Research Topics
| Yan LiSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Comparison of T(1) and T(2) metabolite relaxation times in glioma and normal brain at 3TYan Li
University of California, San Francisco University of California, Berkeley UCSF UCB Joint Graduate Group in Bioengineering, San Francisco, California 94143 2532, USA
J Magn Reson Imaging 28:342-50. 2008..To measure T(1) and T(2) relaxation times of metabolites in glioma patients at 3T and to investigate how these values influence the observed metabolite levels...
Three-dimensional J-resolved H-1 magnetic resonance spectroscopic imaging of volunteers and patients with brain tumors at 3TYan Li
University of California, San Francisco University of California, Berkeley Joint Graduate Group in Bioengineering, San Francisco, California 94143 2532, USA
Magn Reson Med 58:886-92. 2007..17 Hz. This technique also enables the evaluation of the changes in metabolite T(2). Compared with the values in normal white matter, the T(2) values of Cho and Cr were statistically significantly increased in regions of glioma...- Serial analysis of imaging parameters in patients with newly diagnosed glioblastoma multiformeYan Li
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158 2532, USA
Neuro Oncol 13:546-57. 2011..Our studies suggest that quantitative MRI variables derived from anatomic and physiological MRI provide useful information for predicting outcome in patients with GBM... - Considerations in applying 3D PRESS H-1 brain MRSI with an eight-channel phased-array coil at 3 TYan Li
UCSF/UCB Joint Graduate Group in Bioengineering, San Francisco, CA 94720, USA
Magn Reson Imaging 24:1295-302. 2006..5 T with a quadrature head coil. This is expected to be critical for clinical applications of MRSI in patients with brain tumors because it can be used to either decrease acquisition time or improve spatial resolution... - Phased array 3D MR spectroscopic imaging of the brain at 7 TDuan Xu
Joint UCSF UC Berkeley Graduate Group in Bioengineering, University of California, San Francisco and Berkeley, CA 94143, USA
Magn Reson Imaging 26:1201-6. 2008..The new 7 T MRSI sequence was tested in volunteer studies and demonstrated the feasibility of obtaining high-SNR phased-array 3D MRSI from the human brain... 
Advances in ultra-high field MRI for the clinical management of patients with brain tumorsJanine M Lupo
Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94158 2330, USA
Curr Opin Neurol 24:605-15. 2011..This is especially important in the current climate in which new treatments alter established markers of tumor and the surrounding environment, confounding traditional response criteria...- A novel intronic polymorphism of ABCA1 gene reveals risk for sporadic Alzheimer's disease in ChineseLeung Wing Chu
Department of Medicine, The University of Hong Kong, Hong Kong
Am J Med Genet B Neuropsychiatr Genet 144:1007-13. 2007..Further functional analysis of this polymorphism should be a high priority... - Polymorphisms of the DNA repair gene xeroderma pigmentosum groups A and C and risk of esophageal squamous cell carcinoma in a population of high incidence region of North ChinaWei Guo
Hebei Cancer Institute, The Fourth Hospital of Hebei Medical University, Jiankanglu 12, 050011 Shijiazhuang, Hebei, China
J Cancer Res Clin Oncol 134:263-70. 2008..The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) of xeroderma pigmentosum group A (XPA) and XPC can influence the risk of esophageal squamous cell carcinoma (ESCC)... - Neurofibromin-deficient Schwann cells have increased lysophosphatidic acid dependent survival and migration-implications for increased neurofibroma formation during pregnancyTodd D Nebesio
Department of Pediatrics, Herman B Wells Center for Pediatric Cancer Research Institute, Indiana University School of Medicine, Indianapolis, Indiana, USA
Glia 55:527-36. 2007.... - Sun exposure, vitamin D receptor gene polymorphisms and risk of non-Hodgkin lymphomaMark P Purdue
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8009, Rockville, MD 20892, USA
Cancer Causes Control 18:989-99. 2007.... - Subsequently enhanced CPP to morphine following chronic but not acute footshock stress associated with corticosterone mechanism in ratsYan Li
Department of Psychiatry, The Second Xiangya Hospital, Central South University, Changsha Hunan, PR China
Int J Neurosci 117:1237-55. 2007..The dopamine levels in NAc of rats injected with CORT (5, 3, 1 mg/kg, i.p.) increased significantly. The findings suggest that the increase of dopamine levels in NAc induced by CORT might be the medium between stress and morphine... - Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathwayYan Li
