Research Topics
| Xiayuan LiangSummaryAffiliation: University of Colorado Country: USA Publications
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Detail Information
Publications
Assessment of t(2;5)(p23;q35) translocation and variants in pediatric ALK+ anaplastic large cell lymphomaXiayuan Liang
Department of Pathology, University of Colorado School of Medicine, Denver, USA
Am J Clin Pathol 121:496-506. 2004....
Primary high-grade B-cell lymphoma of the breast with concurrent IGH-BCL2 and MYC-IGL translocations in an adolescent patientXiayuan Liang
Department of Pathology, The Children s Hospital, Aurora, CO, USA
Pediatr Dev Pathol 14:402-6. 2011....
Gray zone lymphomas in pediatric patientsXiayuan Liang
Department of Pathology, The Children s Hospital, Aurora, CO, USA
Pediatr Dev Pathol 14:57-63. 2011..In this manuscript, we report 2 cases of pediatric patients with gray zone lymphoma and review clinicopathologic features, treatment options, and outcomes of this uncommon tumor...
Natural killer cell neoplasmsXiayuan Liang
Department of Pathology, Children s Hospital, Denver, Colorado, USA
Cancer 112:1425-36. 2008....
Primary ocular adnexal lymphoma in pediatric patients: report of two cases and review of the literatureXiayuan Liang
Department of Pathology, University of Colorado School of Medicine, 4200 East 9th Avenue B216, Denver, CO 80262, USA
Pediatr Dev Pathol 6:458-63. 2003..Here we describe two pediatric cases of POAL and review the literature to further help characterize the clinical features and histopathologic appearance of this uncommon lymphoma...
Thymoma in children: report of 2 cases and review of the literatureXiayuan Liang
Department of Pathology, The Children s Hospital, Aurora, CO, USA
Pediatr Dev Pathol 13:202-8. 2010..The clinicopathologic features, differential diagnosis, and current therapeutic recommendations of this uncommon tumor in pediatric patients are also addressed...
Nonpositive terminal deoxynucleotidyl transferase in pediatric precursor B-lymphoblastic leukemiaLanting Liu
Department of Pathology, University of Colorado School of Medicine, Denver, USA
Am J Clin Pathol 121:810-5. 2004..0019; respectively). These results indicate that nonpositive TdT does not rule out a diagnosis of ALL and suggest that TdT(np) B-cell ALL might be associated with CD10- and CD34- disease, a high WBC count, and MLL gene rearrangement...
BCL6 expression correlates with monomorphic histology in children with posttransplantation lymphoproliferative diseaseChristopher C Porter
Department of Pediatrics, Center for Cancer and Blood Disorders, The Children s Hospital and University of Colorado Denver, Aurora, CO, USA
J Pediatr Hematol Oncol 30:684-8. 2008..19). Recipients of heart transplants who developed PTLD had reduced overall survival rates compared with recipients of other organ transplants who developed PTLD (P=0.04)...
Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemiaDouglas K Graham
Department of Pediatrics, University of Colorado Health Sciences Center, Denver, Colorado, USA
Clin Cancer Res 12:2662-9. 2006....
Precursor natural killer cell leukemiaXiayuan Liang
Department of Pathology, University of Colorado School of Medicine, Denver, USA
Pediatr Blood Cancer 50:876-8. 2008..Here we describe a pediatric patient with precursor NK cell leukemia and review the literature of the previously reported cases in children to further help characterize the diagnosis, treatment, and outcome...
Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivityAmy K Keating
Department of Pediatrics, University of Colorado Denver, Aurora, CO 80045, USA
Mol Cancer Ther 9:1298-307. 2010..Our results suggest Mer and Axl RTK inhibition as a novel method to improve apoptotic response and chemosensitivity in astrocytoma and provide support for these oncogenes as attractive biological targets for astrocytoma drug development...
Posttransplant Hodgkin lymphoma preceded by polymorphic posttransplant lymphoproliferative disorder: report of a pediatric case and review of the literatureGabriela Gheorghe
Department of Pathology, University of Colorado School of Medicine, The Children s Hospital, Denver, CO 80218, USA
J Pediatr Hematol Oncol 29:112-6. 2007....
