Ping Li

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi request reprint RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis
    Ping Li
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Bone Miner Res 19:207-13. 2004
  2. pmc Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis
    Christopher T Ritchlin
    Allergy, Immunology and Rheumatology Unit, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Clin Invest 111:821-31. 2003
  3. ncbi request reprint Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression
    Zhenqiang Yao
    Department of Pathology, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Biol Chem 281:11846-55. 2006
  4. ncbi request reprint TNF-alpha and pathologic bone resorption
    Brendan F Boyce
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Keio J Med 54:127-31. 2005
  5. ncbi request reprint Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice
    Ping Li
    University of Rochester Medical Center, Rochester, New York 14642, USA
    Arthritis Rheum 50:265-76. 2004
  6. pmc Reduction of particle-induced osteolysis by interleukin-6 involves anti-inflammatory effect and inhibition of early osteoclast precursor differentiation
    Michael Darowish
    Center for Musculoskeletal Research, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    Bone 45:661-8. 2009
  7. ncbi request reprint The TNF-alpha transgenic mouse model of inflammatory arthritis
    Ping Li
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Springer Semin Immunopathol 25:19-33. 2003
  8. ncbi request reprint Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis
    Guoyong Yin
    Center for Cardiovascular Research, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, New York 14642, USA
    Mol Ther 5:547-54. 2002
  9. doi request reprint Early involvement of synapsin III in neural progenitor cell development in the adult hippocampus
    Hung Teh Kao
    Nathan Kline Institute for Psychiatric Research and the Department of Psychiatry, New York University School of Medicine, Orangeburg, New York 10962, USA
    J Comp Neurol 507:1860-70. 2008
  10. ncbi request reprint Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP
    Sunbin Liu
    Abteilung Zelluläre Biochemie, Max Planck Institut fur biophysikalische Chemie, Am Fassberg 11, D 37077 Gottingen, Germany
    Science 316:115-20. 2007

Collaborators

Detail Information

Publications60

  1. ncbi request reprint RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis
    Ping Li
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Bone Miner Res 19:207-13. 2004
    ..RANK signaling is not required for the TNFalpha-stimulated increase in CD11b(hi) osteoclast precursors but is essential for mature osteoclast formation...
  2. pmc Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis
    Christopher T Ritchlin
    Allergy, Immunology and Rheumatology Unit, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Clin Invest 111:821-31. 2003
    ..This leads to osteoclastogenesis at the erosion front and in subchondral bone, resulting in a bidirectional assault on psoriatic bone...
  3. ncbi request reprint Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression
    Zhenqiang Yao
    Department of Pathology, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Biol Chem 281:11846-55. 2006
    ..Therefore, the first step of TNF-induced osteoclastogenesis is at the level of OCP genesis in the bone marrow, which represents another layer of regulation to control erosive disease...
  4. ncbi request reprint TNF-alpha and pathologic bone resorption
    Brendan F Boyce
    Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Keio J Med 54:127-31. 2005
    ..Here we review our current understanding of the mechanisms whereby TNFa increases osteoclastogenesis in vitro and in vivo...
  5. ncbi request reprint Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice
    Ping Li
    University of Rochester Medical Center, Rochester, New York 14642, USA
    Arthritis Rheum 50:265-76. 2004
    ..To investigate the mechanisms whereby tumor necrosis factor alpha (TNFalpha) increases osteoclastogenesis in vivo...
  6. pmc Reduction of particle-induced osteolysis by interleukin-6 involves anti-inflammatory effect and inhibition of early osteoclast precursor differentiation
    Michael Darowish
    Center for Musculoskeletal Research, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    Bone 45:661-8. 2009
    ..Thus, the absence of IL-6 results in increased inflammatory bone loss...
  7. ncbi request reprint The TNF-alpha transgenic mouse model of inflammatory arthritis
    Ping Li
    Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Springer Semin Immunopathol 25:19-33. 2003
    ....
  8. ncbi request reprint Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis
    Guoyong Yin
    Center for Cardiovascular Research, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, New York 14642, USA
    Mol Ther 5:547-54. 2002
    ..These data suggest a novel mechanism by which endostatin inhibits angiogenesis, and demonstrates the potential utility of anti-angiogenic gene therapy for treatment of inflammatory arthritis...
