Myron J Levin

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Comparison of a live attenuated and an inactivated varicella vaccine to boost the varicella-specific immune response in seropositive people 55 years of age and older
    M J Levine
    Department of Pediatrics Pediatric Infectious Diseases, University of Colorado School of Medicine, Denver 80262, USA
    Vaccine 18:2915-20. 2000
  2. ncbi request reprint Administration of live varicella vaccine to HIV-infected children with current or past significant depression of CD4(+) T cells
    Myron J Levin
    University of Colorado School of Medicine, Denver, Denver, CO 80262, USA
    J Infect Dis 194:247-55. 2006
  3. ncbi request reprint Prevention strategies: herpes zoster, post-herpetic neuralgia and immunogenicity
    Myron J Levin
    Section of Pediatric Infectious Diseases, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80262, USA
    Herpes 14:45-7. 2007
  4. pmc Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine
    M J Levin
    University of Colorado Health Sciences Center, Denver, Colorado, USA
    J Infect Dis 197:825-35. 2008
  5. doi request reprint Varicella vaccination of immunocompromised children
    Myron J Levin
    Department of Pediatrics, Section of Infectious Diseases, University of Colorado School of Medicine, Denver, USA
    J Infect Dis 197:S200-6. 2008
  6. pmc Shedding of live vaccine virus, comparative safety, and influenza-specific antibody responses after administration of live attenuated and inactivated trivalent influenza vaccines to HIV-infected children
    Myron J Levin
    University of Colorado School of Medicine, Aurora, CO 80045 0508, United States
    Vaccine 26:4210-7. 2008
  7. ncbi request reprint Decline in varicella-zoster virus (VZV)-specific cell-mediated immunity with increasing age and boosting with a high-dose VZV vaccine
    Myron J Levin
    Department of Pediatrics, Section of Infectious Diseases, University of Colorado School of Medicine, Denver, Colorado, USA
    J Infect Dis 188:1336-44. 2003
  8. pmc Short-term and long-term effects of highly active antiretroviral therapy on the incidence of herpes zoster in HIV-infected children
    Myron J Levin
    Pediatric Infectious Diseases Section, University of Colorado at Denver Health Sciences Center, Mailstop C227, Building 401, Room R09 108, 1784 Racine Street, Aurora, CO 80045 0508, USA
    J Acquir Immune Defic Syndr 50:182-91. 2009
  9. ncbi request reprint Development of resistance to acyclovir during chronic infection with the Oka vaccine strain of varicella-zoster virus, in an immunosuppressed child
    Myron J Levin
    Section of Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Infect Dis 188:954-9. 2003
  10. ncbi request reprint Herpes zoster with skin lesions and meningitis caused by 2 different genotypes of the Oka varicella-zoster virus vaccine
    Myron J Levin
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80045 0508, USA
    J Infect Dis 198:1444-7. 2008

Detail Information

Publications63

  1. ncbi request reprint Comparison of a live attenuated and an inactivated varicella vaccine to boost the varicella-specific immune response in seropositive people 55 years of age and older
    M J Levine
    Department of Pediatrics Pediatric Infectious Diseases, University of Colorado School of Medicine, Denver 80262, USA
    Vaccine 18:2915-20. 2000
    ..5-21.3 months. There were no differences in immune response to either vaccine in this older age cohort...
  2. ncbi request reprint Administration of live varicella vaccine to HIV-infected children with current or past significant depression of CD4(+) T cells
    Myron J Levin
    University of Colorado School of Medicine, Denver, Denver, CO 80262, USA
    J Infect Dis 194:247-55. 2006
    ..The licensed, live attenuated varicella vaccine is safe and immunogenic in HIV-infected children with minimal symptoms and good preservation of CD4(+) T cells (Centers for Disease Control and Prevention immunologic category 1)...
  3. ncbi request reprint Prevention strategies: herpes zoster, post-herpetic neuralgia and immunogenicity
    Myron J Levin
    Section of Pediatric Infectious Diseases, Department of Pediatrics, University of Colorado School of Medicine, Denver, CO 80262, USA
    Herpes 14:45-7. 2007
    ..It is likely that the vaccine-induced boost in VZV-specific CMI reversed the natural decline in these responses that occurs as part of the ageing process, thereby protecting vaccine recipients against herpes zoster and its complications...
