Isaac H Liao

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Tourette syndrome: gene expression as a tool to discover drug targets
    Isaac H Liao
    Medical Investigation of Neurodevelopmental Disorders MIND Institute and Department of Neurology, University of California at Davis, Sacramento, California 95817, USA
    Neurotherapeutics 7:302-6. 2010
  2. doi request reprint Blood gene expression correlated with tic severity in medicated and unmedicated patients with Tourette Syndrome
    Isaac H Liao
    University of California, Davis, CA 9581, USA
    Pharmacogenomics 11:1733-41. 2010
  3. doi request reprint GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: a pilot study
    Yingfang Tian
    University of California at Davis, M I N D, Institute and Department of Neurology, USA
    Brain Res 1381:228-36. 2011
  4. pmc Exon expression and alternatively spliced genes in Tourette Syndrome
    Yingfang Tian
    M I N D Institute, Department of Neurology, University of California at Davis, Sacramento, 95817, USA
    Am J Med Genet B Neuropsychiatr Genet 156:72-8. 2011
  5. pmc Empirical Bayes accomodation of batch-effects in microarray data using identical replicate reference samples: application to RNA expression profiling of blood from Duchenne muscular dystrophy patients
    Wynn L Walker
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, California, USA
    BMC Genomics 9:494. 2008
  6. pmc Recombinant Fv-Hsp70 protein mediates neuroprotection after focal cerebral ischemia in rats
    Xinhua Zhan
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, Calif 95817, USA
    Stroke 41:538-43. 2010
  7. pmc Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood
    Boryana S Stamova
    Department of Neurology and M, Institute, University of California at Davis Medical Center, Sacramento, CA 95817, USA
    BMC Med Genomics 2:49. 2009

Detail Information

Publications7

  1. doi request reprint Tourette syndrome: gene expression as a tool to discover drug targets
    Isaac H Liao
    Medical Investigation of Neurodevelopmental Disorders MIND Institute and Department of Neurology, University of California at Davis, Sacramento, California 95817, USA
    Neurotherapeutics 7:302-6. 2010
    ..Here, we consider the possibility of applying this approach to Tourette syndrome. We also review current theories of Tourette syndrome etiology and pharmacology...
  2. doi request reprint Blood gene expression correlated with tic severity in medicated and unmedicated patients with Tourette Syndrome
    Isaac H Liao
    University of California, Davis, CA 9581, USA
    Pharmacogenomics 11:1733-41. 2010
    ..Gene-expression studies provide valuable insight into the causes of TS; however, many studies of gene expression in TS do not account for the effects of medication...
  3. doi request reprint GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: a pilot study
    Yingfang Tian
    University of California at Davis, M I N D, Institute and Department of Neurology, USA
    Brain Res 1381:228-36. 2011
    ..This pilot study suggests that at least some of these GABA- and ACh-related genes observed in blood that correlate with tics or are alternatively spliced are involved in the pathophysiology of TS and tics...
  4. pmc Exon expression and alternatively spliced genes in Tourette Syndrome
    Yingfang Tian
    M I N D Institute, Department of Neurology, University of California at Davis, Sacramento, 95817, USA
    Am J Med Genet B Neuropsychiatr Genet 156:72-8. 2011
    ..However, the findings are tempered by the small sample size and multiple comparisons and require confirmation using PCR or deep RNA sequencing and a much larger patient population...
  5. pmc Empirical Bayes accomodation of batch-effects in microarray data using identical replicate reference samples: application to RNA expression profiling of blood from Duchenne muscular dystrophy patients
    Wynn L Walker
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, California, USA
    BMC Genomics 9:494. 2008
    ..Existing methods can correct for batch effects only when samples from all biological groups are represented in every batch...
  6. pmc Recombinant Fv-Hsp70 protein mediates neuroprotection after focal cerebral ischemia in rats
    Xinhua Zhan
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, Calif 95817, USA
    Stroke 41:538-43. 2010
    ..This study investigated the effects of intravenous recombinant Fv-Hsp70 protein on infarction volume and behavior after experimental ischemic stroke...
  7. pmc Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood
    Boryana S Stamova
    Department of Neurology and M, Institute, University of California at Davis Medical Center, Sacramento, CA 95817, USA
    BMC Med Genomics 2:49. 2009
    ..These genes should be useful as normalization genes for microarray and RT-PCR whole blood studies of human physiology, metabolism and disease...