  9. doi request reprint Early involvement of synapsin III in neural progenitor cell development in the adult hippocampus
    Hung Teh Kao
    Nathan Kline Institute for Psychiatric Research and the Department of Psychiatry, New York University School of Medicine, Orangeburg, New York 10962, USA
    J Comp Neurol 507:1860-70. 2008
    ..These findings suggest a distinct function for this synaptic vesicle protein, in addition to its role in neurotransmission...
  10. ncbi request reprint Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP
    Sunbin Liu
    Abteilung Zelluläre Biochemie, Max Planck Institut fur biophysikalische Chemie, Am Fassberg 11, D 37077 Gottingen, Germany
    Science 316:115-20. 2007
    ..Yeast two-hybrid analyses suggest a link between retinitis pigmentosa and an aberrant hPrp31-hPrp6 interaction that blocks U4/U6-U5 tri-snRNP formation...
  11. pmc Oxidative phenotype protects myofibers from pathological insults induced by chronic heart failure in mice
    Ping Li
    Division of Cardiology, Department of Medicine, Duke University Medical Center, 4321 Medical Park Dr, Suite 200, Durham, NC 27704, USA
    Am J Pathol 170:599-608. 2007
    ..These findings suggest that exercise intolerance can occur in CHF without fiber type switching in skeletal muscle and that oxidative phenotype renders myofibers resistant to pathological insults induced by CHF...
  12. ncbi request reprint Evidence that maturation of the N-linked glycans of the respiratory syncytial virus (RSV) glycoproteins is required for virus-mediated cell fusion: The effect of alpha-mannosidase inhibitors on RSV infectivity
    Terence P McDonald
    MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK
    Virology 350:289-301. 2006
    ..Our data suggest that glycan maturation of the RSV glycoproteins, in particular those on the F protein, is an important step in virus maturation and is required for virus infectivity...
  13. ncbi request reprint Affinity and kinetic analysis of Fcgamma receptor IIIa (CD16a) binding to IgG ligands
    Ping Li
    Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA
    J Biol Chem 282:6210-21. 2007
    ..These data add to our understanding of IgG-FcgammaR interactions...
  14. ncbi request reprint Two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-brain interface
    Xiaojian Sun
    Department of Psychiatry, Kinsmen Laboratory of Neurological Research and Brain Research Centre, University of British Columbia, Vancouver V6T 1Z3, British Columbia, Canada
    J Biol Chem 281:17420-31. 2006
    ..In conclusion, mapping of glutathione levels in intact brain demonstrates a unique role for enhanced redox potential in developing neurons and cells at the cerebrospinal fluid and blood-brain interface...
  15. ncbi request reprint Cutting edge: rho activation and actin polarization are dependent on plexin-A1 in dendritic cells
    So Young Eun
    Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA
    J Immunol 177:4271-5. 2006
    ..We propose a mechanism of adaptive immune regulation in which plexin-A1 controls Rho activation and actin cytoskeletal rearrangements in DCs that is associated with enhanced DC-T cell interactions...
  16. ncbi request reprint [Comparative study on effects of rutin and quercetin on metabolism in osteoblast cells]
    Ya jun Yang
    Department of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing 210038, China
    Zhong Yao Cai 29:467-70. 2006
    ..To investigate the mechanism of rutin and its aglycone (quercetin) in preventing and treating osteoporosis and their effects on stimulating bone formation were studied comparatively in osteoblast cells...
  17. ncbi request reprint [Effect of multiple amino acid substitutions of collagen II 263-272 on collagen-induced arthritis]
    Ru Li
    Department of Rheumatology and Immunology, Peking University People s Hospital, Beijing 100044, China
    Beijing Da Xue Xue Bao 38:360-4. 2006
    ..To evaluate the effect of multiple amino acid substitutions of C II 263-272 peptide on collagen-induced arthritis, and explore a therapeutic strategy of rheumatoid arthritis...
  18. ncbi request reprint Induction of an effective anti-tumor immune response and tumor regression by combined administration of IL-18 and Apoptin
    Hai Lian
    Genetic Engineering Laboratory, Academy of Military Medical Sciences, 1068 Qinglong Road, Changchun, Jilin 130062, People s Republic of China
    Cancer Immunol Immunother 56:181-92. 2007
    ..These results demonstrate that vaccination with Apoptin together with IL-18 may be a novel and powerful strategy for cancer immunotherapy...
