptom responses to pentagastrin
    Samir Khan
    Trauma, Stress and Anxiety Research Group, Department of Psychiatry, University of Michigan, UH 9D 0118, 1500 E Medical Center Drive, Ann Arbor, MI 4810 0118, USA
    Psychiatry Res 126:189-95. 2004
    ..Novelty, per se, is not likely the primary mediator of the HPA response. This model may be useful for further study of cognitive-emotional modulators of HPA axis activity...
  47. ncbi request reprint Effects of propranolol on symptom and endocrine responses to pentagastrin
    Samir Khan
    Trauma, Stress and Anxiety Research Center, Department of Psychiatry, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109 0118, USA
    Psychoneuroendocrinology 29:1163-71. 2004
    ..They support the hypothesis that the HPA response to pentagastrin is not secondary to the psychological stress of its side effects...
  48. doi request reprint Pilot study of response inhibition and error processing in the posterior medial prefrontal cortex in healthy youth
    Kate Dimond Fitzgerald
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
    J Child Psychol Psychiatry 49:986-94. 2008
    ..Developmental neuroimaging studies of response inhibition have found pMFC activation, but the possible contribution of error-related activation during inhibitory processing has not been well studied in youth...
  49. pmc Neural correlates of message tailoring and self-relatedness in smoking cessation programming
    Hannah Faye Chua
    Department of Health Behavior and Health Education, University of Michigan, 300 North Ingalls Street, Ann Arbor, MI 48109 0471, USA
    Biol Psychiatry 65:165-8. 2009
    ..However, little is known about the brain responses of smokers when they receive tailored smoking cessation messages...
  50. ncbi request reprint Valence, gender, and lateralization of functional brain anatomy in emotion: a meta-analysis of findings from neuroimaging
    Tor D Wager
    Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 19:513-31. 2003
    ..The study provides evidence that lateralization of emotional activity is more complex and region-specific than predicted by previous theories of emotion and the brain...
  51. pmc Assessing the neuroendocrine stress response in the functional neuroimaging context
    Anthony P King
    Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
    Neuroimage 47:1116-24. 2009
    ..g. hormone responses as between-subject regressors of BOLD activations, hormone levels as within-subject regressors in analyses of covariance of brain activity over time, etc.)...
  52. pmc Functional neuroimaging of mentalizing during the trust game in social anxiety disorder
    Chandra Sehkar Sripada
    Psychiatry Affective Neuroimaging Laboratory, Department of Psychiatry, University of Michigan, MI 48109 2700, USA
    Neuroreport 20:984-9. 2009
    ..Diminished medial prefrontal cortex function may play a role in the social-cognitive pathophysiology of social anxiety...
  53. pmc DHEA Enhances Emotion Regulation Neurocircuits and Modulates Memory for Emotional Stimuli
    Rebecca K Sripada
    1 Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA 2 Department of Psychology, University of Michigan, Ann Arbor, MI, USA
    Neuropsychopharmacology 38:1798-807. 2013
    ....
  54. doi request reprint A pilot study of group mindfulness-based cognitive therapy (MBCT) for combat veterans with posttraumatic stress disorder (PTSD)
    Anthony P King
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48105, USA
    Depress Anxiety 30:638-45. 2013
    ..This study investigated the feasibility, acceptability, and clinical outcomes of an MBCT group intervention adapted for combat posttraumatic stress disorder (PTSD)...
  55. pmc Childhood abuse history, posttraumatic stress disorder, postpartum mental health, and bonding: a prospective cohort study
    Julia S Seng
    Institute for Research onWomen and Gender, University of Michigan, Ann Arbor, Michigan 48109 1290, USA
    J Midwifery Womens Health 58:57-68. 2013
    ..This prospective study included 566 nulliparous women in 3 cohorts: PTSD-positive, trauma-exposed resilient, and not exposed to trauma...
  56. pmc Exogenous glucocorticoids decrease subgenual cingulate activity evoked by sadness
    Keith D Sudheimer
    1 Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA 2 Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA
    Neuropsychopharmacology 38:826-45. 2013
    ....
  57. doi request reprint Decision-related loss: regret and disappointment
    Hannah Faye Chua
    Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
    Neuroimage 47:2031-40. 2009
    ....