  4. pmc Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine
    M J Levin
    University of Colorado Health Sciences Center, Denver, Colorado, USA
    J Infect Dis 197:825-35. 2008
    ..The trial included an immunology substudy to determine the relationship of VZV-specific immune responses to vaccination and clinical outcome...
  5. doi request reprint Varicella vaccination of immunocompromised children
    Myron J Levin
    Department of Pediatrics, Section of Infectious Diseases, University of Colorado School of Medicine, Denver, USA
    J Infect Dis 197:S200-6. 2008
    ..Numerous trials have been undertaken to vaccinate children who are immunocompromised by a variety of conditions and therapies that depress their immune function...
  6. pmc Shedding of live vaccine virus, comparative safety, and influenza-specific antibody responses after administration of live attenuated and inactivated trivalent influenza vaccines to HIV-infected children
    Myron J Levin
    University of Colorado School of Medicine, Aurora, CO 80045 0508, United States
    Vaccine 26:4210-7. 2008
    ..LAIV should be further evaluated for a role in immunizing HIV-infected children...
  7. ncbi request reprint Decline in varicella-zoster virus (VZV)-specific cell-mediated immunity with increasing age and boosting with a high-dose VZV vaccine
    Myron J Levin
    Department of Pediatrics, Section of Infectious Diseases, University of Colorado School of Medicine, Denver, Colorado, USA
    J Infect Dis 188:1336-44. 2003
    ..A live attenuated VZV vaccine is safe and immunogenic in an elderly population, and the vaccine-induced immunity may be monitored by the IFN-gamma ELISPOT assay...
  8. pmc Short-term and long-term effects of highly active antiretroviral therapy on the incidence of herpes zoster in HIV-infected children
    Myron J Levin
    Pediatric Infectious Diseases Section, University of Colorado at Denver Health Sciences Center, Mailstop C227, Building 401, Room R09 108, 1784 Racine Street, Aurora, CO 80045 0508, USA
    J Acquir Immune Defic Syndr 50:182-91. 2009
    ..Highly active antiretroviral therapy (HAART) has reduced herpes zoster (HZ) incidence in HIV-infected children, yet it remains common...
  9. ncbi request reprint Development of resistance to acyclovir during chronic infection with the Oka vaccine strain of varicella-zoster virus, in an immunosuppressed child
    Myron J Levin
    Section of Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Infect Dis 188:954-9. 2003
    ..This is the first report of Oka-strain varicella virus causing severe disease after reactivation and of resistance to acyclovir during an infection caused by this virus...
  10. ncbi request reprint Herpes zoster with skin lesions and meningitis caused by 2 different genotypes of the Oka varicella-zoster virus vaccine
    Myron J Levin
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80045 0508, USA
    J Infect Dis 198:1444-7. 2008
    ..The presence of distinct strains in skin lesions and cerebrospinal fluid indicate that >1 variant strain may reactivate to cause herpes zoster...
  11. pmc Varicella-zoster virus DNA in cells isolated from human trigeminal ganglia
    Myron J Levin
    Section of Pediatric Infectious Diseases, School of Medicine, University of Colorado, Denver, Colorado 80262, USA
    J Virol 77:6979-87. 2003
    ..There was an average of 4.7 (range of 2 to 9) copies of VZV DNA per latently infected neuron. Latent VZV DNA was primarily present in large neurons, whereas the size distribution of herpes simplex virus DNA was markedly different...
  12. pmc Influence of age and nature of primary infection on varicella-zoster virus-specific cell-mediated immune responses
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, Colorado, USA
    J Infect Dis 201:1024-30. 2010
    ..We studied the relationship between VZV cell-mediated immunity and age after varicella or VZV vaccination in healthy and human immunodeficiency virus (HIV)-infected individuals...
