Research Topics
| Lei LiSummaryAffiliation: University of Virginia Country: USA Publications
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Detail Information
Publications
Genome-wide transcription analyses in rice using tiling microarraysLei Li
National Institute of Biological Sciences, Zhongguancun Life Science Park, Beijing 102206, China
Nat Genet 38:124-9. 2006..Collectively, our results provide the first whole-genome transcription map useful for further understanding the rice genome...
Transcriptional analysis of highly syntenic regions between Medicago truncatula and Glycine max using tiling microarraysLei Li
Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA
Genome Biol 9:R57. 2008..The unprecedented complexity and impending completeness of these data create opportunities for new approaches to discovery...
A pilot study of transcription unit analysis in rice using oligonucleotide tiling-path microarrayViktor Stolc
Department of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA
Plant Mol Biol 59:137-49. 2005..These preliminary results demonstrate the utility of genome tiling microarrays in evaluating annotated rice gene models and in identifying novel transcription units that will facilitate rice genome annotation...
Global identification and characterization of transcriptionally active regions in the rice genomeLei Li
Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States of America
PLoS ONE 2:e294. 2007..These results provide a systematic characterization of non-exonic transcripts in rice and thus expand the current view of the complexity and dynamics of the rice transcriptome...
Tiling microarray analysis of rice chromosome 10 to identify the transcriptome and relate its expression to chromosomal architectureLei Li
Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA
Genome Biol 6:R52. 2005..Experimental evaluation of these gene models and identification of new models will facilitate rice genome annotation and the application of this knowledge to other more complex cereal genomes...
Transcriptionally active gene fragments derived from potentially fast-evolving donor genes in the rice genomeXiangfeng Wang
Department of Molecular, Cell and Developmental Biology, Yale University, New Haven, CT 06520, USA
Bioinformatics 25:1215-8. 2009..Our results demonstrated a large number of actively TGFs in the rice genome and shed light on the origin, mode of action and function of the TGFs...
A tiling microarray expression analysis of rice chromosome 4 suggests a chromosome-level regulation of transcriptionYuling Jiao
Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Conecticut 06520-8014, USA
Plant Cell 17:1641-57. 2005..These results suggest a close correlation between transcriptional activity and chromosome organization and the developmental regulation of transcription activity at the chromosome level...
Genome-wide mapping of the HY5-mediated gene networks in Arabidopsis that involve both transcriptional and post-transcriptional regulationHuiyong Zhang
Peking Yale Joint Center of Plant Molecular Genetics and Agrobiotechnology, National Laboratory of Protein Engineering and Plant Genetic Engineering, School of Life Sciences, Peking University, Beijing 100871, China
Plant J 65:346-58. 2011..Over-expressing HY5-targeted miR408 resulted in phenotypes that are opposite to the hy5 mutants. Together, our results reveal both transcriptional and post-transcriptional components of the HY5-mediated gene networks...
It runs in the family: regulation of brassinosteroid signaling by the BZR1-BES1 class of transcription factorsLei Li
Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520-8104, USA
Trends Plant Sci 10:266-8. 2005....
Maintenance of the flip sequence orientation of the ears in the parvoviral left-end hairpin is a nonessential consequence of the critical asymmetry in the hairpin stemLei Li
Department of Laboratory Medicine, Yale University Medical School, New Haven, Connecticut, USA
J Virol 86:12187-97. 2012..In contrast, both sequence and orientation changes in the hairpin ears were tolerated, suggesting that maintaining the Flip orientation of these structures is a consequence of, but not the reason for, asymmetric left-end processing...
Distinct reorganization of the genome transcription associates with organogenesis of somatic embryo, shoots, and roots in riceNing Su
Peking Yale Joint Center of Plant Molecular Genetics and Agrobiotechnology, College of Life Sciences, Peking University, Beijing 100871, China
Plant Mol Biol 63:337-49. 2007..Comparison of these three transcriptomes revealed little overlap during these three organogenesis processes. These results indicate that each organogenesis involves specific reorganization of genome expression...
NMPP: a user-customized NimbleGen microarray data processing pipelineXiangfeng Wang
Center of Bioinformatics and Peking Yale Joint Research Center of Plant Molecular Genetics and Agrobiotechnology, College of Life Sciences, Peking University, Beijing 100871, China
Bioinformatics 22:2955-7. 2006..AVAILABILITY: http://plantgenomics.biology.yale.edu/nmpp..
Protein/DNA arrays identify nitric oxide-regulated cis-element and trans-factor activities some of which govern neuroblastoma cell viabilitySaravanakumar Dhakshinamoorthy
Cell Death and Human Diseases Group, Division of Genomics and Genetics, Institute of Molecular and Cell Biology, Proteos, 61 Biopolis Drive, Singapore 138673, Republic of Singapore
Nucleic Acids Res 35:5439-51. 2007..Our results emphasize that a DNA/protein array approach can reveal novel, global transcription factor activities stimulated by cell death-regulating molecules...
Maternally derived FILIA-MATER complex localizes asymmetrically in cleavage-stage mouse embryosMami Ohsugi
Laboratory of Cellular and Developmental Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
Development 135:259-69. 2008..If so, the plasticity of the FILIA-MATER complex localization may reflect the regulative nature of preimplantation mouse development...
Modulation of brassinosteroid-regulated gene expression by Jumonji domain-containing proteins ELF6 and REF6 in ArabidopsisXiaofei Yu
Department of Genetics, Development and Cell Biology, Plant Science Institute, Iowa State University, Ames, IA 50011, USA
Proc Natl Acad Sci U S A 105:7618-23. 2008..Thus, our study establishes an important mechanism by which Jmj domain proteins modulate specific gene expression by interacting with pathway-specific transcription factors such as BES1...
A modular analysis framework for blood genomics studies: application to systemic lupus erythematosusDamien Chaussabel
Baylor NIAID Cooperative Center for Translational Research on Human Immunology and Biodefense, Baylor Institute for Immunology Research and Baylor Research Institute, Dallas, TX 75204, USA
Immunity 29:150-64. 2008..Thus, this work describes the implementation and application of a methodology designed to support systems-scale analysis of the human immune system in translational research settings...
Evolutionary expansion, gene structure, and expression of the rice wall-associated kinase gene familyShibo Zhang
Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
Plant Physiol 139:1107-24. 2005..Localized gene duplications appear to be the primary genetic event in OsWAK gene family expansion and the 125 OsWAKs, present on all 12 chromosomes, are mostly clustered...
The tomato homolog of CORONATINE-INSENSITIVE1 is required for the maternal control of seed maturation, jasmonate-signaled defense responses, and glandular trichome developmentLei Li
Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
Plant Cell 16:126-43. 2004..These findings indicate that the JA/COI1 signaling pathway regulates distinct developmental processes in different plants and suggest a role for JA in the promotion of glandular trichome-based defenses...
[The use of gene expression differential display analysis technics in trauma research]Fa-Liang Xu
Institute of Military Surgery, Third Military Medical University, Chongqing 400042
Sheng Li Ke Xue Jin Zhan 33:322-6. 2002..These methods have been widely used in the research of tumor and other disease. This review will focus to some usage of the ways in traumatology...