  58. ncbi request reprint Brain-imaging studies of posttraumatic stress disorder
    Israel Liberzon
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
    CNS Spectr 8:641-50. 2003
    ..This article reviews the literature on structural, functional, and neurochemical brain-imaging studies of PTSD...
  59. ncbi request reprint Neuroticism associated with neural activation patterns to positive stimuli
    Jennifer C Britton
    Department of Neuroscience, University of Michigan, Ann Arbor, MI, USA
    Psychiatry Res 156:263-7. 2007
    ..Neuroticism directly correlated with dorsomedial prefrontal cortex activation in response to positive stimuli. Dorsomedial prefrontal cortex correlations may reflect increased self-association in individuals with high neuroticism...
  60. pmc Naturalistic stress and cortisol response to awakening: adaptation to seafaring
    Jonathan Liberzon
    University of Michigan School of Natural Resources, Department of Psychiatry, Ann Arbor, MI 48103, USA
    Psychoneuroendocrinology 33:1023-6. 2008
    ....
  61. pmc Distributed effects of methylphenidate on the network structure of the resting brain: A connectomic pattern classification analysis
    Chandra Sekhar Sripada
    Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA Electronic address
    Neuroimage 81:213-21. 2013
    ..These results suggest that connectivity changes within and between large-scale networks are potentially involved in the mechanisms by which methylphenidate improves attention functioning. ..
  62. ncbi request reprint Nonstationary cluster-size inference with random field and permutation methods
    Satoru Hayasaka
    Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Neuroimage 22:676-87. 2004
    ..We include a detailed and consolidated description of Worsley nonstationary RFT cluster-size test...
  63. ncbi request reprint Neural correlates of emotion regulation in psychopathology
    Stephan F Taylor
    University of Michigan Department of Psychiatry, 4250 Plymouth Rd, Ann Arbor, MI 48109 5765, USA
    Trends Cogn Sci 11:413-8. 2007
    ..We summarize recent research to suggest that networks of direct and indirect pathways exist by which cognition can regulate pathological emotion, and the inter-relationships of specific nodes within the networks need to be characterized...
  64. ncbi request reprint Service use data analysis of pre-pregnancy psychiatric and somatic diagnoses in women with hyperemesis gravidarum
    Julia S Seng
    Institute for Research on Women and Gender, Department of Obstetrics and Gynecology, School of Nursing, University of Michigan, Ann Arbor, MI 48109 1290, USA
    J Psychosom Obstet Gynaecol 28:209-17. 2007
    ....
  65. ncbi request reprint The development of persistent pain and psychological morbidity after motor vehicle collision: integrating the potential role of stress response systems into a biopsychosocial model
    Samuel A McLean
    Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Psychosom Med 67:783-90. 2005
    ....
  66. ncbi request reprint Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI
    K Luan Phan
    Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
    Neuroimage 16:331-48. 2002
    ..This review provides a critical comparison of findings across individual studies and suggests that separate brain regions are involved in different aspects of emotion...
  67. pmc Single prolonged stress decreases glutamate, glutamine, and creatine concentrations in the rat medial prefrontal cortex
    Dayan Knox
    Department of Psychiatry, University of Michigan, Ann Arbor, MI, United States
    Neurosci Lett 480:16-20. 2010
    ..SPS did not alter the neurochemical profiles of either the hippocampus or amygdala. These data suggest that SPS selectively attenuates excitatory tone, without a disruption of neuronal integrity, in the mPFC...
  68. pmc Cognitive modulation of endocrine responses to CRH stimulation in healthy subjects
    James L Abelson
    University of Michigan Department of Psychiatry, Trauma, Stress and Anxiety Research Group, Molecular and Behavioral Neuroscience Institute, United States
    Psychoneuroendocrinology 35:451-9. 2010
    ....
  69. pmc Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional study
    Nicholas D Giardino
    Mental Health Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
    Respir Res 11:29. 2010
    ..The purpose of this study is to determine whether there is an association between anxiety and functional measures, quality of life and dyspnea...
  70. doi request reprint Inactivation of the prelimbic cortex enhances freezing induced by trimethylthiazoline, a component of fox feces
    Christopher J Fitzpatrick
    Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI 48105, USA
    Behav Brain Res 221:320-3. 2011
    ..Further research is needed to define the parameters under which the PL inhibits unconditioned defense behavior...