  13. ncbi request reprint Pertussis booster vaccination in HIV-infected children receiving highly active antiretroviral therapy
    Mark J Abzug
    School of Medicine, University of Colorado and Children s Hospital, Denver, Colorado, USA
    Pediatrics 120:e1190-202. 2007
    ..Our goal was to evaluate the immunogenicity and safety of pertussis booster vaccination in children infected with HIV on highly active antiretroviral therapy (HAART)...
  14. pmc Kinetics and determining factors of the virologic response to antiretrovirals during pregnancy
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    Infect Dis Obstet Gynecol 2009:621780. 2009
    ..In conclusion, the virologic responses of pregnant and nonpregnant adults share similar characteristics...
  15. pmc A phase I-II study of live attenuated varicella-zoster virus vaccine to boost immunity in human immunodeficiency virus-infected children with previous varicella
    Anne A Gershon
    Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Pediatr Infect Dis J 28:653-5. 2009
    ..There were no serious adverse events. Two years after vaccination 82% of subjects remained VZV-antibody positive and 60% had VZV-specific cell-mediated immunity. No child developed herpes zoster...
  16. pmc Immunogenicity and immunologic memory after hepatitis B virus booster vaccination in HIV-infected children receiving highly active antiretroviral therapy
    Mark J Abzug
    University of Colorado Denver School of Medicine and The Children s Hospital, 13123 E 16th Avenue, Aurora, CO 80045, USA
    J Infect Dis 200:935-46. 2009
    ..The immunogenicity of HBV vaccination in children receiving highly active antiretroviral therapy (HAART) was investigated...
  17. ncbi request reprint Cytomegalovirus-specific cell-mediated immunity in HIV-infected children on HAART
    Adriana Weinberg
    Section of Pediatric Infectious Diseases, University of Colorado School of Medicine, Denver, Colorado 80262, USA
    AIDS Res Hum Retroviruses 22:283-8. 2006
    ....
  18. pmc T cell responses of HIV-infected children after administration of inactivated or live attenuated influenza vaccines
    Adriana Weinberg
    University of Colorado Denver, Aurora, 80045, USA
    AIDS Res Hum Retroviruses 26:51-9. 2010
    ..LAIV administration suppressed ELISPOT responses less. The clinical significance of these findings deserves further study...
  19. ncbi request reprint Factors that affect in vitro measurement of the susceptibility of herpes simplex virus to nucleoside analogues
    Adriana Weinberg
    Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Denver, CO, United States
    J Clin Virol 38:139-45. 2007
    ..To identify factors that contribute to variability of HSV antiviral susceptibility breakpoints...
  20. pmc Safety and tolerability of antiretrovirals during pregnancy
    Adriana Weinberg
    School of Medicine University of Colorado Denver, Research Complex, Aurora, CO 80045, USA
    Infect Dis Obstet Gynecol 2011:867674. 2011
    ..Our data emphasize the need to revise the treatment recommendations for pregnant women to include safer and better-tolerated drugs...
  21. pmc Safety and immunogenicity of a quadrivalent human papillomavirus (types 6, 11, 16, and 18) vaccine in HIV-infected children 7 to 12 years old
    Myron J Levin
    Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO, USA
    J Acquir Immune Defic Syndr 55:197-204. 2010
    ..Quadrivalent human papillomavirus vaccine (QHPV) is > 95% effective in preventing infection with vaccine-type human papillomavirus. The safety and immunogenicity of QHPV are unknown in HIV-infected children...
  22. ncbi request reprint Kinetics of viral shedding and immune responses in adults following administration of cold-adapted influenza vaccine
    Laura L Hammitt
    Section of Infectious Diseases, Department of Pediatrics, University of Colorado Denver, Denver, CO, United States
    Vaccine 27:7359-66. 2009
    ..PBMCs from subjects receiving CAIV showed a higher proportion of functional, tissue-tropic T-cells (CD4+CD69+CD18+MIP1alpha+) specific for homotypic and heterosubtypic strains of influenza by flow cytometry...
  23. pmc Safety and immunogenicity of 2009 pH1N1 vaccination in HIV-infected pregnant women
    Mark J Abzug
    Department of Pediatrics, Infectious Diseases, University of Colorado School of Medicine and Children s Hospital Colorado, Aurora, CO, USA
    Clin Infect Dis 56:1488-97. 2013
    ..The safety and immunogenicity of pH1N1 vaccination in HIV-infected pregnant women are unknown...
