Wen Hong Li

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Fluorescent probes for monitoring regulated secretion
    Wen Hong Li
    Department of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390 9039, United States
    Curr Opin Chem Biol 17:672-81. 2013
  2. pmc Photoactivatable fluorophores and techniques for biological imaging applications
    Wen Hong Li
    Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    Photochem Photobiol Sci 11:460-71. 2012
  3. pmc Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent
    Genhua Zheng
    Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9039, USA
    Silence 1:9. 2010
  4. ncbi LAMP, a new imaging assay of gap junctional communication unveils that Ca2+ influx inhibits cell coupling
    Kenneth Dakin
    Department of Cell Biology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Nat Methods 2:55-62. 2005
  5. ncbi Local Ca2+ rise near store operated Ca2+ channels inhibits cell coupling during capacitative Ca2+ influx
    Kenneth Dakin
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, 75390 9039, USA
    Cell Commun Adhes 13:29-39. 2006
  6. pmc Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR)
    Daliang Li
    Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9039, USA
    Proc Natl Acad Sci U S A 108:21063-8. 2011
  7. ncbi A new class of macrocyclic lanthanide complexes for cell labeling and magnetic resonance imaging applications
    Quan Zheng
    Department of Cell Biology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    J Am Chem Soc 127:16178-88. 2005
  8. ncbi New caged coumarin fluorophores with extraordinary uncaging cross sections suitable for biological imaging applications
    YuRui Zhao
    Department of Cell Biology and Biochemistry, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    J Am Chem Soc 126:4653-63. 2004
  9. ncbi Photoactivatable and water soluble FRET dyes with high uncaging cross section
    Genhua Zheng
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Am Chem Soc 129:10616-7. 2007
  10. doi Imaging dynamic cell-cell junctional coupling in vivo using Trojan-LAMP
    Yan Ming Guo
    Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390, USA
    Nat Methods 5:835-41. 2008

Collaborators

Detail Information

Publications15

  1. pmc Fluorescent probes for monitoring regulated secretion
    Wen Hong Li
    Department of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390 9039, United States
    Curr Opin Chem Biol 17:672-81. 2013
    ..This review summarizes different strategies and recent progress in developing fluorescent sensors for imaging regulated cell secretion. ..
  2. pmc Photoactivatable fluorophores and techniques for biological imaging applications
    Wen Hong Li
    Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    Photochem Photobiol Sci 11:460-71. 2012
    ....
  3. pmc Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent
    Genhua Zheng
    Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9039, USA
    Silence 1:9. 2010
    ..Presently no antisense reagents are available for inhibiting miRNAs in the nematode C. elegans...
  4. ncbi LAMP, a new imaging assay of gap junctional communication unveils that Ca2+ influx inhibits cell coupling
    Kenneth Dakin
    Department of Cell Biology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Nat Methods 2:55-62. 2005
    ..The noninvasive and quantitative nature of this imaging technique should facilitate future investigations of the dynamic regulation of gap junction communication...
  5. ncbi Local Ca2+ rise near store operated Ca2+ channels inhibits cell coupling during capacitative Ca2+ influx
    Kenneth Dakin
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, 75390 9039, USA
    Cell Commun Adhes 13:29-39. 2006
    ..Capacitative Ca(2+) influx also caused a strong reduction of cell coupling, suggesting that the inhibitory effect by Ca(2+) influx may be a more general phenomenon...
  6. pmc Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR)
    Daliang Li
    Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9039, USA
    Proc Natl Acad Sci U S A 108:21063-8. 2011
    ..In addition to studying stimulation-secretion coupling in cells with Zn(2+)-containing granules, ZIMIR may find applications in β-cell engineering and screening for molecules regulating insulin secretion on high-throughput platforms...
  7. ncbi A new class of macrocyclic lanthanide complexes for cell labeling and magnetic resonance imaging applications
    Quan Zheng
    Department of Cell Biology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    J Am Chem Soc 127:16178-88. 2005
    ..The combined advantages of this new class of macrocyclic contrast agents ensure future imaging applications to track cell movement and localization in different biological systems...
  8. ncbi New caged coumarin fluorophores with extraordinary uncaging cross sections suitable for biological imaging applications
    YuRui Zhao
    Department of Cell Biology and Biochemistry, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    J Am Chem Soc 126:4653-63. 2004
    ....
  9. ncbi Photoactivatable and water soluble FRET dyes with high uncaging cross section
    Genhua Zheng
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    J Am Chem Soc 129:10616-7. 2007
  10. doi Imaging dynamic cell-cell junctional coupling in vivo using Trojan-LAMP
    Yan Ming Guo
    Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390, USA
    Nat Methods 5:835-41. 2008
    ..As dextran-CANPE-HCC is chemically and metabolically stable, Labeled worms showed very bright signal upon photoactivation after hatching, which allowed us to examine cell coupling in living worms noninvasively...
  11. doi Assaying dynamic cell-cell junctional communication using noninvasive and quantitative fluorescence imaging techniques: LAMP and infrared-LAMP
    Song Yang
    Department of Cell Biology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
    Nat Protoc 4:94-101. 2009
    ..It takes roughly 3 h or 4 h to complete a LAMP or an infrared-LAMP assay, respectively...
  12. pmc Capacity for stochastic self-renewal and differentiation in mammalian spermatogonial stem cells
    Zhuoru Wu
    Cecil H and Ida Green Center for Reproductive Biology Sciences, Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    J Cell Biol 187:513-24. 2009
    ..These findings provide an experimental basis for autonomous and stochastic fate choice as an alternative strategy for SSC fate bifurcation, which may also be relevant to other stem cell types...
  13. pmc Temporal and Spatial Regulation of MicroRNA Activity with Photoactivatable Cantimirs
    Genhua Zheng
    Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390 9039, United States
    ACS Chem Biol 6:1332-8. 2011
    ..elegans nervous system. This suggests that a transient input of lsy-6 during development is sufficient to specify the neuronal cell fate...
  14. ncbi Cell membrane permeable esters of D-myo-inositol 1,4,5-trisphosphate
    Kenneth Dakin
    Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blouvard, Dallas, TX 75390 9039, United States
    Cell Calcium 42:291-301. 2007
    ..The complementary advantages of these IP3 prodrugs should provide new approaches for studying IP3-Ca2+ signaling in intact cell populations with high spatiotemporal resolutions...
  15. ncbi Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic
    Rene Bartz
    Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9039, USA
    J Lipid Res 48:837-47. 2007
    ..These results suggest that droplets play a central role in ether lipid metabolism and intracellular lipid traffic...