A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregationSusan Sather
Department of Pediatrics, University of Colorado at Denver, and Health Sciences Center, Aurora, CO 80045, USA
Blood 109:1026-33. 2007..Furthermore, soluble Mer decreased platelet aggregation in vitro and prevented fatal collagen/epinephrine-induced thromboembolism in mice, suggesting a potential therapeutic use for soluble Mer in the treatment of clotting disorders...
Difficult diagnostic and therapeutic cases: CASE 2. thymoma and tumor lysis syndrome in an adolescentAngela D Trobaugh-Lotrario
Department of Pediatric Hematology/Oncology, The Children's Hospital of Denver, Denver, CO, USA
J Clin Oncol 22:955-7. 2004
Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemiaRachel M A Linger
Department of Pediatrics, Section of Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
Blood 114:2678-87. 2009..This strategy may allow for dose reduction resulting in decreased toxicity and increased survival rates. Mer is aberrantly expressed in numerous other malignancies suggesting that this approach may have broad applications...
A case of childhood peripheral T-cell lymphoma with massive cardiac infiltrationLaura Schulz
Department of Hematology Oncology BMT, The Children s Hospital Denver, Colorado 80218, USA
J Pediatr Hematol Oncol 26:48-51. 2004..The authors review briefly the biology of PTCL and the incidence of cardiac involvement with lymphoma, which is not often appreciated prior to death...
Moderate aplastic anemia in children: preliminary outcomes for treatment versus observation from a single-institutional experienceKatharine Brock
Department of Pediatrics, University of Colorado, Aurora, CO, USA
J Pediatr Hematol Oncol 35:148-52. 2013..On an exploratory basis, we sought to evaluate the influence of treatment with immunosuppressive therapy (IST) versus observation on long-term outcomes...
Pseudohypopyon: Extramedullary relapse of acute myelogenous leukemia with poor prognosisWilliam C Petersen
Department of Pediatrics, The Children s Hospital, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA
Pediatr Blood Cancer 52:885-7. 2009..Towards the end of her second course of induction she developed pseudohypopyon in each eye on consecutive days, heralding a central nervous system relapse...
Disseminated nasopharyngeal natural killer cell lymphoblastic lymphoma in a childDouglas K Graham
Department of Hematology, Oncology, and Bone Marrow Transplant, The Children's Hospital, University of Colorado Health Sciences Center, Denver, Colorado 80218, USA
Med Pediatr Oncol 40:251-3. 2003
Rapid onset proptosis and vision loss as the initial presentation of Burkitt lymphomaF Ryan Prall
Department of Ophthalmology, Rocky Mountain Lions Eye Institute, Aurora, CO 80045, USA
Ophthalmic Surg Lasers Imaging 39:331-4. 2008..Given the tumor's rapid growth rate, potential for vision loss, and good response to chemotherapy, clinicians should be aware of this rare presentation...
Successful treatment of severe aplastic anemia in children using standardized immunosuppressive therapy with antithymocyte globulin and cyclosporine ANeil A Goldenberg
Division of Hematology, Oncology, and BMT, Department of Pediatrics, UCHSC The Children s Hospital, Denver, Colorado 80128, USA
Pediatr Blood Cancer 43:718-22. 2004..Given the heterogeneity of published data in US children, we sought to evaluate outcomes of a standardized immunosuppressive therapy (IST) regimen for severe aplastic anemia (SAA) at The Children's Hospital (Denver, CO)...
Toddlers with anasarca and severe anemia: a lesson in preventive medicineJennifer L Salstrom
Department of Pediatric Hematology, Oncology, and Bone Marrow Transplantation, University of Colorado School of Medicine, Aurora, Colorado, USA
Curr Opin Pediatr 24:129-33. 2012..These cases illustrate the importance of the primary medical care provider's role in preventive medicine and provide an example of severe complications that may arise from iron deficiency anemia if it is not recognized and treated early...
