JAMES YH LI

Summary

Affiliation: University of Connecticut Health Center
Country: USA

Publications

  1. ncbi New regulatory interactions and cellular responses in the isthmic organizer region revealed by altering Gbx2 expression
    James Y H Li
    Howard Hughes Medical Institute and Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA
    Development 132:1971-81. 2005
  2. ncbi Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer
    James Y H Li
    Howard Hughes Medical Institute and Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, New York, NY 10016, USA
    Neuron 36:31-43. 2002
  3. ncbi FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors
    Aimin Liu
    Howard Hughes Medical Institute, Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Development 130:6175-85. 2003
  4. ncbi Distinct functions of the major Fgf8 spliceform, Fgf8b, before and during mouse gastrulation
    Qiuxia Guo
    Department of Genetics and Developmental Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA
    Development 134:2251-60. 2007
  5. ncbi General method for the modification of different BAC types and the rapid generation of BAC transgenic mice
    Tim Sparwasser
    Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany
    Genesis 38:39-50. 2004

Research Grants

  1. Role of Gbx2 and Otx2 in the mes-met organizer function
    James Li; Fiscal Year: 2003
  2. The Role of Alternative Splicing of Fgf8 in Mouse Development
    James Li; Fiscal Year: 2007
  3. The Role of Alternative Splicing of Fgf8 in Mouse Development
    James Y H Li; Fiscal Year: 2010

Collaborators

Detail Information

Publications5

  1. ncbi New regulatory interactions and cellular responses in the isthmic organizer region revealed by altering Gbx2 expression
    James Y H Li
    Howard Hughes Medical Institute and Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA
    Development 132:1971-81. 2005
    ..Our studies provide new insights into the regulatory interactions that maintain isthmic organizer gene expression and the consequences of altered levels of organizer gene expression on cell survival...
  2. ncbi Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer
    James Y H Li
    Howard Hughes Medical Institute and Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, New York, NY 10016, USA
    Neuron 36:31-43. 2002
    ..Our work has uncovered distinct requirements for Gbx2 during cerebellum formation and provided a model for how a transcription factor can play multiple roles during development...
  3. ncbi FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors
    Aimin Liu
    Howard Hughes Medical Institute, Developmental Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Development 130:6175-85. 2003
    ..As Fgf17 and Fgf18 are co-expressed with Fgf8 in many tissues, our studies have broad implications for how these FGFs differentially control development...
  4. ncbi Distinct functions of the major Fgf8 spliceform, Fgf8b, before and during mouse gastrulation
    Qiuxia Guo
    Department of Genetics and Developmental Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030, USA
    Development 134:2251-60. 2007
    ....
  5. ncbi General method for the modification of different BAC types and the rapid generation of BAC transgenic mice
    Tim Sparwasser
    Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany
    Genesis 38:39-50. 2004
    ..Altogether, using a combination of genomic database analysis, overlap PCR cloning, and BAC recombination in bacteria, our approach allows for the rapid and reliable generation of "pseudo knockin" mice. genesis 38:39-50, 2004...

Research Grants5

  1. Role of Gbx2 and Otx2 in the mes-met organizer function
    James Li; Fiscal Year: 2003
    ..abstract_text> ..
  2. The Role of Alternative Splicing of Fgf8 in Mouse Development
    James Li; Fiscal Year: 2007
    ..Therefore, our proposed studies should shed light on abnormal regulation of Fgf8 splicing on pathological conditions, including tumor formation in human. ..
  3. The Role of Alternative Splicing of Fgf8 in Mouse Development
    James Y H Li; Fiscal Year: 2010
    ..Therefore, our proposed studies should shed light on abnormal regulation of Fgf8 splicing on pathological conditions, including tumor formation in human. ..