  19. ncbi request reprint Linear energy transfer dependence of the effects of carbon ion beams on adventitious shoot regeneration from in vitro leaf explants of Saintpaulia ionahta
    Libin Zhou
    Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, PR China
    Int J Radiat Biol 82:473-81. 2006
    ....
  20. ncbi request reprint Extensive turnover of dendritic spines and vascular remodeling in cortical tissues recovering from stroke
    Craig E Brown
    Department of Psychiatry, Brain Research Center, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3
    J Neurosci 27:4101-9. 2007
    ....
  21. ncbi request reprint A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis
    Sahoko Ichihara
    Department of Human Functional Genomics, Life Science Research Center, Mie University, 1577 Kurimamachiya cho, Tsu 514 8507, Japan
    Arterioscler Thromb Vasc Biol 27:1297-304. 2007
    ..We have investigated the interaction between AHR and hypoxia signaling pathways in regulation of angiogenesis with the use of a surgical model of ischemia...
  22. ncbi request reprint Regulation of haptoglobin expression in a human keratinocyte cell line HaCaT by inflammatory cytokines and dexamethasone
    Li Xin Xia
    Department of Dermatology, No 1 Hospital of China Medical University, Shenyang, Liaoning 110001, China
    Chin Med J (Engl) 121:730-4. 2008
    ..In this study we investigated the regulation of Hp expression in a human keratinocyte cell line HaCaT by various cytokines and glucocorticoid...
  23. doi request reprint Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury
    Zhong Fang Lai
    Dept of Pharmacology and Molecular Therapeutics, Graduate School of Medical Sciences, Kumamoto Univ, Kumamoto 860 8556, Japan
    Am J Physiol Heart Circ Physiol 295:H708-16. 2008
    ..Therefore, modulation of TNNI3K activity would be a useful therapeutic approach for ischemic cardiac disease...
  24. pmc Functional interaction of regulatory factors with the Pgc-1alpha promoter in response to exercise by in vivo imaging
    Takayuki Akimoto
    Department of Medicine, Duke University Medical Center, Durham, NC 27704, USA
    Am J Physiol Cell Physiol 295:C288-92. 2008
    ..These findings provide in vivo evidence for functional interactions between PKD/HDAC5 and ATF2 regulatory factors and the Pgc-1alpha gene in adult skeletal muscle...
  25. doi request reprint Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines
    Timothy H Murphy
    Kinsmen Laboratory, Department of Psychiatry, Brain Research Center, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3
    J Neurosci 28:1756-72. 2008
    ..Our results identify glutamate receptor-independent ischemic depolarization as the major ionic event associated with disruption of synaptic structure during the first few minutes of ischemia in vivo...
  26. ncbi request reprint The two channel catfish intelectin genes exhibit highly differential patterns of tissue expression and regulation after infection with Edwardsiella ictaluri
    Tomokazu Takano
    The Fish Molecular Genetics and Biotechnology Laboratory, Department of Fisheries and Allied Aquacultures and Program of Cell and Molecular Biosciences, Aquatic Genomics Unit, Auburn University, Auburn, AL 36849, USA
    Dev Comp Immunol 32:693-705. 2008
    ....
  27. ncbi request reprint Mice expressing ACE only in the heart show that increased cardiac angiotensin II is not associated with cardiac hypertrophy
    Hong D Xiao
    Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA
    Am J Physiol Heart Circ Physiol 294:H659-67. 2008
    ....
  28. pmc Adenosine A2A receptor activation and macrophage-mediated experimental glomerulonephritis
    Gabriela E Garcia
    Department of Medicine, Nephrology Section, Alkek N520, One Baylor Plaza, Houston TX, 77030, USA
    FASEB J 22:445-54. 2008
    ..Accordingly, pharmacological activation of A(2A)R could be developed into a novel treatment for glomerulonephritis and other macrophage-related inflammatory diseases...
  29. pmc Vaccinia virus infection induces dendritic cell maturation but inhibits antigen presentation by MHC class II
    Yongxue Yao
    Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Cell Immunol 246:92-102. 2007
    ..Thus, during the early stage of a VV infection, although DC are impaired in some of the critical antigen presentation functions, they can promote innate immune defenses against viral infection...