Department of Pharmacology, Zhong Shan Medical College, Sun Yat Sen University, Guangzhou 510089, China
Proc Natl Acad Sci U S A 104:13438-43. 2007..Furthermore, activation of the protein kinase A/cAMP-responsive element binding protein pathway may be a key and requisite factor in glioma differentiation... - Rationales for expression and altered expression of apoptotic protease activating factor-1 gene in gastric cancerHe Ling Wang
Department of Gastroenterology, Shengjing Hospital Affiliated to China Medical University, Shenyang110004, Liaoning Province, China
World J Gastroenterol 13:5060-4. 2007..To elucidate the relationship between apoptotic protease activating factor-1 (Apaf-1) gene and gastric cancer... - Proteasome inhibition is associated with manganese-induced oxidative injury in PC12 cellsTongjian Cai
Department of Occupational and Environmental Health, Fourth Military Medical University, Xi an 710032, China
Brain Res 1185:359-65. 2007..In conclusion, our results imply that proteasome inhibition may be associated with manganese-induced cytotoxicity in dopaminergic neurons, which may be connected with oxidative damage... - E-cadherin gene polymorphisms and haplotype associated with the occurrence of epithelial ovarian cancer in ChineseYan Li
Department of Molecular Biology, Hebei Cancer Institute, Hebei Medical University, Fourth Hospital, Jiankanglu 12, Shijiazhuang 050011, China
Gynecol Oncol 108:409-14. 2008..The polymorphisms located at the E-cadherin may contribute to an increased risk for certain cancers. In this paper, we studied the association between polymorphisms of E-cadherin and the risk of epithelial ovarian cancer... - Vegetables- and antioxidant-related nutrients, genetic susceptibility, and non-Hodgkin lymphoma riskLinda E Kelemen
Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA
Cancer Causes Control 19:491-503. 2008..Although most associations have not been examined previously with NHL, our results suggest the examined polymorphisms are not modifiers of the association between vegetable and zinc intakes and NHL risk... - Association of a functional cytochrome P450 4F2 haplotype with urinary 20-HETE and hypertensionHong Liu
Department of Medical Genetics, China Medical University, No92, Bei Er Road, Shenyang, 110001, China
J Am Soc Nephrol 19:714-21. 2008..These results indicate that a functional variant of the CYP4F2 regulatory region, which increases the binding affinity of NF-kappaB, increases the risk for hypertension, likely by modulating the production of 20-HETE... - Polymorphisms in the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 and the risk of human adenomyosisShan Kang
Department of Obstetrics and Gynaecology, Hebei Medical University, Fourth Hospital, Shijiazhuang, China
Environ Mol Mutagen 49:226-31. 2008..Our results indicated an association of MMP-2 -1306C/T polymorphism with the risk of adenomyosis, suggesting a potential role in adenomyosis development in North Chinese women... - Expression of GLUT-1 in psoriasis and the relationship between GLUT-1 upregulation induced by hypoxia and proliferation of keratinocyte growthJuan Tao
J Dermatol Sci 51:203-7. 2008 - Minimally invasive surgical pulmonary vein isolation alone for persistent atrial fibrillation: preliminary results of epicardial atrial electrogram analysisHui Li
Beijing Anzhen Hospital, Capital Medical University, Beijing, Peoples Republic of China
Ann Thorac Surg 86:1219-25. 2008..Minimally invasive surgical pulmonary vein isolation has become an alterative therapy for lone atrial fibrillation. This study evaluated the effect of the procedure on persistent atrial fibrillation by epicardial atrial electrography... - Two new compounds from Dendrobium candidumYan Li
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
Chem Pharm Bull (Tokyo) 56:1477-9. 2008..Five previously known bibenzyls were also identified: 4,4'-dihydroxy-3,5-dimethoxybibenzyl (3), 3,4-dihydroxy-5,4'-dimethoxybibenzyl (4), 3-O-methylgigantol (5), dendrophenol (6), and gigantol (7)... - Inhibition by oxytocin of methamphetamine-induced hyperactivity related to dopamine turnover in the mesolimbic region in miceJia Qi
Department of Pharmacology, Shenyang Pharmaceutical University, 110016, Shenyang, People s Republic of China
Naunyn Schmiedebergs Arch Pharmacol 376:441-8. 2008..These results suggested that OT inhibited the MAP-induced hyperactivity by altering the DA turnover in the mesolimbic region of mice... - Association of MTHFR C677T and SHMT(1) C1420T with susceptibility to ESCC and GCA in a high incident region of Northern ChinaYimin Wang
