Alexandra M Levine

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi request reprint AIDS-related lymphoma
    Alexandra M Levine
    Division of Hematology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Semin Oncol Nurs 22:80-9. 2006
  2. ncbi request reprint Liposome-encapsulated doxorubicin in combination with standard agents (cyclophosphamide, vincristine, prednisone) in patients with newly diagnosed AIDS-related non-Hodgkin's lymphoma: results of therapy and correlates of response
    Alexandra M Levine
    Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    J Clin Oncol 22:2662-70. 2004
  3. ncbi request reprint Progressive prothrombotic state in women with advancing HIV disease
    Alexandra M Levine
    Department of Medicine, Division of Hematology, Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA
    J Acquir Immune Defic Syndr 42:572-7. 2006
  4. ncbi request reprint Phase I study of antisense oligonucleotide against vascular endothelial growth factor: decrease in plasma vascular endothelial growth factor with potential clinical efficacy
    Alexandra M Levine
    Department of Medicine, University of Southern California USC, Keck School of Medicine, Los Angeles, CA 90033, USA
    J Clin Oncol 24:1712-9. 2006
  5. ncbi request reprint Neutropenia in human immunodeficiency virus infection: data from the women's interagency HIV study
    Alexandra M Levine
    Department of Medicine, Division of Hematology, University of Southern California, Los Angeles, CA 90033, USA
    Arch Intern Med 166:405-10. 2006
  6. doi request reprint Efficacy of epoetin alfa administered every 2 weeks to maintain hemoglobin and quality of life in anemic HIV-infected patients
    Alexandra M Levine
    City of Hope National Medical Center, 1500 Duarte Road, Duarte, California 91010, USA
    AIDS Res Hum Retroviruses 24:131-9. 2008
  7. ncbi request reprint AIDS-related Burkitt's lymphoma versus diffuse large-cell lymphoma in the pre-highly active antiretroviral therapy (HAART) and HAART eras: significant differences in survival with standard chemotherapy
    Soon Thye Lim
    Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    J Clin Oncol 23:4430-8. 2005
  8. doi request reprint Association of cells with natural killer (NK) and NKT immunophenotype with incident cancers in HIV-infected women
    Marek J Nowicki
    Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    AIDS Res Hum Retroviruses 24:163-8. 2008
  9. ncbi request reprint Impact of highly active antiretroviral therapy on anemia and relationship between anemia and survival in a large cohort of HIV-infected women: Women's Interagency HIV Study
    Kiros Berhane
    Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9011, USA
    J Acquir Immune Defic Syndr 37:1245-52. 2004
  10. ncbi request reprint Phase I/II trial of nonpegylated liposomal doxorubicin, cyclophosphamide, vincristine, and prednisone in the treatment of newly diagnosed aggressive non-Hodgkin's lymphoma
    Anil Tulpule
    Division of Hematology, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
    Clin Lymphoma Myeloma 7:59-64. 2006

Research Grants

  1. AIDS ASSOCIATED MALIGNANCIES CLINICAL TRIALS CONSORTIUM
    Alexandra Levine; Fiscal Year: 2005
  2. WOMEN'S INTERAGENCY HIV STUDY
    Alexandra Levine; Fiscal Year: 2007

Detail Information

Publications77

  1. ncbi request reprint AIDS-related lymphoma
    Alexandra M Levine
    Division of Hematology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Semin Oncol Nurs 22:80-9. 2006
    ..To review the epidemiology, pathology, clinical features, prognostic factors, and treatment approaches of patients with AIDS-related lymphoma...
  2. ncbi request reprint Liposome-encapsulated doxorubicin in combination with standard agents (cyclophosphamide, vincristine, prednisone) in patients with newly diagnosed AIDS-related non-Hodgkin's lymphoma: results of therapy and correlates of response
    Alexandra M Levine
    Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    J Clin Oncol 22:2662-70. 2004
    ..Secondary objectives were to assess the impact of HIV viral control on response and survival, and to correlate MDR-1 expression with outcome...
  3. ncbi request reprint Progressive prothrombotic state in women with advancing HIV disease
    Alexandra M Levine
    Department of Medicine, Division of Hematology, Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA
    J Acquir Immune Defic Syndr 42:572-7. 2006
    ..HIV-infected patients are at increased risk for venous thrombotic events (VTEs). We sought to determine if advancing stages of HIV were associated with coagulation abnormalities that could predispose to VTE...