  30. pmc Role of the cytoplasmic tail domains of Bunyamwera orthobunyavirus glycoproteins Gn and Gc in virus assembly and morphogenesis
    Xiaohong Shi
    Centre for Biomolecular Sciences, School of Biology, University of St Andrews, North Haugh, St Andrews, Scotland, United Kingdom
    J Virol 81:10151-60. 2007
    ..Our results show that the CT domains of both Gn and Gc play crucial roles in BUNV-mediated membrane fusion, virus assembly, and morphogenesis...
  31. ncbi request reprint The mechanism of how anti-IL-18 prevents concanavalin-A-induced hepatic fibrosis on a mouse model
    Yewei Zhang
    The Liver Transplantation Center of the First Affiliated Hospital, Nanjing Medical University, Nanjing, China
    J Surg Res 142:175-83. 2007
    ..The aim of this research was to explore the effects and the mechanisms of IL-18 and anti-IL-18 on hepatic fibrosis in a ConA induced hepatic fibrosis model in BABL-C mice...
  32. pmc Mice with enhanced macrophage angiotensin-converting enzyme are resistant to melanoma
    Xiao Z Shen
    Department of Pathology and Laboratory Medicine, Emory University, 101 Woodruff Circle, Atlanta, GA 30322, USA
    Am J Pathol 170:2122-34. 2007
    ..Injection of B16 tumors with ACE 10/10 macrophages also reduced tumor growth. ACE 10/10 mice may define a new means of enhancing the immune response, which may be potentially useful in several human clinical situations...
  33. ncbi request reprint Resident stem cells are not required for exercise-induced fiber-type switching and angiogenesis but are necessary for activity-dependent muscle growth
    Ping Li
    Department of Medicine, Duke University Medical Center, Independence Park Facility, 4321 Medical Park Dr, Durham, NC 27704, USA
    Am J Physiol Cell Physiol 290:C1461-8. 2006
    ..The origin of the angiogenic cells in this physiological exercise model remains to be determined...
  34. pmc Boosting immune response to hepatitis B DNA vaccine by coadministration of Prothymosin alpha-expressing plasmid
    Yanwen Jin
    P O Box 130 8, 27 Taiping Rd, Beijing 100850, China
    Clin Diagn Lab Immunol 12:1364-9. 2005
    ..Interestingly, administering the DNA separately from the prothymosin alpha plasmid abrogated the enhancement of DNA vaccine potency. The results suggest that prothymosin alpha may be a promising adjuvant for DNA vaccines...
  35. ncbi request reprint Cathepsin E: a novel target for regulation by class II transactivator
    Christina S K Yee
    Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
    J Immunol 172:5528-34. 2004
    ..We found that CatE expression is inducible by PU.1 and p300, and that this induction can be reversed by CIITA. These findings demonstrate a novel phenomenon: regulation of CatE Ag processing by CIITA in an isoform-dependent manner...
  36. ncbi request reprint Bilirubin as a potent antioxidant suppresses experimental autoimmune encephalomyelitis: implications for the role of oxidative stress in the development of multiple sclerosis
    Yingru Liu
    Brain Research Center, University of British Columbia, 2211 Wesbrook Mall, V6T 2B5, Vancouver, BC, Canada
    J Neuroimmunol 139:27-35. 2003
    ..Our results suggest that free radicals play an important role in the final effector stages of EAE, and that antioxidant therapies may have potential for the treatment of MS...
  37. ncbi request reprint Enzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP)
    Anthony J Petrolonis
    Millennium Pharmaceuticals, Inc, Cambridge, Massachusetts 02139, USA
    J Biol Chem 279:13976-83. 2004
    ..IGRP inhibitors may be an attractive new approach for the treatment of insulin secretion defects in type 2 diabetes...
  38. ncbi request reprint Nardosinone, the first enhancer of neurite outgrowth-promoting activity of staurosporine and dibutyryl cyclic AMP in PC12D cells
    Ping Li
    Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Sendai, Aoba 980 8578, Japan
    Brain Res Dev Brain Res 145:177-83. 2003
    ..Nardosinone is the first enhancer of the neuritogenic action of dbcAMP and staurosporine and may become a useful pharmacological tool for studying the mechanism of action of not only NGF but also both the neuritogenic substances...