  24. pmc Immunogenicity, immunologic memory, and safety following measles revaccination in HIV-infected children receiving highly active antiretroviral therapy
    Mark J Abzug
    Pediatric Infectious Diseases, Box B055, Children s Hospital Colorado, 13123 East 16th Ave, Aurora, CO 80045, USA
    J Infect Dis 206:512-22. 2012
    ..Response rates and immunologic memory following measles vaccination are reduced in human immunodeficiency virus (HIV)-infected children in the absence of highly active antiretroviral therapy (HAART)...
  25. pmc Virologic and immunologic correlates with the magnitude of antibody responses to the hepatitis A vaccine in HIV-infected children on highly active antiretroviral treatment
    Adriana Weinberg
    Department of Pediatrics, University of Colorado Denver, Aurora, CO 80045, USA
    J Acquir Immune Defic Syndr 52:17-24. 2009
    ..We sought to identify the immunologic and virologic factors associated with a robust response to hepatitis A virus (HAV) vaccine in children on highly active antiretroviral treatment...
  26. ncbi request reprint Safety and immunogenicity of a live attenuated varicella vaccine in VZV-seropositive HIV-infected adults
    Adriana Weinberg
    University of Colorado Denver School of Medicine, Aurora, CO, USA
    Hum Vaccin 6:318-21. 2010
    ..We evaluated the safety and immunogenicity of a live attenuated varicella-zoster virus (VZV) vaccine as a candidate for protecting HIV-infected adults against herpes-zoster...
  27. pmc Varicella-zoster virus-specific immune responses to herpes zoster in elderly participants in a trial of a clinically effective zoster vaccine
    Adriana Weinberg
    University of Colorado Denver, Denver, CO, USA
    J Infect Dis 200:1068-77. 2009
    ....
  28. ncbi request reprint Varicella-Zoster virus-specific cell-mediated immunity in HIV-infected children receiving highly active antiretroviral therapy
    Adriana Weinberg
    Section of Pediatric Infectious Diseases, and Department of Medicine, University of Colorado School of Medicine, Denver, Colorado, USA
    J Infect Dis 190:267-70. 2004
    ..After developing HZ, only the 2 HAART-compliant patients developed VZV-CMI. Thus, VZV-specific immune reconstitution in HIV infection may require antigenic reexposure, in addition to control of HIV replication...
  29. ncbi request reprint Resistance of herpes simplex virus infections to nucleoside analogues in HIV-infected patients
    Myron J Levin
    Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Denver, USA
    Clin Infect Dis 39:S248-57. 2004
    ..This article reviews the prevalence, pathogenesis, and implications of drug-resistant HSV infections in HIV-infected patients...
  30. ncbi request reprint Prevention strategies for herpes zoster and post-herpetic neuralgia
    Myron J Levin
    Pediatric Infectious Diseases, University of Colorado Denver, Mail Stop C227, Building 401, 1784 Racine Street, Room R09 108, Aurora, CO 80045, USA
    J Clin Virol 48:S14-9. 2010
    ..Other strategies focus on preventing the major complication of HZ--post-herpetic neuralgia. These strategies include pre-emptive treatment with drugs such as tricyclic antidepressants, anticonvulsants and analgesics...
  31. pmc Postentry events are responsible for restriction of productive varicella-zoster virus infection in Chinese hamster ovary cells
    Renée L Finnen
    Department of Pediatrics, Infectious Diseases Section, Biomedical Research Building 851, C227, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    J Virol 80:10325-34. 2006
    ..Infection of CHO-K1 cells by VZV resulted in the production of both immediate early and late gene products, indicating that a block to progeny virus production occurs after the initiation of virus gene expression...
  32. pmc Humoral, mucosal, and cell-mediated immunity against vaccine and nonvaccine genotypes after administration of quadrivalent human papillomavirus vaccine to HIV-infected children
    Adriana Weinberg
    University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Infect Dis 206:1309-18. 2012
    ..To characterize the immunogenicity of a quadrivalent human papillomavirus vaccine (QHPV) in human immunodeficiency virus (HIV)-infected children, we studied their immune responses to 3 or 4 doses...
