Milton Levin

Summary

Affiliation: University of Connecticut
Country: USA

Publications

  1. ncbi Specific non-coplanar PCB-mediated modulation of bottlenose dolphin and beluga whale phagocytosis upon in vitro exposure
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 67:1517-35. 2004
  2. ncbi Immunomodulatory effects of domoic acid differ between in vivo and in vitro exposure in mice
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA
    Mar Drugs 6:636-59. 2008
  3. ncbi Immunomodulatory effects of organochlorine mixtures upon in vitro exposure of peripheral blood leukocytes differ between free-ranging and captive southern sea otters (Enhydra lutris)
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, U 89 Storrs, CT 06269, USA
    Vet Immunol Immunopathol 119:269-77. 2007
  4. ncbi Non-coplanar PCBs induce calcium mobilization in bottlenose dolphin and beluga whale, but not in mouse leukocytes
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 70:1220-31. 2007
  5. ncbi Modulation of the respiratory burst by organochlorine mixtures in marine mammals, humans, and mice
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 70:73-83. 2007
  6. ncbi Non-coplanar PCB-mediated modulation of human leukocyte phagocytosis: a new mechanism for immunotoxicity
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 68:1977-93. 2005
  7. ncbi Association between lymphocyte proliferation and polychlorinated biphenyls in free-ranging harbor seal (Phoca vitulina) pups from British Columbia, Canada
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, U 89, Storrs, Connecticut 06269, USA
    Environ Toxicol Chem 24:1247-52. 2005
  8. ncbi PCBs and TCDD, alone and in mixtures, modulate marine mammal but not B6C3F1 mouse leukocyte phagocytosis
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 68:635-56. 2005
  9. ncbi Immunomodulatory effects upon in vitro exposure of California sea lion and southern sea otter peripheral blood leukocytes to domoic acid
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North, Eagleville Road, U 3089, Storrs, Connecticut 06269, USA
    J Wildl Dis 46:541-50. 2010
  10. ncbi Effects of organochlorines, individually and in mixtures, on B-cell proliferation in marine mammals and mice
    Chiharu Mori
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 71:266-75. 2008

Detail Information

Publications11

  1. ncbi Specific non-coplanar PCB-mediated modulation of bottlenose dolphin and beluga whale phagocytosis upon in vitro exposure
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 67:1517-35. 2004
    ..This is the first report demonstrating the immunomodulatory effects of OCs on dolphin and beluga phagocytosis, and the first overall demonstration of immunomodulatory effects on phagocytosis mediated specifically by non-coplanar PCBs...
  2. ncbi Immunomodulatory effects of domoic acid differ between in vivo and in vitro exposure in mice
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT 06269, USA
    Mar Drugs 6:636-59. 2008
    ..Modulation of cytosolic calcium suggests that DA exerts its effects through ionotropic glutamate subtype surface receptors at least on monocytes. This study is the first to identify DA as an immunotoxic chemical in a mammalian species...
  3. ncbi Immunomodulatory effects of organochlorine mixtures upon in vitro exposure of peripheral blood leukocytes differ between free-ranging and captive southern sea otters (Enhydra lutris)
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, U 89 Storrs, CT 06269, USA
    Vet Immunol Immunopathol 119:269-77. 2007
    ..Understanding differences in toxicity to different populations of sea otters will have important implications for risk assessment as well as conservation and management strategies...
  4. ncbi Non-coplanar PCBs induce calcium mobilization in bottlenose dolphin and beluga whale, but not in mouse leukocytes
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 70:1220-31. 2007
    ..These results demonstrate for the first time the direct effects of non-coplanar PCBs on Ca2+ mobilization in marine mammals, which may be involved in the modulation of phagocytosis previously observed in these species...
  5. ncbi Modulation of the respiratory burst by organochlorine mixtures in marine mammals, humans, and mice
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 70:73-83. 2007
    ..Elucidating the relative sensitivities to the immunomodulatory effects of OC mixtures between different species may have important implications for risk assessment as well as conservation and management strategies...
  6. ncbi Non-coplanar PCB-mediated modulation of human leukocyte phagocytosis: a new mechanism for immunotoxicity
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 68:1977-93. 2005
    ..Our results are cause for concern as they suggest an AhR-independent pathway through which non-coplanar PCBs modulate phagocytosis, the immune system's first line of defense, possibly increasing the risk to developing infectious disease...
  7. ncbi Association between lymphocyte proliferation and polychlorinated biphenyls in free-ranging harbor seal (Phoca vitulina) pups from British Columbia, Canada
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North Eagleville Road, U 89, Storrs, Connecticut 06269, USA
    Environ Toxicol Chem 24:1247-52. 2005
    ..Further research is needed to evaluate the relative roles of natural and contaminant-related influences on the immune system of marine mammals...
  8. ncbi PCBs and TCDD, alone and in mixtures, modulate marine mammal but not B6C3F1 mouse leukocyte phagocytosis
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 68:635-56. 2005
    ....
  9. ncbi Immunomodulatory effects upon in vitro exposure of California sea lion and southern sea otter peripheral blood leukocytes to domoic acid
    Milton Levin
    Department of Pathobiology and Veterinary Science, University of Connecticut, 61 North, Eagleville Road, U 3089, Storrs, Connecticut 06269, USA
    J Wildl Dis 46:541-50. 2010
    ....
  10. ncbi Effects of organochlorines, individually and in mixtures, on B-cell proliferation in marine mammals and mice
    Chiharu Mori
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 71:266-75. 2008
    ..These findings may be helpful in more accurately characterizing the immunotoxic potential of OC in different target species and help in more relevant risk assessment...
  11. ncbi Immunomodulatory effects of in vitro exposure to organochlorines on T-cell proliferation in marine mammals and mice
    Chiharu Mori
    Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut 06269, USA
    J Toxicol Environ Health A 69:283-302. 2006
    ..These findings will be useful to better characterize the risk associated with OC exposure and possibly lead to new conservation and management strategies...