  4. ncbi request reprint Phase I study of antisense oligonucleotide against vascular endothelial growth factor: decrease in plasma vascular endothelial growth factor with potential clinical efficacy
    Alexandra M Levine
    Department of Medicine, University of Southern California USC, Keck School of Medicine, Los Angeles, CA 90033, USA
    J Clin Oncol 24:1712-9. 2006
    ..This study established the safety, biologic effects, and pharmacokinetics of VEGF-AS in 51 patients with advanced malignancies...
  5. ncbi request reprint Neutropenia in human immunodeficiency virus infection: data from the women's interagency HIV study
    Alexandra M Levine
    Department of Medicine, Division of Hematology, University of Southern California, Los Angeles, CA 90033, USA
    Arch Intern Med 166:405-10. 2006
    ..Neither the effect of highly active antiretroviral therapy (HAART) on neutrophil counts nor the significance of neutropenia in terms of survival has previously been evaluated...
  6. doi request reprint Efficacy of epoetin alfa administered every 2 weeks to maintain hemoglobin and quality of life in anemic HIV-infected patients
    Alexandra M Levine
    City of Hope National Medical Center, 1500 Duarte Road, Duarte, California 91010, USA
    AIDS Res Hum Retroviruses 24:131-9. 2008
    ....
  7. ncbi request reprint AIDS-related Burkitt's lymphoma versus diffuse large-cell lymphoma in the pre-highly active antiretroviral therapy (HAART) and HAART eras: significant differences in survival with standard chemotherapy
    Soon Thye Lim
    Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    J Clin Oncol 23:4430-8. 2005
    ....
  8. doi request reprint Association of cells with natural killer (NK) and NKT immunophenotype with incident cancers in HIV-infected women
    Marek J Nowicki
    Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    AIDS Res Hum Retroviruses 24:163-8. 2008
    ..HIV-induced innate immune dysfunction may contribute to the eventual emergence of cancer in the setting of existing coinfections and altered immunosurveillance...
  9. ncbi request reprint Impact of highly active antiretroviral therapy on anemia and relationship between anemia and survival in a large cohort of HIV-infected women: Women's Interagency HIV Study
    Kiros Berhane
    Keck School of Medicine, University of Southern California, Los Angeles, CA 90089 9011, USA
    J Acquir Immune Defic Syndr 37:1245-52. 2004
    ..Anemia is common in HIV-infected individuals and may be associated with decreased survival...
  10. ncbi request reprint Phase I/II trial of nonpegylated liposomal doxorubicin, cyclophosphamide, vincristine, and prednisone in the treatment of newly diagnosed aggressive non-Hodgkin's lymphoma
    Anil Tulpule
    Division of Hematology, Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
    Clin Lymphoma Myeloma 7:59-64. 2006
    ..Liposomal doxorubicin at doses of 40 mg/m2, 50 mg/m2, 60 mg/m2, and 80 mg/m2 was given with fixed doses of cyclophosphamide, vincristine, and prednisone. Chemotherapy cycles were repeated every 21 days...
  11. pmc Interleukin 10 responses are associated with sustained CD4 T-cell counts in treated HIV infection
    Maria C Villacres
    Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Infect Dis 206:780-9. 2012
    ..We investigated the correlation of cytokine responses with changes in CD4 T-cell levels and coinfection with hepatitis C virus (HCV) during highly active antiretroviral treatment (HAART)...
  12. ncbi request reprint Correlates of prevalent hypertension in a large cohort of HIV-infected women: Women's Interagency HIV Study
    Ann Khalsa
    University of Southern California, Los Angeles, California, USA
    AIDS 21:2539-41. 2007
    ..0001), and body mass index greater than 30 kg/m (P < 0.0001), whereas current pregnancy was protective (P < 0.04). HIV infection, CD4 cell count, HIV-1 viral load, and antiretroviral therapy were not associated with hypertension...