  33. pmc Immune correlates of herpes zoster in HIV-infected children and youth
    Adriana Weinberg
    University of Colorado Denver, Aurora, Colorado, USA
    J Virol 86:2878-81. 2012
    ..In contrast, high nonspecific regulatory and activated T cells were associated with an increased risk of HZ...
  34. doi request reprint VZV T cell-mediated immunity
    Adriana Weinberg
    University of Colorado Denver, Aurora, CO 80045, USA
    Curr Top Microbiol Immunol 342:341-57. 2010
    ..Similarly, the magnitude of these responses early after the onset of herpes zoster correlates with the extent of zoster-associated pain. These essential immune responses are boosted by the VZV vaccine developed to prevent herpes zoster...
  35. ncbi request reprint Immunogenicity, safety, and predictors of response after a pneumococcal conjugate and pneumococcal polysaccharide vaccine series in human immunodeficiency virus-infected children receiving highly active antiretroviral therapy
    Mark J Abzug
    University of Colorado School of Medicine, Pediatric Infectious Disease, The Children s Hospital, Denver, CO 80218, USA
    Pediatr Infect Dis J 25:920-9. 2006
    ....
  36. doi request reprint Varicella vaccine in the United States: a decade of prevention and the way forward
    Anne A Gershon
    Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York, USA
    J Infect Dis 197:S39-40. 2008
  37. ncbi request reprint Advances in the understanding of the pathogenesis and epidemiology of herpes zoster
    Anne A Gershon
    Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Clin Virol 48:S2-7. 2010
    ..Understanding the risk factors for developing HZ and the complications associated with infection, particularly in older people, is important for prompt diagnosis and management of HZ in primary care, and they are therefore also reviewed...
  38. ncbi request reprint Phenotypic and functional characterization of ex vivo T cell responses to the live attenuated herpes zoster vaccine
    Julie Patterson-Bartlett
    Department of Pediatrics of the University of Colorado School of Medicine, Denver, CO 80262, USA
    Vaccine 25:7087-93. 2007
    ..The vaccine significantly increased VZV-specific Th1, memory, early effector, and cutaneous homing receptor-bearing T cells...
  39. ncbi request reprint Fractionation of neurons and satellite cells from human sensory ganglia in order to study herpesvirus latency
    Guang Yun Cai
    Department of Pediatrics, Section of Pediatric Infectious Diseases, School of Medicine, University of Colorado, Box C 227, 4200 East Ninth Avenue, Denver, CO 80262, USA
    J Virol Methods 104:21-32. 2002
    ....
  40. doi request reprint Early treatment of cold sores with topical ME-609 decreases the frequency of ulcerative lesions: a randomized, double-blind, placebo-controlled, patient-initiated clinical trial
    Christopher M Hull
    Department of Dermatology, School of Medicine, University of Utah, Salt Lake City, Utah 84132 2409, USA
    J Am Acad Dermatol 64:696.e1-11. 2011
    ..ME-609 (Xerese, Xerclear) is a combination of 5% acyclovir and 1% hydrocortisone developed for the topical treatment of HSL...
  41. ncbi request reprint Susceptibility of herpes simplex virus isolates to nucleoside analogues and the proportion of nucleoside-resistant variants after repeated topical application of penciclovir to recurrent herpes labialis
    Young Kyoo Shin
    Section of Pediatric Infectious Diseases, School of Medicine, University of Colorado, Denver, Colorado, USA
    J Infect Dis 187:1241-5. 2003
    ..We conclude that antiviral-resistant variants, which are readily detected in HSV isolates from peripheral lesions, do not accumulate in the sensory ganglia of immunocompetent patients receiving multiple courses of nucleoside analogues...
  42. doi request reprint Resistance to antiretrovirals in HIV-infected pregnant women
    Adriana Weinberg
    University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Clin Virol 45:39-42. 2009
    ..Antiretrovirals suppress HIV replication and prevent mother-to-child-transmission of HIV (PMTCT). Resistance to antiretrovirals may reduce the efficacy of PMTCT and/or complicate treatment of maternal or infant infection...
