Research Topics
| Wen Hong LiSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Photoactivatable fluorophores and techniques for biological imaging applicationsWen Hong Li
Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
Photochem Photobiol Sci 11:460-71. 2012....
Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagentGenhua Zheng
Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9039, USA
Silence 1:9. 2010..Presently no antisense reagents are available for inhibiting miRNAs in the nematode C. elegans...
Imaging dynamic cell-cell junctional coupling in vivo using Trojan-LAMPYan Ming Guo
Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390, USA
Nat Methods 5:835-41. 2008..As dextran-CANPE-HCC is chemically and metabolically stable, Labeled worms showed very bright signal upon photoactivation after hatching, which allowed us to examine cell coupling in living worms noninvasively...
Assaying dynamic cell-cell junctional communication using noninvasive and quantitative fluorescence imaging techniques: LAMP and infrared-LAMPSong Yang
Department of Cell Biology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390, USA
Nat Protoc 4:94-101. 2009..It takes roughly 3 h or 4 h to complete a LAMP or an infrared-LAMP assay, respectively...
Imaging dynamic insulin release using a fluorescent zinc indicator for monitoring induced exocytotic release (ZIMIR)Daliang Li
Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9039, USA
Proc Natl Acad Sci U S A 108:21063-8. 2011..In addition to studying stimulation-secretion coupling in cells with Zn(2+)-containing granules, ZIMIR may find applications in β-cell engineering and screening for molecules regulating insulin secretion on high-throughput platforms...
Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid trafficRene Bartz
Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9039, USA
J Lipid Res 48:837-47. 2007..These results suggest that droplets play a central role in ether lipid metabolism and intracellular lipid traffic...
Cell membrane permeable esters of D-myo-inositol 1,4,5-trisphosphateKenneth Dakin
Department of Cell Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blouvard, Dallas, TX 75390 9039, United States
Cell Calcium 42:291-301. 2007..The complementary advantages of these IP3 prodrugs should provide new approaches for studying IP3-Ca2+ signaling in intact cell populations with high spatiotemporal resolutions...
Capacity for stochastic self-renewal and differentiation in mammalian spermatogonial stem cellsZhuoru Wu
Cecil H and Ida Green Center for Reproductive Biology Sciences, Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
J Cell Biol 187:513-24. 2009..These findings provide an experimental basis for autonomous and stochastic fate choice as an alternative strategy for SSC fate bifurcation, which may also be relevant to other stem cell types...
Temporal and Spatial Regulation of MicroRNA Activity with Photoactivatable CantimirsGenhua Zheng
Departments of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390 9039, United States
ACS Chem Biol 6:1332-8. 2011..elegans nervous system. This suggests that a transient input of lsy-6 during development is sufficient to specify the neuronal cell fate...
Research Grants
- Beta-Cell Mass And Function In Implants and PancreasWen Hong Li; Fiscal Year: 2003..abstract_text> ..
- Photo-activatable fluorophores and techniques for biological imaging applicationsWen Hong Li; Fiscal Year: 2007....
- Photo-activatable fluorophores and techniques for biological imaging applicationsWen Hong Li; Fiscal Year: 2009....
- Photo-activatable fluorophores and techniques for biological imaging applicationsWen Hong Li; Fiscal Year: 2010....