  39. pmc Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases
    Elaine Y Lin
    Center for Study of Reproductive Biology and Women s Health, Departments of Developmental and Molecular Biology Obstetrics and Gynecology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Am J Pathol 163:2113-26. 2003
    ..An increased leukocytic infiltration was also closely associated with the malignant transition. This study demonstrates that the PyMT mouse model is an excellent one to understand the biology of tumor progression in humans...
  40. ncbi request reprint CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions
    Athena W Wong
    Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Nat Immunol 4:891-8. 2003
    ..Plexin-A1 is not required for peptide binding to MHC. These data indicate involvement of plexin-A1 in T cell-DC interactions but not antigen processing or binding...
  41. ncbi request reprint Identification of interaction between PAI-2 and IRF-3
    Yu Qing Zhang
    Department of Molecular Genetics, Shanghai Medical School of Fudan University Key Laboratory of Molecular Medicine, Ministry of Education, Shanghai 200032, China
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 35:661-5. 2003
    ..These data suggest that IRF-3 may be involved in the apoptosis protection and antiviral function of PAI-2...
  42. ncbi request reprint [Screening of proteins interacting with tTG in HeLa cells]
    Ping Li
    Department of Molecular Genetics, Key Laboratory of Molecular Medicine of Ministry of Education, Shanghai Medical Center of Fudan University, Shanghai 200032, China
    Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) 35:478-82. 2003
    ..These findings suggest that tTG might affect the function of TIAR by a calcium-dependent posttranslational modification and the interaction might possibly be involved in the regulation of cell apoptosis...
  43. ncbi request reprint Interaction among nitric oxide, reactive oxygen species, and antioxidants during endotoxemia-related acute renal failure
    Wei Wang
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
    Am J Physiol Renal Physiol 284:F532-7. 2003
    ..Antioxidant therapy preserved GFR and RBF during endotoxemia. The reversal of this protective effect by inhibition of iNOS suggests the importance of the bioavailability of NO for preservation of renal function during early endotoxemia...
  44. ncbi request reprint Role of disulfide bonds in regulating antigen processing and epitope selection
    Ping Li
    Department of Microbiology and Immunology and Walther Oncology Center, Indiana University School of Medicine, Indianapolis 46202, USA
    J Immunol 169:2444-50. 2002
    ..These studies indicate that disulfide bonds regulate Ag processing both locally and at distant sites, thus influencing epitope selection within the class II pathway...
  45. ncbi request reprint [Inhibition of proliferation of human vascular smooth muscle cells by overexpression of p21 gene]
    Xueli Zhang
    Department of Surgery, Huashan Hospital, Fudan University, Shanghai 200040, China
    Zhonghua Yi Xue Za Zhi 82:696-8. 2002
    ..To observe the apoptosis of human vascular smooth muscle cells (HVSMCs) transfected with p21 gene and investigate its potential mechanism...
  46. ncbi request reprint Effective dosing regimen of 1-aminobenzotriazole for inhibition of antipyrine clearance in guinea pigs and mice using serial sampling
    Suresh K Balani
    Millennium Pharmaceuticals, Inc, 45 Sidney Street, Cambridge, MA 02139, USA
    Drug Metab Dispos 32:1092-5. 2004
    ....
  47. ncbi request reprint Voluntary running induces fiber type-specific angiogenesis in mouse skeletal muscle
    Richard E Waters
    Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Am J Physiol Cell Physiol 287:C1342-8. 2004
    ..These findings suggest that endurance training induces angiogenesis in a subpopulation of type IIb + IId/x fibers before switching to type IIa fibers...
  48. ncbi request reprint Antibody responses against SARS-coronavirus and its nucleocaspid in SARS patients
    Yulin Shi
    Department of Laboratory, General Hospital of Guangzhou, Military Command, 510010, China
    J Clin Virol 31:66-8. 2004
    ..SARS-Cov is the etiologic agent of severe acute respiratory syndrome. An understanding of the antibody responses to the viral components is very important for diagnosis and vaccine development...
  49. ncbi request reprint Hoxa-10 deficiency alters region-specific gene expression and perturbs differentiation of natural killer cells during decidualization
    Mohammad A Rahman
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Dev Biol 290:105-17. 2006
    ..Collectively, the results provide evidence that Hoxa-10 influences a host of genes and cell functions necessary for propagating normal decidual development during the post-implantation period...