  43. pmc Human sensory neurons derived from induced pluripotent stem cells support varicella-zoster virus infection
    Katherine S Lee
    Department of Pediatrics, Section of Infectious Diseases, University of Colorado Denver, Aurora, Colorado, United States of America
    PLoS ONE 7:e53010. 2012
    ..Since limited neuronal populations are capable of supporting the entire VZV and HSV life cycles, our iPS-derived sensory neuron model may prove useful for studying alphaherpesvirus latency and reactivation...
  44. ncbi request reprint Clinical and in vitro evaluation of cidofovir for treatment of adenovirus infection in pediatric hematopoietic stem cell transplant recipients
    William J Muller
    Department of Pediatrics, Division of Infectious Diseases, University of Washington, Seattle, USA
    Clin Infect Dis 41:1812-6. 2005
    ..In vitro susceptibility to cidofovir was demonstrated in 12 clinical adenovirus isolates. Cidofovir is a promising treatment option for this population...
  45. doi request reprint Workshop on immunizations in older adults: identifying future research agendas
    Kevin P High
    Division of Infectious Diseases, Department of Internal Medicine, School of Medicine, Wake Forest University, Winston Salem, North Carolina 27157, USA
    J Am Geriatr Soc 58:765-76. 2010
    ....
  46. ncbi request reprint Responder cell frequency estimation and binomial three-level nonlinear mixed effects model in limiting dilution assays
    Misoo C Ellison
    Division of Biostatistics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    J Biopharm Stat 15:165-78. 2005
    ..In this article, an algorithm for the three-level nonlinear mixed-effects model, which can be inserted into the code in the SAS procedure NLMIXED, is suggested...
  47. ncbi request reprint Nectin-1/HveC Mediates herpes simplex virus type 1 entry into primary human sensory neurons and fibroblasts
    Scott A Simpson
    Department of Pediatrics, Section of Infectious Diseases, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Neurovirol 11:208-18. 2005
    ..However, in contrast to the results obtained with neurons, antibodies against receptors failed to inhibit entry into fibroblasts, indicating that unlike neurons, fibroblasts have multiple receptors or mechanisms for HSV-1 entry...
  48. ncbi request reprint Immune senescence and vaccines to prevent herpes zoster in older persons
    Myron J Levin
    Section of Pediatric Infectious Diseases, University of Colorado Denver School of Medicine and Health Sciences Center, C227, Building 401, 1784 Racine Street, Aurora, CO 80045, USA
    Curr Opin Immunol 24:494-500. 2012
    ..Based on information from these studies some potential approaches to improving prevention of herpes zoster are discussed...
  49. ncbi request reprint Phase I/II trial of intravenous recombinant interleukin-2 in HIV-infected children
    Stuart E Starr
    Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, USA
    AIDS 17:2181-9. 2003
    ..To define the tolerated dose of recombinant interleukin-2 (rIL-2) in HIV-infected children (part A), and to determine the safety and immunologic effects of the tolerated rIL-2 dose in a cohort of HIV-infected children (part B)...
  50. pmc Susceptibilities of herpes simplex viruses to penciclovir and acyclovir in eight cell lines
    Jeffry J Leary
    GlaxoSmithKline, The Antimicrobial and Host Defense Center of Excellence for Drug Discovery, Department of Host Defense, Collegeville, Pennsylvania, USA
    Antimicrob Agents Chemother 46:762-8. 2002
    ..Comparison experiments with a yield reduction format indicated that the use of assays of this type might allow some of the cell-specific properties observed in plaque reduction assays to be avoided...
  51. pmc Herpes simplex virus resistance to acyclovir and penciclovir after two decades of antiviral therapy
    Teresa H Bacon
    GlaxoSmithKline Consumer Healthcare, Weybridge, Surrey KT15 0DE, United Kingdom
    Clin Microbiol Rev 16:114-28. 2003
    ..These observations are examined in the light of characteristics of the virus, the drugs, and host factors...