  13. pmc HIV as a risk factor for lung cancer in women: data from the Women's Interagency HIV Study
    Alexandra M Levine
    City of Hope National Medical Center, Duarte, CA 91010, USA
    J Clin Oncol 28:1514-9. 2010
    ..We sought to determine the role of HIV infection and highly active antiretroviral therapy (HAART) on lung cancer incidence in 2,651 HIV-infected and 898 HIV-uninfected women from the Women's Interagency HIV Study (WIHS)...
  14. pmc Pegylated liposomal doxorubicin, rituximab, cyclophosphamide, vincristine, and prednisone in AIDS-related lymphoma: AIDS Malignancy Consortium Study 047
    Alexandra M Levine
    City of Hope National Medical Center, Duarte, CA 91010, USA
    J Clin Oncol 31:58-64. 2013
    ....
  15. pmc Antiretroviral therapy exposure and insulin resistance in the Women's Interagency HIV study
    Phyllis C Tien
    Department of Medicine, University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Acquir Immune Defic Syndr 49:369-76. 2008
    ....
  16. pmc Factors associated with prevalent hepatitis C infection among HIV-infected women with no reported history of injection drug use: the Women's Interagency HIV Study (WIHS)
    Toni Frederick
    Maternal Child and Adolescent Center for Infectious Diseases and Virology, University of Southern California, Los Angeles, California, USA
    AIDS Patient Care STDS 23:915-23. 2009
    ..25). For HIV-positive women with no reported history of IDU, sex with an IDU male was independently associated with HCV suggesting that sexual transmission may be an important mode of HCV transmission for these high-risk women...
  17. ncbi request reprint Cancer risk among participants in the women's interagency HIV study
    Nancy A Hessol
    Department of Medicine, University of California, San Francisco, 94122, USA
    J Acquir Immune Defic Syndr 36:978-85. 2004
    ..The HIV epidemic has been associated with an increased incidence of specific cancers. However, less is known about cancers occurring in HIV-infected women than men...
  18. pmc Risk of cervical precancer and cancer among HIV-infected women with normal cervical cytology and no evidence of oncogenic HPV infection
    Marla J Keller
    Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Ave, Mazer Bldg, Room 512, Bronx, NY 10461, USA
    JAMA 308:362-9. 2012
    ..Whether a 3-year or 5-year screening interval could be used in HIV-infected women who are cytologically normal and oncogenic HPV-negative is unknown...
  19. ncbi request reprint Anemia in HIV infection: clinical impact and evidence-based management strategies
    Paul A Volberding
    University of California, San Francisco, CA, USA
    Clin Infect Dis 38:1454-63. 2004
    ....
  20. ncbi request reprint Correlates of CD4+ and CD8+ lymphocyte counts in high-risk immunodeficiency virus (HIV)-seronegative women enrolled in the women's interagency HIV study (WIHS)
    Marek J Nowicki
    Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Hum Immunol 68:342-9. 2007
    ..Multiple demographic and behavioral factors may influence CD4 and CD8 counts in HIV negative women. These factors must be considered in future analyses comparing lymphocyte subsets in HIV positive and negative women...
  21. ncbi request reprint Multidrug resistance (MDR-1) expression in AIDS-related lymphomas
    Anil Tulpule
    Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Leuk Res 26:121-7. 2002
    ..9 months, P=0.003). Strategies to overcome MDR-1 expression may be important for initial treatment in patients with AIDS-NHL...
  22. ncbi request reprint Challenges in the management of Burkitt's lymphoma
    Alexandra M Levine
    Norris Cancer Hospital, University of Southern California, Los Angeles 90033 1048, USA
    Clin Lymphoma 3:S19-25. 2002
    ..With the discovery of highly active antiretroviral therapy, the ability to treat and control Burkitt's lymphoma in patients with HIV has improved...
  23. ncbi request reprint Prognostic factors in HIV-related diffuse large-cell lymphoma: before versus after highly active antiretroviral therapy
    Soon Thye Lim
    Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Clin Oncol 23:8477-82. 2005
    ....
  24. ncbi request reprint Pharmacodynamics and safety of intravenous pegaspargase during remission induction in adults aged 55 years or younger with newly diagnosed acute lymphoblastic leukemia
    Dan Douer
    Division of Hematology, Department of Medicine, Childrens Hospital Los Angeles, University of Southern California Keck Medical School and Norris Comprehensive Cancer Center, Los Angeles 90033, USA
    Blood 109:2744-50. 2007
    ....
