Lei Li

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi request reprint Genome-wide transcription analyses in rice using tiling microarrays
    Lei Li
    National Institute of Biological Sciences, Zhongguancun Life Science Park, Beijing 102206, China
    Nat Genet 38:124-9. 2006
  2. pmc Transcriptional analysis of highly syntenic regions between Medicago truncatula and Glycine max using tiling microarrays
    Lei Li
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Genome Biol 9:R57. 2008
  3. pmc Global identification and characterization of transcriptionally active regions in the rice genome
    Lei Li
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States of America
    PLoS ONE 2:e294. 2007
  4. ncbi request reprint A pilot study of transcription unit analysis in rice using oligonucleotide tiling-path microarray
    Viktor Stolc
    Department of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Plant Mol Biol 59:137-49. 2005
  5. pmc Tiling microarray analysis of rice chromosome 10 to identify the transcriptome and relate its expression to chromosomal architecture
    Lei Li
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Genome Biol 6:R52. 2005
  6. doi request reprint Transcriptionally active gene fragments derived from potentially fast-evolving donor genes in the rice genome
    Xiangfeng Wang
    Department of Molecular, Cell and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Bioinformatics 25:1215-8. 2009
  7. pmc A tiling microarray expression analysis of rice chromosome 4 suggests a chromosome-level regulation of transcription
    Yuling Jiao
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Conecticut 06520 8014, USA
    Plant Cell 17:1641-57. 2005
  8. pmc Toll-like receptor 9 in plasmacytoid dendritic cells fails to detect parvoviruses
    Lisa M Mattei
    Department of Immunobiology, Yale University, New Haven, CT, USA
    J Virol 87:3605-8. 2013
  9. doi request reprint Genome-wide mapping of the HY5-mediated gene networks in Arabidopsis that involve both transcriptional and post-transcriptional regulation
    Huiyong Zhang
    Peking Yale Joint Center of Plant Molecular Genetics and Agrobiotechnology, National Laboratory of Protein Engineering and Plant Genetic Engineering, School of Life Sciences, Peking University, Beijing 100871, China
    Plant J 65:346-58. 2011
  10. ncbi request reprint It runs in the family: regulation of brassinosteroid signaling by the BZR1-BES1 class of transcription factors
    Lei Li
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520 8104, USA
    Trends Plant Sci 10:266-8. 2005

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Genome-wide transcription analyses in rice using tiling microarrays
    Lei Li
    National Institute of Biological Sciences, Zhongguancun Life Science Park, Beijing 102206, China
    Nat Genet 38:124-9. 2006
    ..Collectively, our results provide the first whole-genome transcription map useful for further understanding the rice genome...
  2. pmc Transcriptional analysis of highly syntenic regions between Medicago truncatula and Glycine max using tiling microarrays
    Lei Li
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Genome Biol 9:R57. 2008
    ..The unprecedented complexity and impending completeness of these data create opportunities for new approaches to discovery...
  3. pmc Global identification and characterization of transcriptionally active regions in the rice genome
    Lei Li
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Connecticut, United States of America
    PLoS ONE 2:e294. 2007
    ..These results provide a systematic characterization of non-exonic transcripts in rice and thus expand the current view of the complexity and dynamics of the rice transcriptome...
  4. ncbi request reprint A pilot study of transcription unit analysis in rice using oligonucleotide tiling-path microarray
    Viktor Stolc
    Department of Molecular Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Plant Mol Biol 59:137-49. 2005
    ..These preliminary results demonstrate the utility of genome tiling microarrays in evaluating annotated rice gene models and in identifying novel transcription units that will facilitate rice genome annotation...
  5. pmc Tiling microarray analysis of rice chromosome 10 to identify the transcriptome and relate its expression to chromosomal architecture
    Lei Li
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Genome Biol 6:R52. 2005
    ..Experimental evaluation of these gene models and identification of new models will facilitate rice genome annotation and the application of this knowledge to other more complex cereal genomes...
  6. doi request reprint Transcriptionally active gene fragments derived from potentially fast-evolving donor genes in the rice genome
    Xiangfeng Wang
    Department of Molecular, Cell and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Bioinformatics 25:1215-8. 2009
    ..Our results demonstrated a large number of actively TGFs in the rice genome and shed light on the origin, mode of action and function of the TGFs...
  7. pmc A tiling microarray expression analysis of rice chromosome 4 suggests a chromosome-level regulation of transcription
    Yuling Jiao
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, Conecticut 06520 8014, USA
    Plant Cell 17:1641-57. 2005
    ..These results suggest a close correlation between transcriptional activity and chromosome organization and the developmental regulation of transcription activity at the chromosome level...
  8. pmc Toll-like receptor 9 in plasmacytoid dendritic cells fails to detect parvoviruses
    Lisa M Mattei
    Department of Immunobiology, Yale University, New Haven, CT, USA
    J Virol 87:3605-8. 2013
    ..Here we have shown that despite the ability of purified genomic DNA to stimulate TLR9 and despite the ability to enter TLR9 endosomes, ssDNA viruses of the Parvoviridae family failed to elicit an interferon (IFN) response in pDCs...