  52. pmc Varicella-zoster virus activates inflammatory cytokines in human monocytes and macrophages via Toll-like receptor 2
    Jennifer P Wang
    Department of Medicine, University of Massachusetts Medical Center, Worcester, 01605, USA
    J Virol 79:12658-66. 2005
    ..Together, these results suggest that TLR2 may play a role in the inflammatory response to VZV infection...
  53. ncbi request reprint Recommendations for the management of herpes zoster
    Robert H Dworkin
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
    Clin Infect Dis 44:S1-26. 2007
    ..Specific recommendations for the use of these medications are provided. In addition, suggestions are made for treatments that, when used in combination with antiviral therapy, may further reduce pain and other complications of HZ...
  54. ncbi request reprint DNA sequence variability in isolates recovered from patients with postvaccination rash or herpes zoster caused by Oka varicella vaccine
    Vladimir N Loparev
    National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Infect Dis 195:502-10. 2007
    ..5%-97.4% of isolates (mean frequency, 67.7%). No 2 clinical isolates had identical SNP profiles; as such, vaccine latency usually involves >1 strain...
  55. pmc Vaccination against Herpes Zoster and Postherpetic Neuralgia
    Michael N Oxman
    VA San Diego Healthcare System, San Diego, California, USA
    J Infect Dis 197:S228-36. 2008
    ..VZV vaccines can boost VZV-CMI. Therefore, we tested the hypothesis that VZV vaccination would protect older adults against HZ and PHN...
  56. ncbi request reprint Cost-effectiveness of herpes zoster vaccine: flawed assumptions regarding efficacy against postherpetic neuralgia
    Marc Brisson
    Clin Infect Dis 45:1527-9. 2007
  57. ncbi request reprint Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP)
    Rafael Harpaz
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, USA
    MMWR Recomm Rep 57:1-30; quiz CE2-4. 2008
    ..Before administration of zoster vaccine, patients do not need to be asked about their history of varicella (chickenpox) or to have serologic testing conducted to determine varicella immunity...
  58. ncbi request reprint Development of a measure of the burden of pain due to herpes zoster and postherpetic neuralgia for prevention trials: adaptation of the brief pain inventory
    Paul M Coplan
    Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    J Pain 5:344-56. 2004
    ..These findings support the validity and utility of the ZBPI, the definition of PHN, and the severity-duration measure of the burden of HZ illness...
  59. ncbi request reprint Hepatitis C prevalence in children with perinatal human immunodeficiency virus infection enrolled in a long-term follow-up protocol
    Susan Schuval
    Schneider Children s Hospital, Long Island Jewish Medical Center, New Hyde Park, NY 11042, USA
    Arch Pediatr Adolesc Med 158:1007-13. 2004
    ..To evaluate the prevalence of hepatitis C virus (HCV) infection in children with perinatal human immunodeficiency virus (HIV) infection...
  60. ncbi request reprint GB virus C infection in children with perinatal human immunodeficiency virus infection
    Susan Schuval
    Schneider Children s Hospital, Long Island Jewish Medical Center, New Hyde Park, NY 11042, USA
    Pediatr Infect Dis J 24:417-22. 2005
    ..GB virus C (GBV-C) infection occurs in 20-40% of human immunodeficiency virus (HIV)-infected adults, and coinfection is associated with improved HIV disease outcome...
  61. ncbi request reprint The impact of acute herpes zoster pain and discomfort on functional status and quality of life in older adults
    Kenneth E Schmader
    Duke University, Durham, NC, USA
    Clin J Pain 23:490-6. 2007
    ....
  62. ncbi request reprint Evaluation of the cost-effectiveness in the United States of a vaccine to prevent herpes zoster and postherpetic neuralgia in older adults
    James M Pellissier
    Merck Research Laboratories, Blue Bell, PA, United States
    Vaccine 25:8326-37. 2007
    ..s.)...
  63. ncbi request reprint The prevention and management of herpes zoster
    Anthony L Cunningham
    University of Sydney, Sydney, NSW, Australia
    Med J Aust 188:171-6. 2008
    ..Clinicians should refer to the Australian immunisation handbook for advice on the use of the live vaccine in immunosuppressed individuals...