  25. ncbi request reprint Treatment of AIDS related non-Hodgkin's lymphoma with combination mitoguazone dihydrochloride and low dose CHOP chemotherapy: results of a phase II study
    Anil Tulpule
    Department of Medicine and Radiology, University of Southern California Medical Center, Norris Cancer Hospital and Research Institute, Los Angeles, CA, USA
    Invest New Drugs 22:63-8. 2004
    ..To evaluate the response and side effects of combination therapy with low dose CHOP chemotherapy and mitoguazone dihydrochloride in patients with non-Hodgkin's lymphoma associated with the acquired immunodeficiency syndrome (AIDS-NHL)...
  26. pmc Hepatitis C virus infection activates the immunologic (type II) isoform of nitric oxide synthase and thereby enhances DNA damage and mutations of cellular genes
    Keigo Machida
    Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 2011 Zonal Ave, Los Angeles, CA 90033, USA
    J Virol 78:8835-43. 2004
    ..NO causes DNA breaks and enhances DNA mutation. This sequence of events provides a mechanism for HCV pathogenesis and oncogenesis...
  27. pmc Hepatitis C virus induces toll-like receptor 4 expression, leading to enhanced production of beta interferon and interleukin-6
    Keigo Machida
    Department of Molecular Microbiology and Immunology, USC Keck School of Medicine, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    J Virol 80:866-74. 2006
    ..In conclusion, HCV infection directly induces TLR4 expression and thereby activates B cells, which may contribute to the host's innate immune responses...
  28. ncbi request reprint Anemia in the setting of cancer and human immunodeficiency virus
    Alexandra M Levine
    Division of Hematology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Clin Infect Dis 37:S304-14. 2003
    ..A potential survival benefit has also been associated with correction of anemia in patients with HIV infection--and possibly in those with cancer as well...
  29. ncbi request reprint Neuropsychological functioning in a cohort of HIV- and hepatitis C virus-infected women
    Jean L Richardson
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    AIDS 19:1659-67. 2005
    ..To evaluate the neurocognitive function in 220 women enrolled in the Women's Interagency HIV Study (WIHS), a study of disease progression in women living with HIV/AIDS and in HIV-negative controls...
  30. pmc Short-term garlic supplementation and highly active antiretroviral treatment adherence, CD4+ cell counts, and human immunodeficiency virus viral load
    Chenglong Liu
    Department of Medicine, Georgetown University Medical Center, Washington, DC, USA
    Altern Ther Health Med 18:18-22. 2012
    ..Researchers rarely have studied garlic's association with antiretroviral therapies, however, even though that association is very relevant clinically...
  31. ncbi request reprint Antiretroviral therapy exposure and incidence of diabetes mellitus in the Women's Interagency HIV Study
    Phyllis C Tien
    San Francisco Veterans Affairs Medical Center, Infectious Disease Section, Department of Medicine, University of California San Francisco, 111W 4150 Clement Street, San Francisco, CA 94121, USA
    AIDS 21:1739-45. 2007
    ..To determine the incidence of diabetes mellitus (DM) in a nationally representative cohort of HIV-infected women and a comparison group of HIV-uninfected women...
  32. ncbi request reprint Recent advances in acquired immunodeficiency syndrome (AIDS)-related lymphoma
    Soon Thye Lim
    University of Southern California, Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    CA Cancer J Clin 55:229-41; 260-1, 264. 2005
    ....
  33. ncbi request reprint Weekly docetaxel is safe and effective in the treatment of advanced-stage acquired immunodeficiency syndrome-related Kaposi sarcoma
    Soon Thye Lim
    Department of Hematology, University of Southern California Keck School of Medicine Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA
    Cancer 103:417-21. 2005
    ..Moreover, no effective therapies have been defined for use after treatment failure with this agent. A Phase II trial was conducted with weekly docetaxel in patients with advanced-stage KS to assess safety and antitumor activity...
  34. pmc Changing patterns of anal canal carcinoma in the United States
    Rebecca A Nelson
    City of Hope, Department of Surgery, Division of Surgical Oncology, 1500 E Duarte Rd, Duarte, CA 91010, USA
    J Clin Oncol 31:1569-75. 2013
    ..Persistent human papillomavirus infection is associated with squamous cell carcinoma of the anal canal (SCCA). With changing sexual behaviors, SCCA incidence and patient demographics may also have changed in recent years...
