Research Topics
Species | Israel LiberzonSummaryAffiliation: University of Michigan Country: USA Publications
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Publications
mu-Opioid receptors and limbic responses to aversive emotional stimuliIsrael Liberzon
Department of Psychiatry, Veterans Administration Medical Center, University of Michigan, Ann Arbor, MI 48105, USA
Proc Natl Acad Sci U S A 99:7084-9. 2002..This is consistent with an inhibitory/anxiolytic role of the endogenous opioid system in limbic regions of the temporal lobe and basal forebrain...
Neural correlates of traumatic recall in posttraumatic stress disorderIsrael Liberzon
Psychiatry Service, Ann Arbor Veterans Affairs Medical Center, MI 48109, USA
Stress 6:151-6. 2003....- Altered central micro-opioid receptor binding after psychological traumaIsrael Liberzon
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, Michigan 48109 0118, USA
Biol Psychiatry 61:1030-8. 2007..The mu-opioid neurotransmitter system, implicated in responses to stress and suppression of pain, is distributed in and is thought to regulate the function of brain regions that are implicated in affective processing... - The functional neuroanatomy of PTSD: a critical reviewIsrael Liberzon
Department of Psychiatry, University of Michigan, MCHC, F6135, Ann Arbor, MI 48109, USA
Prog Brain Res 167:151-69. 2008..It is proposed that the mPFC plays a role in the "contextualization" of stimuli, and dysregulation of contextualization processes might play a key role in the generation of PTSD symptoms... - Neuroimaging studies of emotional responses in PTSDIsrael Liberzon
Trauma Stress and Anxiety Research Group, Department of Psychiatry, Ann Arbor VA Healthcare System, University of Michigan, 1500 E Medical Center Drive UH9D 0118, Ann Arbor, MI 48109 0118, USA
Ann N Y Acad Sci 1071:87-109. 2006..Further links between functional neuroanatomy of emotional responses and neuroendocrine stress regulation are proposed... - Extended amygdala and emotional salience: a PET activation study of positive and negative affectIsrael Liberzon
Department of Psychiatry, University of Michigan, Ann Arbor, USA
Neuropsychopharmacology 28:726-33. 2003.... - Increased psychiatric morbidity after abdominal aortic surgery: risk factors for stress-related disordersIsrael Liberzon
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
J Vasc Surg 43:929-34. 2006..These complications are also expected after abdominal aortic surgery, but their incidence and relevant risk factors in this population have not been documented... - Paralimbic and medial prefrontal cortical involvement in neuroendocrine responses to traumatic stimuliIsrael Liberzon
Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
Am J Psychiatry 164:1250-8. 2007..The authors used [(15)O]H(2)O positron emission tomography (PET) on subjects with posttraumatic stress disorder (PTSD) to study these circuits... - Corticolimbic blood flow during nontraumatic emotional processing in posttraumatic stress disorderK Luan Phan
Department of Psychiatry, Pritzker School of Medicine, The University of Chicago, Chicago, Ill, USA
Arch Gen Psychiatry 63:184-92. 2006..Activation of the amygdala and lack of ventral MPFC deactivation to negatively valenced images in combat controls may reflect compensatory changes after trauma exposure that are not associated with PTSD... - Effects of perceived control and cognitive coping on endocrine stress responses to pharmacological activationJames L Abelson
Department of Psychiatry, Trauma, Stress and Anxiety Research Group, Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, Michigan, USA
Biol Psychiatry 64:701-7. 2008..This study attempted to identify the core factors that modulate HPA axis activity in this model... - Neural dysregulation in posttraumatic stress disorder: evidence for disrupted equilibrium between salience and default mode brain networksRebecca K Sripada
Departments of Psychology, University of Michigan, Ann Arbor, Michigan, USA
Psychosom Med 74:904-11. 2012..This might be linked to aberrations in large-scale networks subserving the detection of salient stimuli (i.e., the salience network [SN]) and stimulus-independent, internally focused thought (i.e., the default mode network [DMN])... - Corticolimbic blood flow in posttraumatic stress disorder during script-driven imageryJennifer C Britton
Neuroscience Program, University of Michigan, Michigan, USA
Biol Psychiatry 57:832-40. 2005..CONCLUSIONS: Trauma-specific patterns may represent potential compensatory changes to traumatic reminders, while patterns observed only in the PTSD group may reflect neural substrates specific to PTSD pathophysiology... - Subjective rating of emotionally salient stimuli modulates neural activityStephan F Taylor
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
Neuroimage 18:650-9. 2003..For both RTNG and PSVW, subjects activated the left fusiform gyrus. The results support the proposition that task instructions about how subjects should process evocative stimuli can affect neural activity... 
