Research Topics
Species | JACQUELINE LEUNGSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Does using a femoral nerve block for total knee replacement decrease postoperative delirium?Sakura Kinjo
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143 0648, USA
BMC Anesthesiol 12:4. 2012..abstract:..- Brief report: preoperative frailty in older surgical patients is associated with early postoperative deliriumJacqueline M Leung
MPH, Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, CA 94143 0648, USA
Anesth Analg 112:1199-201. 2011..42; 95% confidence interval=1.06-1.91; P=0.018) and the frailty score (odds ratio=1.84; 95% confidence interval=1.07-3.1; P=0.028) were independently associated with the development of postoperative delirium... - Does postoperative delirium limit the use of patient-controlled analgesia in older surgical patients?Jacqueline M Leung
Department of Anesthesia and Perioperative Care, University of California, San Francisco, 521 Parnassus, Room C 450, San Francisco, California 94143 0648, USA
Anesthesiology 111:625-31. 2009..BACKGROUNDPostoperative pain Is an independent predictor of postoperative delirium. Whether postoperative delirium limits patient-controlled analgesia (PCA) use has not been determined... 
Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgeryJacqueline M Leung
Anesthesia and Perioperative Care, University of California, San Francisco, California 94143 0648, USA
Anesthesiology 107:406-11. 2007..Whether patients who subsequently develop early postoperative delirium have a genetic predisposition that renders them at risk for postoperative delirium has not been determined...- Pilot clinical trial of gabapentin to decrease postoperative delirium in older patientsJ M Leung
Department of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, CA 94143 0648, USA
Neurology 67:1251-3. 2006..Postoperative delirium occurred in 5/12 patients (42%) who received placebo vs 0/9 patients who received gabapentin, p = 0.045. The reduction in delirium appears to be secondary to the opioid-sparing effect of gabapentin... - Nitrous oxide does not change the incidence of postoperative delirium or cognitive decline in elderly surgical patientsJ M Leung
Department of Anesthesia and Perioperative Care, University of California, 521 Parnassus, San Francisco, 94143 0648, USA
Br J Anaesth 96:754-60. 2006..We hypothesized that in the elderly patients undergoing non-cardiac surgery, exposure to N(2)O resulted in an increased incidence of postoperative delirium than would be expected for patients not receiving N(2)O... - Increases in P-wave dispersion predict postoperative atrial fibrillation after coronary artery bypass graft surgeryJoby Chandy
Department of Anesthesia and Perioperative Care, University of California, San Francisco, USA
Anesth Analg 98:303-10, table of contents. 2004.... - Postoperative delirium: the importance of pain and pain managementLinnea E Vaurio
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143-0648, USA
Anesth Analg 102:1267-73. 2006..4; 95% CI 0.2 to 0.7). These results validate our hypothesis that pain and pain management strategies are important factors related to the development of postoperative delirium in elderly patients... - The relative importance of left atrial function versus dimension in predicting atrial fibrillation after coronary artery bypass graft surgeryToshiko Nakai
Department of Medicine, Section of Cardiac Electrophysiology, and Cardiovascular Research Institute, University of California, San Francisco 94143, USA
Am Heart J 143:181-6. 2002..The purpose of this study was to determine whether pre-existing left atrial dysfunction is a predictor of postoperative AF compared with other clinical predictors... - Are preoperative depressive symptoms associated with postoperative delirium in geriatric surgical patients?Jacqueline M Leung
Department of Anesthesia and Perioperative Care, University of California, San Francisco, CA 94143 0648, USA
J Gerontol A Biol Sci Med Sci 60:1563-8. 2005..Our study aimed to examine the prevalence and prognostic importance of preoperative depressive symptoms in older surgical patients... - Impairment of left atrial function predicts post-operative atrial fibrillation after coronary artery bypass graft surgeryJacqueline M Leung
Department of Anesthesia and Perioperative Care, University of California, 521 Parnassus Avenue, San Francisco, CA 94143 0648, USA