  35. doi request reprint Malignancies in women with HIV infection
    Amrita Krishnan
    City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010, USA
    Womens Health (Lond Engl) 4:357-68. 2008
    ..The use of therapy has been associated with marked improvement in response rates and overall survival of affected patients...
  36. doi request reprint Prevalence and predictors of metabolic syndrome among HIV-infected and HIV-uninfected women in the Women's Interagency HIV Study
    Magdalena E Sobieszczyk
    Division of Infectious Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 48:272-80. 2008
    ..To assess the prevalence of metabolic syndrome (MetSynd) among participants of the Women's Interagency HIV Study and to describe the association of MetSynd with HIV infection, antiretroviral therapies, and sociodemographic factors...
  37. pmc Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes
    Keigo Machida
    Department of Molecular Microbiology and Immunology, University of Southern California Keck School of Medicine, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 101:4262-7. 2004
    ..These results indicate that HCV induces a mutator phenotype and may transform cells by a hit-and-run mechanism. This finding provides a mechanism of oncogenesis for an RNA virus...
  38. ncbi request reprint Non-AIDS-defining cancers and HIV infection
    Soon Thye Lim
    University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA
    Curr HIV/AIDS Rep 2:146-53. 2005
    ....
  39. ncbi request reprint Making dendritic cells from the inside out: lentiviral vector-mediated gene delivery of granulocyte-macrophage colony-stimulating factor and interleukin 4 into CD14+ monocytes generates dendritic cells in vitro
    Richard C Koya
    Department of Medicine, UCLA Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA
    Hum Gene Ther 15:733-48. 2004
    ..This article demonstrates the proof-of-concept to genetically convert monocytes to DC-type antigen-presenting cells with lentiviral vectors...
  40. pmc Insomnia symptoms and HIV infection among participants in the Women's Interagency HIV Study
    Girardin Jean-Louis
    Sleep Disorders Center, Department of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203 2098, USA
    Sleep 35:131-7. 2012
    ..This study assessed the prevalence of insomnia symptoms among women with and without HIV-infection and examined factors associated with insomnia...
  41. pmc Cervical shedding of HIV-1 RNA among women with low levels of viremia while receiving highly active antiretroviral therapy
    Michael N Neely
    Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Acquir Immune Defic Syndr 44:38-42. 2007
    ..Among women with low or undetectable quantities of HIV-1 RNA in plasma, factors associated with genital HIV-1 RNA shedding, including choice of treatment regimen, are poorly characterized...
  42. ncbi request reprint Characteristics of indolent non-Hodgkin lymphoma in patients with type 1 human immunodeficiency virus infection
    Alexandra M Levine
    Department of Medicine and Pathology, University of Southern California Keck School of Medicine, Los Angeles, California, USA
    Cancer 94:1500-6. 2002
    ..The current study was conducted to describe the clinical, immunologic, and pathologic characteristics of indolent B-cell lymphoma in patients infected with the human immunodeficiency virus (HIV)...
  43. ncbi request reprint Evaluation and management of HIV-infected women
    Alexandra M Levine
    Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Ann Intern Med 136:228-42. 2002
    ..When they are provided the same access to care, HIV-infected women have similar prognoses as HIV-infected men...
  44. ncbi request reprint Neuropsychological functioning in a cohort of HIV infected women: importance of antiretroviral therapy
    Jean L Richardson
    Department of Preventive Medicine, University of Southern California, Los Angeles, USA
    J Int Neuropsychol Soc 8:781-93. 2002
    ..This study emphasizes the critical association of antiretroviral therapy with the risk of neurocognitive impairment in women living with HIV/AIDS...
  45. ncbi request reprint Induction of complete remission using single agent clofarabine in a patient with primary refractory acute myeloblaste leukemia
    Dan Douer
    Division of Hematology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Leuk Lymphoma 44:2135-6. 2003
    ..This is a case report of a patient with primary refractory AML who was treated with clofarabine and achieved a complete response...
  46. ncbi request reprint T-cell lymphoma in HIV-infected patients
    Karo K Arzoo
    Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    J Acquir Immune Defic Syndr 36:1020-7. 2004
    ..T-cell lymphomas differ from B-cell cases in terms of a higher propensity for skin and bone marrow involvement. The median survival of patients with T-cell lymphoma is comparable to that of patients with B-cell AIDS-related lymphoma...