Trait anxiety modulates anterior cingulate activation to threat interferenceHeide Klumpp
Department of Psychiatry, University of Michigan Ann Arbor, 4250 Plymouth Road, Ann Arbor, MI 48109, USA
Depress Anxiety 28:194-201. 2011..anterior cingulate cortex, "ACC") might play a role. In this study, we explored the hypothesis that trait anxiety would be associated with ACC activity in an attentional control task with varying levels of threat interference...- Medial prefrontal cortex and right insula activity predict plasma ACTH response to trauma recallAnthony P King
Psychiatry, University of Michigan, Ann Arbor, MI, USA
Neuroimage 47:872-80. 2009..These results support the hypotheses that right insula is involved in psychological activation of the LHPA axis and that rostral mPFC may negatively modulate LHPA axis responses... - Social appraisal in chronic psychosis: role of medial frontal and occipital networksStephan F Taylor
Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Rd, Ann Arbor MI 48109 2700, USA
J Psychiatr Res 45:526-38. 2011.... - Medial frontal hyperactivity in reality distortionStephan F Taylor
Department of Psychiatry, University of Michigan Medical Center, Ann Arbor, Michigan 48109 5765, USA
Biol Psychiatry 61:1171-8. 2007..The amygdala interacts with MPFC, also carries out socioemotional processing, and has been implicated in schizophrenia; thus, we also tested the hypothesis that patients would exhibit aberrant amygdala activity... - Relationship between anxiety, depression, and health satisfaction among veterans with PTSDSheila A M Rauch
VA Ann Arbor Healthcare System, Ann Arbor, MI 48105, USA
J Affect Disord 121:165-8. 2010..This study aims to examine the effects of depression and anxiety on health satisfaction in veterans with PTSD... - Cannabinoid facilitation of fear extinction memory recall in humansChristine A Rabinak
Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
Neuropharmacology 64:396-402. 2013..This article is part of a Special Issue entitled 'Cognitive Enhancers'... - Exploring posttraumatic stress disorder symptom profile among pregnant womenJulia S Seng
Institute for Research on Women and Gender, University of Michigan, Ann Arbor 48109 1290, USA
J Psychosom Obstet Gynaecol 31:176-87. 2010..Further elucidation is warranted, including identifying triggers and determining if there are needs for pregnancy-specific interventions... - Cognitive modulation of the endocrine stress response to a pharmacological challenge in normal and panic disorder subjectsJames L Abelson
Department of Psychiatry and Mental Health Research Institute, Trauma, Stress and Anxiety Research Group, University of Michigan, Ann Arbor 48109 0118, USA
Arch Gen Psychiatry 62:668-75. 2005..Scientific study of how such factors moderate human HPA axis activity has been limited. Their relevance to HPA axis disturbances in psychiatric patients is largely unexplored... - Neural response to emotional salience in schizophreniaStephan F Taylor
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
Neuropsychopharmacology 30:984-95. 2005..Reduced modulation of visual cortex by emotionally salient stimuli also suggests a failure to organize cerebral activity at a global level... - Self-related neural response to tailored smoking-cessation messages predicts quittingHannah Faye Chua
Health Behavior and Health Education, University of Michigan, Ann Arbor, Michigan, USA
Nat Neurosci 14:426-7. 2011..We found that increases in activation in self-related processing regions, particularly dorsomedial prefrontal cortex, to tailored messages predicted quitting during a 4-month follow-up... - Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorderRebecca K Sripada
Department of Psychology and Psychiatry, University of Michigan, Ann Arbor, MI, USA
J Psychiatry Neurosci 37:241-9. 2012..However, few studies have examined patterns of connectivity at rest in individuals with PTSD, a potentially powerful method for illuminating brain network structure... - Unconditioned freezing is enhanced in an appetitive context: implications for the contextual dependency of unconditioned fearDayan Knox
Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI 48105, USA
Neurobiol Learn Mem 97:386-92. 2012..Context-related expectancy mismatch may explain the enhancement of unconditioned fear expression seen in this study and warrants further examination... - Habituation of rostral anterior cingulate cortex to repeated emotionally salient picturesK Luan Phan
Department of Psychiatry, University of Michigan, Ann Arbor, Ann Arbor, MI, USA