Eur Heart J 25:1836-44. 2004..This study sought to determine the relationship between LA function and post-operative AF... - Does intraoperative evaluation of left ventricular contractile reserve predict myocardial viability? A clinical study using dobutamine stress echocardiography in patients undergoing coronary artery bypass graft surgeryJacqueline M Leung
Department of Anesthesia and Perioperative Care, University of California San Francisco, 521 Parnassus Ave, San Francisco, CA 94143 0648, USA
Anesth Analg 99:647-54, table of contents. 2004..The majority of new postbypass regional wall motion abnormalities appear to be related to stunned myocardium... - Preoperative electrocardiogram abnormalities do not predict postoperative cardiac complications in geriatric surgical patientsLinda L Liu
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143, USA
J Am Geriatr Soc 50:1186-91. 2002..This study was designed to determine whether abnormalities on preoperative ECGs were predictive of postoperative cardiac complications... - Comparison of left atrial dimensions by transesophageal and transthoracic echocardiographyMatthew Block
Department of Medicine, California Pacific Medical Center, San Francisco, CA, USA
J Am Soc Echocardiogr 15:143-9. 2002..86; bias 0.37 +/- 1 cm). Overall, TEE underestimated the LA dimension by 9% compared with TTE. These results suggest that the short-axis view at the level of the aortic valve is the preferred site for measuring the LA dimension by TEE... - The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic reviewHarold K Fong
Department of Anesthesia and Perioperative Care, School of Medicine, University of California, San Francisco, California 94143-0648, USA
Anesth Analg 102:1255-66. 2006..However, future investigations of sufficient study size and more standardized methods of defining outcomes are necessary to confirm the current findings... - Prognostic significance of postoperative in-hospital complications in elderly patients. II. Long-term quality of lifeKawalpreet Manku
Department of Anesthesia and Perioperative Care, University of California, San Francisco, USA
Anesth Analg 96:590-4, table of contents. 2003..The important independent predictors are co-morbid conditions, age, and new hospitalization after discharge... - Prognostic significance of postoperative in-hospital complications in elderly patients. I. Long-term survivalKawalpreet Manku
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California, USA
Anesth Analg 96:583-9, table of contents. 2003..9, P = 0.023). An effort to improve perioperative care delivery to elderly surgical patients must include measures to minimize in-hospital postoperative complications, particularly those involving the pulmonary and renal systems... - The prevalence of preoperative diastolic filling abnormalities in geriatric surgical patientsBridget Phillip
Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143-1605, USA
Anesth Analg 97:1214-21. 2003..These results suggest that evaluation of LV systolic function alone is not discriminatory in comprehensively characterizing LV function in geriatric surgical patients... - Histologic assessment of right atrial appendage myocardium in patients with atrial fibrillation after coronary artery bypass graft surgeryToshiko Nakai
Division of Cardiovascular Medicine, Nihon University School of Medicine, Tokyo, Japan
Cardiology 108:90-6. 2007..85). These results suggest that the age-related atrial fibrosis rather than cellular hypertrophy may be important in the pathogenesis of AF after CABG surgery and should be further investigated... - The effects of postoperative pain and its management on postoperative cognitive dysfunctionYun Wang
Department of Statistics, Purdue University, West Lafayette, Indiana 47907 2069, USA
Am J Geriatr Psychiatry 15:50-9. 2007..Those at least risk of experiencing POCD were those who received postoperative analgesia orally...
Research Grants
- AGING AND PERIOPERATIVE OUTCOMESJACQUELINE LEUNG; Fiscal Year: 2005..We believe that our studies will provide important results contributing ultimately to the improvement of perioperative outcomes in geriatric patients. ..
- Pathophysiology of postoperative delirium in older patientsJACQUELINE LEUNG; Fiscal Year: 2009..Our proposal meets with the major mission of the National Institute of Aging to reduce the burden of illness and disability in the elderly. ..
- Pathophysiology of postoperative delirium in older patientsJacqueline M Leung; Fiscal Year: 2010..Our proposal meets with the major mission of the National Institute of Aging to reduce the burden of illness and disability in the elderly. ..