  47. ncbi request reprint The use of lentiviral vectors in gene therapy of leukemia: combinatorial gene delivery of immunomodulators into leukemia cells by state-of-the-art vectors
    Renata Stripecke
    Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Blood Cells Mol Dis 31:28-37. 2003
    ..Therefore, lentiviral vectors offer a simple, versatile, and reliable approach for engineering leukemic cells for use as cell vaccines...
  48. doi request reprint Management of AIDS-related lymphoma
    Alexandra M Levine
    City of Hope National Medical Center, Duarte, CA 91011, USA
    Curr Opin Oncol 20:522-8. 2008
    ..Paradigms of therapy have changed. Although the incidence of AIDS-lymphoma has decreased, the incidence of HIV-associated Hodgkin's lymphoma has increased; mechanisms for these changes in epidemiology will be discussed...
  49. ncbi request reprint The treatment of AIDS-related cancers
    Alexandra M Levine
    USC Norris Cancer Hospital, CA, USA
    Lancet Oncol 4:576-81. 2003
  50. ncbi request reprint Angiogenesis and hematological malignancies
    Soon Thye Lim
    Keck School of Medicine Norris, University of Southern California, Comprehensive Cancer Center, Los Angeles, CA 90033, USA
    Hematology 10:11-24. 2005
    ....
  51. doi request reprint Lymphomas and leukemias due to infectious organisms
    Alexandra M Levine
    City of Hope National Medical Center, Duarte, CA, USA
    Hematology 17:S87-9. 2012
    ..The presentation will focus on the latter three disorders, describing pathogenesis of disease, clinical manifestations and therapeutic options...
  52. ncbi request reprint Use of mammographic screening by HIV-infected women in the Women's Interagency HIV Study (WIHS)
    Susan Preston-Martin
    University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033 0800, USA
    Prev Med 34:386-92. 2002
    ..Although HIV-positive women may be less likely than women in general to receive mammography due to socioeconomic disadvantage, HIV diagnosis may increase opportunities for medical interactions which encourage mammography...
  53. pmc Establishment of B-cell lymphoma cell lines persistently infected with hepatitis C virus in vivo and in vitro: the apoptotic effects of virus infection
    Vicky M H Sung
    Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Virol 77:2134-46. 2003
    ..HCV-infected cell lines show significantly enhanced apoptosis. These B-cell lines provide a reproducible cell culture system for studying the complete replication cycle and biology of HCV infections...
  54. ncbi request reprint A phase I/II trial of pixantrone (BBR2778), methylprednisolone, cisplatin, and cytosine arabinoside (PSHAP) in relapsed/refractory aggressive non-Hodgkin's lymphoma
    Soon Thye Lim
    National Cancer Centre, Singapore
    Leuk Lymphoma 48:374-80. 2007
    ..The recommended dose of pixantrone in combination with methylprednisolone, cytarabine, and cisplatin (PSHAP) is 80 mg/m2. PSHAP is an active salvage regimen and should be further evaluated as a pretransplant cytoreductive regimen...
  55. ncbi request reprint Once-weekly epoetin alfa improves quality of life and increases hemoglobin in anemic HIV+ patients
    Michael S Saag
    AIDS Outpatient Clinic, University of Alabama at Birmingham, Alabama 35294, USA
    AIDS Res Hum Retroviruses 20:1037-45. 2004
    ..Hemoglobin increased significantly in all subgroups of race, zidovudine use, CD4+ cell count, and viral load. Once-weekly epoetin alfa was well tolerated. Once-weekly epoetin alfa is effective in improving QOL and Hb measures...
  56. ncbi request reprint Highly active antiretroviral therapy and cervical squamous intraepithelial lesions in human immunodeficiency virus-positive women
    Linda Ahdieh-Grant
    Johns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Rm E 7014, Baltimore, MD 21205, USA
    J Natl Cancer Inst 96:1070-6. 2004
    ..We assessed the association between use of highly active antiretroviral therapy (HAART) and regression of SIL in HIV-infected women enrolled in the Women's Interagency HIV Study, a large, multicenter, prospective cohort study...