Neuropsychopharmacology 28:1344-50. 2003..These findings highlight the phasic activity of the rACC in emotional processing consistent with habituation... - The impact of panic disorder on interoception and dyspnea reports in chronic obstructive pulmonary diseaseNicholas D Giardino
Mental Health Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
Biol Psychol 84:142-6. 2010..Emotional responses to dyspneic sensations may account for higher dyspnea ratings in patients with PD and COPD... - Activation of the medial prefrontal cortex and extended amygdala by individual ratings of emotional arousal: a fMRI studyK Luan Phan
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109-0118, USA
Biol Psychiatry 53:211-5. 2003..CONCLUSIONS: Our findings demonstrate that individual behavioral data are useful in improving detection of activation in block-design functional imaging studies... - HPA axis activity in patients with panic disorder: review and synthesis of four studiesJames L Abelson
Department of Psychiatry and Molecular and Behavioral Neuroscience Institute, Trauma, Stress and Anxiety Research Group, University of Michigan, Ann Arbor, Michigan 48109 0118, USA
Depress Anxiety 24:66-76. 2007..Most of the published panic/HPA literature is consistent with the hypothesis that HPA axis dysregulation in panic is due to hypersensitivity to contextual cues. This hypothesis requires experimental testing... - Facial expressions and complex IAPS pictures: common and differential networksJennifer C Britton
Department of Neuroscience, University of Michigan, Ann Arbor, MI 48109, USA
Neuroimage 31:906-19. 2006..For the most part, these regions were activated in response to all specific emotions; however, some regions responded only to a subset... - Preliminary evidence of white matter abnormality in the uncinate fasciculus in generalized social anxiety disorderK Luan Phan
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48105, USA
Biol Psychiatry 66:691-4. 2009..The goal of this study was to investigate brain frontal WM abnormalities using diffusion tensor imaging (DTI) in patients with social anxiety disorder... - Neural activation to emotional faces in adolescents with autism spectrum disordersShih Jen Weng
Department of Psychology, University of Michigan, USA Neuroscience Program, University of Michigan, USA
J Child Psychol Psychiatry 52:296-305. 2011.... - A multiple-plane approach to measure the structural properties of functionally active regions in the human cortexXin Wang
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
Neuroimage 49:3075-85. 2010..These results support the use of novel approaches for combined analysis of functional and structural neuroimaging... - Potentially modifiable pre-, peri-, and postdeployment characteristics associated with deployment-related posttraumatic stress disorder among ohio army national guard soldiersEmily Goldmann
Columbia University, New York, NY 10032, USA
Ann Epidemiol 22:71-8. 2012..To evaluate potentially modifiable deployment characteristics-- predeployment preparedness, unit support during deployment, and postdeployment support-that may be associated with deployment-related posttraumatic stress disorder (PTSD)... - Medial frontal cortex activity and loss-related responses to errorsStephan F Taylor
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
J Neurosci 26:4063-70. 2006..The findings support the hypothesis that the rostral extent of the MFC (rACC) processes loss-related responses to errors, and individual differences may account for some of the reported variation of error-related foci in the MFC... - Cerebrospinal fluid corticotropin-releasing factor concentration is associated with pain but not fatigue symptoms in patients with fibromyalgiaSamuel A McLean
Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
Neuropsychopharmacology 31:2776-82. 2006..Further studies are needed to better understand the nature of the association between CSF CRF and pain symptoms in FM... - The neural correlates of intertemporal decision-making: contributions of subjective value, stimulus type, and trait impulsivityChandra Sekhar Sripada
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109 2700, USA
Hum Brain Mapp 32:1637-48. 2011..These findings significantly advance our understanding of the specificity and overlap of functions subserved by different regions involved in intertemporal decision-making, and help to reconcile conflicting accounts in the literature... - Single prolonged stress disrupts retention of extinguished fear in ratsDayan Knox
