Yuanyuan Li

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, 1300 University Boulevard Birmingham, AL 35294, USA
    Mol Cancer 9:274. 2010
  2. pmc Impact of epigenetic dietary compounds on transgenerational prevention of human diseases
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, 35294, USA
    AAPS J 16:27-36. 2014
  3. pmc Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 8:e54369. 2013
  4. pmc Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Mol Cancer 12:9. 2013
  5. pmc Epigenetic regulation of caloric restriction in aging
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, 1300 University Boulevard, Birmingham, AL 35294, USA
    BMC Med 9:98. 2011
  6. pmc Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    FASEB J 24:1442-53. 2010
  7. pmc Analysis of biomarkers of caloric restriction in aging cells
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 1048:19-29. 2013
  8. pmc p16(INK4a) suppression by glucose restriction contributes to human cellular lifespan extension through SIRT1-mediated epigenetic and genetic mechanisms
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 6:e17421. 2011
  9. pmc Combined chromatin immunoprecipitation and bisulfite methylation sequencing analysis
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 791:239-51. 2011
  10. pmc Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Cancer 125:286-96. 2009

Collaborators

Detail Information

Publications16

  1. pmc Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, 1300 University Boulevard Birmingham, AL 35294, USA
    Mol Cancer 9:274. 2010
    ..Dietary green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), is believed to be an anticancer agent in part through its regulation of epigenetic processes...
  2. pmc Impact of epigenetic dietary compounds on transgenerational prevention of human diseases
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, 35294, USA
    AAPS J 16:27-36. 2014
    ....
  3. pmc Epigenetic regulation of multiple tumor-related genes leads to suppression of breast tumorigenesis by dietary genistein
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 8:e54369. 2013
    ..These studies will facilitate more effective use of soybean product in breast cancer prevention and also help elucidate the mechanisms during the process of early breast tumorigenesis...
  4. pmc Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Mol Cancer 12:9. 2013
    ..However, the role of GE in ERα-negative breast cancer remains unknown...
  5. pmc Epigenetic regulation of caloric restriction in aging
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, 1300 University Boulevard, Birmingham, AL 35294, USA
    BMC Med 9:98. 2011
    ..Enhanced understanding of the important role of epigenetics in the control of the aging process through caloric restriction may lead to clinical advances in the prevention and therapy of human aging-associated diseases...
  6. pmc Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    FASEB J 24:1442-53. 2010
    ..Collectively, these results provide new insights into the epigenetic mechanisms of a nutrient control strategy that may contribute to cancer therapy as well as antiaging approaches...
  7. pmc Analysis of biomarkers of caloric restriction in aging cells
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 1048:19-29. 2013
    ..Hence, we will discuss the detailed procedures of this novel technique as well as the analysis of relevant aging biomarkers and its broad application in the field. ..
  8. pmc p16(INK4a) suppression by glucose restriction contributes to human cellular lifespan extension through SIRT1-mediated epigenetic and genetic mechanisms
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
    PLoS ONE 6:e17421. 2011
    ....
  9. pmc Combined chromatin immunoprecipitation and bisulfite methylation sequencing analysis
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 791:239-51. 2011
    ..In this chapter, we discuss the detailed procedures of this novel technique and its broad application in epigenetic and genetic fields...
  10. pmc Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Cancer 125:286-96. 2009
    ....
  11. pmc Cell senescence culturing methods
    Huaping Chen
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 1048:1-10. 2013
    ..There are many ways to study aging in vitro. In this chapter, we will discuss some of the basic laboratory procedures for cell senescence culturing methods. ..
  12. pmc Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation
    Huaping Chen
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Exp Cell Res 319:697-706. 2013
    ....
  13. pmc Enhancement of Cisplatin-Mediated Apoptosis in Ovarian Cancer Cells through Potentiating G2/M Arrest and p21 Upregulation by Combinatorial Epigallocatechin Gallate and Sulforaphane
    Huaping Chen
    Department of Biology, University of Alabama at Birmingham, CH175, 1300 University Boulevard, Birmingham, AL 35294 1170, USA
    J Oncol 2013:872957. 2013
    ..Collectively, these studies provide novel approaches to overcoming cisplatin chemotherapy resistance in ovarian cancer...
  14. pmc DNA methylation detection: bisulfite genomic sequencing analysis
    Yuanyuan Li
    Department of Biology, University of Alabama at Birmingham, Birmingham, AL, USA
    Methods Mol Biol 791:11-21. 2011
    ..Here, we present a protocol currently frequently used in our laboratory that has proven to yield optimal outcomes. We also discuss the potential technical problems and troubleshooting notes for a variety of applications in this field...
  15. pmc Strategies targeting telomerase inhibition
    Huaping Chen
    Department of Biology, University of Alabama at Birmingham, 175 Campbell Hall, 1300 University Boulevard, Birmingham, AL 35294 1170, USA
    Mol Biotechnol 41:194-9. 2009
    ..This analysis will summarize recent developments of strategies in telomerase inhibition...
  16. pmc 2D difference gel electrophoresis analysis of different time points during the course of neoplastic transformation of human mammary epithelial cells
    J Tyson DeAngelis
    Department of Biology, UAB Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama 35294 1170, USA
    J Proteome Res 10:447-58. 2011
    ....