  57. ncbi request reprint Phase I studies of interleukin (IL)-2 and rituximab in B-cell non-hodgkin's lymphoma: IL-2 mediated natural killer cell expansion correlations with clinical response
    William Larry Gluck
    Cancer Center of the Carolinas, Greenville, South Carolina, USA
    Clin Cancer Res 10:2253-64. 2004
    ..Two parallel Phase I studies evaluated combination therapy with rituximab and IL-2 in relapsed or refractory B-cell non-Hodgkin's lymphoma (NHL)...
  58. ncbi request reprint Effects of HIV infection and its treatment on self-reported menstrual abnormalities in women
    L Stewart Massad
    Southern Illinois University School of Medicine, Springfield, Illinois 62794 9640, USA
    J Womens Health (Larchmt) 15:591-8. 2006
    ..To describe menstrual abnormalities among women with HIV...
  59. ncbi request reprint Treatment of HCV-related mantle-cell lymphoma with ribavirin and pegylated interferon Alfa
    Alexandra M Levine
    N Engl J Med 349:2078-9. 2003
  60. ncbi request reprint Human papillomavirus type 16 and immune status in human immunodeficiency virus-seropositive women
    Howard D Strickler
    Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    J Natl Cancer Inst 95:1062-71. 2003
    ..To address this issue, we examined HPV test results from repeated study visits in the WIHS and from an independent study, the HIV Epidemiology Research Study (HERS)...
  61. pmc Serological detection of human papillomavirus type 16 infection in human immunodeficiency virus (HIV)-positive and high-risk HIV-negative women
    Michael J Silverberg
    Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA
    Clin Vaccine Immunol 13:511-9. 2006
    ..Rises among HIV-positive women may more often result from reactivation of a latent HPV infection in the context of HIV-induced immunosuppression, while rises among HIV-negative women may more often result from reinfection with HPV...
  62. pmc Medically eligible women who do not use HAART: the importance of abuse, drug use, and race
    Mardge H Cohen
    CORE Center, Cook County Hospital, Cook County Bureau of Health Services, Chicago, Ill, USA
    Am J Public Health 94:1147-51. 2004
    ..We investigated the prevalence and characteristics of HIV-positive women who do not report highly active antiretroviral therapy (HAART) use...
  63. ncbi request reprint Effect of antiretroviral therapy on the incidence of genital warts and vulvar neoplasia among women with the human immunodeficiency virus
    L Stewart Massad
    Southern Illinois University School of Medicine, Springfield, Illinois 62794 9640, USA
    Am J Obstet Gynecol 190:1241-8. 2004
    ..The purpose of this study was to determine the incidence and predictors of genital warts and vulvar intraepithelial neoplasia among women with the human immunodeficiency virus...
  64. pmc The relationship between cocaine use and human papillomavirus infections in HIV-seropositive and HIV-seronegative women
    Howard Minkoff
    Department of Obstetrics and Gynecology at Maimonides Medical Center and SUNY Downstate, NY 11219, USA
    Infect Dis Obstet Gynecol 2008:587082. 2008
    ..Since both cocaine use and HPV infection are common among HIV-positive women, we sought to determine whether use of cocaine and/or crack influences the natural history of HPV among women with or at high risk of HIV...
  65. pmc Crack cocaine, disease progression, and mortality in a multicenter cohort of HIV-1 positive women
    Judith A Cook
    Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    AIDS 22:1355-63. 2008
    ..This study explores relationships between crack use and HIV-1 disease outcomes in a multicenter cohort of infected women...
  66. ncbi request reprint Incidence of cervical squamous intraepithelial lesions associated with HIV serostatus, CD4 cell counts, and human papillomavirus test results
    Tiffany G Harris
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    JAMA 293:1471-6. 2005
    ....
  67. ncbi request reprint Outcomes after treatment of cervical intraepithelial neoplasia among women with HIV
    L Stewart Massad
    Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794 9640, USA
    J Low Genit Tract Dis 11:90-7. 2007
    ..To describe outcomes after treatment of cervical intraepithelial neoplasia (CIN) in women with HIV...