  9. doi request reprint Genome-wide mapping of the HY5-mediated gene networks in Arabidopsis that involve both transcriptional and post-transcriptional regulation
    Huiyong Zhang
    Peking Yale Joint Center of Plant Molecular Genetics and Agrobiotechnology, National Laboratory of Protein Engineering and Plant Genetic Engineering, School of Life Sciences, Peking University, Beijing 100871, China
    Plant J 65:346-58. 2011
    ..Over-expressing HY5-targeted miR408 resulted in phenotypes that are opposite to the hy5 mutants. Together, our results reveal both transcriptional and post-transcriptional components of the HY5-mediated gene networks...
  10. ncbi request reprint It runs in the family: regulation of brassinosteroid signaling by the BZR1-BES1 class of transcription factors
    Lei Li
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520 8104, USA
    Trends Plant Sci 10:266-8. 2005
    ....
  11. pmc The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability
    Jin Na Min
    Department of Laboratory Medicine and Pathology, Yale University School of Medicine, New Haven, CT 06520, USA
    Cell Res 23:1396-413. 2013
    ..Our studies suggest that the mIno80 chromatin remodeling complex plays important roles in telomere replication, HDR-mediated repair of dysfunctional telomeres, and maintenance of genome stability...
  12. pmc Maintenance of the flip sequence orientation of the ears in the parvoviral left-end hairpin is a nonessential consequence of the critical asymmetry in the hairpin stem
    Lei Li
    Department of Laboratory Medicine, Yale University Medical School, New Haven, Connecticut, USA
    J Virol 86:12187-97. 2012
    ..In contrast, both sequence and orientation changes in the hairpin ears were tolerated, suggesting that maintaining the Flip orientation of these structures is a consequence of, but not the reason for, asymmetric left-end processing...
  13. ncbi request reprint Distinct reorganization of the genome transcription associates with organogenesis of somatic embryo, shoots, and roots in rice
    Ning Su
    Peking Yale Joint Center of Plant Molecular Genetics and Agrobiotechnology, College of Life Sciences, Peking University, Beijing 100871, China
    Plant Mol Biol 63:337-49. 2007
    ..Comparison of these three transcriptomes revealed little overlap during these three organogenesis processes. These results indicate that each organogenesis involves specific reorganization of genome expression...
  14. pmc The tomato homolog of CORONATINE-INSENSITIVE1 is required for the maternal control of seed maturation, jasmonate-signaled defense responses, and glandular trichome development
    Lei Li
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824, USA
    Plant Cell 16:126-43. 2004
    ..These findings indicate that the JA/COI1 signaling pathway regulates distinct developmental processes in different plants and suggest a role for JA in the promotion of glandular trichome-based defenses...
  15. pmc Evolutionary expansion, gene structure, and expression of the rice wall-associated kinase gene family
    Shibo Zhang
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Plant Physiol 139:1107-24. 2005
    ..Localized gene duplications appear to be the primary genetic event in OsWAK gene family expansion and the 125 OsWAKs, present on all 12 chromosomes, are mostly clustered...
  16. pmc A modular analysis framework for blood genomics studies: application to systemic lupus erythematosus
    Damien Chaussabel
    Baylor NIAID Cooperative Center for Translational Research on Human Immunology and Biodefense, Baylor Institute for Immunology Research and Baylor Research Institute, Dallas, TX 75204, USA
    Immunity 29:150-64. 2008
    ..Thus, this work describes the implementation and application of a methodology designed to support systems-scale analysis of the human immune system in translational research settings...
  17. pmc Modulation of brassinosteroid-regulated gene expression by Jumonji domain-containing proteins ELF6 and REF6 in Arabidopsis
    Xiaofei Yu
    Department of Genetics, Development and Cell Biology, Plant Science Institute, Iowa State University, Ames, IA 50011, USA
    Proc Natl Acad Sci U S A 105:7618-23. 2008
    ..Thus, our study establishes an important mechanism by which Jmj domain proteins modulate specific gene expression by interacting with pathway-specific transcription factors such as BES1...
  18. ncbi request reprint NMPP: a user-customized NimbleGen microarray data processing pipeline
    Xiangfeng Wang
    Center of Bioinformatics and Peking Yale Joint Research Center of Plant Molecular Genetics and Agrobiotechnology, College of Life Sciences, Peking University, Beijing 100871, China
    Bioinformatics 22:2955-7. 2006
    ....
  19. ncbi request reprint Maternally derived FILIA-MATER complex localizes asymmetrically in cleavage-stage mouse embryos
    Mami Ohsugi
    Laboratory of Cellular and Developmental Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA
    Development 135:259-69. 2008
    ..If so, the plasticity of the FILIA-MATER complex localization may reflect the regulative nature of preimplantation mouse development...
  20. pmc Protein/DNA arrays identify nitric oxide-regulated cis-element and trans-factor activities some of which govern neuroblastoma cell viability
    Saravanakumar Dhakshinamoorthy
    Cell Death and Human Diseases Group, Division of Genomics and Genetics, Institute of Molecular and Cell Biology, Proteos, 61 Biopolis Drive, Singapore 138673, Republic of Singapore
    Nucleic Acids Res 35:5439-51. 2007
    ..Our results emphasize that a DNA/protein array approach can reveal novel, global transcription factor activities stimulated by cell death-regulating molecules...
  21. ncbi request reprint [The use of gene expression differential display analysis technics in trauma research]
    Fa Liang Xu
    Institute of Military Surgery, Third Military Medical University, Chongqing 400042
    Sheng Li Ke Xue Jin Zhan 33:322-6. 2002
    ..These methods have been widely used in the research of tumor and other disease. This review will focus to some usage of the ways in traumatology...