  50. ncbi request reprint Selectin inhibitor bimosiamose prolongs survival of kidney allografts by reduction in intragraft production of cytokines and chemokines
    Robert Langer
    Division of Immunology and Organ Transplantation, Department of Surgery, The University of Texas Medical School Houston, 6431 Fannin, Suite 6 240, Houston, TX 77030, USA
    J Am Soc Nephrol 15:2893-901. 2004
    ..Thus, BIMO blocks allograft rejection by reduction of intragraft expression of cytokines and chemokines...
  51. pmc Blocking of monocyte chemoattractant protein-1 during tubulointerstitial nephritis resulted in delayed neutrophil clearance
    Ping Li
    Department of Medicine, Renal and Infectious Disease Sections, Baylor College of Medicine, Houston, TX 77030
    Am J Pathol 167:637-49. 2005
    ..Antagonism of MCP-1 in TIN by Ab or RA may alter the pathological process, most likely through delayed removal of apoptotic neutrophils in the inflammatory loci...
  52. ncbi request reprint Transcriptional profiling in mouse skeletal muscle following a single bout of voluntary running: evidence of increased cell proliferation
    Sangdun Choi
    Division of Biology, California Institute of Technology, Pasadena, CA, USA
    J Appl Physiol 99:2406-15. 2005
    ..These findings suggest that a single bout of voluntary running activates the transcriptional network and promotes adaptive processes in skeletal muscle, including cell proliferation...
  53. ncbi request reprint [Blood vessel tissue engineering: seeding vascular smooth muscle cells and endothelial cells sequentially on biodegradable scaffold in vitro]
    Shao jun Wen
    Central Experiment Unit, Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China
    Zhonghua Yi Xue Za Zhi 85:816-8. 2005
    ..To evaluate the effect of seeding vascular smooth muscle cells and endothelial cells sequentially on biodegradable scaffold in vitro...
  54. ncbi request reprint Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo
    Andy Y Shih
    Kinsmen Laboratory, Department of Psychiatry, Brain Research Center, Vancouver, Canada
    J Biol Chem 280:22925-36. 2005
    ..We conclude that Nrf2 may underlie a feedback system limiting oxidative load during chronic metabolic stress...
  55. ncbi request reprint Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway
    Takayuki Akimoto
    Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Biol Chem 280:19587-93. 2005
    ..These findings suggest that contractile activity-induced activation of the p38 MAPK pathway promotes Pgc-1alpha gene expression and skeletal muscle adaptation...
  56. ncbi request reprint ErbB2 promotes Src synthesis and stability: novel mechanisms of Src activation that confer breast cancer metastasis
    Ming Tan
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Res 65:1858-67. 2005
    ....
  57. ncbi request reprint Interaction between plasminogen activator inhibitor type-2 and pre-mRNA processing factor 8
    Jing Fan
    Department of Molecular Genetics, Shanghai Medical School of Fudan University, Key Laboratory of Molecular Medicine, Ministry of Education, Shanghai 200032, China
    Acta Biochim Biophys Sin (Shanghai) 36:623-8. 2004
    ..PAI-2 could bind PRPF8 C-terminal in both the inside and outside of nuclear. These results suggested that the interaction between these two proteins might not be involved in the apoptosis process...
  58. ncbi request reprint [Studies on IgG antibodies of SARS patients]
    Wei ni Ou
    Beijing Ditan Hospital, Beijing 100011, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 18:51-3. 2004
    ..To investigate the significance of detecting specific serum IgG antibodies in clinical diagnosis of SARS as well as affecting factors...
  59. ncbi request reprint FTY720 suppresses humoral immunity by inhibiting germinal center reaction
    Shuhua Han
    Department of Immunology, Baylor College of Medicine, M929, 1 Baylor Plaza, Houston, TX 77030, USA
    Blood 104:4129-33. 2004
    ..Consistently, FTY720 did not have a significant effect on antibody response to a T-independent antigen. Our results may have important implications in application of FTY720 in immune regulation...
  60. pmc Absence of gamma-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes
    M Azizul Haque
    Department of Microbiology and Immunology, and the Walther Oncology Center, Indiana University School of Medicine, and the Walther Cancer Institute, Indianapolis, IN 46202, USA
    J Exp Med 195:1267-77. 2002
    ..Such disparities in the profile of antigenic epitopes displayed by tumors and bystander APCs may contribute to tumor cell survival in the face of immunological defenses...