  68. ncbi request reprint Illicit drug use, depression and their association with highly active antiretroviral therapy in HIV-positive women
    Judith A Cook
    Center on Mental Health Services Research and Policy, Department of Psychiatry M C 912, University of Illinois at Chicago, 1601 W Taylor Street M C 912, Chicago, IL 60612, USA
    Drug Alcohol Depend 89:74-81. 2007
    ..We examined the interaction of illicit drug use and depressive symptoms, and how they affect the subsequent likelihood of highly active antiretroviral therapy (HAART) use among women with HIV/AIDS...
  69. ncbi request reprint HPV testing for triage of HIV-infected women with papanicolaou smears read as atypical squamous cells of uncertain significance
    L Stewart Massad
    Department of Obstetrics and Gynecology, Southern Illinois School of Medicine, Springfield, Illinois 62794, USA
    J Womens Health (Larchmt) 13:147-53. 2004
    ....
  70. ncbi request reprint Association of cutaneous anergy with human papillomavirus and cervical neoplasia in HIV-seropositive and seronegative women
    Tiffany G Harris
    Albert Einstein College of Medicine, Bronx, New York 10461, USA
    AIDS 21:1933-41. 2007
    ..This study assessed the relationship of anergy test results with cervical infection by human papillomavirus (HPV) and cervical neoplasia in HIV-seropositive and seronegative women...
  71. ncbi request reprint Randomized phase I/II study of troxacitabine combined with cytarabine, idarubicin, or topotecan in patients with refractory myeloid leukemias
    Francis J Giles
    Department of Leukemia, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 21:1050-6. 2003
    ..Troxacitabine has significant single-agent activity. This study was conducted to define the dose-limiting toxicities (DLTs) of its combination with cytarabine (ara-C), idarubicin, or topotecan...
  72. pmc Rituximab does not improve clinical outcome in a randomized phase 3 trial of CHOP with or without rituximab in patients with HIV-associated non-Hodgkin lymphoma: AIDS-Malignancies Consortium Trial 010
    Lawrence D Kaplan
    Division of Hematology Oncology, University of California, 400 Parnassus Ave, Rm A 502, San Francisco, CA 94143, USA
    Blood 106:1538-43. 2005
    ..However, these benefits may be offset by an increase in infectious deaths, particularly in those individuals with CD4(+) lymphocyte counts less than 50/mm(3)...
  73. ncbi request reprint Natural history and possible reactivation of human papillomavirus in human immunodeficiency virus-positive women
    Howard D Strickler
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Ave, Belfer 1308, Bronx, NY 10461, USA
    J Natl Cancer Inst 97:577-86. 2005
    ....
  74. ncbi request reprint Combination treatment approaches and novel therapies for lymphoma
    John P Leonard
    Clin Adv Hematol Oncol 5:4-20; quiz 1 p following 20. 2007
  75. ncbi request reprint Primary effusion lymphoma: successful treatment with highly active antiretroviral therapy and rituximab
    Soon Thye Lim
    Ann Hematol 84:551-2. 2005
  76. ncbi request reprint Variants of human papillomaviruses 16 and 18 and their natural history in human immunodeficiency virus-positive women
    Nicolas F Schlecht
    Albert Einstein College of Medicine, Department of Epidemiology and Population Health, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    J Gen Virol 86:2709-20. 2005
    ..If non-European variants are more oncogenic, the effect may involve a late stage in cervical tumorigenesis...
  77. ncbi request reprint Effects of bacterial vaginosis and other genital infections on the natural history of human papillomavirus infection in HIV-1-infected and high-risk HIV-1-uninfected women
    D Heather Watts
    National Institute of Child Health and Human Development, NIH, Bethesda, Maryland 20892 7510, USA
    J Infect Dis 191:1129-39. 2005
    ..Whether the natural history of human papillomavirus (HPV) infection is affected by bacterial vaginosis (BV) or Trichomonas vaginalis (TV) infection has not been adequately investigated in prospective studies...

Research Grants3

  1. AIDS ASSOCIATED MALIGNANCIES CLINICAL TRIALS CONSORTIUM
    Alexandra Levine; Fiscal Year: 2005
    ..The expertise of our labs and experience will be available to the AMC, which will be considered of the highest priority for our Group. ..
  2. WOMEN'S INTERAGENCY HIV STUDY
    Alexandra Levine; Fiscal Year: 2007
    ..abstract_text> ..