  71. doi request reprint Prolonged exposure for PTSD in a Veterans Health Administration PTSD clinic
    Sheila A M Rauch
    Mental Health Service, Veterans Administration Ann Arbor Healthcare System and Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
    J Trauma Stress 22:60-4. 2009
    ..In addition, veterans demonstrated significant reductions in depression from pre- to posttreatment. In conclusion, PE is effective in reducing the symptoms of PTSD in veterans...
  72. ncbi request reprint Cortisol level and perinatal outcome in pregnant women with posttraumatic stress disorder: a pilot study
    Julia S Seng
    Institute for Research on Womens and Gender, School of Nursing, University of Michigan, Ann Arbor, Michigan 48109 1290, USA
    J Midwifery Womens Health 50:392-8. 2005
    ..This finding suggests that salivary cortisol would be a useful biological measure to include in perinatal research on PTSD and childbearing...
  73. doi request reprint PTSD comorbidity and suicidal ideation associated with PTSD within the Ohio Army National Guard
    Joseph R Calabrese
    Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Psychiatry 72:1072-8. 2011
    ..To study the relation between posttraumatic stress disorder (PTSD) psychiatric comorbidity and suicidal ideation in a representative sample of Ohio Army National Guard soldiers...
  74. pmc Ecological salivary cortisol analysis-- part 2: relative impact of trauma history, posttraumatic stress, comorbidity, chronic stress, and known confounds on hormone levels
    Anthony P King
    University of Michigan, Ann Arbor
    J Am Psychiatr Nurses Assoc 14:285-96. 2008
    ..Ecological sampling departs from laboratory study norms, with implications for analysis...
  75. ncbi request reprint Psychopharmacological treatment in PTSD: a critical review
    Ronald C Albucher
    Department of Psychiatry PCT 116C, Veterans Administration Medical Center, University of Michigan, 2215 Fuller Road, Ann Arbor, MI 481105, USA
    J Psychiatr Res 36:355-67. 2002
    ..This article reviews the existing research literature on pharmacological treatments for PTSD, identifies the most effective treatments, and where possible examines their mechanism of action with respect to the neurobiology of PTSD...
  76. ncbi request reprint Topiramate attenuates exaggerated acoustic startle in an animal model of PTSD
    Samir Khan
    Department of Psychiatry, University of Michigan, and VA Medical Center, Ann Arbor, USA
    Psychopharmacology (Berl) 172:225-9. 2004
    ..The anticonvulsant topiramate is an AMPA antagonist that also demonstrates potent anti-kindling effects and may, therefore, have promise in treating trauma-enhanced ASR...
  77. pmc Neural responses to elements of a web-based smoking cessation program
    Hannah Faye Chua
    University of Michigan, Ann Arbor, USA
    Stud Health Technol Inform 144:174-8. 2009
    ..This research is relevant for advancing web-based tailored interventions for substance use...
  78. ncbi request reprint Neural correlates of individual ratings of emotional salience: a trial-related fMRI study
    K Luan Phan
    Department of Psychiatry and Behvioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Neuroimage 21:768-80. 2004
    ..The findings highlight both overlapping and segregated neural representations of intrinsic value and personal relevance during the appraisal of emotional stimuli...
  79. ncbi request reprint Functional neuroimaging studies of human emotions
    K Luan Phan
    Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan 48201, USA
    CNS Spectr 9:258-66. 2004
    ..This paper will review observations in several regions of interest in limbic (eg, amygdala, anterior cingulate cortex) and paralimbic (eg, medial prefrontal cortex, insula) brain regions in emotional responding...
  80. doi request reprint Distinct processing of facial emotion of own-race versus other-race
    Kyoung Uk Lee
    Department of Psychiatry, The Catholic University of Korea, Seoul, Korea
    Neuroreport 19:1021-5. 2008
    ..Our findings provide evidence for differential processing of emotional faces as a function of race...

Research Grants2

  1. Cognition-Emotion-HPA Interaction: Translation Network
    Israel Liberzon; Fiscal Year: 2007
    ..It will provide a foundation for larger translational science projects and a context for training the translational scientists of the future. ..
  2. Mental Health Research Education Grant (R25)
    Israel Liberzon; Fiscal Year: 2007
    ..This program strives to foster the development of mental health researchers by providing the training, structure, and resources that are necessary to begin an academic, research-focused career in psychiatry. ..