Research Topics
| Mark H LewisSummaryAffiliation: University of Florida Country: USA Publications
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Detail Information
Publications
Animal models of restricted repetitive behavior in autismMark H Lewis
McKnight Brain Institute and Department of Psychiatry, University of Florida, Gainesville, FL 32610, USA
Behav Brain Res 176:66-74. 2007..As mutant mouse models continue to proliferate, there should be a number of promising genetic models to pursue...- Environmental complexity and central nervous system development and functionMark H Lewis
McKnight Brain Institute and Department of Psychiatry, University of Florida, Gainesville, Florida 32601, USA
Ment Retard Dev Disabil Res Rev 10:91-5. 2004..These effects were not observed in limbic areas such as the hippocampus... 
Procedural learning and cognitive flexibility in a mouse model of restricted, repetitive behaviourYoko Tanimura
McKnight Brain Institute, Department of Psychiatry and Psychology, University of Florida, Gainesville, FL, USA
Behav Brain Res 189:250-6. 2008..Our findings support the applicability of the deer mouse model of spontaneous stereotypy to a wider range of restricted, repetitive behaviour (e.g., insistence on sameness) typical of neurodevelopmental disorders...
Indirect basal ganglia pathway mediation of repetitive behavior: attenuation by adenosine receptor agonistsYoko Tanimura
Departments of Psychiatry and Psychology, McKnight Brain Institute, University of Florida, Gainesville, FL, United States
Behav Brain Res 210:116-22. 2010....- Amphetamine-induced sensitization and spontaneous stereotypy in deer miceYoko Tanimura
Department of Psychiatry and McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA
Pharmacol Biochem Behav 92:670-5. 2009..Thus, the present findings do not support the notion that sensitization-related neuroadaptations in cortical-basal ganglia circuitry are similar to those neuroadaptations that underlie spontaneous or environmentally linked stereotypy... - Development of repetitive behavior in a mouse model: roles of indirect and striosomal basal ganglia pathwaysYoko Tanimura
Department of Psychology, McKnight Brain Institute, University of Florida, Gainesville, FL 32611, USA
Int J Dev Neurosci 29:461-7. 2011..Our results point to dynamic changes in the indirect pathway associated with the development of repetitive behavior and extends our prior work linking reduced indirect pathway activation to stereotypy in adult deer mice... - Effects of intrastriatal administration of selective dopaminergic ligands on spontaneous stereotypy in miceMichael F Presti
Department of Neuroscience, University of Florida, 100 S. Newell Drive, P.O. Box 100256, Gainesville, FL 32610-0256, USA
Physiol Behav 80:433-9. 2004.... - Environmental enrichment: effects on stereotyped behavior and dendritic morphologyCortney A Turner
McKnight Brain Institute and Department of Psychiatry, University of Florida, Gainesville, FL 32601, USA
Dev Psychobiol 43:20-7. 2003..These results suggest that the enrichment-related prevention of stereotyped behavior is associated with increased dendritic spine density... - Behavior-related alterations of striatal neurochemistry in a mouse model of stereotyped movement disorderMichael F Presti
Department of Neuroscience, University of Florida, Gainesville, FL 32610, USA
Pharmacol Biochem Behav 77:501-7. 2004..Moreover, the present findings demonstrate the usefulness of the microdialysis system employed in studying the neurochemical substrates of rapidly transitioning behavior... - Striatal opioid peptide content in an animal model of spontaneous stereotypic behaviorMichael F Presti
Department of Psychiatry, University of Florida, 100 S Newell Dr, P O Box 100256, Gainesville, FL 32610, USA
Behav Brain Res 157:363-8. 2005.... - Environmental enrichment: effects on stereotyped behavior and regional neuronal metabolic activityCortney A Turner
Department of Psychiatry, P.O. Box 100256, University of Florida, Gainesville, FL 32601, USA
Brain Res 938:15-21. 2002..These results suggest that, in a developmental model of spontaneous stereotypy, the enrichment-related prevention of stereotyped behavior is associated with increased CO activity... - Effects of access to voluntary wheel running on the development of stereotypyArtur Pawlowicz
Department of Psychiatry and McKnight Brain Institute, University of Florida, Gainesville, FL 32611, USA
Behav Processes 83:242-6. 2010..Thus, exercise alone, unlike environmental enrichment, does not prevent the development of stereotypy. These results have important implications for animal welfare... - Development and temporal organization of repetitive behavior in an animal modelYoko Tanimura
Departments of Psychiatry and Psychology, McKnight Brain Institute, University of Florida, 100 S Newell Drive, Gainesville, FL 32611, USA
Dev Psychobiol 52:813-24. 2010..Such methods may be useful tools in the assessment and treatment of repetitive behavior in clinical populations... - Effects of topiramate in adults with Prader-Willi syndromeNathan A Shapira
College of Medicine, University of Florida, Gainesville 32610, USA
Am J Ment Retard 109:301-9. 2004..e., skin-picking) that is characteristic of this syndrome. Potential benefits of topiramate for self-injury should be evaluated further in controlled trials... - Selective blockade of spontaneous motor stereotypy via intrastriatal pharmacological manipulationMichael F Presti
Department of Neuroscience, University of Florida, 100 South Newell Drive, PO Box 100256, Gainesville, FL 32610-0256, USA
Pharmacol Biochem Behav 74:833-9. 2003..These findings support the hypothesis that environmentally related stereotypy is expressed as a consequence of elevated feedback activity occurring along motor circuits of the basal ganglia... - Dissociation between spontaneously emitted and apomorphine-induced stereotypy in Peromyscus maniculatus bairdiiMichael F Presti
Department of Psychiatry, University of Florida, 100 South Newell Drive, PO Box 100256, Gainesville, FL 32610, USA
Physiol Behav 75:347-53. 2002..The results obtained do provide support, however, for a limited involvement of the DA system in the mediation of these behaviors... - D-cycloserine does not enhance exposure-response prevention therapy in obsessive-compulsive disorderEric A Storch
Departments of Psychiatry, University of Florida, Florida 32610, USA
Int Clin Psychopharmacol 22:230-7. 2007..As this study is the first to explore this question and a number of methodological issues must be considered when interpreting the findings, the conclusions that may be drawn from our results are limited... - Detecting pediatric autoimmune neuropsychiatric disorders associated with streptococcus in children with obsessive-compulsive disorder and ticsTanya K Murphy
Department of Psychiatry, University of Florida, Gainesville, Florida 32610-0256, USA
Biol Psychiatry 55:61-8. 2004..03). CONCLUSIONS: Patients with marked obsessive-compulsive/tic symptom changes may be characterized by streptococcal titer elevations and exhibit evidence of seasonal tic exacerbations... - Environmental enrichment: effects on stereotyped behavior and neurotrophin levelsCortney A Turner
Mental Health Research Institute, University of Michigan, 205 Zina Pitcher Place, Ann Arbor, MI 48109, USA
Physiol Behav 80:259-66. 2003..There were no differences in NGF in the striatum. These results provide evidence that the enrichment-related prevention of stereotyped behavior in deer mice is associated with increased BDNF in the striatum...