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
Learn Mem 19:43-9. 2012..The results demonstrate that SPS disrupts extinction retention, leading to enhanced fear renewal; further research is needed to identify the neurobiological processes through which SPS induces these effects... - 'Do I like this person?' A network analysis of midline cortex during a social preference taskAshley C Chen
Neuroscience Program, University of Michigan, USA
Neuroimage 51:930-9. 2010.... - Effect of repeat exposure on neuroendocrine and symptom responses to pentagastrinSamir Khan
Trauma, Stress and Anxiety Research Group, Department of Psychiatry, University of Michigan, UH 9D/0118, 1500 E. Medical Center Drive, Ann Arbor, MI 4810-0118, USA
Psychiatry Res 126:189-95. 2004..Novelty, per se, is not likely the primary mediator of the HPA response. This model may be useful for further study of cognitive-emotional modulators of HPA axis activity... - Prevalence, trauma history, and risk for posttraumatic stress disorder among nulliparous women in maternity careJulia S Seng
University of Michigan Institute for Research on Women and Gender, School of Nursing, Department of Women s Studies, Ann Arbor, Michigan 48109 1290, USA
Obstet Gynecol 114:839-47. 2009.... - A functional anatomic study of emotion in schizophreniaStephan F Taylor
Department of Psychiatry, University of Michigan Medical Center, UH 9D Box 0118, 1500 E Medical Center Drive, Ann Arbor MI 48109 0118, USA
Schizophr Res 58:159-72. 2002..Overall, the data are consistent with a general failure to process salient stimuli in schizophrenia, and the findings support the involvement of the amygdala in the positive symptoms of schizophrenia... - Error-related hyperactivity of the anterior cingulate cortex in obsessive-compulsive disorderKate Dimond Fitzgerald
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, 48109-0118, USA
Biol Psychiatry 57:287-94. 2005..Activity in this region was positively correlated with symptom severity in the patients. CONCLUSIONS: Error-processing abnormalities within the rostral anterior cingulate occur in the absence of symptom expression in patients with OCD... - Effects of propranolol on symptom and endocrine responses to pentagastrinSamir Khan
Trauma, Stress and Anxiety Research Center, Department of Psychiatry, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0118, USA
Psychoneuroendocrinology 29:1163-71. 2004..They support the hypothesis that the HPA response to pentagastrin is not secondary to the psychological stress of its side effects... - Functional neuroimaging of mentalizing during the trust game in social anxiety disorderChandra Sehkar Sripada
Psychiatry Affective Neuroimaging Laboratory, Department of Psychiatry, University of Michigan, MI 48109 2700, USA
Neuroreport 20:984-9. 2009..Diminished medial prefrontal cortex function may play a role in the social-cognitive pathophysiology of social anxiety... - Assessing the neuroendocrine stress response in the functional neuroimaging contextAnthony P King
Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
Neuroimage 47:1116-24. 2009..g. hormone responses as between-subject regressors of BOLD activations, hormone levels as within-subject regressors in analyses of covariance of brain activity over time, etc.)... - Neural correlates of message tailoring and self-relatedness in smoking cessation programmingHannah Faye Chua
Department of Health Behavior and Health Education, University of Michigan, 300 North Ingalls Street, Ann Arbor, MI 48109 0471, USA
Biol Psychiatry 65:165-8. 2009..However, little is known about the brain responses of smokers when they receive tailored smoking cessation messages... - Valence, gender, and lateralization of functional brain anatomy in emotion: a meta-analysis of findings from neuroimagingTor D Wager
Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
Neuroimage 19:513-31. 2003..The study provides evidence that lateralization of emotional activity is more complex and region-specific than predicted by previous theories of emotion and the brain... - Pilot study of response inhibition and error processing in the posterior medial prefrontal cortex in healthy youthKate Dimond Fitzgerald
Department of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA
J Child Psychol Psychiatry 49:986-94. 2008..Developmental neuroimaging studies of response inhibition have found pMFC activation, but the possible contribution of error-related activation during inhibitory processing has not been well studied in youth... - Exogenous glucocorticoids decrease subgenual cingulate activity evoked by sadnessKeith D Sudheimer
Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
Neuropsychopharmacology 38:826-45. 2013.... - Childhood abuse history, posttraumatic stress disorder, postpartum mental health, and bonding: a prospective cohort studyJulia S Seng
Institute for Research onWomen and Gender, University of Michigan, Ann Arbor, Michigan 48109 1290, USA
J Midwifery Womens Health 58:57-68. 2013..This prospective study included 566 nulliparous women in 3 cohorts: PTSD-positive, trauma-exposed resilient, and not exposed to trauma... - Neuroticism associated with neural activation patterns to positive stimuliJennifer C Britton
Department of Neuroscience, University of Michigan, Ann Arbor, MI, USA
Psychiatry Res 156:263-7. 2007..Neuroticism directly correlated with dorsomedial prefrontal cortex activation in response to positive stimuli. Dorsomedial prefrontal cortex correlations may reflect increased self-association in individuals with high neuroticism... - Brain-imaging studies of posttraumatic stress disorderIsrael Liberzon
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA
CNS Spectr 8:641-50. 2003..This article reviews the literature on structural, functional, and neurochemical brain-imaging studies of PTSD... - Naturalistic stress and cortisol response to awakening: adaptation to seafaringJonathan Liberzon
University of Michigan School of Natural Resources, Department of Psychiatry, Ann Arbor, MI 48103, USA
Psychoneuroendocrinology 33:1023-6. 2008.... - Decision-related loss: regret and disappointmentHannah Faye Chua
Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA
Neuroimage 47:2031-40. 2009.... - Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRIK Luan Phan
Department of Psychiatry, University of Michigan, Ann Arbor, Michigan 48109, USA
Neuroimage 16:331-48. 2002..This review provides a critical comparison of findings across individual studies and suggests that separate brain regions are involved in different aspects of emotion... - Nonstationary cluster-size inference with random field and permutation methodsSatoru Hayasaka
Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109-2029, USA
Neuroimage 22:676-87. 2004..We include a detailed and consolidated description of Worsley nonstationary RFT cluster-size test... - The development of persistent pain and psychological morbidity after motor vehicle collision: integrating the potential role of stress response systems into a biopsychosocial modelSamuel A McLean
Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Psychosom Med 67:783-90. 2005.... - Service use data analysis of pre-pregnancy psychiatric and somatic diagnoses in women with hyperemesis gravidarumJulia S Seng
Institute for Research on Women and Gender, Department of Obstetrics and Gynecology, School of Nursing, University of Michigan, Ann Arbor, MI 48109 1290, USA
J Psychosom Obstet Gynaecol 28:209-17. 2007.... - Single prolonged stress decreases glutamate, glutamine, and creatine concentrations in the rat medial prefrontal cortexDayan Knox
Department of Psychiatry, University of Michigan, Ann Arbor, MI, United States
Neurosci Lett 480:16-20. 2010..SPS did not alter the neurochemical profiles of either the hippocampus or amygdala. These data suggest that SPS selectively attenuates excitatory tone, without a disruption of neuronal integrity, in the mPFC... - Neural correlates of emotion regulation in psychopathologyStephan F Taylor
University of Michigan Department of Psychiatry, 4250 Plymouth Rd, Ann Arbor, MI 48109 5765, USA
Trends Cogn Sci 11:413-8. 2007..We summarize recent research to suggest that networks of direct and indirect pathways exist by which cognition can regulate pathological emotion, and the inter-relationships of specific nodes within the networks need to be characterized... - Cognitive modulation of endocrine responses to CRH stimulation in healthy subjectsJames L Abelson
University of Michigan Department of Psychiatry, Trauma, Stress and Anxiety Research Group, Molecular and Behavioral Neuroscience Institute, United States
Psychoneuroendocrinology 35:451-9. 2010.... - Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional studyNicholas D Giardino
Mental Health Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
Respir Res 11:29. 2010..The purpose of this study is to determine whether there is an association between anxiety and functional measures, quality of life and dyspnea... - Prolonged exposure for PTSD in a Veterans Health Administration PTSD clinicSheila A M Rauch