Hebei Cancer Institute, Hebei Medical University, Jiankanglu 12, Shijiazhuang, 050011, Hebei Province, China
Cancer Causes Control 18:143-52. 2007.... - Mutation-positive and mutation-negative patients with Cowden and Bannayan-Riley-Ruvalcaba syndromes associated with distinct 10q haplotypesMarcus G Pezzolesi
Genomic Medicine Institute, Cleveland Clinic Lerner Research Institute, Cleveland, OH, 44195, USA
Am J Hum Genet 79:923-34. 2006.... - Association of the thymidylate synthase polymorphisms with esophageal squamous cell carcinoma and gastric cardiac adenocarcinomaJianhui Zhang
Hebei Cancer Institute, Hebei Medical University, Shijiazhuang 050011, Hebei Province, China
Carcinogenesis 25:2479-85. 2004..67-49.74). The results suggested that the TS polymorphisms might be associated with the susceptibility to ESCC and GCA, and the 2R/3G genotype might be a candidate marker to predict the potential of lymphatic metastasis in ESCC... - [Primary studies on synthesis and properties of mitoxantrone-insulin conjugates]Wen-Sheng Liu
Department of Pharmaceatics, West China School of Pharmacy, Sichuan University, Chengdu 610041, China
Sichuan Da Xue Xue Bao Yi Xue Ban 35:264-6. 2004..68%. The conjugate was stable in phosphate buffer solution of pH 2-8 and mouse plasma at 37 degrees C. CONCLUSION: Stable mitoxantrone-insulin conjugate was obtained to ensure further tumor targeted study in vivo... - Attenuation of free radical production and paracrystalline inclusions by creatine supplementation in a patient with a novel cytochrome b mutationMark A Tarnopolsky
Department of Medicine, McMaster University Medical Center, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
Muscle Nerve 29:537-47. 2004..The results suggest that the development of exercise-induced paracrystalline inclusions may be influenced by the G15497A mtDNA mutation, and that CM mitigates against the pathological consequences of this mutation... - [Reconstruction algorithms of computed tomography of remote sensing FTIR]Zhong-Hua Huang
Laboratory of Advanced Spectroscopy, Nanjing University of Science and Technology, Nanjing 210014, China
Guang Pu Xue Yu Guang Pu Fen Xi 22:973-5. 2002..Comparing to ART, MART has the advantages of iterative speed and iterative precision, while SIRT overcomes the problem of illegibility and SBFM can reduce the noise sharply... - NQO1 C609T polymorphism associated with esophageal cancer and gastric cardiac carcinoma in North ChinaJian hui Zhang
Hebei Cancer Institute, Shijiazhuang 050011, China
World J Gastroenterol 9:1390-3. 2003..To investigate the association of the NQO1 (C609T) polymorphism with susceptibility to esophageal squamous cell carcinoma (ESCC) and gastric cardiac adenocarcinoma (GCA) in North China... - Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese populationJianhui Zhang
Institute of Pathology, University of Duesseldorf, Moorenstr 5, Germany
Carcinogenesis 24:905-9. 2003..In summary, the association of the NQO1 C609T polymorphism with ESCC in genetically distinct populations makes a strong argument for its importance in carcinogenesis of ESCC in the German Caucasian and the northern Chinese population... - Identification of the metabolites of 9-nitro-20(S)-camptothecin in ratsKe Li
Laboratory of Drug Metabolism and Pharmacokinetics, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016, P. R. China
Drug Metab Dispos 31:792-7. 2003..The mercapturic acid conjugate of 10-hydroxy-20(S)-camptothecin (M6) was detected in the urine and feces by LC/MSn.. - Association of cyclin D1 (G870A) polymorphism with susceptibility to esophageal and gastric cardiac carcinoma in a northern Chinese populationJianhui Zhang
Laboratory of Molecular Biology, Hebei Cancer Institute, Hebei Medical University, Shijiazhuang, People s Republic of China
Int J Cancer 105:281-4. 2003..Determination of the cyclin D1 (G870A) single nucleotide polymorphism may be suitable to identify individuals with increased risk for ESCC or CAC in the northern Chinese population... - The functional SNP in the matrix metalloproteinase-3 promoter modifies susceptibility and lymphatic metastasis in esophageal squamous cell carcinoma but not in gastric cardiac adenocarcinomaJianhui Zhang
Hebei Cancer Institute, Hebei Medical University, Jiankanglu 12, Shijiazhuang 050011, Hebei Province, China