Mental Health Service, Veterans Administration Ann Arbor Healthcare System and Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA
J Trauma Stress 22:60-4. 2009..In addition, veterans demonstrated significant reductions in depression from pre- to posttreatment. In conclusion, PE is effective in reducing the symptoms of PTSD in veterans... - Ecological salivary cortisol analysis-- part 2: relative impact of trauma history, posttraumatic stress, comorbidity, chronic stress, and known confounds on hormone levelsAnthony P King
University of Michigan, Ann Arbor
J Am Psychiatr Nurses Assoc 14:285-96. 2008..Ecological sampling departs from laboratory study norms, with implications for analysis... - PTSD comorbidity and suicidal ideation associated with PTSD within the Ohio Army National GuardJoseph R Calabrese
Department of Psychiatry, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA
J Clin Psychiatry 72:1072-8. 2011..To study the relation between posttraumatic stress disorder (PTSD) psychiatric comorbidity and suicidal ideation in a representative sample of Ohio Army National Guard soldiers... - Inactivation of the prelimbic cortex enhances freezing induced by trimethylthiazoline, a component of fox fecesChristopher J Fitzpatrick
Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI 48105, USA
Behav Brain Res 221:320-3. 2011..Further research is needed to define the parameters under which the PL inhibits unconditioned defense behavior... - Cortisol level and perinatal outcome in pregnant women with posttraumatic stress disorder: a pilot studyJulia S Seng
Institute for Research on Womens and Gender, School of Nursing, University of Michigan, Ann Arbor, Michigan 48109 1290, USA
J Midwifery Womens Health 50:392-8. 2005..This finding suggests that salivary cortisol would be a useful biological measure to include in perinatal research on PTSD and childbearing... - Psychopharmacological treatment in PTSD: a critical reviewRonald C Albucher
Department of Psychiatry/PCT 116C, Veterans Administration Medical Center, University of Michigan, 2215 Fuller Road, Ann Arbor, MI 481105, USA
J Psychiatr Res 36:355-67. 2002..DISCUSSION: There is clear evidence for effective pharmacotherapy of PTSD. Future improvements in the treatment of this disorder await further clinical trials and neurobiological research... - Topiramate attenuates exaggerated acoustic startle in an animal model of PTSDSamir Khan
Department of Psychiatry, University of Michigan, and VA Medical Center, Ann Arbor, USA
Psychopharmacology (Berl) 172:225-9. 2004..In addition, topiramate demonstrates promise in treating exaggerated acoustic startle symptoms in PTSD or other stress-related disorders... - Neural responses to elements of a web-based smoking cessation programHannah Faye Chua
University of Michigan, Ann Arbor, USA
Stud Health Technol Inform 144:174-8. 2009..This research is relevant for advancing web-based tailored interventions for substance use... - Neural correlates of individual ratings of emotional salience: a trial-related fMRI studyK Luan Phan
Department of Psychiatry and Behvioral Neuroscience, Wayne State University School of Medicine, Detroit, MI 48201, USA
Neuroimage 21:768-80. 2004..The findings highlight both overlapping and segregated neural representations of intrinsic value and personal relevance during the appraisal of emotional stimuli... - Distinct processing of facial emotion of own-race versus other-raceKyoung Uk Lee
Department of Psychiatry, The Catholic University of Korea, Seoul, Korea
Neuroreport 19:1021-5. 2008..Our findings provide evidence for differential processing of emotional faces as a function of race... - Functional neuroimaging studies of human emotionsK Luan Phan
Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan 48201, USA
CNS Spectr 9:258-66. 2004..This paper will review observations in several regions of interest in limbic (eg, amygdala, anterior cingulate cortex) and paralimbic (eg, medial prefrontal cortex, insula) brain regions in emotional responding...
Research Grants
- Cognition-Emotion-HPA Interaction: Translation NetworkIsrael Liberzon; Fiscal Year: 2007..It will provide a foundation for larger translational science projects and a context for training the translational scientists of the future. ..
- Mental Health Research Education Grant (R25)Israel Liberzon; Fiscal Year: 2007..This program strives to foster the development of mental health researchers by providing the training, structure, and resources that are necessary to begin an academic, research-focused career in psychiatry. ..