Carcinogenesis 25:2519-24. 2004..The present study suggests that the MMP3 promoter SNP might be associated with a risk of development and lymphatic metastasis in ESCC but not in GCA... - Methylenetetrahydrofolate reductase C677T polymorphism and predisposition towards esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese populationJianhui Zhang
Institute of Pathology, University of Dusseldorf, Germany
J Cancer Res Clin Oncol 130:574-80. 2004..The purpose of this study is to compare the association of the MTHFR C677T polymorphism with susceptibility to esophageal squamous cell carcinoma (ESCC)... - Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North ChinaShumei Fang
Hebei Cancer Institute, Hebei Medical University, Shijiazhuang 050011, Hebei Province, China
Carcinogenesis 26:481-6. 2005..42-7.94), compared with the 2G/6A haplotype. The present result suggested that the MMP3 promoter polymorphism may modify susceptibility to NSCLC, and the MMP 1G/5A haplotype may predicate the risk of lymphatic metastasis of this tumor... - Distribution of the functional MDR1 C3435T polymorphism in the Han population of ChinaYanhong Li
Lab of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China
Swiss Med Wkly 136:377-82. 2006..It was found that ethnic differences exist in the polymorphism of the MDR1(C3435T) gene. However, the distribution of 3435C>T genotypes in the Chinese Han population is not clear up till now... - Ambulatory arterial stiffness index derived from 24-hour ambulatory blood pressure monitoringYan Li
Centre for Epidemiological Studies and Clinical Trials, Ruijin Hospital, Institute of Hypertension, Shanghai Second Medical University, Shanghai, China
Hypertension 47:359-64. 2006..Pending additional validation in outcome studies, normal values of AASI are probably <0.50 and 0.70 in young and older subjects, respectively... - Association of manganese superoxide dismutase expression with progression of carcinogenesis in Barrett esophagusBruce Hermann
Department of Surgery, Division of Surgical Oncology, University of Louisville School of Medicine, Louisville, KY 40202, USA
Arch Surg 140:1204-9; discussion 1209. 2005..Further evaluation within genotypic expression and the role of antioxidants is needed in the effective screening and treatment of BE... - [Measurement of morphological parameters of Cryptosporidium muris oocysts by digital image processing technology]Yu-Yan Bing
Department of Pathogenic Biology, China Medical University, Shenyang 110001, China
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 23:175-7. 2005..03 microm and the average area was 16.08 microm2. CONCLUSION: Data obtained from the computer system are objective and precise, offering scientific foundation for measuring the oocysts and for identifying Cryptosporidium spp... - Polymorphisms in the promoter regions of the matrix metalloproteinases-1, -3, -7, and -9 and the risk of epithelial ovarian cancer in ChinaYan Li
Hebei Cancer Institute, Hebei Medical University, Jiankanglu 12, Shijiazhuang 050011, Hebei Province, China
Gynecol Oncol 101:92-6. 2006.... - A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agentsHongliang Jiang
Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
J Control Release 108:237-43. 2005..It was revealed that the released lysozyme maintained its structure and bioactivity. The current method may find wide applications for controlled release of proteins and tissue engineering... - No association between the C-1562T polymorphism in the promoter of matrix metalloproteinase-9 gene and non-small cell lung carcinomaYimin Wang
Hebei Cancer Institute, Hebei Medical University, Jiankanglu 12, Shijiazhuang 050011, Hebei Province, China
Lung Cancer 49:155-61. 2005..Therefore, the present study suggests that the MMP-9 C-1562T polymorphism may not be used as a useful marker to predicate susceptibility and lymphatic metastasis in NSCLC... - Developmental changes in spinal motoneuron dendrites in neonatal miceYan Li
Laboratory of Neural Control, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
J Comp Neurol 483:304-17. 2005..The relative constancy of MN dendritic topology up to P13 was surprising, given the striking maturation in motor function during this time period... - Association of metallothionein expression and lack of apoptosis with progression of carcinogenesis in Barrett's esophagusYan Li
Division of Gastroenterology/Hepatology, Department of Medicine, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
Exp Biol Med (Maywood) 228:286-92. 2003..This study thus suggests that MT may contribute to cytoprotection, thereby inhibiting apoptosis and leading to carcinogenesis of Barrett's esophageal cells...